Taco subo
@averagedoc.bsky.social
Ordinary cardiologist. Extraordinary prior auth filler outer.
If I had to pick, I think I’d go for a bleed rather than an infarct, not reassuring that death was 3x higher in monotherapy group
September 7, 2026 at 9:33 PM
If I had to pick, I think I’d go for a bleed rather than an infarct, not reassuring that death was 3x higher in monotherapy group
So much for Mendelian randomization #cardiosky
An experimental heart drug failed in a clinical trial, stunning cardiologists who thought it would be the missing link.
The Heart Drug Pelacarsen Fails, Shocking Novartis and Cardiologists
Doctors were hopeful the drug, which was being tested in a large clinical trial by Novartis, was going to be a powerful new tool to fight heart disease.
nyti.ms
September 5, 2026 at 1:38 AM
So much for Mendelian randomization #cardiosky
Guess this explains why the abc score guided trial didn’t work. Doac for everyone!
In patients with atrial fibrillation and intermediate stroke risk, direct oral anticoagulation led to a lower risk of stroke, systemic embolism, major bleeding, or death from cardiovascular causes than no anticoagulation. Full SINGLE-AF trial results: https://nej.md/4ii61XB
#ESCCongress
#ESCCongress
August 28, 2026 at 8:28 PM
Guess this explains why the abc score guided trial didn’t work. Doac for everyone!
What’s the rule on systematic reviews in a LLM world? Are we still publishing keywords searched and pretending that we looked through 11000 citations to come up with 5 to include in a meta analysis or can we just ask claude to do it and take 5 seconds? #medsky #cardiosky
August 22, 2026 at 12:09 PM
What’s the rule on systematic reviews in a LLM world? Are we still publishing keywords searched and pretending that we looked through 11000 citations to come up with 5 to include in a meta analysis or can we just ask claude to do it and take 5 seconds? #medsky #cardiosky
Reposted by Taco subo
If you have time to browse bluesky this weekend, you have time to submit your comment on the proposed OMB rule to politicize science funding agencies. This one is important. Here's my comment if some inspiration will help. 🧪
scienceforeveryone.science/submit-your-...
scienceforeveryone.science/submit-your-...
Submit your OMB comment this weekend.
This one is important. It's due on Monday.
scienceforeveryone.science
July 11, 2026 at 4:36 PM
If you have time to browse bluesky this weekend, you have time to submit your comment on the proposed OMB rule to politicize science funding agencies. This one is important. Here's my comment if some inspiration will help. 🧪
scienceforeveryone.science/submit-your-...
scienceforeveryone.science/submit-your-...
Sewing needles are not part of a heart healthy diet #medksy
“Needle in the Heart”—when an artefact tells the real story
A 51-year-old man with a BMI of 35 presented with progressive exertional dyspnoea and chest pain. Medical history included hypertension, type 2 diabetes, a
academic.oup.com
July 7, 2026 at 11:41 AM
Sewing needles are not part of a heart healthy diet #medksy
Tantalizing results. Would love to see another crack at this trial with an wearable device, not an easy sell to put 2 generators in a patient #cardiosky
Vagal Nerve Stimulation in Patients With Heart Failure and Reduced Ejection Fraction: The ANTHEM-HFrEF Trial
www.jacc.org
July 2, 2026 at 5:37 PM
Tantalizing results. Would love to see another crack at this trial with an wearable device, not an easy sell to put 2 generators in a patient #cardiosky
Love the aphorism but looks like you can stuff your face all the way to a normal left atrial volume #cardiosky #medsky
Assessing Left Atrial Volume Indexation to Predict Mortality in Individuals With Overweight and Obesity | Circulation: Cardiovascular Imaging
BACKGROUND: Alternative indexation methods for left atrial volume (LAV) have been proposed to
achieve better proportional scaling than the current standard body surface area indexation.
However, there...
www.ahajournals.org
June 28, 2026 at 10:30 PM
Love the aphorism but looks like you can stuff your face all the way to a normal left atrial volume #cardiosky #medsky
Anyone else just reporting strain as a positive number because they don’t give a fuck? #cardiosky
June 22, 2026 at 10:08 PM
Anyone else just reporting strain as a positive number because they don’t give a fuck? #cardiosky
Reposted by Taco subo
Someone has been projecting images all over D.C. “It’s swampier than ever.” The Kennedy Center one is pretty hilarious. 😂😂😂
June 21, 2026 at 10:52 PM
Someone has been projecting images all over D.C. “It’s swampier than ever.” The Kennedy Center one is pretty hilarious. 😂😂😂
Is this curtains for tavr outside of high risk or do we hand wave and say no one uses xt anymore anyways ?#cardiosky
www.jacc.org
June 18, 2026 at 6:24 PM
Is this curtains for tavr outside of high risk or do we hand wave and say no one uses xt anymore anyways ?#cardiosky
Fuck it, let’s just google
As you may have seen - Open Evidence and UpToDate expert AI (specialized in medicine) lose to GPT/Claude/Gemini = generalized models
www.nature.com/articles/s41...
Why does #Roon think they will be special when they eventually sell MD discussions into an LLM package? 🤔
#MedSky
www.nature.com/articles/s41...
Why does #Roon think they will be special when they eventually sell MD discussions into an LLM package? 🤔
#MedSky
June 15, 2026 at 1:29 AM
Fuck it, let’s just google
I got you now bitches! Go on, deny my Zepbound script! Go on! @bcbsm.bsky.social #cardiosky
June 13, 2026 at 12:03 AM
I got you now bitches! Go on, deny my Zepbound script! Go on! @bcbsm.bsky.social #cardiosky
High rest mbf is ….not…good? #cardiosky
Stress and rest myocardial blood flow to complement myocardial flow reserve in risk prediction for patients being evaluated for known or suspected coronary artery disease
AbstractAims. Although the clinical value of myocardial flow reserve (MFR) is well-established, whether additional incorporation of rest and stress myocard
academic.oup.com
June 12, 2026 at 11:24 PM
High rest mbf is ….not…good? #cardiosky
Looks like we’re gonna shorten the PYP protocol to scan at 30 minutes post injection #cardiosky
Kinetics of Technetium-Labeled Cardiac Amyloid Radionuclide Imaging | Circulation: Cardiovascular Imaging
BACKGROUND: Technetium-labeled bone-avid tracers have been repurposed to diagnose transthyretin
cardiac amyloidosis without rigorous kinetic studies. Supply shortages have necessitated
the use of hydr...
www.ahajournals.org
June 8, 2026 at 2:32 AM
Looks like we’re gonna shorten the PYP protocol to scan at 30 minutes post injection #cardiosky
Anyone else hear arguments from docs against glp1as because lack of long term data? What is this future black box post marketing boogeyman? When has a drug ever had a positive cvot and then come back later with cancer concerns or something ? #medsky
June 4, 2026 at 12:50 PM
Anyone else hear arguments from docs against glp1as because lack of long term data? What is this future black box post marketing boogeyman? When has a drug ever had a positive cvot and then come back later with cancer concerns or something ? #medsky
Reposted by Taco subo
🧵 Public science in the US has taken some heavy hits over the last year, but the White House OMB is proposing a series of changes that will result in a TKO for science as we know it unless we fight back. Here's what's happening, and why it matters. 1/n
May 29, 2026 at 7:04 PM
🧵 Public science in the US has taken some heavy hits over the last year, but the White House OMB is proposing a series of changes that will result in a TKO for science as we know it unless we fight back. Here's what's happening, and why it matters. 1/n
It’s not about the significance of the results that matter for nejm, it’s about how many patients got randomized. Want to test for a difference between 81 mg aspirin and 100 mg aspirin ? Who cares about the result, as long as you had n of 10000 nejm will
Publish
Publish
Our latest video in our partnership with @glaucomflecken.bsky.social summarizes the Ez-PAVE trial that evaluated the appropriate LDL cholesterol target for secondary prevention in patients with atherosclerotic cardiovascular disease. Read the full study for free: https://nej.md/DrG41
#Cardiology
#Cardiology
May 27, 2026 at 5:35 PM
It’s not about the significance of the results that matter for nejm, it’s about how many patients got randomized. Want to test for a difference between 81 mg aspirin and 100 mg aspirin ? Who cares about the result, as long as you had n of 10000 nejm will
Publish
Publish
Pretty low rates of Scd for Hocm. How high does it need to be to make icd a solid choice without dedicated rcts? Looks like only the top 1% of scar would warrant it, even then, Rct would be good #cardiosky
pubmed.ncbi.nlm.nih.gov/42113540/
pubmed.ncbi.nlm.nih.gov/42113540/
May 25, 2026 at 10:30 AM
Pretty low rates of Scd for Hocm. How high does it need to be to make icd a solid choice without dedicated rcts? Looks like only the top 1% of scar would warrant it, even then, Rct would be good #cardiosky
pubmed.ncbi.nlm.nih.gov/42113540/
pubmed.ncbi.nlm.nih.gov/42113540/
No argument I can give can offset nocebo, I say they’re safer than Tylenol, doesn’t work. the solution is to make statins available over the counter. #cardiosky
Time to Move Beyond the Statin Nocebo Effect | JACC www.jacc.org/doi/10.1016/...
Time to Move Beyond the Statin Nocebo Effect | JACC www.jacc.org/doi/10.1016/...
Time to Move Beyond the Statin Nocebo Effect:
www.jacc.org
May 23, 2026 at 8:22 PM
No argument I can give can offset nocebo, I say they’re safer than Tylenol, doesn’t work. the solution is to make statins available over the counter. #cardiosky
Time to Move Beyond the Statin Nocebo Effect | JACC www.jacc.org/doi/10.1016/...
Time to Move Beyond the Statin Nocebo Effect | JACC www.jacc.org/doi/10.1016/...
Say it with me : quintuple therapy! (Sorry Vericiguat I think you’re great but the guidelines…) #cardiosky
Efficacy and Safety of Digitalis Glycosides in Heart Failure
This meta-analysis assesses the association of digitalis glycosides treatment with risk of the composite outcome of cardiovascular death or first worsening heart failure events in patients with heart ...
jamanetwork.com
May 23, 2026 at 7:59 PM
Say it with me : quintuple therapy! (Sorry Vericiguat I think you’re great but the guidelines…) #cardiosky
So apparently Wegovy is gonna be $50 for all Medicare beneficiaries starting July 1. How long before the senior citizen black market opens up shop? #medsky
May 20, 2026 at 12:33 AM
So apparently Wegovy is gonna be $50 for all Medicare beneficiaries starting July 1. How long before the senior citizen black market opens up shop? #medsky
I guess if someone already has a foley this is fine but condom Cath would have made more sense
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
May 17, 2026 at 3:44 AM
I guess if someone already has a foley this is fine but condom Cath would have made more sense
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...