Kalli Kappel
@kallikappel.bsky.social
Assistant Professor at UCLA
HHMI Hanna Gray Faculty Fellow
PhD: Stanford Biophysics; Postdoc: Broad Institute
Excited about RNA+proteins+IDPs, high-throughput experiments+computation
HHMI Hanna Gray Faculty Fellow
PhD: Stanford Biophysics; Postdoc: Broad Institute
Excited about RNA+proteins+IDPs, high-throughput experiments+computation
Pinned
Kalli Kappel
@kallikappel.bsky.social
· Jun 17
Characterizing protein sequence determinants of nuclear condensates by high-throughput pooled imaging with CondenSeq
Nature Methods - CondenSeq is an imaging-based, high-throughput platform for characterizing condensate formation within the nuclear environment, uncovering the protein sequence features that...
rdcu.be
In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out!
rdcu.be/eq975
rdcu.be/eq975
Reposted by Kalli Kappel
Congratulations to Professor Kalli Kappel (@kallikappel.bsky.social) on receiving the 2026 UCLA Alpha Chi Sigma (ΑΧΣ) Glenn T. Seaborg Award!
www.chemistry.ucla.edu/news/2026-uc...
www.chemistry.ucla.edu/news/2026-uc...
June 26, 2026 at 12:08 AM
Congratulations to Professor Kalli Kappel (@kallikappel.bsky.social) on receiving the 2026 UCLA Alpha Chi Sigma (ΑΧΣ) Glenn T. Seaborg Award!
www.chemistry.ucla.edu/news/2026-uc...
www.chemistry.ucla.edu/news/2026-uc...
Reposted by Kalli Kappel
Roadtrip. For some, it might be vacation, for others it's a roadtrip from their postdoc to their new lab. I interviewed two scientists who kindly shared personal insight into what that feels like. And yes, they know that many are not having the good fortunate of landing a faculty job just yet. A 🧵
August 18, 2025 at 11:19 PM
Roadtrip. For some, it might be vacation, for others it's a roadtrip from their postdoc to their new lab. I interviewed two scientists who kindly shared personal insight into what that feels like. And yes, they know that many are not having the good fortunate of landing a faculty job just yet. A 🧵
Reposted by Kalli Kappel
How to spy on condensates: technology feature in
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
www.nature.com
June 27, 2025 at 5:30 PM
How to spy on condensates: technology feature in
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out!
rdcu.be/eq975
rdcu.be/eq975
Characterizing protein sequence determinants of nuclear condensates by high-throughput pooled imaging with CondenSeq
Nature Methods - CondenSeq is an imaging-based, high-throughput platform for characterizing condensate formation within the nuclear environment, uncovering the protein sequence features that...
rdcu.be
June 17, 2025 at 3:26 AM
In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out!
rdcu.be/eq975
rdcu.be/eq975