Felix C Tropf
@fctropf.bsky.social
Associate Professor at UCL & Nuffield College Oxford | Causal Inference & Real-World Evidence | Genomic Prediction & Polygenic Scores | Demography & Population Health
Reposted by Felix C Tropf
How do nature, nurture, and their interplay drive inequality? 🧬🧠💰
New PhD position in social science genetics at @amsterdamumc.bsky.social and @vuamsterdam.bsky.social. Your supervisors will be: Titus Galama, Aysu Okbay, and me.
Apply by 21 July: workingat.vu.nl/vacancies/ph...
Please share!
New PhD position in social science genetics at @amsterdamumc.bsky.social and @vuamsterdam.bsky.social. Your supervisors will be: Titus Galama, Aysu Okbay, and me.
Apply by 21 July: workingat.vu.nl/vacancies/ph...
Please share!
Vacancy — PhD position in Social Science Genetics – VU Amsterdam & Amsterdam UMC
Applications are invited for a PhD position in Social Science Genetics, a joint appointment at Vrije Universiteit Amsterdam and Amsterdam UMC. Eligible candidates may start their studentship between J...
workingat.vu.nl
July 14, 2026 at 2:45 PM
How do nature, nurture, and their interplay drive inequality? 🧬🧠💰
New PhD position in social science genetics at @amsterdamumc.bsky.social and @vuamsterdam.bsky.social. Your supervisors will be: Titus Galama, Aysu Okbay, and me.
Apply by 21 July: workingat.vu.nl/vacancies/ph...
Please share!
New PhD position in social science genetics at @amsterdamumc.bsky.social and @vuamsterdam.bsky.social. Your supervisors will be: Titus Galama, Aysu Okbay, and me.
Apply by 21 July: workingat.vu.nl/vacancies/ph...
Please share!
Reposted by Felix C Tropf
🚨New in PNAS: www.pnas.org/doi/abs/10.1...
Genetic principal components (PCs) are commonly used to adjust for population stratification in genetic studies.
In this paper, we quantify how much direct genetic signal is lost when using these “catch-all” adjustments. 🧵
Genetic principal components (PCs) are commonly used to adjust for population stratification in genetic studies.
In this paper, we quantify how much direct genetic signal is lost when using these “catch-all” adjustments. 🧵
Quantifying direct genetic signal captured by principal component adjustment | PNAS
Contemporary genomic studies of complex traits, such as genome-wide association studies
and polygenic index (PGI) analyses, frequently include the ...
www.pnas.org
May 7, 2026 at 5:32 AM
🚨New in PNAS: www.pnas.org/doi/abs/10.1...
Genetic principal components (PCs) are commonly used to adjust for population stratification in genetic studies.
In this paper, we quantify how much direct genetic signal is lost when using these “catch-all” adjustments. 🧵
Genetic principal components (PCs) are commonly used to adjust for population stratification in genetic studies.
In this paper, we quantify how much direct genetic signal is lost when using these “catch-all” adjustments. 🧵
Reposted by Felix C Tropf
What can we learn from automating an entire quantitative social science paper, from prompt to finished product? Thread about ongoing work with @natewilmers.bsky.social 1/12
Paper: osf.io/preprints/so...
Paper: osf.io/preprints/so...
May 8, 2026 at 12:08 PM
What can we learn from automating an entire quantitative social science paper, from prompt to finished product? Thread about ongoing work with @natewilmers.bsky.social 1/12
Paper: osf.io/preprints/so...
Paper: osf.io/preprints/so...
Reposted by Felix C Tropf
PLEASE SHARE: Serious request for a future scientific collaboration. Do I know any historians/sociologists who works with, or love working with historic ego documents. Diaries, letters, notes, etc. Especially those that describe real, or wished for, romantic partners/interests? email me, DM me!
May 13, 2026 at 5:41 AM
PLEASE SHARE: Serious request for a future scientific collaboration. Do I know any historians/sociologists who works with, or love working with historic ego documents. Diaries, letters, notes, etc. Especially those that describe real, or wished for, romantic partners/interests? email me, DM me!
Always energising to engage with cutting-edge work on assortative mating, cross-ancestry prediction, and rare variants at @ESSGN — especially with such a strong cohort of doctoral researchers at Vrije Universiteit Amsterdam.
#Sociogenomics #GeneticPrediction #ESSGN
#Sociogenomics #GeneticPrediction #ESSGN
March 27, 2026 at 8:32 AM
Always energising to engage with cutting-edge work on assortative mating, cross-ancestry prediction, and rare variants at @ESSGN — especially with such a strong cohort of doctoral researchers at Vrije Universiteit Amsterdam.
#Sociogenomics #GeneticPrediction #ESSGN
#Sociogenomics #GeneticPrediction #ESSGN
Reposted by Felix C Tropf
PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social
An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference https://www.biorxiv.org/content/10.1101/2025.05.14.653986v1
May 20, 2025 at 10:18 AM
PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social
Reposted by Felix C Tropf
Come work with me and @dr-appie.bsky.social in Amsterdam!
Me & @aysuo.bsky.social are hiring a postdoc to study gene–environment interplay in health & social inequalities 🧬
You'll analyze genomic data as part of a collaboration with Uppsala & Oslo at @amsterdamumc.bsky.social (NL)
werkenbij.amsterdamumc.org/en/vacatures...
Please RT for karma points ♥️
You'll analyze genomic data as part of a collaboration with Uppsala & Oslo at @amsterdamumc.bsky.social (NL)
werkenbij.amsterdamumc.org/en/vacatures...
Please RT for karma points ♥️
Vacatures - Postdoctoral researcher specialising in gene–environment interplay - Amsterdam UMC
Ready to unravel the complex interplay between genes and environment shaping health and society? Join our interdisciplinary team analyzing large-scale genomic data across Europe. Are you eager to contribute to groundbreaking research on health and social inequalities?
werkenbij.amsterdamumc.org
March 25, 2026 at 11:23 AM
Come work with me and @dr-appie.bsky.social in Amsterdam!
walking on clouds through marais and back. thanks for a magic (and important) research visit (grant deadline) @cris-sciencespo.bsky.social et al!
March 14, 2026 at 3:48 PM
walking on clouds through marais and back. thanks for a magic (and important) research visit (grant deadline) @cris-sciencespo.bsky.social et al!
Reposted by Felix C Tropf
There are a bunch or brief but well structured research fellowships opening up at the MRC-IEU: www.bristol.ac.uk/jobs/find/de...
Details | Working at Bristol | University of Bristol
www.bristol.ac.uk
March 5, 2026 at 8:30 PM
There are a bunch or brief but well structured research fellowships opening up at the MRC-IEU: www.bristol.ac.uk/jobs/find/de...
Interested in using polygenic scores (PGS) in social science or health research? We are running a 2-day intensive short course @stats_UCL with @timtmorris.bsky.social (20–21 April 2026): tinyurl.com/5n6hwyxy. Ideal for all quantitative researcher across Social and Health Sciences! Get started!
tinyurl.com
March 9, 2026 at 10:44 AM
Interested in using polygenic scores (PGS) in social science or health research? We are running a 2-day intensive short course @stats_UCL with @timtmorris.bsky.social (20–21 April 2026): tinyurl.com/5n6hwyxy. Ideal for all quantitative researcher across Social and Health Sciences! Get started!
Reposted by Felix C Tropf
Yo #polisky, you don't want to miss this one :)
Political Science and Genetics, odd bed fellows? Not necessarily! Listen in on this weeks episode of Born and Raised, with Sven Oskarsson, professor of political science at Uppsala university.
4. Sven Oskarsson on genetics and political science | Born and Raised
Why on earth would a political scientist do research in genetics? In this episode, our hosts met up with Sven Oskarsson in the supremely cozy Alinska Library at Uppsala university to let him spill the...
essgn.podbean.com
March 6, 2026 at 12:42 PM
Yo #polisky, you don't want to miss this one :)
In 2035, 50% of the NHS d- patient interactions are supposed to be genetically informed. Festival of genomics and biodata in London.
January 28, 2026 at 9:15 AM
In 2035, 50% of the NHS d- patient interactions are supposed to be genetically informed. Festival of genomics and biodata in London.
Welcoming the rising star of sociogenomics in London. Thanks for sharing a meal @furuyashiro.bsky.social @harvard.edu @clscohorts.bsky.social .
January 27, 2026 at 8:31 PM
Welcoming the rising star of sociogenomics in London. Thanks for sharing a meal @furuyashiro.bsky.social @harvard.edu @clscohorts.bsky.social .
Reposted by Felix C Tropf
@fctropf.bsky.social and I are running a 2-day short course in London on 20/21 April that will provide an introduction to polygenic scores. The course will cover creation of polygenic scores, their strengths and limitations, and ethical issues around their use. Further info at shorturl.at/8gUcu.
Introduction to polygenic score analyses in the social, behavioural, and health sciences
This 2-day course will provide social scientists with the knowledge and skills needed to understand the creation of polygenic scores, critically interpret their use in studies, and integrate them into...
shorturl.at
January 19, 2026 at 5:22 PM
@fctropf.bsky.social and I are running a 2-day short course in London on 20/21 April that will provide an introduction to polygenic scores. The course will cover creation of polygenic scores, their strengths and limitations, and ethical issues around their use. Further info at shorturl.at/8gUcu.
Reposted by Felix C Tropf
I wrote about missing heritability, "missing environmentality," and why I still think twin studies are interesting and valuable: kathrynpaigeharden.substack.com/p/twins-are-...
Twins Are So Much More Interesting Than Heritability Estimates
On starting places, "missing environmentality," and the Waddington landscape of life
kathrynpaigeharden.substack.com
December 4, 2025 at 7:08 PM
I wrote about missing heritability, "missing environmentality," and why I still think twin studies are interesting and valuable: kathrynpaigeharden.substack.com/p/twins-are-...
Behavioral, social and health scientists: if you’d like to combine social and genetic data, this is for you: shorturl.at/8gUcu. This course in London features all aspects from data collection to model estimation in our local cohort data - and the incredible @timtmorris.bsky.social as instructor.
Introduction to genetic data analysis in the social, behavioural, and health sciences
This 4-day course will provide social scientists with the knowledge and skills needed to analyse genetic data, critically interpret results, and integrate genetics into their research.
shorturl.at
November 13, 2025 at 3:59 PM
Behavioral, social and health scientists: if you’d like to combine social and genetic data, this is for you: shorturl.at/8gUcu. This course in London features all aspects from data collection to model estimation in our local cohort data - and the incredible @timtmorris.bsky.social as instructor.
Reposted by Felix C Tropf
"Offering genetic predictions for embryos to improve health outcomes latches onto a privatization logic that does exactly the opposite and hence erodes a system based on social equality and solidarity."
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
There’s a new kid in town!
Companies are now selling IVF and embryo selection based on genetic testing for traits related to health and even intelligence.
We outline methodological and ethical concerns, and warn against risks for social inequality.
With the fantastic @gaiaghirardi.bsky.social
Companies are now selling IVF and embryo selection based on genetic testing for traits related to health and even intelligence.
We outline methodological and ethical concerns, and warn against risks for social inequality.
With the fantastic @gaiaghirardi.bsky.social
Embryo selection based on polygenic prediction risks reinforcing social inequality
The rise of companies offering embryo selection based on genetic testing has triggered heated debate about ethical acceptability, as well as the accuracy and scientific validity of these techniques. W...
www.fertstert.org
November 13, 2025 at 1:47 PM
"Offering genetic predictions for embryos to improve health outcomes latches onto a privatization logic that does exactly the opposite and hence erodes a system based on social equality and solidarity."
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
Reposted by Felix C Tropf
1/ 🚨New paper in Nature Genetics
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic associations with educational fields - Nature Genetics
Genome-wide analyses of 10 educational fields identify 17 associated loci. Analysis of genetic clustering across specializations identifies two key dimensions that show genetic overlap with personalit...
www.nature.com
November 4, 2025 at 10:23 AM
1/ 🚨New paper in Nature Genetics
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Reposted by Felix C Tropf
Nice commentary by @fctropf.bsky.social reflecting on our study on not having sex: www.pnas.org/doi/10.1073/...
(for full study, see quoted tweet below)
(for full study, see quoted tweet below)
October 28, 2025 at 2:55 PM
Nice commentary by @fctropf.bsky.social reflecting on our study on not having sex: www.pnas.org/doi/10.1073/...
(for full study, see quoted tweet below)
(for full study, see quoted tweet below)
Reposted by Felix C Tropf
Are you a UCL Sociologist? Apply to join UCL Sociology Network's Coordinating Group. Contribute to the Network’s wide-ranging programme of activities and share news of important sociological developments tinyurl.com/2ut5dttz
September 22, 2025 at 2:33 PM
Are you a UCL Sociologist? Apply to join UCL Sociology Network's Coordinating Group. Contribute to the Network’s wide-ranging programme of activities and share news of important sociological developments tinyurl.com/2ut5dttz
Reposted by Felix C Tropf
WE ARE HIRING! 2 Lecturers in Quantitative Social Science. Want a friendly interdisciplinary department in one of the world's most vibrant cities? This just might be for you.
Apply by: 10 Oct
www.ucl.ac.uk/work-at-ucl/...
Apply by: 10 Oct
www.ucl.ac.uk/work-at-ucl/...
September 1, 2025 at 1:59 PM
WE ARE HIRING! 2 Lecturers in Quantitative Social Science. Want a friendly interdisciplinary department in one of the world's most vibrant cities? This just might be for you.
Apply by: 10 Oct
www.ucl.ac.uk/work-at-ucl/...
Apply by: 10 Oct
www.ucl.ac.uk/work-at-ucl/...
Reposted by Felix C Tropf
Another job alert! Join us @sociologyoxford.bsky.social as a postdoc on @ewabatyra.bsky.social's ERC project. A great three-year position to work in the area of fertility and reproductive behaviour. www.sociology.ox.ac.uk/event/postdo...
August 21, 2025 at 2:13 PM
Another job alert! Join us @sociologyoxford.bsky.social as a postdoc on @ewabatyra.bsky.social's ERC project. A great three-year position to work in the area of fertility and reproductive behaviour. www.sociology.ox.ac.uk/event/postdo...
Reposted by Felix C Tropf
Call for abstracts: genetics, economic & social issues.
We're hosting a 1-day workshop on using genetic data to examine economic & social issues on 12th December at UCL’s Social Research Institute. More info & submission at link below #genetics #socialscience #economics #cohort
bit.ly/41EnPmu
We're hosting a 1-day workshop on using genetic data to examine economic & social issues on 12th December at UCL’s Social Research Institute. More info & submission at link below #genetics #socialscience #economics #cohort
bit.ly/41EnPmu
Microsoft Forms
bit.ly
August 13, 2025 at 12:06 PM
Call for abstracts: genetics, economic & social issues.
We're hosting a 1-day workshop on using genetic data to examine economic & social issues on 12th December at UCL’s Social Research Institute. More info & submission at link below #genetics #socialscience #economics #cohort
bit.ly/41EnPmu
We're hosting a 1-day workshop on using genetic data to examine economic & social issues on 12th December at UCL’s Social Research Institute. More info & submission at link below #genetics #socialscience #economics #cohort
bit.ly/41EnPmu
Reposted by Felix C Tropf
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
February 14, 2025 at 1:30 PM
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵