Institute of Developmental & Regenerative Medicine
@idrm.ox.ac.uk
The Institute of Developmental & Regenerative Medicine combines cardiovascular science, neuroscience and immunology to develop new drugs and therapies.
Clinical research and patient care go hand in hand.
Hear Dr Fatima Dhalla from the Holländer Group discuss why in this excellent interview.
Hear Dr Fatima Dhalla from the Holländer Group discuss why in this excellent interview.
How do the best research questions arise?
Dr Fatima Dhalla discusses why clinical immunologists are uniquely placed to identify the questions that matter most to patients, and how research can complement a clinical career.
Watch the full interview: vist.ly/5c3uy
Dr Fatima Dhalla discusses why clinical immunologists are uniquely placed to identify the questions that matter most to patients, and how research can complement a clinical career.
Watch the full interview: vist.ly/5c3uy
July 22, 2026 at 2:53 PM
Clinical research and patient care go hand in hand.
Hear Dr Fatima Dhalla from the Holländer Group discuss why in this excellent interview.
Hear Dr Fatima Dhalla from the Holländer Group discuss why in this excellent interview.
The Oxford-ZEISS Centre of Excellence in Biomedical Imaging between @kiroxford.bsky.social and the Institute of Developmental & Regenerative Medicine has become the first to acquire the new ZEISS Lightfield 4D system.
Read more: www.idrm.ox.ac.uk/news-and-fea...
Read more: www.idrm.ox.ac.uk/news-and-fea...
July 17, 2026 at 1:48 PM
The Oxford-ZEISS Centre of Excellence in Biomedical Imaging between @kiroxford.bsky.social and the Institute of Developmental & Regenerative Medicine has become the first to acquire the new ZEISS Lightfield 4D system.
Read more: www.idrm.ox.ac.uk/news-and-fea...
Read more: www.idrm.ox.ac.uk/news-and-fea...
We were delighted to bring colleagues together to celebrate Prof Paul Riley's election to the Fellowship of the Royal Society.
In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.
In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.
June 24, 2026 at 5:16 PM
We were delighted to bring colleagues together to celebrate Prof Paul Riley's election to the Fellowship of the Royal Society.
In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.
In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.
How do immune cells help heal the heart? In the latest episode of the @stemcellpodcast.com, Dr. Simões @simoesfilipa.bsky.social, Group Leader at IDRM and Co-Director of the Oxford Organoid Hub, discusses her research on how macrophages shape heart development, repair, and regeneration.
📢 Our next episode is live!
Dr. Filipa Simões (@simoesfilipa.bsky.social) at @ox.ac.uk discusses how macrophages shape heart development, repair, and regeneration, and how cellular crosstalk within the cardiac niche influences tissue outcomes after injury.
🎙️Listen now: https://bit.ly/4dYixJs
Dr. Filipa Simões (@simoesfilipa.bsky.social) at @ox.ac.uk discusses how macrophages shape heart development, repair, and regeneration, and how cellular crosstalk within the cardiac niche influences tissue outcomes after injury.
🎙️Listen now: https://bit.ly/4dYixJs
June 11, 2026 at 3:00 PM
How do immune cells help heal the heart? In the latest episode of the @stemcellpodcast.com, Dr. Simões @simoesfilipa.bsky.social, Group Leader at IDRM and Co-Director of the Oxford Organoid Hub, discusses her research on how macrophages shape heart development, repair, and regeneration.
In a new expert commentary, Associate Professor Thomas Roberts discusses a paper published in Gene Therapy, which examines the progress and challenges of AAV microdystrophin gene replacement therapies for #DuchenneMuscularDystrophy.
Read more: tinyurl.com/2rzbyv6s
Read more: tinyurl.com/2rzbyv6s
June 9, 2026 at 11:38 AM
In a new expert commentary, Associate Professor Thomas Roberts discusses a paper published in Gene Therapy, which examines the progress and challenges of AAV microdystrophin gene replacement therapies for #DuchenneMuscularDystrophy.
Read more: tinyurl.com/2rzbyv6s
Read more: tinyurl.com/2rzbyv6s
We are excited to share that Professor Paul Riley has been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences, for his outstanding contribution to regenerative medicine and cardiovascular science.
www.idrm.ox.ac.uk/news-and-fea...
@oxforddpag.bsky.social
www.idrm.ox.ac.uk/news-and-fea...
@oxforddpag.bsky.social
May 27, 2026 at 11:39 AM
We are excited to share that Professor Paul Riley has been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences, for his outstanding contribution to regenerative medicine and cardiovascular science.
www.idrm.ox.ac.uk/news-and-fea...
@oxforddpag.bsky.social
www.idrm.ox.ac.uk/news-and-fea...
@oxforddpag.bsky.social
The Oxford-ZEISS CoE in Biomedical Imaging, between the IDRM and @kiroxford.bsky.social at @ox.ac.uk, in collaboration with @zeiss-microscopy.bsky.social, is developing a new cutting-edge imaging technology: Selective Plane Illumination Lattice Light Sheet Microscopy.
🔗https://tinyurl.com/mu6xvpwc
🔗https://tinyurl.com/mu6xvpwc
April 14, 2026 at 10:26 AM
The Oxford-ZEISS CoE in Biomedical Imaging, between the IDRM and @kiroxford.bsky.social at @ox.ac.uk, in collaboration with @zeiss-microscopy.bsky.social, is developing a new cutting-edge imaging technology: Selective Plane Illumination Lattice Light Sheet Microscopy.
🔗https://tinyurl.com/mu6xvpwc
🔗https://tinyurl.com/mu6xvpwc
📢Exciting opportunity for postdocs!
The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage.
Apply now: lnkd.in/eYkYUAhB
#FellowshipOpportunity #Postdoc #InterdisciplinaryResearch
@paediatrics.ox.ac.uk
The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage.
Apply now: lnkd.in/eYkYUAhB
#FellowshipOpportunity #Postdoc #InterdisciplinaryResearch
@paediatrics.ox.ac.uk
March 26, 2026 at 11:12 AM
📢Exciting opportunity for postdocs!
The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage.
Apply now: lnkd.in/eYkYUAhB
#FellowshipOpportunity #Postdoc #InterdisciplinaryResearch
@paediatrics.ox.ac.uk
The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage.
Apply now: lnkd.in/eYkYUAhB
#FellowshipOpportunity #Postdoc #InterdisciplinaryResearch
@paediatrics.ox.ac.uk
Congratulations to Filipa Simões and team on their new publication 👏
#regenerativemedicine #zebrafish #heart
#regenerativemedicine #zebrafish #heart
Excited to share our #preprint showing that #macrophages in the regenerating #zebrafish #heart are shaped by local cardiac-immune microniches, with a fibroblast-to-macrophage signal promoting regeneration over fibrotic repair www.biorxiv.org/content/10.6...
@idrm.ox.ac.uk @oxforddpag.bsky.social
@idrm.ox.ac.uk @oxforddpag.bsky.social
www.biorxiv.org
March 25, 2026 at 8:48 AM
Congratulations to Filipa Simões and team on their new publication 👏
#regenerativemedicine #zebrafish #heart
#regenerativemedicine #zebrafish #heart
Spring has arrived at the IDRM! As research in developmental biology and regenerative medicine pushes boundaries within IDRM's laboratories, our scientists can take a look outside and enjoy the view of the blossoming trees in our Japanese garden. 🌸 @ox.ac.uk
March 18, 2026 at 1:20 PM
Spring has arrived at the IDRM! As research in developmental biology and regenerative medicine pushes boundaries within IDRM's laboratories, our scientists can take a look outside and enjoy the view of the blossoming trees in our Japanese garden. 🌸 @ox.ac.uk
New research from the Roberts Group @ribomedicine.bsky.social at IDRM explores a new way to increase the body’s own production of BDNF, a key brain protein involved in neuron health, learning and memory.
Read the paper: tinyurl.com/ydwxk49d
Read the paper: tinyurl.com/ydwxk49d
March 10, 2026 at 1:42 PM
New research from the Roberts Group @ribomedicine.bsky.social at IDRM explores a new way to increase the body’s own production of BDNF, a key brain protein involved in neuron health, learning and memory.
Read the paper: tinyurl.com/ydwxk49d
Read the paper: tinyurl.com/ydwxk49d
Reposted by Institute of Developmental & Regenerative Medicine
What a pleasure to host @hsiuchuanlin.bsky.social @crg.eu to @idrm.ox.ac.uk @oxforddpag.bsky.social! We discussed in much depth novel technologies pushing forward the engineering human cell fate space- looking forward to exciting collaborations 🤩 And always a treat to visit @jesusoxford.bsky.social!
March 2, 2026 at 8:14 AM
What a pleasure to host @hsiuchuanlin.bsky.social @crg.eu to @idrm.ox.ac.uk @oxforddpag.bsky.social! We discussed in much depth novel technologies pushing forward the engineering human cell fate space- looking forward to exciting collaborations 🤩 And always a treat to visit @jesusoxford.bsky.social!
Spring has arrived at the IDRM just in time for Green Action Week! We are taking action by promoting our book swap, recycling, and Beauty Banks sustainable initiatives.
Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞
#GreenActionWeek #Sustainability
Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞
#GreenActionWeek #Sustainability
February 25, 2026 at 5:13 PM
Spring has arrived at the IDRM just in time for Green Action Week! We are taking action by promoting our book swap, recycling, and Beauty Banks sustainable initiatives.
Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞
#GreenActionWeek #Sustainability
Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞
#GreenActionWeek #Sustainability
International Women and Girls in Science Day 👩🔬✨
We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course.
Read more 👉 tinyurl.com/mrxurm52
We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course.
Read more 👉 tinyurl.com/mrxurm52
February 11, 2026 at 4:40 PM
International Women and Girls in Science Day 👩🔬✨
We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course.
Read more 👉 tinyurl.com/mrxurm52
We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course.
Read more 👉 tinyurl.com/mrxurm52
On #TimeToTalkDay, we’re proud to support open conversations about mental health. Will Vaulks, who recently gave a talk at the IDRM, and Prof Willem Kuyken remind us that sharing experiences can help reduce stigma around mental health challenges.
📽️ www.youtube.com/watch?v=8Hkd...
📽️ www.youtube.com/watch?v=8Hkd...
Time to talk
YouTube video by University of Oxford
www.youtube.com
February 5, 2026 at 5:59 PM
On #TimeToTalkDay, we’re proud to support open conversations about mental health. Will Vaulks, who recently gave a talk at the IDRM, and Prof Willem Kuyken remind us that sharing experiences can help reduce stigma around mental health challenges.
📽️ www.youtube.com/watch?v=8Hkd...
📽️ www.youtube.com/watch?v=8Hkd...
In December, we hosted the EMBO Lab Leadership Course with NDM and the Dunn School of Pathology.
We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams.
Read more: tinyurl.com/mrxurm52
We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams.
Read more: tinyurl.com/mrxurm52
January 16, 2026 at 3:15 PM
In December, we hosted the EMBO Lab Leadership Course with NDM and the Dunn School of Pathology.
We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams.
Read more: tinyurl.com/mrxurm52
We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams.
Read more: tinyurl.com/mrxurm52
This week’s scientific image, submitted by the Holländer Lab, is titled “The birth of immunity: spatial transcriptomics illuminating the thymus at E14.5.” The image uses spatial transcriptomics to visualise gene expression patterns across the embryonic thymus at day 14.5.
December 16, 2025 at 3:24 PM
This week’s scientific image, submitted by the Holländer Lab, is titled “The birth of immunity: spatial transcriptomics illuminating the thymus at E14.5.” The image uses spatial transcriptomics to visualise gene expression patterns across the embryonic thymus at day 14.5.
This week’s scientific image, created by Ehsan Razaghi, DPhil student, Simões lab, is titled “Immune-mediated spatial orchestration of cardiac regeneration in zebrafish, 5 days post cryoinjury.”
His research focuses on the role of the immune system in heart regeneration after myocardial infarction.
His research focuses on the role of the immune system in heart regeneration after myocardial infarction.
December 11, 2025 at 4:43 PM
This week’s scientific image, created by Ehsan Razaghi, DPhil student, Simões lab, is titled “Immune-mediated spatial orchestration of cardiac regeneration in zebrafish, 5 days post cryoinjury.”
His research focuses on the role of the immune system in heart regeneration after myocardial infarction.
His research focuses on the role of the immune system in heart regeneration after myocardial infarction.
A huge congratulations to Joe Day, former Communications & Operations Apprentice and current Business Development & Engagement Officer at the IDRM, on winning the Shining Star Apprentice Award at the 2025 University of Oxford Apprenticeship Awards!
December 10, 2025 at 3:02 PM
A huge congratulations to Joe Day, former Communications & Operations Apprentice and current Business Development & Engagement Officer at the IDRM, on winning the Shining Star Apprentice Award at the 2025 University of Oxford Apprenticeship Awards!
This week’s scientific image, contributed by Dr Emma Haberman from the Riley and Holländer groups, is titled “Atrial Architecture.” Her work investigates the role of T cell-mediated autoimmunity in the progression of heart failure after myocardial infarction.
December 4, 2025 at 4:24 PM
This week’s scientific image, contributed by Dr Emma Haberman from the Riley and Holländer groups, is titled “Atrial Architecture.” Her work investigates the role of T cell-mediated autoimmunity in the progression of heart failure after myocardial infarction.
New from Dr Matthew Stower and the Srinivas Group at IDRM 👇
Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos.
Read more: tinyurl.com/5999kkm8
Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos.
Read more: tinyurl.com/5999kkm8
November 28, 2025 at 2:39 PM
New from Dr Matthew Stower and the Srinivas Group at IDRM 👇
Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos.
Read more: tinyurl.com/5999kkm8
Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos.
Read more: tinyurl.com/5999kkm8
This week's scientific video, created by Dr Shifaan Thowfeequ from the Shankar Srinivas lab, is titled “Chasing the wave – in search of the origins of the first heartbeat.” The video captures the mechanical and chemical dynamics of an embryonic chick heart as it first forms and starts to beat.
November 27, 2025 at 3:33 PM
This week's scientific video, created by Dr Shifaan Thowfeequ from the Shankar Srinivas lab, is titled “Chasing the wave – in search of the origins of the first heartbeat.” The video captures the mechanical and chemical dynamics of an embryonic chick heart as it first forms and starts to beat.
Thanks to everyone who joined us for last week’s Get To Know Each Other event at the IDRM, and to all our fantastic speakers and poster presenters who made the afternoon such a success!
November 25, 2025 at 4:46 PM
Thanks to everyone who joined us for last week’s Get To Know Each Other event at the IDRM, and to all our fantastic speakers and poster presenters who made the afternoon such a success!
This week’s featured scientific image, "From blueprint to beating - engineering human cardiac development in a dish," comes from Selin Tüzüner (Simões Group), whose work was selected as a finalist in the BHF Reflections of Research competition.
Read more: lnkd.in/dQ4rZR9t
#ScientificImaging
Read more: lnkd.in/dQ4rZR9t
#ScientificImaging
November 20, 2025 at 6:01 PM
This week’s featured scientific image, "From blueprint to beating - engineering human cardiac development in a dish," comes from Selin Tüzüner (Simões Group), whose work was selected as a finalist in the BHF Reflections of Research competition.
Read more: lnkd.in/dQ4rZR9t
#ScientificImaging
Read more: lnkd.in/dQ4rZR9t
#ScientificImaging
✨ Monthly Featured Member ✨
Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career.
🔗Read more: shorturl.at/SWhc5
Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career.
🔗Read more: shorturl.at/SWhc5
November 19, 2025 at 4:57 PM
✨ Monthly Featured Member ✨
Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career.
🔗Read more: shorturl.at/SWhc5
Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career.
🔗Read more: shorturl.at/SWhc5