Arshiya Sangchooli (They/he)
arshiyasan.bsky.social
Arshiya Sangchooli (They/he)
@arshiyasan.bsky.social
🧠 Neuroscientist, PhD candidate, lapsed MD
🇦🇺 Monash (Neural Systems and Behaviour Lab), ex Uni Melbourne, Tehran Uni
👨‍🔬Computational modelling, spatial patterns, MRI processing, tractography, cog-neuro, addiction
AuDHD 🌈
English & Persian flavors
Reposted by Arshiya Sangchooli (They/he)
There are many MRI approaches for studying myelin. But which ones are reliable, how do they relate to each other, and how do they behave in gray vs white matter?

In our new preprint, we introduce Myelin Imaging Reliability and ReprOducibility Resource (MIRROR) 🧠🪞

📄🔗 www.biorxiv.org/content/10.6...
October 1, 2026 at 12:57 PM
Reposted by Arshiya Sangchooli (They/he)
Our multilayer MEG paper is out today in Nature Communications: depth-resolved laminar inference in humans 🧠#neuroskyence
www.nature.com/articles/s41...
Multilayer MEG source modelling enables depth-resolved laminar inference in humans - Nature Communications
Researchers developed a multilayer MEG framework that estimates activity across cortical depth non-invasively. Simulations and three human datasets show when reliable laminar inference is possible, en...
www.nature.com
September 30, 2026 at 9:29 AM
Reposted by Arshiya Sangchooli (They/he)
Today I'm releasing the "1000×1000 collection": a unified place to learn about dynamical structure. 1000 simulated time series (1000 samples each) spanning 133 dynamical processes.

Have a play? 🐛

#timeseries #dynamicalsystems #complexity #opendata

dynamicsandneuralsystems.github.io/1000x1000/
September 29, 2026 at 12:05 AM
Reposted by Arshiya Sangchooli (They/he)
We’re excited to share BrainWideBench, a new benchmark for evaluating how models of neural activity generalize across animals and tasks!

📄 Check out the paper here! arxiv.org/abs/2609.22064

Special shoutout to @alx-adr.bsky.social, who contributed equally as co-first authors!
September 21, 2026 at 6:12 PM
Reposted by Arshiya Sangchooli (They/he)
I ♥ Quarto... whether for mathy notes, or writing models a collaborator needs in a Word doc, I find it to be such a handy way to combine prose and math. I've been using it since @russpoldrack.org introduced me to it, and happy to share my templates to help others use it github.com/nicholst/Ihe...
GitHub - nicholst/IheartQuarto: Templates to use Quarto for writing short technical documents
Templates to use Quarto for writing short technical documents - nicholst/IheartQuarto
github.com
September 3, 2026 at 2:13 PM
Reposted by Arshiya Sangchooli (They/he)
Gene Gradients Reveal Directed Structural Connectivity Across Species | bioRxiv www.biorxiv.org/content/10.6...
August 30, 2026 at 6:06 AM
Reposted by Arshiya Sangchooli (They/he)
My best student experiences came from take-home problems I could think about for weeks. Hard to incentivize this outcome for today's students with AI to generate full solutions.

I gave a talk on a model that aims to 'save' take-home assignments:
🎥 www.youtube.com/watch?v=slg0...

#physics #highered
August 28, 2026 at 6:18 AM
Reposted by Arshiya Sangchooli (They/he)
Deeply worrying to see hundreds of postdocs in Argentina left in limbo by budget cuts and delays.

Science cannot thrive when talented early career researchers face such uncertainty after years of training.

www.science.org/content/arti...
Budget cuts and delays leave hundreds of Argentine postdocs in limbo
Many scientists are scrambling to make ends meet and reconsidering their future in research
www.science.org
August 15, 2026 at 9:58 AM
Reposted by Arshiya Sangchooli (They/he)
How do you build a brain from a genome? We know a lot about the mechanisms and molecules

Here we revisit the algorithmic problem: What kinds of programs can specify a brain within the genome’s information budget and the finite time available for development?

stankerstjens.github.io/could-a-comp...
Could a computer scientist build a brain?
How does a brain wire itself, starting from a single cell, using only the information encoded in a genome? We pose this as an engineering problem.
stankerstjens.github.io
August 14, 2026 at 6:21 PM
Reposted by Arshiya Sangchooli (They/he)
Reposted by Arshiya Sangchooli (They/he)
Morphogenesis has a memory problem. A tissue must form reproducible shape while remaining robust to noise arising across scales. How does the target geometry survive?

New work led by Nico Romeo, with @davidbruckner.bsky.social:
arxiv.org/abs/2607.23907
Growth and remodeling control shape memory in morphogenetic rods
Mechanical instabilities provide a general design principle for shaping developing organs and engineering soft materials. However, in slender structures, simple elastic buckling tends to erase rather ...
arxiv.org
August 13, 2026 at 1:58 PM
Reposted by Arshiya Sangchooli (They/he)
Check out our new paper! 🧠

Me, @xiongbowu.bsky.social and @fuentemilla.bsky.social review how reactivation at the end of events support memory formation and propose it serves multiple functions from preventing interference to helping preserve temporal continuity! ✨

www.cell.com/trends/cogni...
Neural reactivation supports memory formation when events end
Memory routinely transforms continuous experience into discrete episodes that support flexible retrieval. We propose that these structured representations are established via rapid neural reactivation...
www.cell.com
August 12, 2026 at 3:17 PM
Reposted by Arshiya Sangchooli (They/he)
Applications are open for the 2026–27 Black In Neuro Mentorship Cohort! 🧠✨

Apply as a mentor or mentee for 1:1 matching, application support, professional development & a global neuro community.

📲 Scan the QR code to apply! #BlackInNeuro
August 12, 2026 at 8:56 PM
Reposted by Arshiya Sangchooli (They/he)
Now in Science: How does the brain’s navigation system allocate its limited representational resources during behavior?

We found that grid cells sweep toward locations of interest, providing a potential mechanism for allocating spatial attention in the cognitive map.🧵

science.org/doi/10.1126/...
August 6, 2026 at 6:01 PM
Reposted by Arshiya Sangchooli (They/he)
Happy to share the CA3 dataset is published. First large-scale dense connectomics from hippocampus. First connectomic dataset imaged in @princetonneuro.bsky.social. A harbinger of many larger datasets to come (for both). doi.org/10.1038/s415... #hippocampus But my personal favorite is (1/2)
Hippocampal CA3 connectomics reveals a gradient of mossy fiber inputs and selective feedforward inhibition onto pyramidal cells - Nature Neuroscience
The authors present a dense connectomic reconstruction of a 0.1 mm3 hippocampal CA3 volume and reveal spatial gradients, high convergence and cell-type-selective feedforward inhibition of inputs to py...
doi.org
August 7, 2026 at 2:41 AM
Reposted by Arshiya Sangchooli (They/he)
Want to support Australian science? Sign off on this great initiative from @science.org.au !

restorescience.com.au
Back Australia's Ability
Help us restore investment in Australian science
restorescience.com.au
July 24, 2026 at 12:35 AM
Reposted by Arshiya Sangchooli (They/he)
This is one of my favourite things. Direct replication of MEG and fMRI findings in intracranial recordings and a demonstration that cortical representations update in the right direction around hippocampal ripples.
For a long time I felt like there was a hesitation in neuroscience to ascribe anything like a planning function to the various "replay" events we see in the hippocampus, but I think this is rapidly changing.

Here's another new entry in human epilepsy patients:

www.nature.com/articles/s41...

🧠📈 🧪
Human hippocampal ripples coordinate planning sequences and compositional representations in neocortex - Nature Neuroscience
Human hippocampal ripples and replay interact with the prefrontal cortex to update mental representations online, letting the brain compositionally combine familiar elements in new ways for flexible p...
www.nature.com
July 7, 2026 at 7:51 PM
Reposted by Arshiya Sangchooli (They/he)
📘 The OHBM 2026 Abstract Book is now available!

Relive the science of #OHBM2026 by exploring the full collection of abstracts presented at this year’s Annual Meeting in Bordeaux.

🔗Access the Abstract Book here: humanbrainmapping.org/aperture-neu...
July 1, 2026 at 3:04 PM
Reposted by Arshiya Sangchooli (They/he)
This paper is an absolutely beautiful combination of a deep set of cognitive ideas, a super creative task, a surprisingly impressive behaviour, and an elegant modelling framework. One of my favourite things in the last year.
June 27, 2026 at 5:55 AM
Reposted by Arshiya Sangchooli (They/he)
Great. Goes well with this paper on how to write bad papers:
doi.org/10.1111/j.00...
June 25, 2026 at 6:20 AM
Reposted by Arshiya Sangchooli (They/he)
🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly
www.nature.com/articles/s41... rdcu.be/fqa92
June 24, 2026 at 4:44 PM
Reposted by Arshiya Sangchooli (They/he)
Happy to share that our paper on objective quality assessment for "precision" fMRI is now out in @cp-neuron.bsky.social

A recap of what it does, what's new since the preprint, and code you can run on your own data.

cell.com/neuron/fullt...
June 22, 2026 at 5:22 PM
Reposted by Arshiya Sangchooli (They/he)
If you're in London and want to sit in air conditioning (so I am told) tomorrow afternoon, you can also get a free lecture out of it!

Come join me to talk about consciousness, neuroscience, & adversarial collaborations tomorrow afternoon at the Crick!

www.eventbrite.co.uk/e/understand...
Understanding the brain in theory and practice
A series of interactive workshops on building better experiment-theory collaborations in neuroscience.
www.eventbrite.co.uk
June 24, 2026 at 11:06 AM
Reposted by Arshiya Sangchooli (They/he)
Distinct Brain Maturation Pathways Relate Environmental Variation to Cognitive Development | bioRxiv www.biorxiv.org/content/10.6...
June 21, 2026 at 10:56 PM