Kate Sears
@katesears.bsky.social
Hi I'm Kate, community lead for Open Medicine. We make expert medical knowledge easy to access so clinicians can offer the best treatment for their patients.
myopenmedicine.com
myopenmedicine.com
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Kate Sears
@katesears.bsky.social
· May 19
Hi friends,
Wanted to share our new company Open Medicine 🎉 🎉 🎉
Open Medicine is where leading doctors post Living Algorithms to share their expertise. Instead of static diagrams in PDFs, Living Algorithms are mobile-first, interactive and updated instantly as new clinical evidence emerges.
Wanted to share our new company Open Medicine 🎉 🎉 🎉
Open Medicine is where leading doctors post Living Algorithms to share their expertise. Instead of static diagrams in PDFs, Living Algorithms are mobile-first, interactive and updated instantly as new clinical evidence emerges.
Second relapse multiple myeloma from @vincentrk.bsky.social:
September 24, 2026 at 3:09 PM
Second relapse multiple myeloma from @vincentrk.bsky.social:
Treatment of Myeloma: First Relapse from @vincentrk.bsky.social:
September 23, 2026 at 3:45 PM
Treatment of Myeloma: First Relapse from @vincentrk.bsky.social:
Comprehensive thoracic solid tumor staging and treatment options algorithm from Prof. Andrea Bille at Guy's and St Thomas' NHS Trust: myopenmedicine.com/algorithms/c...
Comprehensive thoracic solid tumor staging and treatment options
Lung cancer management based on TNM staging, where early-stage (I–II) disease is primarily treated with surgical resection (with possible adjuvant therapy), while more advanced stages (III–IV) incorpo...
myopenmedicine.com
September 22, 2026 at 2:58 PM
Comprehensive thoracic solid tumor staging and treatment options algorithm from Prof. Andrea Bille at Guy's and St Thomas' NHS Trust: myopenmedicine.com/algorithms/c...
RET fusion–positive NSCLC: evolving adjuvant and metastatic targeted therapies from Dr. Gilberto Lopes at Sylvester Cancer Center: myopenmedicine.com/algorithms/r...
RET fusion–positive NSCLC: evolving adjuvant and metastatic targeted therapies
The metastatic portion is broadly aligned with current standards: comprehensive RET fusion testing at diagnosis and first-line selective RET inhibition (selpercatinib or pralsetinib) is guideline-conc...
myopenmedicine.com
September 21, 2026 at 3:45 PM
RET fusion–positive NSCLC: evolving adjuvant and metastatic targeted therapies from Dr. Gilberto Lopes at Sylvester Cancer Center: myopenmedicine.com/algorithms/r...
Universal Germline Genetic Testing in Prostate Cancer algorithm from Dr. Neal Shore at Atlantic Urology Clinics:
myopenmedicine.com/algorithms/u...
myopenmedicine.com/algorithms/u...
Universal Germline Genetic Testing in Prostate Cancer
myopenmedicine.com
September 18, 2026 at 2:40 PM
Universal Germline Genetic Testing in Prostate Cancer algorithm from Dr. Neal Shore at Atlantic Urology Clinics:
myopenmedicine.com/algorithms/u...
myopenmedicine.com/algorithms/u...
Low Risk and Favorable Intermediate Risk for Prostate Cancer algorithm from @tylersbrt.bsky.social: myopenmedicine.com/algorithms/l...
Low Risk and Favorable Intermediate Risk for Prostate Cancer
Selection and follow-up for men with low-risk and select favorable intermediate-risk prostate cancer. Tyler Seibert, MD, PhD, Genitourinary Section Chief at UC San Diego Radiation Oncology outlines cr...
myopenmedicine.com
September 17, 2026 at 2:46 PM
Low Risk and Favorable Intermediate Risk for Prostate Cancer algorithm from @tylersbrt.bsky.social: myopenmedicine.com/algorithms/l...
Surgery for thymic tumor algorithm from Prof. Andrea Bille at Guy's and St. Thomas' NHS Foundation Trust: myopenmedicine.com/algorithms/s...
Surgery for thymic tumour
Stage-based management of thymic tumors, emphasizing complete surgical resection (via VATS/RATS or open thymectomy) for early stages, with increasing need for en bloc resection of involved structures ...
myopenmedicine.com
September 16, 2026 at 2:31 PM
Surgery for thymic tumor algorithm from Prof. Andrea Bille at Guy's and St. Thomas' NHS Foundation Trust: myopenmedicine.com/algorithms/s...
IBCG Risk Stratification Model for Intermediate-Risk NMIBC algorithm from Dr. Ashish Kamat: myopenmedicine.com/algorithms/i...
IBCG Risk Stratification Model for Intermediate-Risk NMIBC
Intermediate-Risk Non–Muscle-Invasive Bladder Cancer (IR NMIBC) Risk Stratification Model by the International Bladder Cancer Group (IBCG).
myopenmedicine.com
September 15, 2026 at 2:29 PM
IBCG Risk Stratification Model for Intermediate-Risk NMIBC algorithm from Dr. Ashish Kamat: myopenmedicine.com/algorithms/i...
Newly Diagnosed Myeloma algorithm from @vincentrk.bsky.social: myopenmedicine.com/algorithms/n...
Newly Diagnosed Myeloma
Treatment algorithm for newly diagnosed myeloma patients. Dr. Rajkumar is a contributing editor to the International Myeloma Foundation (https://www.myeloma.org/frontline-treatment-options).Watch Dr....
myopenmedicine.com
September 14, 2026 at 2:36 PM
Newly Diagnosed Myeloma algorithm from @vincentrk.bsky.social: myopenmedicine.com/algorithms/n...
Gastric, Gastroesophageal Junction (GEJ) and Esophageal Adenocarcinoma algorithm from Dr. Yelena Janjigian at @mskcancercenter.bsky.social: myopenmedicine.com/algorithms/g...
Gastric, Gastroesophageal Junction (GEJ) and Esophageal Adenocarcinoma
Treatment algorithm for Gastric, Gastroesophageal Junction (GEJ) and Esophageal Adenocarcinoma by Yelena Y. Janjigian, MD, FASCO, Chief, Gastrointestinal Oncology Service at Memorial Sloan Kettering C...
myopenmedicine.com
September 11, 2026 at 2:39 PM
Gastric, Gastroesophageal Junction (GEJ) and Esophageal Adenocarcinoma algorithm from Dr. Yelena Janjigian at @mskcancercenter.bsky.social: myopenmedicine.com/algorithms/g...
Localized and metastatic primary malignant bone sarcoma algorithm from Dr. Michael Wagner at @mdanderson.bsky.social: myopenmedicine.com/algorithms/l...
Localized and metastatic primary malignant bone sarcoma
The algorithm is broadly aligned with contemporary management of primary malignant bone sarcomas: referral to a sarcoma center, histology-driven pathways, multimodality therapy for osteosarcoma and Ew...
myopenmedicine.com
September 10, 2026 at 2:30 PM
Localized and metastatic primary malignant bone sarcoma algorithm from Dr. Michael Wagner at @mdanderson.bsky.social: myopenmedicine.com/algorithms/l...
Molecular Testing for Pancreatic Cancer algorithm freom @mpishvaian.bsky.social: myopenmedicine.com/algorithms/m...
Molecular Testing for Pancreatic Cancer
Molecular testing for pancreatic cancer at first visit and within the first 2-4 weeks.
myopenmedicine.com
September 9, 2026 at 2:15 PM
Molecular Testing for Pancreatic Cancer algorithm freom @mpishvaian.bsky.social: myopenmedicine.com/algorithms/m...
Reposted by Kate Sears
Metastatic Triple-Negative Breast Cancer Treatment algorithm from Dr. Samantha El Warrak at Sylvester Cancer Center: myopenmedicine.com/algorithms/m...
Metastatic Triple-Negative Breast Cancer Treatment
myopenmedicine.com
September 8, 2026 at 2:32 PM
Metastatic Triple-Negative Breast Cancer Treatment algorithm from Dr. Samantha El Warrak at Sylvester Cancer Center: myopenmedicine.com/algorithms/m...
Stage I Testicular Germ Cell Tumors After Orchiectomy: Surveillance, Adjuvant Therapy, and Risk-Adapted Follow-Up algorithm from @drnataliagandur.bsky.social: myopenmedicine.com/algorithms/s...
Stage I Testicular Germ Cell Tumors After Orchiectomy: Surveillance, Adjuvant Therapy, and Risk-Adapted Follow-Up
This algorithm is broadly aligned with contemporary stage I testicular GCT management: confirm true clinical stage I with appropriate post-orchiectomy marker kinetics and imaging, then select surveill...
myopenmedicine.com
September 4, 2026 at 2:52 PM
Stage I Testicular Germ Cell Tumors After Orchiectomy: Surveillance, Adjuvant Therapy, and Risk-Adapted Follow-Up algorithm from @drnataliagandur.bsky.social: myopenmedicine.com/algorithms/s...
Stage I–III Non-Small Cell Lung Cancer Treatment algorithm from @janichinmay.bsky.social and Dr. Gilberto Lopes: myopenmedicine.com/algorithms/s...
Stage I–III Non-Small Cell Lung Cancer Treatment
The algorithm is broadly aligned with current management of stage I–IIIB NSCLC: guideline-concordant diagnostic workup, surgery or SBRT for early-stage disease, biomarker-driven adjuvant targeted ther...
myopenmedicine.com
September 3, 2026 at 3:00 PM
Stage I–III Non-Small Cell Lung Cancer Treatment algorithm from @janichinmay.bsky.social and Dr. Gilberto Lopes: myopenmedicine.com/algorithms/s...
Management of Platinum-Sensitive Recurrent Ovarian Cancer algorithm from @drkatymoore.bsky.social: myopenmedicine.com/algorithms/m...
Management of Platinum-Sensitive Recurrent Ovarian Cancer
The algorithm is broadly aligned with contemporary management of platinum-sensitive recurrent epithelial ovarian cancer: use of platinum-based combinations, consideration of secondary cytoreductive su...
myopenmedicine.com
September 2, 2026 at 3:50 PM
Management of Platinum-Sensitive Recurrent Ovarian Cancer algorithm from @drkatymoore.bsky.social: myopenmedicine.com/algorithms/m...
Belzutifan Practical Guidance in Advanced Clear-Cell RCC algorithm from @drchoueiri.bsky.social: myopenmedicine.com/algorithms/b...
Belzutifan Practical Guidance in Advanced Clear-Cell RCC
This belzutifan-focused pathway is broadly aligned with current evidence and labeling for advanced/metastatic ccRCC after prior PD-(L)1 inhibitor and VEGF-targeted therapy, centering on LITESPARK-005 ...
myopenmedicine.com
September 1, 2026 at 3:18 PM
Belzutifan Practical Guidance in Advanced Clear-Cell RCC algorithm from @drchoueiri.bsky.social: myopenmedicine.com/algorithms/b...
TALAPRO-2: Talazoparib + Enzalutamide in HRR-Altered First-Line mCRPC algorithm from @neerajagarwal.bsky.social: myopenmedicine.com/algorithms/t...
TALAPRO-2: Talazoparib + Enzalutamide in HRR-Altered First-Line mCRPC
The algorithm is broadly aligned with contemporary mCRPC management: maintain ADT, perform HRR (germline/somatic) testing early, and consider PARP inhibitor combinations for HRR-altered disease. Place...
myopenmedicine.com
August 31, 2026 at 3:27 PM
TALAPRO-2: Talazoparib + Enzalutamide in HRR-Altered First-Line mCRPC algorithm from @neerajagarwal.bsky.social: myopenmedicine.com/algorithms/t...
Early and Advanced Triple Negative Breast Cancer (TNBC) from @ilanaschlam.bsky.social: myopenmedicine.com/algorithms/e...
Early and Advanced Triple Negative Breast Cancer (TNBC)
The algorithm is broadly aligned with contemporary TNBC practice: neoadjuvant pembrolizumab plus chemotherapy for high-risk early TNBC; adjuvant escalation strategies for residual disease including ca...
myopenmedicine.com
August 27, 2026 at 3:23 PM
Early and Advanced Triple Negative Breast Cancer (TNBC) from @ilanaschlam.bsky.social: myopenmedicine.com/algorithms/e...
TALAPRO-3: Talazoparib + Enzalutamide + ADT in HRR-Altered mCSPC from @neerajagarwal.bsky.social: myopenmedicine.com/algorithms/t...
TALAPRO-3: Talazoparib + Enzalutamide + ADT in HRR-Altered mCSPC
The algorithm is broadly aligned with current mCSPC practice in emphasizing ADT as backbone therapy, recommending treatment intensification, and incorporating germline/somatic testing to guide therapy...
myopenmedicine.com
August 26, 2026 at 3:15 PM
TALAPRO-3: Talazoparib + Enzalutamide + ADT in HRR-Altered mCSPC from @neerajagarwal.bsky.social: myopenmedicine.com/algorithms/t...
PSMA-Positive mHSPC: Integrating Lu-177 Vipivotide Tetraxetan With ADT + ARPI algorithm from Prof. Arun Azad: myopenmedicine.com/algorithms/p...
PSMA-Positive mHSPC: Integrating Lu-177 Vipivotide Tetraxetan With ADT + ARPI
myopenmedicine.com
August 25, 2026 at 2:41 PM
PSMA-Positive mHSPC: Integrating Lu-177 Vipivotide Tetraxetan With ADT + ARPI algorithm from Prof. Arun Azad: myopenmedicine.com/algorithms/p...
Newly Diagnosed Myeloma from @vincentrk.bsky.social: myopenmedicine.com/algorithms/n...
Newly Diagnosed Myeloma
Treatment algorithm for newly diagnosed myeloma patients. Dr. Rajkumar is a contributing editor to the International Myeloma Foundation (https://www.myeloma.org/frontline-treatment-options).
myopenmedicine.com
August 24, 2026 at 2:37 PM
Newly Diagnosed Myeloma from @vincentrk.bsky.social: myopenmedicine.com/algorithms/n...
Primary Plasma Cell Leukemia algorithm from Dr. Samer Al Hadidi: myopenmedicine.com/algorithms/p...
Primary Plasma Cell Leukemia
myopenmedicine.com
July 29, 2026 at 4:41 PM
Primary Plasma Cell Leukemia algorithm from Dr. Samer Al Hadidi: myopenmedicine.com/algorithms/p...