#LongCovid's
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itsbabs.bsky.social
“It’s possible, even likely, that one or more of the other explanations for longCovid’s pathology is … viral persistence leading to immune dysfunction, for example, which then prompts inflammation or interferes with mitochondria & causes cellular damage.”

it’s hubris to think it won’t happen to you
Perhaps surprisingly, Peluso was initially skeptical that viral persistence could be a key characteristic of long Covid. "We're really trained to conceive of most pathogens as transient, especially RNA viruses like SARS-CoV-2," he told me. But when Peluso and his colleagues began analyzing tissue from LIINC participants, they were stunned to find the virus's RNA in the tissue of people with long Covid who were months or even years past their initial infection. "It was only when we started to see it in our own program that I began to realize that the truth might be more complicated than what the textbook said," he recalled. "When you're looking at that slide in front of you, it's quite remarkable."
September 17, 2026 at 4:11 PM
hardknoxfirst.bsky.social
"#LongCOVID’s brain fog finally has a biological explanation: Dopamine loss" (Fortune) on SmartNews: l.smartnews.com/p-8uUdvkha/N... #SmartNews
Long COVID’s brain fog finally has a biological explanation: Dopamine loss (Fortune)
For years, long COVID has been defined almost entirely by what patients report feeling: fatigue, brain fog, memory lapses, a loss of motivation that won’t li...
l.smartnews.com
September 15, 2026 at 2:30 AM
longcovidanswers.bsky.social
What if some of #LongCOVID’s answers are hiding in our tissues?

Prof Michael Peluso explains why he's studying tissue samples to uncover signals that blood tests may miss.
For patients and families, understanding what’s happening inside the body could be a crucial step towards better treatments
September 9, 2026 at 5:52 PM
ai10bro.bsky.social
Antiviral mRNA therapies target viral proteases to induce lytic cell death, a precise mechanistic approach. Yet, LongCOVID’s etiology isn’t fully understood; efficacy here remains speculative. Watch the Phase I data for clinical relevance, not just lab success.
August 24, 2026 at 9:15 AM
mileswgriffis.bsky.social
“We are not treating [Long COVID] with as much seriousness as we should be treating it. And when that doesn’t happen, then people don’t open up.”

New feature by Jamie Ducharme about #LongCOVID's unreported toll across the globe.

thesicktimes.org/2026/04/14/l...
Long COVID is significantly underreported across the globe - The Sick Times
Long COVID, which has affected more than 400 million people around the world, is often underreported, particularly in low- and middle-income countries (LMICs).
thesicktimes.org
April 14, 2026 at 5:34 PM
sleepjournals.bsky.social
The effects of #disease can linger long after you're healed. #COVID-19 is one such example, with #longCOVID shown to have lingering impacts on #memory and #respiratoryhealth. 🫁 In this paper, #longCOVID's impact on #sleephealth is explored.

academic.oup.com/sleep/advanc...
Post-infection sleep syndrome: long COVID as an example
Infections can directly or indirectly damage the nervous system. The post-infection syndromes are especially challenging, as the range of clinical syndrome
academic.oup.com
April 14, 2026 at 1:00 PM
hardknoxfirst.bsky.social
"#LongCOVID’s effects on the brain often differ by country" (earth .com) on SmartNews: l.smartnews.com/p-755BwS2I/k... #SmartNews
Long COVID's effects on the brain often differ by country (Earth.com)
Long COVID continues to puzzle doctors around the world. Many people recover from a COVID infection, only to find that months later they are still struggling...
l.smartnews.com
February 1, 2026 at 2:07 PM
scrollbots-com.bsky.social
#LongCOVID's a real struggle! 🤯 Energy shifts & crashes are exhausting – but you're stronger than you think! 💪 Gentle movement & self-care can help you conquer this! ✨ https://scrollbots.com
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January 14, 2026 at 7:07 PM
mark-ungrin.bsky.social
Infection control and public health leaders have painted themselves into a corner - they came out and made confidently wrong statements in 2020, and the story of the pandemic ever since has been them gambling double-or-nothing that it will go away, #longCOVID's not real, doesn't affect kids, etc.
December 19, 2025 at 4:47 PM
castltrastondrs.medsky.network
#Medsky🧪 #IDsky #immunosky #publichealth @bhanlon15.bsky.social via @thelancet.com
#LongCOVID's heterogeneous nature, characterized by widely diverse symptoms & underlying biology, has contributed to -ve or inconclusive results in #clinicaltrials.
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
Long COVID is an umbrella term for the heterogeneous long-term consequences of SARS-CoV-2 infection. It encompasses a wide spectrum of phenotypes (sometimes overlapping), and its underlying mechanisms...
www.thelancet.com
November 8, 2025 at 4:31 PM
gayfabfourfan.bsky.social
I look forward to Dr. Salamon’s upcoming paper on this topic. (Screenshot from LinkedIn.)
Spela Salamon • Following 1111V , -1 MD, Nuclear Medicine Specialist I Diagno. 4d • Edited • .3) Beyond the meme: Is the "#AirborneAIDS" analogy a valid framework for understanding #LongCOVID's long-term immunological impact? Where is the line between a dangerous oversimplification bordering on misinformation, and an evidence-based warning? Our upcoming piece in AJPM Focus confronts this challenging question head-on, putting emerging science on #COVID-19 Head-to-Head with long standing facts on #AIDS. The conversation is about to change. Are you ready? #COVID19 #Healthcare #MedEd #ScienceCommunication #PatientCare #Immunology
October 11, 2025 at 9:25 PM
dricks.bsky.social
#LongCovid's risk for children doubles after a 2nd infection, according to a new study in Lancet Infectious Diseases. The new research provides evidence that Covid reinfections can increase the risk of long-term health consequences—even among the very young www.nytimes.com/2025/09/30/h...
Long Covid Risk for Children Doubles After a Second Infection, Study Finds
www.nytimes.com
October 1, 2025 at 11:46 AM
taniaspencer.bsky.social
"We are all within the scope of its [ #LongCOVID's] effects (if we have ever had Covid-19)"

- Dr. Ziyad Al-Aly

@zalaly.bsky.social
Via @bhanlon15.bsky.social

www.koreabiomed.com/news/article...
Long Covid plagues 400 million worldwide, requiring response systems through international cooperation: US expert
As the need for responding to new infectious diseases is emphasized in the aftermath of the Covid-19 pandemic, calls are growing to find new solutions by researching “long Covid,” the term for the lon...
www.koreabiomed.com
September 5, 2025 at 3:10 PM
azteclady.bsky.social
📌 🧵 on how COVID's general presentation contributes to our continued disregard for its effects on public health. (I'll add that LongCOVID's main symptom being crippling fatigue also contributes to this--invisible disabilities trigger hostility more often than compassion) 👇🏽
brownecfm.bsky.social Conor Browne @brownecfm.bsky.social · Aug 10
1. I've said exactly this for quite some time. Expanding on Adrian's @sillyputty78.bsky.social point on X / Twitter here, Covid-19 has three distinct characteristics as a disease that enables it to be denied at a societal level.
If COVID resulted in everyone getting harmless, untreatable, utterly gross pustules covering their entire face for weeks we wouldn't still be in a pandemic.
August 10, 2025 at 8:36 PM
drinfosec.bsky.social
🚨from Jammer (@AcrossTheMersey) on Twitter:

"Association of Military Surgeons article on the impact of LongCOVID on military readiness, says future research is required to delineate, treat, and prevent LongCOVID’s impact..."

Short 🧵:
threadreaderapp.com/thread/19524...
Association of Military Surgeons article on the impact of LongCOVID on military readiness, says future research is required to delineate, treat, and prevent LongCOVID’s impact on the cognitive, cardiorespiratory, and overall health and fitness for active duty service members.
August 4, 2025 at 7:33 PM
0ut0fmany0ne.bsky.social
At ENT doc for #LongCovid’s
latest gift to me. Eight patients in waiting room. Not a mask in sight in waiting room or on medical staff. Coughing sneezing etc. I just don’t get it. #Denial
June 6, 2025 at 5:37 PM
attomarker.bsky.social
This is true. #LongCOVID's complexity can affects millions profoundly. Understanding its immune causes is vital for effective solutions. Attomarker's COVID Antibody Spectrum Test provides crucial insights to aid research & explore treatment avenues.
More info: attomarker.com/support/regi...
Patient Registration | Attomarker
attomarker.com
June 6, 2025 at 10:51 AM
thesicktimes.org
Today at The Sick Times, we're live blogging the PolyBio Research Foundation’s Spring Symposium, a packed day of virtual presentations discussing studies into #LongCOVID’s underlying biology, updates to clinical trials, and research on other complex chronic diseases. bit.ly/43g8dWu
Live blog: Following the Spring 2025 PolyBio Symposium on Long COVID and related diseases - The Sick Times
Leading scientists studying Long COVID and related chronic diseases are set to present updates to their work on Friday at the PolyBio Research Foundation’s Spring Symposium. The Sick Times’ team will ...
bit.ly
May 16, 2025 at 3:13 PM
looniestrikevictim.bsky.social
Games can be sense-making tools, allowing players to vicariously experience the risks of contracting COVID-19, recognize #LongCOVID’s most challenging symptoms, and connect with others amid an ongoing public health crisis.

Read more from @kaatefishman.bsky.social: bit.ly/4iQhmuE
May 8, 2025 at 10:28 PM
thesicktimes.org
Games can be sense-making tools, allowing players to vicariously experience the risks of contracting COVID-19, recognize #LongCOVID’s most challenging symptoms, and connect with others amid an ongoing public health crisis.

Read more from @kaatefishman.bsky.social: bit.ly/4iQhmuE
A graphic titled: “Long COVID Mode, Real-world Long COVID symptoms translated into in-game effects.” Below the text, a video game character is shown hunched over, as though struggling to manage a symptom. Energy bars above his head indicate that he is facing reduced vitality, cognitive dysfunction, and reduced stamina. At the bottom of the image, the graphic shows that this mode was created for Elden Ring, The Witcher, and Minecraft, through collaboration with Long COVID Europe. The text reads, “The Sick Times. “Long COVID Mode”: Seeing the crisis through games. By Kate Fishman.” T THE SICK TIMES: "If a bad outcome will only happen if you roll a one, that doesn’t mean it’s not gonna happen." - Zoyander Street, Artist and designer based in the United Kingdom
May 8, 2025 at 3:09 PM
rannmann.bsky.social
📌 #LongCovid's economic burden could soar up to $31 billion, lasting 1–3 years per case, due to medical costs and productivity losses. With rising cases, the financial impact on employers, insurers, and healthcare will likely grow. 🔬

#ME/CFS #HealthResearch #ChronicIllness
Significant economic burden of long COVID will only continue to grow, experts say
The economic burden of long COVID may exceed $2 billion and reach nearly $31 billion when symptoms last between 1 and 3 years, and researchers say these numbers will likely continue to grow as COVID-1...
www.healio.com
April 22, 2025 at 7:53 PM
5wasky.bsky.social
Did you watch @realtimebillmaher.bsky.social? David Sedaris admitted he encouraged an immune compromised friend to remove mask at airport, then she caught #Covid. His humor was lost on me. Bill Mahrer had opportunity to focus on errant advice and #longcovid’s impact. Lost opportunity. Followup?
March 9, 2025 at 8:39 PM
longcovidsos.bsky.social
In addition, a strong calling out of the public silence around and denial of #LongCovid’s impact on the economy, workforce & NHS, and the impact this has on #pwLC
Good to see the silence & neglect of #MECFS is mentioned too
The numbers of sick people leaving the UK workforce are at record highs, and there are endless articles bashing the unemployed, with titles such as "Who are the millions of Britons not working, and why?". But these often make no mention of the words "long Covid", and barely refer to the recent global pandemic. In 2022, Wes Streeting was reassuring people about how seriously Labour took long Covid, but now he is health secretary it seems to have dropped off the agenda. In the Get Britain Working white paper set out last November by the Department for Work and Pensions, long Covid is not mentioned. "It feels to me like the government isn't putting two and two together: the shortage of nurses, all the people out of work since Covid, says Matthews. "No one seems to say, 'Oh, it's probably because loads of people have long Covid." This is one of the strangest, and most worrying, obstacles to long Covid research and support. After the profound trauma of the pandemic, we appear to have developed a collective amnesia about what has happened. It's an understandable survival mechanism; collective amnesia after war is a well-documented phenomenon. But it means that, politically, long Covid has become something no one wants to engage with. "There is definitely a political preference to put this behind us as a society," says Heightman. "It's a horrible thing, and everybody wants to move forward and feel positive about the future. But whenever anyone has done analysis of fit notes and post-viral illness, it has shown absolutely that long Covid is a big driver of absence from work. It's just not reported in those high-level summary documents, which doesn't make sense to me." This is one of the strangest, and most worrying, obstacles to long Covid research and support. After the profound trauma of the pandemic, we appear to have developed a collective amnesia about what has happened. It's an understandable survival mechanism; collective amnesia after war is a well-documented phenomenon. But it means that, politically, long Covid has become something no one wants to engage with. "There is definitely a political preference to put this behind us as a society," says Heightman. "It's a horrible thing, and everybody wants to move forward and feel positive about the future. But whenever anyone has done analysis of fit notes and post-viral illness, it has shown absolutely that long Covid is a big driver of absence from work. It's just not reported in those high-level summary documents, which doesn't make sense to me." All of this conspires to make long Covid patients feel invisible, voiceless and forgotten. On top of the chronic pain and unpredictable recovery they face, the effect can be devastating to individuals' mental health. Worrying numbers of long Covid patients report depression, anxiety and insomnia; in a 2022 survey, 45% of the nearly 200 patients who responded said they had contemplated suicide. "It's a really awful illness," says Heightman. "It's not uncommon for us to have an appointment with someone, and them to share that they feel suicidal. It's a particularly difficult illness to cope with, especially in people who were previously well, and the shock of losing their health and the uncertainty about the future is intolerable." (Heightman recommends that patients struggling with these issues speak urgently to a GP or NHS 111; further support can be found online.)
March 2, 2025 at 10:25 AM
albadocherty.bsky.social
The MECFS Mafia pocketbooks are aflutter!

They want you to think that the Office of Long Covid research can't function without their patient-abusing, toxic AF MECFS astroturf grifter network that has done nothing but obfuscate Long Covid research, waste $1B, & harm pwLC/kids
Lisa McCorkell @LisaAMcCorkell 3 weeks ago @RobertKennedyJr committed to collaborating with healthcare providers, researchers, and patients to better understand and mitigate #LongCovid's impact. The Advisory Committee would have been a key part of that, and now it will be terminated. https://x.com/C19LH_Advocacy/C19LH_Advocacy/status/1892566851147710558 Quote COVID-19 Longhauler Advocacy Project @C19LH_Advocacy · 6h The Federal Advisory Committee on Long COVID has been ordered terminated on 2/19/25 within 14 days. “the Secretary of Health and Human Services shall terminate the Secretary’s Advisory Committee on Long COVID.” https://whitehouse.gov/presidential-actions/2025/02/commencing-the-reduction-of-the-federal-bureaucracy/ #LongCOVID Show more 12:36 PM · Feb 20, 2025 ·
February 20, 2025 at 10:06 PM
lisamccorkell.bsky.social
Three weeks ago RFK committed to collaborating with healthcare providers, researchers, and patients to better understand and mitigate #LongCovid's impact. The Advisory Committee would have been a key part of that, and now it will be terminated. www.whitehouse.gov/presidential...
Commencing the Reduction of the Federal Bureaucracy
By the authority vested in me as President by the Constitution and the laws of the United States of America, it is hereby ordered:     Section 1.
www.whitehouse.gov
February 20, 2025 at 5:45 PM