Burstein lab
bursteinlab.bsky.social
Burstein lab
@bursteinlab.bsky.social
Having fun with microbial genomics and machine learning
So many bacterial genomes are being edited… Could we spot them in the wild even without obvious markers??? Worry not! Our @EdanGabay has you covered. In our new preprint, she pinpoints such genes disrupting the natural genomic "grammar": www.biorxiv.org/content/10.6... 1/4
September 24, 2026 at 4:56 AM
It annoyed us that annotation tools aren't great at saying "I just don't know". That's a real problem for metagenomes and non-model organisms, where it usually means picking some threshold and hoping for the best. We built FAMUS to try and fix this. doi.org/10.64898/202... 1/8
FAMUS: A Few-Shot Learning Framework for Large-Scale Protein Annotation
Predicting gene function is a pivotal and challenging step in genomic and metagenomic data analysis. Current automatic annotation tools typically rely on the single most similar sequence from the quer...
doi.org
July 12, 2026 at 7:45 AM
Now available in bioinformatics!
Congrats Ella 🎉
🧬 New preprint alert!
Protein language models have transformed biology - but what about the tokens they read?
In our new preprint, 👑@EllaRannon👑 studies how tokenization choices shape pLM performance and efficiency. 🧵 (1/5)
www.biorxiv.org/content/10.6...
www.biorxiv.org
July 9, 2026 at 9:56 AM
Reposted by Burstein lab
🧬 New preprint alert!
Protein language models have transformed biology - but what about the tokens they read?
In our new preprint, 👑@EllaRannon👑 studies how tokenization choices shape pLM performance and efficiency. 🧵 (1/5)
www.biorxiv.org/content/10.6...
www.biorxiv.org
February 16, 2026 at 3:00 AM
Reposted by Burstein lab
How do you kill a MRSA superbug armed with 15 different anti-phage defense systems? You make a smarter phage. Check out our latest preprint on overcoming bacterial immunity using defense-guided engineering to build durable therapeutic phage cocktails! Led by Sarah Voss. doi.org/10.64898/202...
March 27, 2026 at 6:08 PM
🧬 New preprint alert!
Protein language models have transformed biology - but what about the tokens they read?
In our new preprint, 👑@EllaRannon👑 studies how tokenization choices shape pLM performance and efficiency. 🧵 (1/5)
www.biorxiv.org/content/10.6...
www.biorxiv.org
February 16, 2026 at 3:00 AM
1/4 Ever wanted to predict bacterial protein-protein interactions (PPI) on a large scale?
We wanted to, but realized there’s no such algorithm that is both rapid and optimized for bacterial protein analysis.
This led our ⭐️Chen Agassy⭐️ to develop B-PPI: doi.org/10.64898/202...
January 7, 2026 at 9:15 AM
1/6 🧬📊 Curious about the buzz around NLP in biology? Feeling overwhelmed by the rapid developments? We've got you covered! Our review on NLP applications in genomics, by the wonderful Ella Rannon, is now out as a pre-print! #NLP #Bioinformatics arxiv.org/abs/2506.02212
June 7, 2025 at 12:47 PM
Hello Bluesky! Burstein lab just joined - are we too late for the party 👀 ??
June 7, 2025 at 12:40 PM