Ben Carty
@bencarty.bsky.social
Wellcome Early Career Fellow, Jansen lab, University of Oxford | Christ Church, Oxford | All things (neo)centromeres and chromatin
Reposted by Ben Carty
In this episode we speak with @robklose.bsky.social, Professor of Genetics at the University of Oxford, about how CpG islands help control gene expression and chromatin regulation during development. #podcast #epigenetics
Listen here: activemotif.com/podcasts-rob...
Listen here: activemotif.com/podcasts-rob...
September 25, 2026 at 7:00 AM
In this episode we speak with @robklose.bsky.social, Professor of Genetics at the University of Oxford, about how CpG islands help control gene expression and chromatin regulation during development. #podcast #epigenetics
Listen here: activemotif.com/podcasts-rob...
Listen here: activemotif.com/podcasts-rob...
Reposted by Ben Carty
Sometimes the best medicine is just hanging out with a bunch of scientists
September 9, 2026 at 8:07 PM
Sometimes the best medicine is just hanging out with a bunch of scientists
Katie Taylor, queen of Ireland
Katie Taylor makes her FINAL emotional ring walk at Croke Park!
YouTube video by DAZN Boxing
youtu.be
September 6, 2026 at 8:40 PM
Katie Taylor, queen of Ireland
Reposted by Ben Carty
Reposted by Ben Carty
The kinetochore is essential for cell division across species, but its components and organization evolve dramatically. How can that be? Our first foray into this fascinating question is up now on biorxiv: 🧪 1/12
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Kinetochore diversification in Naegleria reveals plasticity in the kinetochore-microtubule interface
The kinetochore--the molecular machine that couples chromosomes to spindle microtubules--performs an essential, tightly regulated function, yet varies dramatically across eukaryotes. Microtubules are ...
www.biorxiv.org
August 19, 2026 at 6:58 PM
The kinetochore is essential for cell division across species, but its components and organization evolve dramatically. How can that be? Our first foray into this fascinating question is up now on biorxiv: 🧪 1/12
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Ben Carty
These two reviews on centromeres and kinetochores in @natrevmcb.nature.com cap off @andrea-musacchio.bsky.social sabbatical at @stanfordbiochem.bsky.social from @valleefoundation.bsky.social. Long time in the making! Non-paywall versions rdcu.be/fxD9V, rdcu.be/fxEar
Structure and function of the centromere and inner kinetochore
Nature Reviews Molecular Cell Biology - The kinetochore is a macromolecular complex that assembles on centromeric chromatin and connects spindle microtubules to the chromosome. This Review...
rdcu.be
August 3, 2026 at 6:54 PM
These two reviews on centromeres and kinetochores in @natrevmcb.nature.com cap off @andrea-musacchio.bsky.social sabbatical at @stanfordbiochem.bsky.social from @valleefoundation.bsky.social. Long time in the making! Non-paywall versions rdcu.be/fxD9V, rdcu.be/fxEar
Reposted by Ben Carty
🚨🚨NEW PREPRINT ALERT!🚨🚨Proud to present our recent study, out now on bioRxiv, in which we reveal an RNA-dependent positive feedback loop that drives malignant ribosome biogenesis and tumour growth (1/15).
🔗
www.biorxiv.org/content/10.6...
🔗
www.biorxiv.org/content/10.6...
July 3, 2026 at 7:18 PM
🚨🚨NEW PREPRINT ALERT!🚨🚨Proud to present our recent study, out now on bioRxiv, in which we reveal an RNA-dependent positive feedback loop that drives malignant ribosome biogenesis and tumour growth (1/15).
🔗
www.biorxiv.org/content/10.6...
🔗
www.biorxiv.org/content/10.6...
Reposted by Ben Carty
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes:
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
June 5, 2026 at 4:02 PM
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes:
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
Reposted by Ben Carty
There is still time to book your ticket for our 2nd Annual Centre for Epigenetics Conference 2026! To book your ticket and find out more information, please follow this link: eshop.qmul.ac.uk/conferences-...
#epigenetics #conference #qmul
#epigenetics #conference #qmul
May 27, 2026 at 9:38 AM
There is still time to book your ticket for our 2nd Annual Centre for Epigenetics Conference 2026! To book your ticket and find out more information, please follow this link: eshop.qmul.ac.uk/conferences-...
#epigenetics #conference #qmul
#epigenetics #conference #qmul
Reposted by Ben Carty
Today we celebrate our colleagues Colin Kleanthous and Rob Klose as they join the Fellowship of the Royal Society, one of the highest honours in the scientific world, in recognition of their impactful contributions to knowledge. Congratulations! 👏 👏 👏
Read more ⬇️
Read more ⬇️
Congratulations to Colin Kleanthous and Rob Klose on joining the Fellowship of the Royal Society
The two scientists have been selected for outstanding contributions to their fields
bit.ly
May 27, 2026 at 10:18 AM
Today we celebrate our colleagues Colin Kleanthous and Rob Klose as they join the Fellowship of the Royal Society, one of the highest honours in the scientific world, in recognition of their impactful contributions to knowledge. Congratulations! 👏 👏 👏
Read more ⬇️
Read more ⬇️
Reposted by Ben Carty
We are looking for a new colleague to join us in Galway. The position is in Biochemistry and if research focus lines up we hope the successful person will join us in the Centre for Chromosome biology (chromosome.ie). Reach out if you are interested in applying!
tinyurl.com/2jy4rj3r
tinyurl.com/2jy4rj3r
May 20, 2026 at 12:06 PM
We are looking for a new colleague to join us in Galway. The position is in Biochemistry and if research focus lines up we hope the successful person will join us in the Centre for Chromosome biology (chromosome.ie). Reach out if you are interested in applying!
tinyurl.com/2jy4rj3r
tinyurl.com/2jy4rj3r
Reposted by Ben Carty
Just returned from an incredible 3-day multi-lab retreat with the teams of Daniele Fachinetti, Nick @naltemose.bsky.social, and Dominika Gruszka in Pêra, Portugal. Sunshine😎, great company 🤗 and fantastic centromere and chromatin science 🔬! Thanks to all the teams for this wonderful gathering!
May 17, 2026 at 4:28 PM
Just returned from an incredible 3-day multi-lab retreat with the teams of Daniele Fachinetti, Nick @naltemose.bsky.social, and Dominika Gruszka in Pêra, Portugal. Sunshine😎, great company 🤗 and fantastic centromere and chromatin science 🔬! Thanks to all the teams for this wonderful gathering!
Reposted by Ben Carty
Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.
April 20, 2026 at 6:48 AM
Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.
Reposted by Ben Carty
Do you want to move to Oxford and join our lab? There is a computational biologist position open atm to develop and implement tools to analyse TE expression in single cell long read data and more. Apply! #TEsky #UniversityofOxford #postdoc
We are looking for a Postdoc to join our lab at @oxfordbiochemistry.bsky.social. This is a dry-lab focused post on the computational analysis of long read single-cell sequencing data to understand the role of transposable elements (TEs) in early development. my.corehr.com/pls/uoxrecru... #TEsky
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
March 27, 2026 at 12:20 PM
Do you want to move to Oxford and join our lab? There is a computational biologist position open atm to develop and implement tools to analyse TE expression in single cell long read data and more. Apply! #TEsky #UniversityofOxford #postdoc
Reposted by Ben Carty
Single-molecule peptide sequencing through reverse translation of peptides into DNA | Nature Biotechnology https://www.nature.com/articles/s41587-026-03061-z
Single-molecule peptide sequencing through reverse translation of peptides into DNA - Nature Biotechnology
Peptides are sequenced by converting each amino acid into amplifiable DNA barcodes.
www.nature.com
March 19, 2026 at 12:32 AM
Single-molecule peptide sequencing through reverse translation of peptides into DNA | Nature Biotechnology https://www.nature.com/articles/s41587-026-03061-z
Reposted by Ben Carty
Our paper is now out in Nature:
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
1/14
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
1/14
Ancient co-option of LTR retrotransposons as yeast centromeres - Nature
Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...
www.nature.com
February 18, 2026 at 4:03 PM
Our paper is now out in Nature:
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
1/14
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
1/14
Reposted by Ben Carty
🚨 Want to do a #Phd using high-throughput mutagenesis and CRISPR screens to understand how gene body methylation impacts transcription in collaboration with Greg Kudla's group? Do apply, deadline in a week! www.findaphd.com/phds/project...
Deadline 15th December 2025
#epigenetics Please share 🙏
Deadline 15th December 2025
#epigenetics Please share 🙏
www.findaphd.com
December 8, 2025 at 9:33 AM
🚨 Want to do a #Phd using high-throughput mutagenesis and CRISPR screens to understand how gene body methylation impacts transcription in collaboration with Greg Kudla's group? Do apply, deadline in a week! www.findaphd.com/phds/project...
Deadline 15th December 2025
#epigenetics Please share 🙏
Deadline 15th December 2025
#epigenetics Please share 🙏
Reposted by Ben Carty
An early Christmas present for those interested in chromatin and transcription! Fantastic work from @au-ho-yu.bsky.social and @aleksszczurek.bsky.social . Thanks to Inge and Michiel for their help. Please repost!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
SET1/MLL complexes control transcription independently of H3K4me3
Histone H3 lysine 4 trimethylation (H3K4me3) at gene promoters is thought to play a central role in gene transcription. H3K4 methylation is deposited by the SET1 (A/B) and MLL (1-4) multi-protein comp...
www.biorxiv.org
December 11, 2025 at 6:09 AM
An early Christmas present for those interested in chromatin and transcription! Fantastic work from @au-ho-yu.bsky.social and @aleksszczurek.bsky.social . Thanks to Inge and Michiel for their help. Please repost!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Ben Carty
Some Friday reading...new review in Open Biology where we discuss how SWI/SNF maintains the chromatin environment around centromeres, building on recent work from ourselves and others. Lots of fun putting this together with @alison-harrod.bsky.social and @thedownslab.bsky.social!
Boundary issues: SWI/SNF shapes chromatin patterns in and around centromeres
Abstract. The SWI/SNF family of chromatin remodelling complexes, comprising BAF, PBAF and ncBAF, is known for their critical roles in regulating chromatin
royalsocietypublishing.org
December 5, 2025 at 10:30 AM
Some Friday reading...new review in Open Biology where we discuss how SWI/SNF maintains the chromatin environment around centromeres, building on recent work from ourselves and others. Lots of fun putting this together with @alison-harrod.bsky.social and @thedownslab.bsky.social!
Very proud to have our latest work now online in
@natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4
www.nature.com/articles/s41...
@natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4
www.nature.com/articles/s41...
Heterochromatin boundaries maintain centromere position, size and number - Nature Structural & Molecular Biology
Carty et al. identify the H3K9 methyltransferases that restrict the size and position of the centromere protein A chromatin domain, maintaining functional centromeres.
www.nature.com
November 27, 2025 at 9:58 PM
Very proud to have our latest work now online in
@natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4
www.nature.com/articles/s41...
@natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4
www.nature.com/articles/s41...
Reposted by Ben Carty
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 25, 2025 at 12:16 PM
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ben Carty
Very happy to see our paper published online natcomms.nature.com. Thank you to @wellcometrust.bsky.social for funding this work during my time with @robklose.bsky.social and David Booth! Thanks also to collaborators @garcialabms.bsky.social @alexdemendoza.bsky.social and the other authors!
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating cell type-specific genes and transposable elements in choanoflagellates
Nature Communications - Here, the authors investigate chromatin-based gene regulation in the closest relative of animal, choanoflagellates. They uncover a putative dual role for the histone...
rdcu.be
October 29, 2025 at 1:40 PM
Very happy to see our paper published online natcomms.nature.com. Thank you to @wellcometrust.bsky.social for funding this work during my time with @robklose.bsky.social and David Booth! Thanks also to collaborators @garcialabms.bsky.social @alexdemendoza.bsky.social and the other authors!
A fantastic review of the cell cycle control of centromeres from our lab. Lots learned and many open questions 40 years later!
The discovery of CENP-A, the centromere-specific histone H3 variant turns 40 years!
Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out.
link.springer.com/article/10.1...
Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out.
link.springer.com/article/10.1...
July 29, 2025 at 7:42 PM
A fantastic review of the cell cycle control of centromeres from our lab. Lots learned and many open questions 40 years later!
Reposted by Ben Carty
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org
June 20, 2025 at 1:24 PM
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org