why would they give norepinephrine's color to acetylcholine 🙄

"In this study, we describe how enhancing norepinephrine’s action on microglia can mitigate early inflammatory changes & neuronal injury in Alzheimer’s models,” Ania Majewska, PhD, senior author of study

Visit our art gallery 🎨👉 bit.ly/42OnyOW
Original artwork by @charmainela.bsky.social

Aakash Basu is a grad student in the Kaye Lab 🥼whose work was published in Biological Psychiatry!✍️ Aakash investigates norepinephrine's function in the frontal cortex 🧠 & proposes its role in aversive learning ❌

Read more about his goals & research here 👇[2/3]

The causal manipulation exists, Lefton deleted adrenergic receptors specifically in astrocytes and abolished norepinephrine's synaptic effects entirely.

Three independent methods.

That's the do(astrocyte) intervention that would disambiguate Carandini's correlational finding

I was careful on the dopamine end of the pathway, since norepinephrine's converted into dopamine I didn't want to accidentally spike my norepinephrine again until I knew for sure I had it under control.

I focused first on the cortisol end of the feedback loops

1/3

For sure! I’ve been trying to lay out flowcharts of physiological effects of corts for years now (one of the steroids I study), it’s so complicated! Both perpetuates norepinephrine’s functions and perhaps is part of the feedback loop? I wonder how much short-term glucose spikes are helpful?

#psynomCABN Special Issue! Discover how catecholaminergic drugs impact choice behavior, shedding light on #dopamine and #norepinephrine's role. @AnnaLiley @SimonNeuroLab #DecisionMaking bit.ly/3JWVheM

Norepinephrine's Role in Anxiety Behaviors Uncovered
www.news-medical.net/post.aspx?id...