Drugs for Neglected Diseases initiative (DNDi)
@dndi.org
International non-profit developing safe, effective, and affordable treatments for the most neglected patients.
🔬 212 R&D and access partner institutions in 47 countries
🧪 41 clinical trial sites in 16 countries
🔎 To learn more about our activities: dndi.org/about/annual...
🧪 41 clinical trial sites in 16 countries
🔎 To learn more about our activities: dndi.org/about/annual...
September 11, 2026 at 8:56 AM
🔬 212 R&D and access partner institutions in 47 countries
🧪 41 clinical trial sites in 16 countries
🔎 To learn more about our activities: dndi.org/about/annual...
🧪 41 clinical trial sites in 16 countries
🔎 To learn more about our activities: dndi.org/about/annual...
Can oxfendazole help eliminate lymphatic filariasis? This Phase IIa proof‑of‑concept trial published in @springernature.com will evaluate its safety & ability to target adult filarial worms, helping guide development of new treatments. link.springer.com/article/10.1...
A Phase IIa, Proof-of-Concept, Placebo-Controlled, Randomised Trial to Investigate the Efficacy and Safety of Oxfendazole as a Macrofilaricidal Drug in Adults Harbouring Lymphatic Filarial Worms - Inf...
Introduction Lymphatic filariasis (LF) remains a significant public health concern, with India contributing nearly 55% of the global disease burden and placing approximately 487 million people at risk...
link.springer.com
September 9, 2026 at 2:47 PM
Can oxfendazole help eliminate lymphatic filariasis? This Phase IIa proof‑of‑concept trial published in @springernature.com will evaluate its safety & ability to target adult filarial worms, helping guide development of new treatments. link.springer.com/article/10.1...
Finding new treatments for #Chagas disease starts with better tools. This study developed a high‑throughput screening assay for T. cruzi & identified promising compounds that block protein synthesis, opening new avenues for drug discovery. @IJPara www.sciencedirect.com/science/arti...
www.sciencedirect.com
September 9, 2026 at 2:46 PM
Finding new treatments for #Chagas disease starts with better tools. This study developed a high‑throughput screening assay for T. cruzi & identified promising compounds that block protein synthesis, opening new avenues for drug discovery. @IJPara www.sciencedirect.com/science/arti...
As part of the 2025–26 #WithoutBordersMediaFellowship, journalist Rituparna Palit, a recipient of the MSF SouthAsia-DNDi Grant on #NTDs, explores #mycetoma in her latest feature for The Scientist:
www.the-scientist.com/mycetoma-the...
www.the-scientist.com/mycetoma-the...
Mycetoma: The Invisible Disease Beneath India's Soil | The Scientist
Years of wrong treatments, changing risk factors, and missing registries leave patients fighting a losing battle against a disabling disease.
www.the-scientist.com
September 7, 2026 at 10:30 AM
As part of the 2025–26 #WithoutBordersMediaFellowship, journalist Rituparna Palit, a recipient of the MSF SouthAsia-DNDi Grant on #NTDs, explores #mycetoma in her latest feature for The Scientist:
www.the-scientist.com/mycetoma-the...
www.the-scientist.com/mycetoma-the...
For the first time, dengue mosquitoes have been found breeding in London.
As our climate warms, invasive mosquitoes are increasingly being detected in new areas. But despite this growing global threat, there is still no treatment for dengue.
@bbcnewsunofficial.bsky.social www.bbc.com/news/article...
As our climate warms, invasive mosquitoes are increasingly being detected in new areas. But despite this growing global threat, there is still no treatment for dengue.
@bbcnewsunofficial.bsky.social www.bbc.com/news/article...
September 4, 2026 at 12:25 PM
For the first time, dengue mosquitoes have been found breeding in London.
As our climate warms, invasive mosquitoes are increasingly being detected in new areas. But despite this growing global threat, there is still no treatment for dengue.
@bbcnewsunofficial.bsky.social www.bbc.com/news/article...
As our climate warms, invasive mosquitoes are increasingly being detected in new areas. But despite this growing global threat, there is still no treatment for dengue.
@bbcnewsunofficial.bsky.social www.bbc.com/news/article...
Reposted by Drugs for Neglected Diseases initiative (DNDi)
📅 9 Sept | 15:00-17:00 CEST
📍 @europarl.europa.eu& online
How can public investment in health R&D deliver greater public benefit? Join MPP, @dndi.org & @saludporderecho.bsky.social to explore how access planning can help make publicly funded research more accessible and affordable.
🔗 bit.ly/3VbYRdS
📍 @europarl.europa.eu& online
How can public investment in health R&D deliver greater public benefit? Join MPP, @dndi.org & @saludporderecho.bsky.social to explore how access planning can help make publicly funded research more accessible and affordable.
🔗 bit.ly/3VbYRdS
September 4, 2026 at 10:46 AM
📅 9 Sept | 15:00-17:00 CEST
📍 @europarl.europa.eu& online
How can public investment in health R&D deliver greater public benefit? Join MPP, @dndi.org & @saludporderecho.bsky.social to explore how access planning can help make publicly funded research more accessible and affordable.
🔗 bit.ly/3VbYRdS
📍 @europarl.europa.eu& online
How can public investment in health R&D deliver greater public benefit? Join MPP, @dndi.org & @saludporderecho.bsky.social to explore how access planning can help make publicly funded research more accessible and affordable.
🔗 bit.ly/3VbYRdS
Our Asia Continental Lead, Sanjay Sarin, shares his perspectives with BioSpectrum Asia on the future of #NTD research in Asia, the rising burden of dengue, and the partnerships needed to accelerate the development of affordable, accessible treatments: www.biospectrumasia.com/opinion/29/2...
“Dengue will remain a major regional priority as we work with partners to expand treatment options across Asia”
“Dengue will remain a major regional priority as we work with partners to expand treatment options across Asia”
www.biospectrumasia.com
September 3, 2026 at 10:27 AM
Our Asia Continental Lead, Sanjay Sarin, shares his perspectives with BioSpectrum Asia on the future of #NTD research in Asia, the rising burden of dengue, and the partnerships needed to accelerate the development of affordable, accessible treatments: www.biospectrumasia.com/opinion/29/2...
Join us for a discussion on the growing practice of Access Planning in R&D, examining how it can help ensure that publicly funded R&D translates into timely public health-driven innovation and accessible, affordable, and available resulting health technologies.
docs.google.com/forms/d/e/1F...
docs.google.com/forms/d/e/1F...
September 3, 2026 at 9:25 AM
Join us for a discussion on the growing practice of Access Planning in R&D, examining how it can help ensure that publicly funded R&D translates into timely public health-driven innovation and accessible, affordable, and available resulting health technologies.
docs.google.com/forms/d/e/1F...
docs.google.com/forms/d/e/1F...
Reposted by Drugs for Neglected Diseases initiative (DNDi)
Why do women remain underrepresented in clinical trials & how do we address the gaps?
Join @dndi.org & IQVIA for a hybrid Media Science Café on gender-responsive R&D.
🗓️ Friday, 4th September, 2026
⏲️ 11:00-13:00 EAT
🔗 Register here bit.ly/4cnjWIl
#WomensHealth #HealthforAll
Join @dndi.org & IQVIA for a hybrid Media Science Café on gender-responsive R&D.
🗓️ Friday, 4th September, 2026
⏲️ 11:00-13:00 EAT
🔗 Register here bit.ly/4cnjWIl
#WomensHealth #HealthforAll
Welcome! You are invited to join a webinar: IQVIA-DNDi Media Science Cafe. After registering, you will receive a confirmation email about joining the webinar.
IQVIA and Drugs for Neglected Diseases initiative (DNDi) are partnering to host a media science cafe on Friday 4th September, 2026. The event will bring together researchers, regulators, policymakers,...
bit.ly
September 1, 2026 at 2:32 PM
Why do women remain underrepresented in clinical trials & how do we address the gaps?
Join @dndi.org & IQVIA for a hybrid Media Science Café on gender-responsive R&D.
🗓️ Friday, 4th September, 2026
⏲️ 11:00-13:00 EAT
🔗 Register here bit.ly/4cnjWIl
#WomensHealth #HealthforAll
Join @dndi.org & IQVIA for a hybrid Media Science Café on gender-responsive R&D.
🗓️ Friday, 4th September, 2026
⏲️ 11:00-13:00 EAT
🔗 Register here bit.ly/4cnjWIl
#WomensHealth #HealthforAll
New in @jamanetworkopen.com: Phase 2 results for Dengue-mAb show the first proof of concept for an antiviral as a treatment for confirmed dengue patients seeking medical care. At 5–7mg/kg, it rapidly cut viremia and fever, with no related serious AEs.
📄 Study: jamanetwork.com/journals/jam...
1/2
📄 Study: jamanetwork.com/journals/jam...
1/2
Safety and Preliminary Efficacy of Dengue Monoclonal Antibody in Adult Patients
This randomized clinical trial examines dengue monoclonal antibody (Dengue-mAb) as a potential therapeutic option for adults infected with dengue virus in India.
jamanetwork.com
August 27, 2026 at 1:36 PM
New in @jamanetworkopen.com: Phase 2 results for Dengue-mAb show the first proof of concept for an antiviral as a treatment for confirmed dengue patients seeking medical care. At 5–7mg/kg, it rapidly cut viremia and fever, with no related serious AEs.
📄 Study: jamanetwork.com/journals/jam...
1/2
📄 Study: jamanetwork.com/journals/jam...
1/2
How to unlock the power of crowdsourced science to prepare for future coronavirus pandemics?
Read our latest Drug Discovery Explained story on the
@covid-moonshot.bsky.social and @asapdiscovery.bsky.social #openscience initiatives:
🔗 stories.dndi.org/drug-discove...
#pandemicpreparedness
Read our latest Drug Discovery Explained story on the
@covid-moonshot.bsky.social and @asapdiscovery.bsky.social #openscience initiatives:
🔗 stories.dndi.org/drug-discove...
#pandemicpreparedness
August 27, 2026 at 9:49 AM
How to unlock the power of crowdsourced science to prepare for future coronavirus pandemics?
Read our latest Drug Discovery Explained story on the
@covid-moonshot.bsky.social and @asapdiscovery.bsky.social #openscience initiatives:
🔗 stories.dndi.org/drug-discove...
#pandemicpreparedness
Read our latest Drug Discovery Explained story on the
@covid-moonshot.bsky.social and @asapdiscovery.bsky.social #openscience initiatives:
🔗 stories.dndi.org/drug-discove...
#pandemicpreparedness
swissinfo.ch takes a closer look at the strategic collaboration between DNDi, @mmv.org and @gardp.bsky.social as the global health landscape changes.
🔗Read here: www.swissinfo.ch/eng/new-trea...
🔗Read here: www.swissinfo.ch/eng/new-trea...
Swiss non-profit drugmakers team up as funding shrinks
As global health funding dries up and Big Pharma chases profits, who is left to develop lifesaving drugs for the world’s most neglected patients?
www.swissinfo.ch
August 26, 2026 at 9:31 AM
swissinfo.ch takes a closer look at the strategic collaboration between DNDi, @mmv.org and @gardp.bsky.social as the global health landscape changes.
🔗Read here: www.swissinfo.ch/eng/new-trea...
🔗Read here: www.swissinfo.ch/eng/new-trea...
We are proud to contribute to a new publication in the Journal of Translational Medicine on ICH E21 - guidance to improve the inclusion of pregnant and breastfeeding individuals in clinical trials and address evidence gaps in their care.
link.springer.com/epdf/10.1186...
link.springer.com/epdf/10.1186...
August 26, 2026 at 7:56 AM
We are proud to contribute to a new publication in the Journal of Translational Medicine on ICH E21 - guidance to improve the inclusion of pregnant and breastfeeding individuals in clinical trials and address evidence gaps in their care.
link.springer.com/epdf/10.1186...
link.springer.com/epdf/10.1186...
Ten years ago, #mycetoma joined the @who.int list of neglected tropical diseases.
So what has a decade of recognition made possible? And what still hasn't changed?
Our new digital story brings the whole decade together.
dndi.org/stories/2026...
#MycetomaAt10 #BeatNTDs
So what has a decade of recognition made possible? And what still hasn't changed?
Our new digital story brings the whole decade together.
dndi.org/stories/2026...
#MycetomaAt10 #BeatNTDs
Mycetoma at 10: What recognition made possible
2026 marks 10 years since mycetoma was formally recognized as a neglected tropical disease by the World Health Organization (WHO).
dndi.org
August 24, 2026 at 8:55 AM
Ten years ago, #mycetoma joined the @who.int list of neglected tropical diseases.
So what has a decade of recognition made possible? And what still hasn't changed?
Our new digital story brings the whole decade together.
dndi.org/stories/2026...
#MycetomaAt10 #BeatNTDs
So what has a decade of recognition made possible? And what still hasn't changed?
Our new digital story brings the whole decade together.
dndi.org/stories/2026...
#MycetomaAt10 #BeatNTDs
When public money funds pandemic innovations, who benefits?
Article 9.5 of the WHO Pandemic Agreement requires governments to develop policies on how publicly funded R&D can support equitable access to the products that result from it.
Learn more ⤵️
Article 9.5 of the WHO Pandemic Agreement requires governments to develop policies on how publicly funded R&D can support equitable access to the products that result from it.
Learn more ⤵️
August 21, 2026 at 8:12 AM
When public money funds pandemic innovations, who benefits?
Article 9.5 of the WHO Pandemic Agreement requires governments to develop policies on how publicly funded R&D can support equitable access to the products that result from it.
Learn more ⤵️
Article 9.5 of the WHO Pandemic Agreement requires governments to develop policies on how publicly funded R&D can support equitable access to the products that result from it.
Learn more ⤵️
🦟 Kenya is currently experiencing an upsurge in #dengue fever, with cases concentrated in Garissa and Wajir counties and now spreading to the coastal region.
The two counties have recorded several deaths since the outbreak began a couple of months ago.
There is no specific treatment for dengue.
The two counties have recorded several deaths since the outbreak began a couple of months ago.
There is no specific treatment for dengue.
August 19, 2026 at 7:43 AM
🦟 Kenya is currently experiencing an upsurge in #dengue fever, with cases concentrated in Garissa and Wajir counties and now spreading to the coastal region.
The two counties have recorded several deaths since the outbreak began a couple of months ago.
There is no specific treatment for dengue.
The two counties have recorded several deaths since the outbreak began a couple of months ago.
There is no specific treatment for dengue.
Writer Daisy Hernández @dazeher.bsky.social joins our podcast to reflect on how her aunt’s experience with #Chagas disease exposed a wider public health failure affecting millions. We talk about the impact of NTDs, barriers to care, and the power of patient stories.
open.spotify.com/episode/5COi...
open.spotify.com/episode/5COi...
Ep. 4 Daisy Hernandez on Chagas disease
The DNDi podcast · Episode
open.spotify.com
August 12, 2026 at 9:34 AM
Writer Daisy Hernández @dazeher.bsky.social joins our podcast to reflect on how her aunt’s experience with #Chagas disease exposed a wider public health failure affecting millions. We talk about the impact of NTDs, barriers to care, and the power of patient stories.
open.spotify.com/episode/5COi...
open.spotify.com/episode/5COi...
Reposted by Drugs for Neglected Diseases initiative (DNDi)
A new sleeping sickness drug -acoziborole, recently got approved in the DRC. A single dose, 96% effective, developed & trial-tested by African scientists.
This @nature.com op-ed argues this is a glimpse of Africa's growing leadership in medical innovation. @dndi.org
🔗 bit.ly/4giHUGN
This @nature.com op-ed argues this is a glimpse of Africa's growing leadership in medical innovation. @dndi.org
🔗 bit.ly/4giHUGN
A new chapter for African medical innovation
The registration of a new sleeping sickness medicine illustrates how African scientists are helping to reshape every stage of drug development, from discovery to delivery.
nature.com
August 7, 2026 at 2:24 PM
A new sleeping sickness drug -acoziborole, recently got approved in the DRC. A single dose, 96% effective, developed & trial-tested by African scientists.
This @nature.com op-ed argues this is a glimpse of Africa's growing leadership in medical innovation. @dndi.org
🔗 bit.ly/4giHUGN
This @nature.com op-ed argues this is a glimpse of Africa's growing leadership in medical innovation. @dndi.org
🔗 bit.ly/4giHUGN
The issue isn’t only that millions live with #Chagas disease & cutaneous #leishmaniasis. The issue is that science struggles to respond fast enough.
New study shows how collaborative platforms are reshaping research: cooperation, tech transfer & shared governance.
📖 www.scielo.br/j/physis/a/N...
New study shows how collaborative platforms are reshaping research: cooperation, tech transfer & shared governance.
📖 www.scielo.br/j/physis/a/N...
www.scielo.br
July 31, 2026 at 1:34 PM
The issue isn’t only that millions live with #Chagas disease & cutaneous #leishmaniasis. The issue is that science struggles to respond fast enough.
New study shows how collaborative platforms are reshaping research: cooperation, tech transfer & shared governance.
📖 www.scielo.br/j/physis/a/N...
New study shows how collaborative platforms are reshaping research: cooperation, tech transfer & shared governance.
📖 www.scielo.br/j/physis/a/N...
🌍 We’re #hiring!
We are seeking an Executive Director to lead DNDi through our next phase of impact, innovation, & sustainable growth.
📌 Based in Geneva, Switzerland
✅ Full-time position – 100%
📆 Deadline: 15 September 2026
👉 Find out more and apply here: careers-dndi.icims.com/jobs/1246/ex...
We are seeking an Executive Director to lead DNDi through our next phase of impact, innovation, & sustainable growth.
📌 Based in Geneva, Switzerland
✅ Full-time position – 100%
📆 Deadline: 15 September 2026
👉 Find out more and apply here: careers-dndi.icims.com/jobs/1246/ex...
July 31, 2026 at 7:26 AM
🌍 We’re #hiring!
We are seeking an Executive Director to lead DNDi through our next phase of impact, innovation, & sustainable growth.
📌 Based in Geneva, Switzerland
✅ Full-time position – 100%
📆 Deadline: 15 September 2026
👉 Find out more and apply here: careers-dndi.icims.com/jobs/1246/ex...
We are seeking an Executive Director to lead DNDi through our next phase of impact, innovation, & sustainable growth.
📌 Based in Geneva, Switzerland
✅ Full-time position – 100%
📆 Deadline: 15 September 2026
👉 Find out more and apply here: careers-dndi.icims.com/jobs/1246/ex...
Reposted by Drugs for Neglected Diseases initiative (DNDi)
Good news! @WHO recommends new treatment guidelines for #leishmaniasis.
East Africa: new combo treatment is 90%+ effective, cuts injections 34→14, hospitalization 60-90→14 days.
South Asia: safer PKDL options, less toxic.
Read more bit.ly/4x9OYv3 #BeatNTDs @dndi.org
East Africa: new combo treatment is 90%+ effective, cuts injections 34→14, hospitalization 60-90→14 days.
South Asia: safer PKDL options, less toxic.
Read more bit.ly/4x9OYv3 #BeatNTDs @dndi.org
WHO recommends new, better and safer treatment regimens for leishmaniasis
The World Health Organization (WHO) has issued major updates to its leishmaniasis treatment guidelines, introducing a new regimen for visceral leishmaniasis (VL/kala-azar) in eastern Africa and severa...
bit.ly
July 29, 2026 at 8:44 AM
Good news! @WHO recommends new treatment guidelines for #leishmaniasis.
East Africa: new combo treatment is 90%+ effective, cuts injections 34→14, hospitalization 60-90→14 days.
South Asia: safer PKDL options, less toxic.
Read more bit.ly/4x9OYv3 #BeatNTDs @dndi.org
East Africa: new combo treatment is 90%+ effective, cuts injections 34→14, hospitalization 60-90→14 days.
South Asia: safer PKDL options, less toxic.
Read more bit.ly/4x9OYv3 #BeatNTDs @dndi.org
New method for finding drugs for #Chagas disease: www.mdpi.com/1424-8247/19...
By combining chemical similarity & AI protein structure predictions, the tool correctly identified known drug targets in most tests, helping speed up drug discovery while reducing time & cost @mdpiopenaccess.bsky.social
By combining chemical similarity & AI protein structure predictions, the tool correctly identified known drug targets in most tests, helping speed up drug discovery while reducing time & cost @mdpiopenaccess.bsky.social
www.mdpi.com
July 29, 2026 at 10:16 AM
New method for finding drugs for #Chagas disease: www.mdpi.com/1424-8247/19...
By combining chemical similarity & AI protein structure predictions, the tool correctly identified known drug targets in most tests, helping speed up drug discovery while reducing time & cost @mdpiopenaccess.bsky.social
By combining chemical similarity & AI protein structure predictions, the tool correctly identified known drug targets in most tests, helping speed up drug discovery while reducing time & cost @mdpiopenaccess.bsky.social
Dengue is no longer just a tropical disease.
As the climate warms, the dengue-carrying mosquito is expanding its reach to new regions.
Despite this growing global threat, there is still no specific treatment for dengue.
Together with our partners, we're working to change this!
As the climate warms, the dengue-carrying mosquito is expanding its reach to new regions.
Despite this growing global threat, there is still no specific treatment for dengue.
Together with our partners, we're working to change this!
July 24, 2026 at 9:30 AM
Dengue is no longer just a tropical disease.
As the climate warms, the dengue-carrying mosquito is expanding its reach to new regions.
Despite this growing global threat, there is still no specific treatment for dengue.
Together with our partners, we're working to change this!
As the climate warms, the dengue-carrying mosquito is expanding its reach to new regions.
Despite this growing global threat, there is still no specific treatment for dengue.
Together with our partners, we're working to change this!
Reposted by Drugs for Neglected Diseases initiative (DNDi)
What happens when equity becomes negotiable, and solidarity becomes optional?
During the April 2026 Open Forum, Michelle Childs from @dndi.org reflected on what it takes to make solidarity operational.
Watch the excerpt here: www.youtube.com/watch?v=eIe2...
#Health #Solidarity #Bioethics
During the April 2026 Open Forum, Michelle Childs from @dndi.org reflected on what it takes to make solidarity operational.
Watch the excerpt here: www.youtube.com/watch?v=eIe2...
#Health #Solidarity #Bioethics
July 23, 2026 at 7:25 AM
What happens when equity becomes negotiable, and solidarity becomes optional?
During the April 2026 Open Forum, Michelle Childs from @dndi.org reflected on what it takes to make solidarity operational.
Watch the excerpt here: www.youtube.com/watch?v=eIe2...
#Health #Solidarity #Bioethics
During the April 2026 Open Forum, Michelle Childs from @dndi.org reflected on what it takes to make solidarity operational.
Watch the excerpt here: www.youtube.com/watch?v=eIe2...
#Health #Solidarity #Bioethics
Last week, experts came together in a webinar to reflect on the last 10 years of #mycetoma progress and look at future priorities to tackle this devastating disease.
If you missed it, listen to the audio recording here: www.youtube.com/watch?v=scke...
If you missed it, listen to the audio recording here: www.youtube.com/watch?v=scke...
A decade of mycetoma advocacy and research (webinar audio recording)
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
www.youtube.com
July 23, 2026 at 2:16 PM
Last week, experts came together in a webinar to reflect on the last 10 years of #mycetoma progress and look at future priorities to tackle this devastating disease.
If you missed it, listen to the audio recording here: www.youtube.com/watch?v=scke...
If you missed it, listen to the audio recording here: www.youtube.com/watch?v=scke...