Endocrine Connections
@endoconnect.bsky.social
An Open Access, peer-reviewed journal from Society for Endocrinology & European Society of Endocrinology. Publishing basic, translational and clinical research in all areas of endocrinology.
Can benign thyroid enlargement cause arterial compression and neurological symptoms?
A new systematic review by Ammar Matthew Hudefi et al. examines this rare complication, including its clinical presentation, diagnosis, management and reported outcomes.
🔗 doi.org/10.1530/EC-26-0521
A new systematic review by Ammar Matthew Hudefi et al. examines this rare complication, including its clinical presentation, diagnosis, management and reported outcomes.
🔗 doi.org/10.1530/EC-26-0521
October 6, 2026 at 10:21 AM
Can benign thyroid enlargement cause arterial compression and neurological symptoms?
A new systematic review by Ammar Matthew Hudefi et al. examines this rare complication, including its clinical presentation, diagnosis, management and reported outcomes.
🔗 doi.org/10.1530/EC-26-0521
A new systematic review by Ammar Matthew Hudefi et al. examines this rare complication, including its clinical presentation, diagnosis, management and reported outcomes.
🔗 doi.org/10.1530/EC-26-0521
New research in our Barocrinology collection 🔬
Sreevatsa Tatachar et al. examine post-bariatric hypoglycaemia following Roux-en-Y gastric bypass, highlighting its variable presentation and the importance of individualised, multidisciplinary management.
🔗 doi.org/10.1530/EC-26-0480
Sreevatsa Tatachar et al. examine post-bariatric hypoglycaemia following Roux-en-Y gastric bypass, highlighting its variable presentation and the importance of individualised, multidisciplinary management.
🔗 doi.org/10.1530/EC-26-0480
October 2, 2026 at 3:41 PM
New research in our Barocrinology collection 🔬
Sreevatsa Tatachar et al. examine post-bariatric hypoglycaemia following Roux-en-Y gastric bypass, highlighting its variable presentation and the importance of individualised, multidisciplinary management.
🔗 doi.org/10.1530/EC-26-0480
Sreevatsa Tatachar et al. examine post-bariatric hypoglycaemia following Roux-en-Y gastric bypass, highlighting its variable presentation and the importance of individualised, multidisciplinary management.
🔗 doi.org/10.1530/EC-26-0480
Final PMOS Awareness Month Research Highlight
Gabriela Rosas et al. found that prenatal estradiol valerate exposure in rats led to reproductive disruptions at puberty that progressed to a PMOS-like phenotype in adulthood.
doi.org/10.1530/EC-2...
Gabriela Rosas et al. found that prenatal estradiol valerate exposure in rats led to reproductive disruptions at puberty that progressed to a PMOS-like phenotype in adulthood.
doi.org/10.1530/EC-2...
September 30, 2026 at 1:20 PM
Final PMOS Awareness Month Research Highlight
Gabriela Rosas et al. found that prenatal estradiol valerate exposure in rats led to reproductive disruptions at puberty that progressed to a PMOS-like phenotype in adulthood.
doi.org/10.1530/EC-2...
Gabriela Rosas et al. found that prenatal estradiol valerate exposure in rats led to reproductive disruptions at puberty that progressed to a PMOS-like phenotype in adulthood.
doi.org/10.1530/EC-2...
🦴 New research by Christos Gravvanis et al. examines vitamin D optimization in adults with Langerhans cell histiocytosis.
Vitamin D optimisation was associated with improvements in selected quality-of-life domains and favourable changes in bone metabolism markers.
🔗 doi.org/10.1530/EC-26-0382
Vitamin D optimisation was associated with improvements in selected quality-of-life domains and favourable changes in bone metabolism markers.
🔗 doi.org/10.1530/EC-26-0382
September 28, 2026 at 2:32 PM
🦴 New research by Christos Gravvanis et al. examines vitamin D optimization in adults with Langerhans cell histiocytosis.
Vitamin D optimisation was associated with improvements in selected quality-of-life domains and favourable changes in bone metabolism markers.
🔗 doi.org/10.1530/EC-26-0382
Vitamin D optimisation was associated with improvements in selected quality-of-life domains and favourable changes in bone metabolism markers.
🔗 doi.org/10.1530/EC-26-0382
How should clinicians manage current or previous non-medical androgen use?
A new Society for Endocrinology position statement in Endocrine Connections reviews the evidence on health consequences, recovery following cessation and management strategies.
🔗 Read here: doi.org/10.1530/EC-2...
A new Society for Endocrinology position statement in Endocrine Connections reviews the evidence on health consequences, recovery following cessation and management strategies.
🔗 Read here: doi.org/10.1530/EC-2...
September 23, 2026 at 2:14 PM
How should clinicians manage current or previous non-medical androgen use?
A new Society for Endocrinology position statement in Endocrine Connections reviews the evidence on health consequences, recovery following cessation and management strategies.
🔗 Read here: doi.org/10.1530/EC-2...
A new Society for Endocrinology position statement in Endocrine Connections reviews the evidence on health consequences, recovery following cessation and management strategies.
🔗 Read here: doi.org/10.1530/EC-2...
🔬 PMOS Awareness Month | Research Highlight
Sifu Ha et al. developed and externally validated a model to predict clinical pregnancy within 12 months in women with PMOS (previously PCOS), supporting more individualised pregnancy counselling.
doi.org/10.1530/EC-2...
Sifu Ha et al. developed and externally validated a model to predict clinical pregnancy within 12 months in women with PMOS (previously PCOS), supporting more individualised pregnancy counselling.
doi.org/10.1530/EC-2...
September 22, 2026 at 10:58 AM
🔬 PMOS Awareness Month | Research Highlight
Sifu Ha et al. developed and externally validated a model to predict clinical pregnancy within 12 months in women with PMOS (previously PCOS), supporting more individualised pregnancy counselling.
doi.org/10.1530/EC-2...
Sifu Ha et al. developed and externally validated a model to predict clinical pregnancy within 12 months in women with PMOS (previously PCOS), supporting more individualised pregnancy counselling.
doi.org/10.1530/EC-2...
New in Endocrine Connections: AI is emerging as a valuable tool in the evaluation and management of thyroid nodules and cancer.
This new review explores current evidence, clinical applications and the importance of real-world validation.
🔗 doi.org/10.1530/EC-2...
This new review explores current evidence, clinical applications and the importance of real-world validation.
🔗 doi.org/10.1530/EC-2...
September 17, 2026 at 1:01 PM
New in Endocrine Connections: AI is emerging as a valuable tool in the evaluation and management of thyroid nodules and cancer.
This new review explores current evidence, clinical applications and the importance of real-world validation.
🔗 doi.org/10.1530/EC-2...
This new review explores current evidence, clinical applications and the importance of real-world validation.
🔗 doi.org/10.1530/EC-2...
🔬 PMOS Awareness Month | Research Highlight
Xueming Huang et al. review links between microbiota and androgen metabolism in PMOS (previously PCOS), including the potential role of Toll-like receptors (TLRs).
🔗Read here: doi.org/10.1530/EC-2...
Xueming Huang et al. review links between microbiota and androgen metabolism in PMOS (previously PCOS), including the potential role of Toll-like receptors (TLRs).
🔗Read here: doi.org/10.1530/EC-2...
September 15, 2026 at 8:14 AM
🔬 PMOS Awareness Month | Research Highlight
Xueming Huang et al. review links between microbiota and androgen metabolism in PMOS (previously PCOS), including the potential role of Toll-like receptors (TLRs).
🔗Read here: doi.org/10.1530/EC-2...
Xueming Huang et al. review links between microbiota and androgen metabolism in PMOS (previously PCOS), including the potential role of Toll-like receptors (TLRs).
🔗Read here: doi.org/10.1530/EC-2...
How is systemic treatment for adrenal malignancies evolving?
Jorge H Hernandez-Felix et al. review current and emerging approaches for adrenocortical carcinoma and pheochromocytoma/paraganglioma.
Part of the Pearls and Pitfalls in Adrenal Malignancies collection.
🔗 doi.org/10.1530/EC-2...
Jorge H Hernandez-Felix et al. review current and emerging approaches for adrenocortical carcinoma and pheochromocytoma/paraganglioma.
Part of the Pearls and Pitfalls in Adrenal Malignancies collection.
🔗 doi.org/10.1530/EC-2...
September 11, 2026 at 2:55 PM
How is systemic treatment for adrenal malignancies evolving?
Jorge H Hernandez-Felix et al. review current and emerging approaches for adrenocortical carcinoma and pheochromocytoma/paraganglioma.
Part of the Pearls and Pitfalls in Adrenal Malignancies collection.
🔗 doi.org/10.1530/EC-2...
Jorge H Hernandez-Felix et al. review current and emerging approaches for adrenocortical carcinoma and pheochromocytoma/paraganglioma.
Part of the Pearls and Pitfalls in Adrenal Malignancies collection.
🔗 doi.org/10.1530/EC-2...
🔬 PMOS Awareness Month: Research Highlight
Marine Monney et al. review the potential role of GLP-1 receptor agonists in PCOS, including their effects on weight, menstrual cycles, testosterone levels and glucose homeostasis.
🔗Read the full article here: doi.org/10.1530/EC-2...
Marine Monney et al. review the potential role of GLP-1 receptor agonists in PCOS, including their effects on weight, menstrual cycles, testosterone levels and glucose homeostasis.
🔗Read the full article here: doi.org/10.1530/EC-2...
September 7, 2026 at 3:39 PM
🔬 PMOS Awareness Month: Research Highlight
Marine Monney et al. review the potential role of GLP-1 receptor agonists in PCOS, including their effects on weight, menstrual cycles, testosterone levels and glucose homeostasis.
🔗Read the full article here: doi.org/10.1530/EC-2...
Marine Monney et al. review the potential role of GLP-1 receptor agonists in PCOS, including their effects on weight, menstrual cycles, testosterone levels and glucose homeostasis.
🔗Read the full article here: doi.org/10.1530/EC-2...
What does effective transition in care look like for patients with rare endocrine conditions?
Explore the articles published so far in the Endo-ERN Vol II: Rare Diseases and Transition in Care special collection in Endocrine Connections.
🔗 journals.bioscientifica.com/ec/pages/end...
Explore the articles published so far in the Endo-ERN Vol II: Rare Diseases and Transition in Care special collection in Endocrine Connections.
🔗 journals.bioscientifica.com/ec/pages/end...
September 4, 2026 at 3:27 PM
What does effective transition in care look like for patients with rare endocrine conditions?
Explore the articles published so far in the Endo-ERN Vol II: Rare Diseases and Transition in Care special collection in Endocrine Connections.
🔗 journals.bioscientifica.com/ec/pages/end...
Explore the articles published so far in the Endo-ERN Vol II: Rare Diseases and Transition in Care special collection in Endocrine Connections.
🔗 journals.bioscientifica.com/ec/pages/end...
🔬 PMOS Research Highlight
Zhen Wang et al. explore age-specific AMH screening criteria for PMOS, identifying different thresholds across three age groups. The findings showed high sensitivity, specificity and accuracy, but further validation is needed.
doi.org/10.1530/EC-2...
Zhen Wang et al. explore age-specific AMH screening criteria for PMOS, identifying different thresholds across three age groups. The findings showed high sensitivity, specificity and accuracy, but further validation is needed.
doi.org/10.1530/EC-2...
September 2, 2026 at 11:00 AM
🔬 PMOS Research Highlight
Zhen Wang et al. explore age-specific AMH screening criteria for PMOS, identifying different thresholds across three age groups. The findings showed high sensitivity, specificity and accuracy, but further validation is needed.
doi.org/10.1530/EC-2...
Zhen Wang et al. explore age-specific AMH screening criteria for PMOS, identifying different thresholds across three age groups. The findings showed high sensitivity, specificity and accuracy, but further validation is needed.
doi.org/10.1530/EC-2...
September is PMOS Awareness Month
Previously known as PCOS, Polyendocrine Metabolic Ovarian Syndrome (PMOS) reflects the condition’s endocrine, metabolic & reproductive implications. This month, we will highlight research advancing our understanding of PMOS.
www.yourhormones.info/endocrine-co...
Previously known as PCOS, Polyendocrine Metabolic Ovarian Syndrome (PMOS) reflects the condition’s endocrine, metabolic & reproductive implications. This month, we will highlight research advancing our understanding of PMOS.
www.yourhormones.info/endocrine-co...
September 1, 2026 at 12:17 PM
September is PMOS Awareness Month
Previously known as PCOS, Polyendocrine Metabolic Ovarian Syndrome (PMOS) reflects the condition’s endocrine, metabolic & reproductive implications. This month, we will highlight research advancing our understanding of PMOS.
www.yourhormones.info/endocrine-co...
Previously known as PCOS, Polyendocrine Metabolic Ovarian Syndrome (PMOS) reflects the condition’s endocrine, metabolic & reproductive implications. This month, we will highlight research advancing our understanding of PMOS.
www.yourhormones.info/endocrine-co...
A new review by Sara Donato et al. review established and emerging biomarkers of metastatic risk in pheochromocytoma and paraganglioma, including genetic, biochemical, molecular and imaging biomarkers.
doi.org/10.1530/EC-2...
doi.org/10.1530/EC-2...
August 27, 2026 at 1:21 PM
A new review by Sara Donato et al. review established and emerging biomarkers of metastatic risk in pheochromocytoma and paraganglioma, including genetic, biochemical, molecular and imaging biomarkers.
doi.org/10.1530/EC-2...
doi.org/10.1530/EC-2...
The latest article in our Reproductive Endocrinology 2025 collection explores the emerging extragonadal roles of FSH and LH, including effects on bone, adipose tissue and the brain, and their potential links to osteoporosis, obesity and dementia.
By Se-Min Kim et al.
🔗 doi.org/10.1530/EC-2...
By Se-Min Kim et al.
🔗 doi.org/10.1530/EC-2...
August 25, 2026 at 9:26 AM
The latest article in our Reproductive Endocrinology 2025 collection explores the emerging extragonadal roles of FSH and LH, including effects on bone, adipose tissue and the brain, and their potential links to osteoporosis, obesity and dementia.
By Se-Min Kim et al.
🔗 doi.org/10.1530/EC-2...
By Se-Min Kim et al.
🔗 doi.org/10.1530/EC-2...
How specific is the desmopressin stimulation test for Cushing disease?
New research by Henrik Elenius et al. found that 50% of healthy volunteers met commonly used response criteria, highlighting the need to optimise diagnostic cut-offs.
doi.org/10.1530/EC-2...
New research by Henrik Elenius et al. found that 50% of healthy volunteers met commonly used response criteria, highlighting the need to optimise diagnostic cut-offs.
doi.org/10.1530/EC-2...
August 18, 2026 at 11:02 AM
How specific is the desmopressin stimulation test for Cushing disease?
New research by Henrik Elenius et al. found that 50% of healthy volunteers met commonly used response criteria, highlighting the need to optimise diagnostic cut-offs.
doi.org/10.1530/EC-2...
New research by Henrik Elenius et al. found that 50% of healthy volunteers met commonly used response criteria, highlighting the need to optimise diagnostic cut-offs.
doi.org/10.1530/EC-2...
New research in by Alexander Krawzow et al. finds 11-deoxycortisol had the strongest diagnostic performance for adrenal insufficiency in the overnight oral metyrapone test. Other hormone measurements and pituitary function tests may provide useful additional information.
🔗 doi.org/10.1530/EC-2...
🔗 doi.org/10.1530/EC-2...
August 11, 2026 at 1:09 PM
New research in by Alexander Krawzow et al. finds 11-deoxycortisol had the strongest diagnostic performance for adrenal insufficiency in the overnight oral metyrapone test. Other hormone measurements and pituitary function tests may provide useful additional information.
🔗 doi.org/10.1530/EC-2...
🔗 doi.org/10.1530/EC-2...
New review in our Barocrinology collection:
Wei Yang & Tricia M-M Tan explore post-bariatric hypoglycaemia, from altered gut physiology and incretin responses to emerging roles for serotonin, bile acids and the microbiome, alongside mechanism-based treatment strategies.
🔗 doi.org/10.1530/RAF-...
Wei Yang & Tricia M-M Tan explore post-bariatric hypoglycaemia, from altered gut physiology and incretin responses to emerging roles for serotonin, bile acids and the microbiome, alongside mechanism-based treatment strategies.
🔗 doi.org/10.1530/RAF-...
August 7, 2026 at 11:04 AM
New review in our Barocrinology collection:
Wei Yang & Tricia M-M Tan explore post-bariatric hypoglycaemia, from altered gut physiology and incretin responses to emerging roles for serotonin, bile acids and the microbiome, alongside mechanism-based treatment strategies.
🔗 doi.org/10.1530/RAF-...
Wei Yang & Tricia M-M Tan explore post-bariatric hypoglycaemia, from altered gut physiology and incretin responses to emerging roles for serotonin, bile acids and the microbiome, alongside mechanism-based treatment strategies.
🔗 doi.org/10.1530/RAF-...
Later menopause is often thought to reduce osteoporosis risk - but does that protection last into older age?
A new study by Zhou et al. of 5,804 postmenopausal women found no significant association between age at menopause and osteoporosis risk. 🦴
Read here: doi.org/10.1530/EC-2...
A new study by Zhou et al. of 5,804 postmenopausal women found no significant association between age at menopause and osteoporosis risk. 🦴
Read here: doi.org/10.1530/EC-2...
August 4, 2026 at 2:52 PM
Later menopause is often thought to reduce osteoporosis risk - but does that protection last into older age?
A new study by Zhou et al. of 5,804 postmenopausal women found no significant association between age at menopause and osteoporosis risk. 🦴
Read here: doi.org/10.1530/EC-2...
A new study by Zhou et al. of 5,804 postmenopausal women found no significant association between age at menopause and osteoporosis risk. 🦴
Read here: doi.org/10.1530/EC-2...
Rethinking obesity through a new endocrine lens 🔬
New commentary “A quantum approach to the endocrinology of obesity” explores the GH–IGF-1 network and its role in understanding obesity.
Part of: Barocrinology: The Science of Obesity Medicine
🔗 doi.org/10.1530/EC-2...
New commentary “A quantum approach to the endocrinology of obesity” explores the GH–IGF-1 network and its role in understanding obesity.
Part of: Barocrinology: The Science of Obesity Medicine
🔗 doi.org/10.1530/EC-2...
July 30, 2026 at 3:30 PM
Rethinking obesity through a new endocrine lens 🔬
New commentary “A quantum approach to the endocrinology of obesity” explores the GH–IGF-1 network and its role in understanding obesity.
Part of: Barocrinology: The Science of Obesity Medicine
🔗 doi.org/10.1530/EC-2...
New commentary “A quantum approach to the endocrinology of obesity” explores the GH–IGF-1 network and its role in understanding obesity.
Part of: Barocrinology: The Science of Obesity Medicine
🔗 doi.org/10.1530/EC-2...
New research by Moritz Schrenk et al. identifies type II muscle fiber atrophy in active endogenous Cushing's syndrome, with mitochondrial alterations that persisted after remission. The findings highlight the need for further mechanistic studies.
📖 doi.org/10.1530/EC-2...
📖 doi.org/10.1530/EC-2...
July 28, 2026 at 1:10 PM
New research by Moritz Schrenk et al. identifies type II muscle fiber atrophy in active endogenous Cushing's syndrome, with mitochondrial alterations that persisted after remission. The findings highlight the need for further mechanistic studies.
📖 doi.org/10.1530/EC-2...
📖 doi.org/10.1530/EC-2...
New article in our Adrenal Special Collection:
Can artificial intelligence transform adrenal imaging? A review by Mucha et al. explores AI's potential to improve the detection and characterisation of adrenal lesions, while outlining the challenges to clinical adoption.
🔗 doi.org/10.1530/EC-26-0267
Can artificial intelligence transform adrenal imaging? A review by Mucha et al. explores AI's potential to improve the detection and characterisation of adrenal lesions, while outlining the challenges to clinical adoption.
🔗 doi.org/10.1530/EC-26-0267
July 23, 2026 at 9:38 AM
New article in our Adrenal Special Collection:
Can artificial intelligence transform adrenal imaging? A review by Mucha et al. explores AI's potential to improve the detection and characterisation of adrenal lesions, while outlining the challenges to clinical adoption.
🔗 doi.org/10.1530/EC-26-0267
Can artificial intelligence transform adrenal imaging? A review by Mucha et al. explores AI's potential to improve the detection and characterisation of adrenal lesions, while outlining the challenges to clinical adoption.
🔗 doi.org/10.1530/EC-26-0267
💫 European Society of Endocrinology Member Paper Highlight
Could circular RNAs improve the diagnosis and monitoring of diabetes? This systematic review identifies promising biomarker candidates. Congratulations to the authors!
doi.org/10.1530/EC-2...
Could circular RNAs improve the diagnosis and monitoring of diabetes? This systematic review identifies promising biomarker candidates. Congratulations to the authors!
doi.org/10.1530/EC-2...
July 21, 2026 at 7:43 AM
💫 European Society of Endocrinology Member Paper Highlight
Could circular RNAs improve the diagnosis and monitoring of diabetes? This systematic review identifies promising biomarker candidates. Congratulations to the authors!
doi.org/10.1530/EC-2...
Could circular RNAs improve the diagnosis and monitoring of diabetes? This systematic review identifies promising biomarker candidates. Congratulations to the authors!
doi.org/10.1530/EC-2...
🏆 Congratulations to Ying Ke et al.! Their paper, Predicting time to glycemic stability in hospitalized type 2 diabetes patients using insulin resistance indices, has been selected as the Q2 Editors' Choice Award in Endocrine Connections.
doi.org/10.1530/EC-2...
doi.org/10.1530/EC-2...
July 7, 2026 at 11:15 AM
🏆 Congratulations to Ying Ke et al.! Their paper, Predicting time to glycemic stability in hospitalized type 2 diabetes patients using insulin resistance indices, has been selected as the Q2 Editors' Choice Award in Endocrine Connections.
doi.org/10.1530/EC-2...
doi.org/10.1530/EC-2...
New research by Yoo-Mi Kim et al: A 10-year interim analysis of over 5,000 Korean children found low rates of adverse drug reactions with recombinant human growth hormone therapy, supporting its long-term safety while highlighting the need for continued surveillance.
doi.org/10.1530/EC-2...
doi.org/10.1530/EC-2...
July 3, 2026 at 1:53 PM
New research by Yoo-Mi Kim et al: A 10-year interim analysis of over 5,000 Korean children found low rates of adverse drug reactions with recombinant human growth hormone therapy, supporting its long-term safety while highlighting the need for continued surveillance.
doi.org/10.1530/EC-2...
doi.org/10.1530/EC-2...