Eduardo Villablanca
@ejvillablanca.bsky.social
Mucosal Immunologist interested in the complexity of IBD. Professor @Karolinskainst, Wallenberg Fellow & editor @MucosalImmunol. Opinions are my own
Pinned
Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is a manifestation of an inappropriate inflammatory response to intestinal microorganisms in genetically s...
ki.se
Welcome to our new KI lab webpage!
Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca
ki.se/en/research/...
Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca
ki.se/en/research/...
This is one of the most exciting IBD papers of 2026 so far!!! 👇🏼
Every now and then, a study comes along that fundamentally changes how we think about disease mechanisms. This is one of them.
www.nejm.org/doi/full/10....
Every now and then, a study comes along that fundamentally changes how we think about disease mechanisms. This is one of them.
www.nejm.org/doi/full/10....
Interleukin-10 Autoantibodies and HLA-DRB1*01:03 in Inflammatory Bowel Disease | NEJM
Neutralizing autoantibodies against interleukin-10 can result in a phenocopy of monogenic
defects of interleukin-10 signaling in children and may be associated with inflammatory
bowel disease (IBD)...
www.nejm.org
June 13, 2026 at 7:30 AM
This is one of the most exciting IBD papers of 2026 so far!!! 👇🏼
Every now and then, a study comes along that fundamentally changes how we think about disease mechanisms. This is one of them.
www.nejm.org/doi/full/10....
Every now and then, a study comes along that fundamentally changes how we think about disease mechanisms. This is one of them.
www.nejm.org/doi/full/10....
Reposted by Eduardo Villablanca
Chronic immune diseases are shaped by multiple inflammatory processes happening at once. This is shown in a mouse study from Karolinska Institutet. The findings may help explain why patients respond differently to treatment.
@ki.se @ejvillablanca.bsky.social #immunology
tinyurl.com/5bkn276u
@ki.se @ejvillablanca.bsky.social #immunology
tinyurl.com/5bkn276u
Chronic bowel disease involves multiple types of inflammation happening at once
Chronic immune diseases are shaped by multiple inflammatory processes happening at the same time, each in different parts of the tissue. This is shown in a mouse study from Karolinska Institutet, publ...
tinyurl.com
May 8, 2026 at 7:56 AM
Chronic immune diseases are shaped by multiple inflammatory processes happening at once. This is shown in a mouse study from Karolinska Institutet. The findings may help explain why patients respond differently to treatment.
@ki.se @ejvillablanca.bsky.social #immunology
tinyurl.com/5bkn276u
@ki.se @ejvillablanca.bsky.social #immunology
tinyurl.com/5bkn276u
Reposted by Eduardo Villablanca
Shared inflammatory programs, epithelial antigen presentation, and dynamic neutrophil states link mouse models to human #IBD and highlighting epithelial-immune crosstalk as a therapeutic target @cp-immunity.bsky.social
www.cell.com/immunity/ful... @ki.se @ejvillablanca.bsky.social
www.cell.com/immunity/ful... @ki.se @ejvillablanca.bsky.social
May 6, 2026 at 3:52 PM
Shared inflammatory programs, epithelial antigen presentation, and dynamic neutrophil states link mouse models to human #IBD and highlighting epithelial-immune crosstalk as a therapeutic target @cp-immunity.bsky.social
www.cell.com/immunity/ful... @ki.se @ejvillablanca.bsky.social
www.cell.com/immunity/ful... @ki.se @ejvillablanca.bsky.social
Thanks for the invite to discuss how we can think out of the box to explain mucosal immunology :)
It’s #MucosalMonday and time for another @societymucosalimm.bsky.social podcast episode! Hear from @ejvillablanca.bsky.social, @nevesjf.bsky.social and @diacoman.bsky.social, as they discuss their latest work in MI: www.iheart.com/podcast/269-...
Organismal mucosal immunology - Mucosal Immunology Podcast | iHeart
<p>Join Agnes Garcias Lopez and Marion Brunck as they chat with Dr. Eduardo Villablanca at Karolinska Institutet in Stockholm, Sweden, and apply Game Theory to host-microbe interactions, <a href='http...
www.iheart.com
March 23, 2026 at 4:18 PM
Thanks for the invite to discuss how we can think out of the box to explain mucosal immunology :)
Reposted by Eduardo Villablanca
#ECCO26 Feb 19 Stockholm, Ludwig Erlmeier (UMCG) presents: “High-throughput antibody epitope repertoire profiling links NOD2 risk-variants to specific antibody responses in Crohn’s disease.”
A step toward connecting genetic risk with functional immune signatures in IBD
cm.ecco-ibd.eu/cmPortal/sea...
A step toward connecting genetic risk with functional immune signatures in IBD
cm.ecco-ibd.eu/cmPortal/sea...
February 16, 2026 at 5:16 PM
#ECCO26 Feb 19 Stockholm, Ludwig Erlmeier (UMCG) presents: “High-throughput antibody epitope repertoire profiling links NOD2 risk-variants to specific antibody responses in Crohn’s disease.”
A step toward connecting genetic risk with functional immune signatures in IBD
cm.ecco-ibd.eu/cmPortal/sea...
A step toward connecting genetic risk with functional immune signatures in IBD
cm.ecco-ibd.eu/cmPortal/sea...
Our KAW research grant focuses on uncovering novel drivers of mucosal healing by leveraging unique IBD cohorts and novel technologies to map cell–microbiota interactions, complemented by advanced non-animal models like human organoids
Check the note 👇🏼
kaw.wallenberg.org/en/research/... #Hashtag
Check the note 👇🏼
kaw.wallenberg.org/en/research/... #Hashtag
Promoting healing to cure intestinal autoimmunity | Knut and Alice Wallenberg Foundation
Immunosuppressive drugs are currently the main therapeutic option for treating inflammatory bowel disease (IBD). However, fewer than half of patients achieve sustained benefit, and these treatments ca...
kaw.wallenberg.org
January 9, 2026 at 1:15 AM
Our KAW research grant focuses on uncovering novel drivers of mucosal healing by leveraging unique IBD cohorts and novel technologies to map cell–microbiota interactions, complemented by advanced non-animal models like human organoids
Check the note 👇🏼
kaw.wallenberg.org/en/research/... #Hashtag
Check the note 👇🏼
kaw.wallenberg.org/en/research/... #Hashtag
Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications
@cp-cancercell.bsky.social
www.cell.com/cancer-cell/...
@cp-cancercell.bsky.social
www.cell.com/cancer-cell/...
Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications
Liu et al. review how spatial omics technologies reveal the organization, interaction,
and evolution of tumor cells and their microenvironment within tissues. They highlight
analytical advances that t...
www.cell.com
January 2, 2026 at 3:44 AM
Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications
@cp-cancercell.bsky.social
www.cell.com/cancer-cell/...
@cp-cancercell.bsky.social
www.cell.com/cancer-cell/...
This one resonates a lot!
“I thought science hinged on prestige. Moving abroad made me reassess my priorities”
www.science.org/content/arti...
“I thought science hinged on prestige. Moving abroad made me reassess my priorities”
www.science.org/content/arti...
I thought science hinged on prestige. Moving abroad made me reassess my priorities
In Denmark, this Ph.D. student fell in love with an egalitarian society that values work-life balance
www.science.org
December 26, 2025 at 8:32 PM
This one resonates a lot!
“I thought science hinged on prestige. Moving abroad made me reassess my priorities”
www.science.org/content/arti...
“I thought science hinged on prestige. Moving abroad made me reassess my priorities”
www.science.org/content/arti...
Connecting AI to biology: Model Context Protocol
www.ebi.ac.uk/about/news/p...
www.ebi.ac.uk/about/news/p...
Connecting AI to biology: Model Context Protocol
Julio Saez-Rodriguez discusses how MCP servers are helping AI connect to life science databases, making AI a more reproducible tool for research.
www.ebi.ac.uk
December 23, 2025 at 8:34 AM
Connecting AI to biology: Model Context Protocol
www.ebi.ac.uk/about/news/p...
www.ebi.ac.uk/about/news/p...
Gut microbiota promotes immune tolerance at the maternal-fetal interface
www.cell.com/cell/abstrac...
“our findings identify microbiota-dependent immune tolerance mechanisms that promote fetal development.”
www.cell.com/cell/abstrac...
“our findings identify microbiota-dependent immune tolerance mechanisms that promote fetal development.”
Gut microbiota promotes immune tolerance at the maternal-fetal interface
Microbiota-dependent tryptophan-derived indole deficiency is linked to mouse fetal
resorption and human recurrent miscarriage. Tryptophan-derived indoles prime MDSCs
and RORγt+ Tregs to suppress IFN-γ...
www.cell.com
December 20, 2025 at 7:46 AM
Gut microbiota promotes immune tolerance at the maternal-fetal interface
www.cell.com/cell/abstrac...
“our findings identify microbiota-dependent immune tolerance mechanisms that promote fetal development.”
www.cell.com/cell/abstrac...
“our findings identify microbiota-dependent immune tolerance mechanisms that promote fetal development.”
Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches: Cancer Cell www.cell.com/cancer-cell/...
Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches
Chen et al. identify two distinct antigen-presenting cancer-associated fibroblast
(apCAF) populations across multiple cancer types. Mesothelial-related apCAFs locate
near cancer cells while fibrocyte-...
www.cell.com
December 11, 2025 at 5:33 AM
Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches: Cancer Cell www.cell.com/cancer-cell/...
Human gut M cells resemble dendritic cells and present gluten antigen
@nature.com
www.nature.com/articles/s41...
@nature.com
www.nature.com/articles/s41...
Human gut M cells resemble dendritic cells and present gluten antigen - Nature
An intestinal organoid model recapitulates human microfold (M) cell function and transcriptomic profiling and biochemical assays demonstrate that M cells uptake and present antigens to the immune syst...
www.nature.com
December 11, 2025 at 5:29 AM
Human gut M cells resemble dendritic cells and present gluten antigen
@nature.com
www.nature.com/articles/s41...
@nature.com
www.nature.com/articles/s41...
The dawn of ‘off-the-shelf’ B cell-depleting therapies for autoimmune diseases
@Nature Reviews Rheumatology
www.nature.com/articles/s41...
@Nature Reviews Rheumatology
www.nature.com/articles/s41...
The dawn of ‘off-the-shelf’ B cell-depleting therapies for autoimmune diseases - Nature Reviews Rheumatology
In 2025, a new wave of ‘off-the-shelf’ B cell-depleting modalities for the treatment of autoimmune diseases emerged, encompassing allogeneic cellular therapies, in vivo chimeric antigen receptor engin...
www.nature.com
December 11, 2025 at 5:17 AM
The dawn of ‘off-the-shelf’ B cell-depleting therapies for autoimmune diseases
@Nature Reviews Rheumatology
www.nature.com/articles/s41...
@Nature Reviews Rheumatology
www.nature.com/articles/s41...
Join us ag the upcoming DDLS CMB Conference:
Data Driven Systems Biology – Harnessing Big Data and Systems Approaches to Decode Complex Biology
March 24–25 at LifeCity, Hagastaden, Solna.
#scilifelab #DDLS #datadriven #systemsbiology
Register here! 👇🏼👇👇🏾👇🏿
lnkd.in/dT9gCvEu
Data Driven Systems Biology – Harnessing Big Data and Systems Approaches to Decode Complex Biology
March 24–25 at LifeCity, Hagastaden, Solna.
#scilifelab #DDLS #datadriven #systemsbiology
Register here! 👇🏼👇👇🏾👇🏿
lnkd.in/dT9gCvEu
December 6, 2025 at 8:30 PM
Join us ag the upcoming DDLS CMB Conference:
Data Driven Systems Biology – Harnessing Big Data and Systems Approaches to Decode Complex Biology
March 24–25 at LifeCity, Hagastaden, Solna.
#scilifelab #DDLS #datadriven #systemsbiology
Register here! 👇🏼👇👇🏾👇🏿
lnkd.in/dT9gCvEu
Data Driven Systems Biology – Harnessing Big Data and Systems Approaches to Decode Complex Biology
March 24–25 at LifeCity, Hagastaden, Solna.
#scilifelab #DDLS #datadriven #systemsbiology
Register here! 👇🏼👇👇🏾👇🏿
lnkd.in/dT9gCvEu
What a great #BSI25! The second-largest immunology conference was a fantastic chance to meet old friends and make new ones. Amazing science, and they definitely know how to party 😜
December 4, 2025 at 4:29 PM
What a great #BSI25! The second-largest immunology conference was a fantastic chance to meet old friends and make new ones. Amazing science, and they definitely know how to party 😜
Reposted by Eduardo Villablanca
#BSI25 day 2! Another wonderful day of immunology and a chance to discuss my PhD research during the first poster session. Meeting so many people, discussing cutting-edge immunology and sharing our passions for science! @mrccmm.bsky.social
December 2, 2025 at 10:29 PM
#BSI25 day 2! Another wonderful day of immunology and a chance to discuss my PhD research during the first poster session. Meeting so many people, discussing cutting-edge immunology and sharing our passions for science! @mrccmm.bsky.social
Doctoral (PhD) Position – Spatial Transcriptomics, Bioinformatics & Mucosal Immunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
November 29, 2025 at 4:15 PM
Doctoral (PhD) Position – Spatial Transcriptomics, Bioinformatics & Mucosal Immunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination
PNAS www.pnas.org/doi/10.1073/...
PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
November 28, 2025 at 1:04 PM
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination
PNAS www.pnas.org/doi/10.1073/...
PNAS www.pnas.org/doi/10.1073/...
Reposted by Eduardo Villablanca
Joshua A. Boyce, MD, describes two studies implicating intestinally generated cysteinyl leukotrienes in food anaphylaxis. Learn more: nej.md/4rp7MEL
#MedSky #PedSky #Immunology
#MedSky #PedSky #Immunology
November 22, 2025 at 2:02 PM
Joshua A. Boyce, MD, describes two studies implicating intestinally generated cysteinyl leukotrienes in food anaphylaxis. Learn more: nej.md/4rp7MEL
#MedSky #PedSky #Immunology
#MedSky #PedSky #Immunology
IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy
Immunity www.cell.com/immunity/ful...
Immunity www.cell.com/immunity/ful...
IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy
Cytokines optimize and fine-tune effector T cell responses. Here, Jiang et al. utilize
IL-9, with scarce receptor expression in normal tissues, to boost IL-9R engineered
T cells for cancer therapy. IL...
www.cell.com
November 22, 2025 at 7:40 AM
IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy
Immunity www.cell.com/immunity/ful...
Immunity www.cell.com/immunity/ful...
🥷“Lab manager in immunology and spatial biology”
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
Lab manager inom immunologi och spatiell biolog | Eduardo Villablanca
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
“Lab manager in immunology and spatial biology”
Come join the Engblom and Villablanca labs! A lab manager position is avail...
www.linkedin.com
November 20, 2025 at 4:29 PM
🥷“Lab manager in immunology and spatial biology”
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
Open position not only to work in my lab but also the Engblom lab!!👇🏼👇🏾👇👇🏿
Join us!
www.linkedin.com/posts/eduard...
42 ectopic oral species found in the gut could be predictive of systemic diseases 😲
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Oral microbiome shows rising importance in human health. Cha et al. present the human
reference oral microbiome (HROM), comprising 72,641 high-quality genomes from 3,426
species, including 2,019 previ...
www.cell.com
November 19, 2025 at 8:49 PM
42 ectopic oral species found in the gut could be predictive of systemic diseases 😲
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
A high-quality genomic catalog of the human oral microbiome broadens its phylogeny and clinical insights
Cell Host & Microbe www.cell.com/cell-host-mi...
“Women who consumed the highest amounts of ultraprocessed foods — 10 servings per day on average — had a 45 percent higher risk of developing conventional adenomas, compared with those who consumed the lowest amounts”
www.linkedin.com/posts/harvar...
www.linkedin.com/posts/harvar...
Researchers link ultraprocessed foods to precancerous polyps — Harvard Gazette | Harvard University
Colorectal cancer diagnoses have become increasingly common in adults 50 or younger in recent years, particularly in high-income countries like the U.S. A new study led by Harvard and Mass General Bri...
www.linkedin.com
November 18, 2025 at 6:56 AM
“Women who consumed the highest amounts of ultraprocessed foods — 10 servings per day on average — had a 45 percent higher risk of developing conventional adenomas, compared with those who consumed the lowest amounts”
www.linkedin.com/posts/harvar...
www.linkedin.com/posts/harvar...
Karolinska Institutet is recruiting three Assistant Professors through the @SciLifeLab and @DDLS programs!
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
Call for SciLifeLab and DDLS Fellows 2025
Karolinska Institutet is recruiting three Assistant Professors in two programs tied to SciLifeLab. SciLifeLab and DDLS Fellows (Assistant Professors) are six-year positions with generous recruitment p...
news.ki.se
October 28, 2025 at 5:34 PM
Karolinska Institutet is recruiting three Assistant Professors through the @SciLifeLab and @DDLS programs!
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
These six-year positions come with generous support packages and a strong research environment.
Apply by Nov 15, 2025
#academiajobs #sciencelife #KI #SciLifeLab
news.ki.se/call-for-sci...
Packed room for @reinacampos.bsky.social’s talk at @cmm @ki.se!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
October 28, 2025 at 11:21 AM
Packed room for @reinacampos.bsky.social’s talk at @cmm @ki.se!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!
Miguel presented stunning insights into how spatial cues instruct T cells in tissue barriers. Cutting-edge and deeply inspiring research!