Acute kidney injury (AKI) remains a crucial condition associated with poor prognosis in critically ill patients. Renal oxygenation resulting from...

AbstractBackground. Heart failure and chronic kidney disease (CKD) are biologically entwined and clinically difficult to disentangle. The 2026 Second Unive

Patients with end-stage kidney disease (ESKD) on dialysis face an increased risk of morbidity and mortality following SARS-CoV-2 infection, with concerns that their antibody response to COVID-19 vaccination may be lower than that of the general population. However, the effectiveness of the COVID-19 vaccination in ESKD patients remains unclear. This nationwide retrospective cohort study examined the association between COVID-19 vaccination and the risk of SARS-CoV-2 infection in ESKD patients on dialysis.

Infection-related glomerulonephritis (IRGN) is typically associated with bacterial infections, although viral and zoonotic pathogens are increasingly recognized. We report a rare case of IRGN in an im...

Nolan reports the results of a US study comparing the use of a polypill containing metoprolol succinate with enhanced usual care in people with symptomatic heart failure: the polypill group showed bet...

Fibrillary glomerulonephritis (FGN) is an uncommon form of kidney disease that can occasionally present in a diffuse crescentic variant. This may sometimes mimic antiglomerular basement membrane (anti...

ObjectivePosterior reversible encephalopathy syndrome (PRES) is a clinico-radiological syndrome characterised by seizures, hypertension, visual disturbances ...

AbstractObjective. To evaluate the efficacy of hemodynamic profiling (HDpro)-guided antihypertensive therapy in elderly patients with uncontrolled morning

Acute interstitial nephritis (AIN) is a frequent cause of acute kidney injury (AKI) and is commonly drug-induced. Corticosteroids are widely used for treatment; however, outcomes in cases with incompl...

Testing Tolvaptan versus 3% saline and the rate of rise of serum sodium in healthy volunteers.

IgA vasculitis (IgAV) is an immune-mediated disease characterized by the inflammation of small blood vessels because of the deposition of IgA1-dominant immune complexes. IgAV treatment primarily focus...

Alport syndrome (AS) is the most common inherited glomerular disease,1 caused by pathogenic (P) or likely pathogenic (LP) variants in three collagen IV genes: COL4A5, which leads to X-linked AS (XLAS)...

Gastrointestinal symptoms are common in patients undergoing hemodialysis (HD) and closely associated with mesenteric ischemia, a life-threatening condition with high mortality. Nonocclusive mesenteric...

How do you teach the immune system to recognize a cancer cell? Researchers are taking clues from the tumor itself, selecting unusual protein fragments and putting them into a vaccine.

Background Over the past two decades, chronic kidney disease (CKD) of unknown aetiology (CKDu) has emerged as a significant public health challenge in several tropical, low- and middle-income countrie...

Researchers identify the cytokine-mediated mechanism sustaining CD8+ T cell inflammation in lupus kidneys, opening pathways for targeted immunotherapy.

C3 glomerulonephritis (C3GN) is a rare glomerular disease caused by alternative complement pathway dysregulation. ANLN gene mutations have been previously associated with podocytopathies but not linke...