Gilles Laverny
@gilleslaverny.bsky.social
Group leader pathophysiological roles of vitamin D signaling @igbmc France
#rarediseases #prostatecancer #singlecell #spatialtranscriptomics
#rarediseases #prostatecancer #singlecell #spatialtranscriptomics
A role for vitamin D and neutrophils in prostate cancer dissemination 🤔
Our latest work highlights
👉 the protective role of vitamin D signaling in prostatic epithelial cells
👉 the impact of circulating neutrophils in cancer dissemination in the liver.
Our latest work highlights
👉 the protective role of vitamin D signaling in prostatic epithelial cells
👉 the impact of circulating neutrophils in cancer dissemination in the liver.
Impaired #vitaminD signaling reveals #neutrophils as key drivers of #ProstateCancer dissemination
🗞️ doi.org/10.1038/s44321-026-00417-5
by K. Len-Tayon, @gilleslaverny.bsky.social & colleagues @igbmc.bsky.social
🗞️ doi.org/10.1038/s44321-026-00417-5
by K. Len-Tayon, @gilleslaverny.bsky.social & colleagues @igbmc.bsky.social
April 27, 2026 at 6:58 PM
A role for vitamin D and neutrophils in prostate cancer dissemination 🤔
Our latest work highlights
👉 the protective role of vitamin D signaling in prostatic epithelial cells
👉 the impact of circulating neutrophils in cancer dissemination in the liver.
Our latest work highlights
👉 the protective role of vitamin D signaling in prostatic epithelial cells
👉 the impact of circulating neutrophils in cancer dissemination in the liver.
Reposted by Gilles Laverny
Targeting pre-existing club-like cells in #ProstateCancer potentiates #AndrogenDeprivationTherapy by M. Baurès, F. Rambow, @goffinlab.bsky.social & colleagues @inem-necker.bsky.social and Institute for AI in Medicine (IKIM)
➡️ doi.org/10.1038/s443...
➡️ doi.org/10.1038/s443...
February 2, 2026 at 4:22 PM
Targeting pre-existing club-like cells in #ProstateCancer potentiates #AndrogenDeprivationTherapy by M. Baurès, F. Rambow, @goffinlab.bsky.social & colleagues @inem-necker.bsky.social and Institute for AI in Medicine (IKIM)
➡️ doi.org/10.1038/s443...
➡️ doi.org/10.1038/s443...
Very proud to contribute to this work from @goffinlab.bsky.social.
We took advantage of the GeoMx technology @brukerspatial.bsky.social at the @igbmc.bsky.social spatial transcriptomics platform.
We took advantage of the GeoMx technology @brukerspatial.bsky.social at the @igbmc.bsky.social spatial transcriptomics platform.
[PUBLICATION] The @goffinlab.bsky.social lab shows a promising therapeutic strategy to mitigate prostate cancer progression towards CRPC — now out in EMBO Molecular Medicine @embomolmed.org
👏🏼 Co-first authors: Manon Baurès & Anne-Sophie Vieira Aleixo
🔗 link.springer.com/article/10.1...
👏🏼 Co-first authors: Manon Baurès & Anne-Sophie Vieira Aleixo
🔗 link.springer.com/article/10.1...
February 15, 2026 at 8:32 AM
Very proud to contribute to this work from @goffinlab.bsky.social.
We took advantage of the GeoMx technology @brukerspatial.bsky.social at the @igbmc.bsky.social spatial transcriptomics platform.
We took advantage of the GeoMx technology @brukerspatial.bsky.social at the @igbmc.bsky.social spatial transcriptomics platform.
🚨 News from the lab
🥳The generation and characterisation of a new mouse model of #myositis is now online in RMDopen.
rmdopen.bmj.com/content/rmdo...
wonderful work from Margherita Giannini and a great collaboration with Pr. Alain Meyer.
@inserm.fr @igbmc.bsky.social @cnrs.fr
🥳The generation and characterisation of a new mouse model of #myositis is now online in RMDopen.
rmdopen.bmj.com/content/rmdo...
wonderful work from Margherita Giannini and a great collaboration with Pr. Alain Meyer.
@inserm.fr @igbmc.bsky.social @cnrs.fr
rmdopen.bmj.com
March 6, 2025 at 7:58 PM
🚨 News from the lab
🥳The generation and characterisation of a new mouse model of #myositis is now online in RMDopen.
rmdopen.bmj.com/content/rmdo...
wonderful work from Margherita Giannini and a great collaboration with Pr. Alain Meyer.
@inserm.fr @igbmc.bsky.social @cnrs.fr
🥳The generation and characterisation of a new mouse model of #myositis is now online in RMDopen.
rmdopen.bmj.com/content/rmdo...
wonderful work from Margherita Giannini and a great collaboration with Pr. Alain Meyer.
@inserm.fr @igbmc.bsky.social @cnrs.fr
⁉️ Willing to understand the mechanisms underlying prostate cancer progression
🧑🔬 Go and check the new work from our lab 👇
🚀 Congrats @yanushkod.bsky.social and @beatrizgerman.bsky.social
@cnrs.bsky.social @inserm.fr @fondationarc.bsky.social @unistra.fr
www.nature.com/articles/s41...
🧑🔬 Go and check the new work from our lab 👇
🚀 Congrats @yanushkod.bsky.social and @beatrizgerman.bsky.social
@cnrs.bsky.social @inserm.fr @fondationarc.bsky.social @unistra.fr
www.nature.com/articles/s41...
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment - Cell Death & Disease
Cell Death & Disease - p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment
www.nature.com
January 30, 2025 at 8:12 PM
⁉️ Willing to understand the mechanisms underlying prostate cancer progression
🧑🔬 Go and check the new work from our lab 👇
🚀 Congrats @yanushkod.bsky.social and @beatrizgerman.bsky.social
@cnrs.bsky.social @inserm.fr @fondationarc.bsky.social @unistra.fr
www.nature.com/articles/s41...
🧑🔬 Go and check the new work from our lab 👇
🚀 Congrats @yanushkod.bsky.social and @beatrizgerman.bsky.social
@cnrs.bsky.social @inserm.fr @fondationarc.bsky.social @unistra.fr
www.nature.com/articles/s41...
Reposted by Gilles Laverny
Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)
The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes
Nature Metabolism - Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.
rdcu.be
January 13, 2025 at 11:00 AM
Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)
🚨News from the lab 👩🔬
🗞️ find out the interview of our newly @inserm.fr researcher Daniela Rovito by the Rare Diseases Network OSCAR
4e24w.r.bh.d.sendibt3.com/mk/mr/sh/SMJ...
🗞️ find out the interview of our newly @inserm.fr researcher Daniela Rovito by the Rare Diseases Network OSCAR
4e24w.r.bh.d.sendibt3.com/mk/mr/sh/SMJ...
📩 Les News Scientifiques d'OSCAR - Janvier 2025
4e24w.r.bh.d.sendibt3.com
January 11, 2025 at 7:30 AM
🚨News from the lab 👩🔬
🗞️ find out the interview of our newly @inserm.fr researcher Daniela Rovito by the Rare Diseases Network OSCAR
4e24w.r.bh.d.sendibt3.com/mk/mr/sh/SMJ...
🗞️ find out the interview of our newly @inserm.fr researcher Daniela Rovito by the Rare Diseases Network OSCAR
4e24w.r.bh.d.sendibt3.com/mk/mr/sh/SMJ...
Reposted by Gilles Laverny
🎄Christmas arrived in the Lab :-) one original paper and one review accepted before the holidays. Stay tune for the releases 🔬👩🔬🧫
December 20, 2024 at 7:06 AM
🎄Christmas arrived in the Lab :-) one original paper and one review accepted before the holidays. Stay tune for the releases 🔬👩🔬🧫
Lovely Christmas party with the group after such an amazing year! 🎄🎅Hope the best is to come next year Thanks to the Secret Santa 😜
December 19, 2024 at 10:38 PM
Lovely Christmas party with the group after such an amazing year! 🎄🎅Hope the best is to come next year Thanks to the Secret Santa 😜
Reposted by Gilles Laverny
New Open Science Feed
This feed will pick up posts containing the phrases “open science,” “open research,” and “open scholarship” as well as the hashtags #openscience and #openresearch (not case sensitive)!
This feed will pick up posts containing the phrases “open science,” “open research,” and “open scholarship” as well as the hashtags #openscience and #openresearch (not case sensitive)!
December 14, 2024 at 12:43 PM
New Open Science Feed
This feed will pick up posts containing the phrases “open science,” “open research,” and “open scholarship” as well as the hashtags #openscience and #openresearch (not case sensitive)!
This feed will pick up posts containing the phrases “open science,” “open research,” and “open scholarship” as well as the hashtags #openscience and #openresearch (not case sensitive)!
Reposted by Gilles Laverny
A Review in Nature Reviews Genetics discusses how biobanks facilitate genetics research towards advancing precision medicine and overviews potential solutions to their current limitations. https://go.nature.com/3OLSnw1 🔒
December 9, 2024 at 1:43 PM
A Review in Nature Reviews Genetics discusses how biobanks facilitate genetics research towards advancing precision medicine and overviews potential solutions to their current limitations. https://go.nature.com/3OLSnw1 🔒