Chalystha Lee
@chalysthalee.bsky.social
🇲🇾 in 🇦🇺, and now 🇺🇸🗽 | postdoc @ nyu | Interested in how the brain in our gut works!
👩🏻🔬 @margolislabnyu.bsky.social
👩🏻🔬 @margolislabnyu.bsky.social
Reposted by Chalystha Lee
Great to have Dr. Ishmail Abdus-Saboor visit the PRC today! It was exciting to hear about his work on the skin-brain axis and to spend the day talking science. Thank you @ishmailsaboor.bsky.social!
September 16, 2026 at 7:21 PM
Great to have Dr. Ishmail Abdus-Saboor visit the PRC today! It was exciting to hear about his work on the skin-brain axis and to spend the day talking science. Thank you @ishmailsaboor.bsky.social!
Reposted by Chalystha Lee
🎉 Beyond proud to celebrate Dr. Margolis in receiving the ANMS Distinguished Investigator Award for Women in Neurogastroenterology! 🏆
A well-deserved honor celebrating her groundbreaking research and incredible mentorship! 💙
@karapedsgastrodoc.bsky.social
@nyupainresearch.bsky.social
A well-deserved honor celebrating her groundbreaking research and incredible mentorship! 💙
@karapedsgastrodoc.bsky.social
@nyupainresearch.bsky.social
August 11, 2026 at 7:49 PM
🎉 Beyond proud to celebrate Dr. Margolis in receiving the ANMS Distinguished Investigator Award for Women in Neurogastroenterology! 🏆
A well-deserved honor celebrating her groundbreaking research and incredible mentorship! 💙
@karapedsgastrodoc.bsky.social
@nyupainresearch.bsky.social
A well-deserved honor celebrating her groundbreaking research and incredible mentorship! 💙
@karapedsgastrodoc.bsky.social
@nyupainresearch.bsky.social
Reposted by Chalystha Lee
NEW PRC PAPER 🚨: The Jensen lab discovered that the human itch receptor MrGPRX1 traffics to the endosomal network, where it continues to signal and drive TRPV1 sensitization. Congratulations to first author @pazduran.bsky.social and the whole team!
www.frontiersin.org/journals/mol...
www.frontiersin.org/journals/mol...
Frontiers | Endosomal MrGPRX1 signaling sensitizes TRPV1 to enhance itch
G protein-coupled receptors (GPCRs) and TRPV (transient receptor potential vanilloid) channels are crucial for signal transduction in physiological processes...
www.frontiersin.org
July 9, 2026 at 6:09 PM
NEW PRC PAPER 🚨: The Jensen lab discovered that the human itch receptor MrGPRX1 traffics to the endosomal network, where it continues to signal and drive TRPV1 sensitization. Congratulations to first author @pazduran.bsky.social and the whole team!
www.frontiersin.org/journals/mol...
www.frontiersin.org/journals/mol...
Reposted by Chalystha Lee
🎉 Congratulations to Chalystha and Rahi from the Margolis Lab on their achievements at the 2026 Annual Molecular Pathobiology Innovative Research Symposium (AMPIRS)!
Chalystha won 3rd Place for her 3-minute flash talk
Rahi won 3rd Place for her poster presentation
@karapedsgastrodoc.bsky.social
Chalystha won 3rd Place for her 3-minute flash talk
Rahi won 3rd Place for her poster presentation
@karapedsgastrodoc.bsky.social
June 17, 2026 at 8:16 PM
🎉 Congratulations to Chalystha and Rahi from the Margolis Lab on their achievements at the 2026 Annual Molecular Pathobiology Innovative Research Symposium (AMPIRS)!
Chalystha won 3rd Place for her 3-minute flash talk
Rahi won 3rd Place for her poster presentation
@karapedsgastrodoc.bsky.social
Chalystha won 3rd Place for her 3-minute flash talk
Rahi won 3rd Place for her poster presentation
@karapedsgastrodoc.bsky.social
Reposted by Chalystha Lee
NEW PRC PAPER 🚨 from Nestor Jimenez-Vargas and the Bunnett Lab reveals how elevated proteases and histamine drive IBS visceral pain, showing that a prolonged intracellular PAR2 receptor signaling loop keeps the H1 receptor active to continuously amplify and maintain pain. gut.bmj.com/content/earl...
June 17, 2026 at 6:43 PM
NEW PRC PAPER 🚨 from Nestor Jimenez-Vargas and the Bunnett Lab reveals how elevated proteases and histamine drive IBS visceral pain, showing that a prolonged intracellular PAR2 receptor signaling loop keeps the H1 receptor active to continuously amplify and maintain pain. gut.bmj.com/content/earl...
Reposted by Chalystha Lee
Come work with us! We're looking for a new lab manager to help us develop new motion capture methods, new biosensors, and to hopefully learn something cool about the brain. Bonus: you get to do all this in the ATL and, in my humble opinion, we're nice people to work with! markolab.org/careers/
June 16, 2026 at 12:31 PM
Come work with us! We're looking for a new lab manager to help us develop new motion capture methods, new biosensors, and to hopefully learn something cool about the brain. Bonus: you get to do all this in the ATL and, in my humble opinion, we're nice people to work with! markolab.org/careers/
Reposted by Chalystha Lee
Very proud to share this @usasp.bsky.social podcast episode featuring PRC postdoc Elisa Damo @elisadamo.bsky.social, one of the Top 5 Travel Awardees from the USASP Annual Scientific Meeting! @karapedsgastrodoc.bsky.social
soundcloud.com/usasp/episod...
soundcloud.com/usasp/episod...
34. 2026 USASP Annual Meeting Top 5 Trainee Travel Awardees
Listen to the top five travel awardees from the 2026 USASP Annual Meeting which took place from March 23-26, 2026 in Philadelphia, Pennsylvania.
In this episode, we will learn on the current work fro
soundcloud.com
May 8, 2026 at 7:46 PM
Very proud to share this @usasp.bsky.social podcast episode featuring PRC postdoc Elisa Damo @elisadamo.bsky.social, one of the Top 5 Travel Awardees from the USASP Annual Scientific Meeting! @karapedsgastrodoc.bsky.social
soundcloud.com/usasp/episod...
soundcloud.com/usasp/episod...
Reposted by Chalystha Lee
We are thrilled to bring together the NYU pain research community at our symposium tomorrow! Looking forward to a day of exciting science, connection, and collaboration.
May 27, 2026 at 8:38 PM
We are thrilled to bring together the NYU pain research community at our symposium tomorrow! Looking forward to a day of exciting science, connection, and collaboration.
Reposted by Chalystha Lee
Amazing day so far at the PRC symposium! So much exciting science from our research community and awesome keynote speakers. @karapedsgastrodoc.bsky.social @jimr-1.bsky.social @sarahanajjar.bsky.social @tonelloraquel.bsky.social @elisadamo.bsky.social @pazduran.bsky.social @badrsokrat.bsky.social
May 28, 2026 at 7:29 PM
Amazing day so far at the PRC symposium! So much exciting science from our research community and awesome keynote speakers. @karapedsgastrodoc.bsky.social @jimr-1.bsky.social @sarahanajjar.bsky.social @tonelloraquel.bsky.social @elisadamo.bsky.social @pazduran.bsky.social @badrsokrat.bsky.social
Reposted by Chalystha Lee
More shots from our PRC Symposium yesterday. We were grateful to host wonderful keynote speakers: Dr. Walter Koroshetz, Dr. Lin Chang, Dr. Jeffrey Hubbell, and Dr. Ru-Rong Ji! @karapedsgastrodoc.bsky.social
May 29, 2026 at 4:20 PM
More shots from our PRC Symposium yesterday. We were grateful to host wonderful keynote speakers: Dr. Walter Koroshetz, Dr. Lin Chang, Dr. Jeffrey Hubbell, and Dr. Ru-Rong Ji! @karapedsgastrodoc.bsky.social
Congratulations, Mariam!!! Such a pleasure having you in the lab!
ConGRADulations, Mariam! 🎓
It has been a pleasure having Mariam in the Margolis Lab through NYU Dentistry's TRIP&ICE program.
We are so proud of all she has accomplished and wish her the very best in her next chapter!
@karapedsgastrodoc.bsky.social @chalysthalee.bsky.social
It has been a pleasure having Mariam in the Margolis Lab through NYU Dentistry's TRIP&ICE program.
We are so proud of all she has accomplished and wish her the very best in her next chapter!
@karapedsgastrodoc.bsky.social @chalysthalee.bsky.social
May 29, 2026 at 7:39 PM
Congratulations, Mariam!!! Such a pleasure having you in the lab!
Reposted by Chalystha Lee
Highlights from the 2026 Pain Research Center Symposium!
Dr. Kara Margolis presented:
“Compartmental Serotonergic Signaling in Gut–Brain Health: Clinical Implications for Mood and Abdominal Pain”
Thanks to everyone for a great day of science!
@karapedsgastrodoc.bsky.social
Dr. Kara Margolis presented:
“Compartmental Serotonergic Signaling in Gut–Brain Health: Clinical Implications for Mood and Abdominal Pain”
Thanks to everyone for a great day of science!
@karapedsgastrodoc.bsky.social
May 29, 2026 at 7:13 PM
Highlights from the 2026 Pain Research Center Symposium!
Dr. Kara Margolis presented:
“Compartmental Serotonergic Signaling in Gut–Brain Health: Clinical Implications for Mood and Abdominal Pain”
Thanks to everyone for a great day of science!
@karapedsgastrodoc.bsky.social
Dr. Kara Margolis presented:
“Compartmental Serotonergic Signaling in Gut–Brain Health: Clinical Implications for Mood and Abdominal Pain”
Thanks to everyone for a great day of science!
@karapedsgastrodoc.bsky.social
Reposted by Chalystha Lee
The Margolis Lab was proud to be represented by six poster presenters at the 2026 Pain Research Center Symposium! Congratulations to:
Sarah, Daniel, Chalystha, Lin, Rahi, Taeseon
Great job to everyone who presented and contributed to a fantastic day of science!
@karapedsgastrodoc.bsky.social
Sarah, Daniel, Chalystha, Lin, Rahi, Taeseon
Great job to everyone who presented and contributed to a fantastic day of science!
@karapedsgastrodoc.bsky.social
May 29, 2026 at 7:14 PM
The Margolis Lab was proud to be represented by six poster presenters at the 2026 Pain Research Center Symposium! Congratulations to:
Sarah, Daniel, Chalystha, Lin, Rahi, Taeseon
Great job to everyone who presented and contributed to a fantastic day of science!
@karapedsgastrodoc.bsky.social
Sarah, Daniel, Chalystha, Lin, Rahi, Taeseon
Great job to everyone who presented and contributed to a fantastic day of science!
@karapedsgastrodoc.bsky.social
Reposted by Chalystha Lee
More highlights from our amazing team at the NYU Pain Research Center Symposium!
We're proud of our team's contributions and grateful for a fantastic day of science, collaboration, and discovery.
We're proud of our team's contributions and grateful for a fantastic day of science, collaboration, and discovery.
May 29, 2026 at 7:15 PM
More highlights from our amazing team at the NYU Pain Research Center Symposium!
We're proud of our team's contributions and grateful for a fantastic day of science, collaboration, and discovery.
We're proud of our team's contributions and grateful for a fantastic day of science, collaboration, and discovery.
Congratulations Haoming!!!
Congratulations to Haoming on graduating from New York University with a Master of Science in Biology from the Graduate School of Arts and Sciences! 🎓✨
Wishing you all the best in your next chapter, we’re so proud of you!
@karapedsgastrodoc.bsky.social
Wishing you all the best in your next chapter, we’re so proud of you!
@karapedsgastrodoc.bsky.social
May 22, 2026 at 9:38 PM
Congratulations Haoming!!!
Reposted by Chalystha Lee
We've known the gut-brain axis is a key underpinning of Parkinson's disease. Today, for the 1st time, a gut microbiome signature denoting risk found in healthy individuals with genetic predisposition
nature.com/articles/s41...
nature.com/articles/s41...
Microbiome signature of Parkinson’s disease in healthy and genetically at-risk individuals - Nature Medicine
Microbiome analysis suggests that gut microbial changes in Parkinson’s disease evolve progressively from healthy individuals to genetically at-risk individuals to clinically affected patients, with th...
nature.com
April 20, 2026 at 4:04 PM
We've known the gut-brain axis is a key underpinning of Parkinson's disease. Today, for the 1st time, a gut microbiome signature denoting risk found in healthy individuals with genetic predisposition
nature.com/articles/s41...
nature.com/articles/s41...
Reposted by Chalystha Lee
In our latest study, we explore how early experiences can shape gut function and pain later in life.
Dr. @sarahanajjar.bsky.social breaks it down 👇
Dr. @sarahanajjar.bsky.social breaks it down 👇
April 2, 2026 at 6:34 PM
In our latest study, we explore how early experiences can shape gut function and pain later in life.
Dr. @sarahanajjar.bsky.social breaks it down 👇
Dr. @sarahanajjar.bsky.social breaks it down 👇
Well deserved, @linyhung.bsky.social!!!!! 🥳🥳🥳
Dr. Lin Hung from our lab received the 2026 American Gastroenterological Association Research Scholar Award for her project on linking GI-derived oxytocin and serotonin to treat DGBI pain. This prestigious award supports early-career researchers pursuing independent careers in digestive diseases.
April 2, 2026 at 2:41 PM
Well deserved, @linyhung.bsky.social!!!!! 🥳🥳🥳
Look who stopped by NYC from across the globe! Felt like worlds colliding having my PhD PI @elimelb.bsky.social and postdoc PI @karapedsgastrodoc.bsky.social in the same room. So fitting on Intl Day of Women&Girls in Science to celebrate two brilliant women who paved the way for me!
February 11, 2026 at 11:34 PM
Look who stopped by NYC from across the globe! Felt like worlds colliding having my PhD PI @elimelb.bsky.social and postdoc PI @karapedsgastrodoc.bsky.social in the same room. So fitting on Intl Day of Women&Girls in Science to celebrate two brilliant women who paved the way for me!
Reposted by Chalystha Lee
Happy holidays from the Margolis lab! Pic after a hard core karaoke party😂
December 16, 2025 at 2:17 PM
Happy holidays from the Margolis lab! Pic after a hard core karaoke party😂
Reposted by Chalystha Lee
👉 We generated a starter pack for #neurogastroenterology and enteric #neuroscience!
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
November 1, 2025 at 6:37 PM
👉 We generated a starter pack for #neurogastroenterology and enteric #neuroscience!
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Reposted by Chalystha Lee
PRC Highlight: #MargolisLab making strides again! Congrats to Chalystha Lee who received the 2025 ISSR Travel Award at the #ISSR2025 hosted in Vienna! With mentorship from Dr. Kara Margolis & Dr. Michael Gershon lighting the way. #mentorship #ISSR #womeninresearch @chalysthalee.bsky.social
September 10, 2025 at 8:43 PM
PRC Highlight: #MargolisLab making strides again! Congrats to Chalystha Lee who received the 2025 ISSR Travel Award at the #ISSR2025 hosted in Vienna! With mentorship from Dr. Kara Margolis & Dr. Michael Gershon lighting the way. #mentorship #ISSR #womeninresearch @chalysthalee.bsky.social
Reposted by Chalystha Lee
Gabapentin is widely prescribed for nerve pain, but it doesn’t work the same for everyone.
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
August 7, 2025 at 5:27 PM
Gabapentin is widely prescribed for nerve pain, but it doesn’t work the same for everyone.
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
Just back from a great week in Vienna for #ISSR2025. I am grateful for the travel award and the opportunity to share my work. Big thanks to @karapedsgastrodoc.bsky.social and Mike Gershon for their steady support in the lab and my career. Loved connecting with 5-HT researchers from around the world!
July 15, 2025 at 3:34 PM
Just back from a great week in Vienna for #ISSR2025. I am grateful for the travel award and the opportunity to share my work. Big thanks to @karapedsgastrodoc.bsky.social and Mike Gershon for their steady support in the lab and my career. Loved connecting with 5-HT researchers from around the world!