Marisa Isabell Keller
@maelschermarisa.bsky.social
Postdoc | she/her | Hansen group | University Copenhagen | Bork group alumna
Scientist decoding the Human and Microbiome Relationship via Computational Biology 👩💻
A lover of music 🎶🎷 and the call of the wild 🌿🏔️
Scientist decoding the Human and Microbiome Relationship via Computational Biology 👩💻
A lover of music 🎶🎷 and the call of the wild 🌿🏔️
“The databases he built and the community he nurtured have enabled discoveries by countless researchers who may never have encountered his papers directly but whose work rests on the infrastructure he created.”
🧬🕊️
🧬🕊️
From @alexbateman1.bsky.social in #OUP 's @bioinfoadv.bsky.social journal | Peer Bork (1963-2026): pioneer of #ComputationalBiology, architect of #Bioinformatics #Resources, and visionary #Microbiome researcher | #OpenScience CC/ @embl.org @ebi.embl.org | 🧬🖥️🧪🔓❤️
⬇️
academic.oup.com/bioinformati...
⬇️
academic.oup.com/bioinformati...
Peer Bork (1963–2026): pioneer of computational biology, architect of bioinformatics resources, and visionary microbiome researcher
Peer Bork, one of the most influential computational biologists of his generation, died on 16 January 2026 from natural causes (EMBL 2026). He was 62 years
academic.oup.com
October 13, 2026 at 7:47 AM
“The databases he built and the community he nurtured have enabled discoveries by countless researchers who may never have encountered his papers directly but whose work rests on the infrastructure he created.”
🧬🕊️
🧬🕊️
Thank you for this wonderful week!
Now, my brain is filled with statistics and math 🤯. It will take some time to digest and apply what I have learned, but I am looking forward to challenge my data. 📊
Now, my brain is filled with statistics and math 🤯. It will take some time to digest and apply what I have learned, but I am looking forward to challenge my data. 📊
Thank you to all of our delegates and trainers involved in this week's @embo.org Practical Course.
Interested in future training courses with EMBL-EBI Training? View our 2027 programme and find an event that suits you: www.ebi.ac.uk/training/liv...
@ebi.embl.org
@events.embl.org
🧬🖥️📊
Interested in future training courses with EMBL-EBI Training? View our 2027 programme and find an event that suits you: www.ebi.ac.uk/training/liv...
@ebi.embl.org
@events.embl.org
🧬🖥️📊
October 9, 2026 at 6:58 PM
Thank you for this wonderful week!
Now, my brain is filled with statistics and math 🤯. It will take some time to digest and apply what I have learned, but I am looking forward to challenge my data. 📊
Now, my brain is filled with statistics and math 🤯. It will take some time to digest and apply what I have learned, but I am looking forward to challenge my data. 📊
Reposted by Marisa Isabell Keller
At the start of 2026, EMBL lost long-serving colleague and Interim Director General Peer Bork. Join us in commemorating Peer and his legacy at the #EMBLBorkMemorial.
Submit your abstract by 10 November: s.embl.org/pbs27-01-bl
Submit your abstract by 10 November: s.embl.org/pbs27-01-bl
September 7, 2026 at 12:29 PM
At the start of 2026, EMBL lost long-serving colleague and Interim Director General Peer Bork. Join us in commemorating Peer and his legacy at the #EMBLBorkMemorial.
Submit your abstract by 10 November: s.embl.org/pbs27-01-bl
Submit your abstract by 10 November: s.embl.org/pbs27-01-bl
Deadline extended to August 24th! ⬇️
2-year international postdoc position available in Copenhagen!
If you are interested in multi-omics, have a background in computational biology and a PhD from outside Denmark, check out this position about the oral-liver axis.
Deadline 10th of August.
employment.ku.dk/all-vacancie...
If you are interested in multi-omics, have a background in computational biology and a PhD from outside Denmark, check out this position about the oral-liver axis.
Deadline 10th of August.
employment.ku.dk/all-vacancie...
Postdoc in Deciphering the Oral–Liver Axis: Integrative Cross-Organ Multi-Omics Analysis
employment.ku.dk
August 11, 2026 at 8:20 PM
Deadline extended to August 24th! ⬇️
2-year international postdoc position available in Copenhagen!
If you are interested in multi-omics, have a background in computational biology and a PhD from outside Denmark, check out this position about the oral-liver axis.
Deadline 10th of August.
employment.ku.dk/all-vacancie...
If you are interested in multi-omics, have a background in computational biology and a PhD from outside Denmark, check out this position about the oral-liver axis.
Deadline 10th of August.
employment.ku.dk/all-vacancie...
Postdoc in Deciphering the Oral–Liver Axis: Integrative Cross-Organ Multi-Omics Analysis
employment.ku.dk
July 14, 2026 at 12:06 PM
2-year international postdoc position available in Copenhagen!
If you are interested in multi-omics, have a background in computational biology and a PhD from outside Denmark, check out this position about the oral-liver axis.
Deadline 10th of August.
employment.ku.dk/all-vacancie...
If you are interested in multi-omics, have a background in computational biology and a PhD from outside Denmark, check out this position about the oral-liver axis.
Deadline 10th of August.
employment.ku.dk/all-vacancie...
Happening today!
Please join the Symbiosis Alumni Network during our next seminar with talks by Rowan Hart and Naama Geva-Zatorsky
🗓️ June 24th
🕥 4pm WEST
📍register on gimm.idloom.events/symbnet_semi... for link
@naamagz.bsky.social
@symbnet.bsky.social
@moorefound.bsky.social
@mblscience.bsky.social
ECODIM
🗓️ June 24th
🕥 4pm WEST
📍register on gimm.idloom.events/symbnet_semi... for link
@naamagz.bsky.social
@symbnet.bsky.social
@moorefound.bsky.social
@mblscience.bsky.social
ECODIM
June 24, 2026 at 8:10 AM
Happening today!
Reposted by Marisa Isabell Keller
New in @natgenet.nature.com: a moving obituary for Peer.
Francesca Ciccarelli, Jan Korbel & Christian von Mering reflect on his scientific vision, from protein domains and genome evolution to metagenomics, and on his generosity as a mentor and friend to so many.
www.nature.com/articles/s41...
Francesca Ciccarelli, Jan Korbel & Christian von Mering reflect on his scientific vision, from protein domains and genome evolution to metagenomics, and on his generosity as a mentor and friend to so many.
www.nature.com/articles/s41...
Peer Bork (1963–2026) - Nature Genetics
Nature Genetics - Peer Bork (1963–2026)
www.nature.com
June 1, 2026 at 11:51 AM
New in @natgenet.nature.com: a moving obituary for Peer.
Francesca Ciccarelli, Jan Korbel & Christian von Mering reflect on his scientific vision, from protein domains and genome evolution to metagenomics, and on his generosity as a mentor and friend to so many.
www.nature.com/articles/s41...
Francesca Ciccarelli, Jan Korbel & Christian von Mering reflect on his scientific vision, from protein domains and genome evolution to metagenomics, and on his generosity as a mentor and friend to so many.
www.nature.com/articles/s41...
@borklab.bsky.social @embl.org @biocs.bsky.social @cbmr.science @aleksanderkrag.bsky.social @podlesny.bsky.social @suguru-nishijima.bsky.social @fullam.bsky.social @chanyeong-kim.bsky.social @israelsenm.bsky.social and many other not on Bluesky!
June 1, 2026 at 11:31 AM
We then identified the microbial taxa that are relevant for bile acid metabolism by mapping the relevant genes and transcripts onto the metagenome-assembled genomes (MAGs) derived from the study cohort and compared their abundance and prevalence in ALD and healthy subjects.
June 1, 2026 at 11:31 AM
We then identified the microbial taxa that are relevant for bile acid metabolism by mapping the relevant genes and transcripts onto the metagenome-assembled genomes (MAGs) derived from the study cohort and compared their abundance and prevalence in ALD and healthy subjects.
ALD causes half of all liver-related deaths worldwide. We asked: what happens to the communication between liver and gut as the disease progresses?
We found that hepatic bile acid synthesis and the transport back to the liver are disrupted, leading to the accumulation of bile acids at toxic levels.
We found that hepatic bile acid synthesis and the transport back to the liver are disrupted, leading to the accumulation of bile acids at toxic levels.
June 1, 2026 at 11:31 AM
ALD causes half of all liver-related deaths worldwide. We asked: what happens to the communication between liver and gut as the disease progresses?
We found that hepatic bile acid synthesis and the transport back to the liver are disrupted, leading to the accumulation of bile acids at toxic levels.
We found that hepatic bile acid synthesis and the transport back to the liver are disrupted, leading to the accumulation of bile acids at toxic levels.
Our work exploring host-microbial co-metabolism of bile acids in patients with alcohol-related liver disease (ALD) has been published in the JHEP Reports:
www.sciencedirect.com/science/arti...
🪐 A big thank you to everyone involved, to the GALAXY and MicrobLiver consortia who made this possible! 🙌
www.sciencedirect.com/science/arti...
🪐 A big thank you to everyone involved, to the GALAXY and MicrobLiver consortia who made this possible! 🙌
Alcohol-related liver disease disrupts bile acid homeostasis and gut microbial bile acid metabolism
Alcohol overuse disrupts liver function and alters gut microbial communities, with alcohol-related liver disease (ALD) causing half of all liver-relat…
www.sciencedirect.com
June 1, 2026 at 11:31 AM
Our work exploring host-microbial co-metabolism of bile acids in patients with alcohol-related liver disease (ALD) has been published in the JHEP Reports:
www.sciencedirect.com/science/arti...
🪐 A big thank you to everyone involved, to the GALAXY and MicrobLiver consortia who made this possible! 🙌
www.sciencedirect.com/science/arti...
🪐 A big thank you to everyone involved, to the GALAXY and MicrobLiver consortia who made this possible! 🙌
Nine members of the Hansen group at the @cbmr.science Novo Nordisk Foundation Center for Basic Metabolic Research will be participating in the Study Group on Genetics of Diabetes (SGDD) conference this week!
If you are attending as well, we would love to meet you at our talks and posters! 🧬
If you are attending as well, we would love to meet you at our talks and posters! 🧬
May 5, 2026 at 2:04 PM
Nine members of the Hansen group at the @cbmr.science Novo Nordisk Foundation Center for Basic Metabolic Research will be participating in the Study Group on Genetics of Diabetes (SGDD) conference this week!
If you are attending as well, we would love to meet you at our talks and posters! 🧬
If you are attending as well, we would love to meet you at our talks and posters! 🧬
Reposted by Marisa Isabell Keller
Join us Wednesday, 29th April, at 4pm WEST (Lisbon time), for two Symbiosis Alumni Seminars by @omaistrenko.bsky.social and @pawley.bsky.social.
Zoom link upon free registration at gimm.idloom.events/symbnet_semi...
@symbnet.bsky.social, @moorefound.bsky.social, @mblscience.bsky.social, ECODIM
Zoom link upon free registration at gimm.idloom.events/symbnet_semi...
@symbnet.bsky.social, @moorefound.bsky.social, @mblscience.bsky.social, ECODIM
April 27, 2026 at 2:04 PM
Join us Wednesday, 29th April, at 4pm WEST (Lisbon time), for two Symbiosis Alumni Seminars by @omaistrenko.bsky.social and @pawley.bsky.social.
Zoom link upon free registration at gimm.idloom.events/symbnet_semi...
@symbnet.bsky.social, @moorefound.bsky.social, @mblscience.bsky.social, ECODIM
Zoom link upon free registration at gimm.idloom.events/symbnet_semi...
@symbnet.bsky.social, @moorefound.bsky.social, @mblscience.bsky.social, ECODIM
As always, "science stands on the shoulders of giants". I am grateful for all the work that others have done before me, enabling me to conduct this research using the valuable datasets available to me.
March 5, 2026 at 6:44 AM
As always, "science stands on the shoulders of giants". I am grateful for all the work that others have done before me, enabling me to conduct this research using the valuable datasets available to me.
I want to share this news here because I am really happy about it. 🥳
This is definitely a dream come true!
👩🏼💻🧬🦠
.. and a lot of work ahead.
dhttps://shorturl.at/bOwae
This is definitely a dream come true!
👩🏼💻🧬🦠
.. and a lot of work ahead.
dhttps://shorturl.at/bOwae
CBMR Postdocs Marisa Isabell Keller (Hansen Group) and Scott Frendo-Cumbo (Zierath Group) have both secured MSCA Postdoctoral Fellowships!
Marisa’s project, ARCTIC, aims to identify diagnostic and… |...
CBMR Postdocs Marisa Isabell Keller (Hansen Group) and Scott Frendo-Cumbo (Zierath Group) have both secured MSCA Postdoctoral Fellowships!
Marisa’s project, ARCTIC, aims to identify diagnostic and pr...
shorturl.at
March 5, 2026 at 6:44 AM
I want to share this news here because I am really happy about it. 🥳
This is definitely a dream come true!
👩🏼💻🧬🦠
.. and a lot of work ahead.
dhttps://shorturl.at/bOwae
This is definitely a dream come true!
👩🏼💻🧬🦠
.. and a lot of work ahead.
dhttps://shorturl.at/bOwae
Reposted by Marisa Isabell Keller
It has been two weeks since the unexpected death of Peer Bork, and all of us in his research group are deeply missing him. His scientific vision brought us together as a team, and we are immensely grateful for the time we spent together. 🧵
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.
We extend our deepest condolences to his family, friends, and colleagues.
www.embl.org/news/people-...
We extend our deepest condolences to his family, friends, and colleagues.
www.embl.org/news/people-...
January 30, 2026 at 3:05 PM
It has been two weeks since the unexpected death of Peer Bork, and all of us in his research group are deeply missing him. His scientific vision brought us together as a team, and we are immensely grateful for the time we spent together. 🧵
Thank you, Lars. Your words sum up Peer and the void he leaves behind perfectly.🥺
In memory of Peer Bork, who sadly passed away yesterday.
@embl.org @borklab.bsky.social
youtube.com/shorts/ymqyM...
@embl.org @borklab.bsky.social
youtube.com/shorts/ymqyM...
January 18, 2026 at 9:34 AM
Thank you, Lars. Your words sum up Peer and the void he leaves behind perfectly.🥺
Very sad and shocking news. This is way to early. Peer had still so many big plans.
As he was not only EMBL director and a great scientist but also my PhD supervisor, it feels that part of my scientific identity was dragged with im.
RIP.
In remembrance of Peer Bork www.embl.org/news/embl-an...
As he was not only EMBL director and a great scientist but also my PhD supervisor, it feels that part of my scientific identity was dragged with im.
RIP.
In remembrance of Peer Bork www.embl.org/news/embl-an...
In remembrance of Peer Bork | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
www.embl.org
January 17, 2026 at 6:52 AM
Very sad and shocking news. This is way to early. Peer had still so many big plans.
As he was not only EMBL director and a great scientist but also my PhD supervisor, it feels that part of my scientific identity was dragged with im.
RIP.
In remembrance of Peer Bork www.embl.org/news/embl-an...
As he was not only EMBL director and a great scientist but also my PhD supervisor, it feels that part of my scientific identity was dragged with im.
RIP.
In remembrance of Peer Bork www.embl.org/news/embl-an...
Reposted by Marisa Isabell Keller
Professor Bosch and @crc1182.bsky.social are an inspiration that decisively revealed an ancient, elemental unity of life between the animal and microbial worlds. More importantly, he will stand as a giant that many, including me, have stood on to go farther. www.psu.edu/news/huck-in...
Host-microbiome interaction biologist to receive inaugural Microbiome Medal | Penn State University
The One Health Microbiome Center will present the inaugural Microbiome Medal to Thomas Bosch on Dec 12. Bosch, a developmental biologist, zoologist and distinguished senior professor at Kiel Universit...
www.psu.edu
December 15, 2025 at 8:50 PM
Professor Bosch and @crc1182.bsky.social are an inspiration that decisively revealed an ancient, elemental unity of life between the animal and microbial worlds. More importantly, he will stand as a giant that many, including me, have stood on to go farther. www.psu.edu/news/huck-in...
Reposted by Marisa Isabell Keller
Great to see this finally published!
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
Abstract. Metagenomic sequencing enables the in-depth study of microbes and their functions in humans, animals, and the environment. While sequencing data
academic.oup.com
October 31, 2025 at 3:16 PM
Great to see this finally published!
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Reposted by Marisa Isabell Keller
Finding microbes in cancer sequencing data has been controversial. Are we seeing real biology… or just contamination + batch effects?
September 3, 2025 at 7:00 PM
Finding microbes in cancer sequencing data has been controversial. Are we seeing real biology… or just contamination + batch effects?
Reposted by Marisa Isabell Keller
We're still not finding any good evidence for a microbiome in any cancer type: see our new paper in @ScienceTM led by PhD student Yuchen (Peter) Ge www.science.org/doi/10.1126/... and the accompanying news piece, www.science.org/content/arti...
Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project
An analysis of TCGA whole-genome sequencing samples yields a comprehensive resource for investigating the role of microbes in cancer.
www.science.org
September 3, 2025 at 8:45 PM
We're still not finding any good evidence for a microbiome in any cancer type: see our new paper in @ScienceTM led by PhD student Yuchen (Peter) Ge www.science.org/doi/10.1126/... and the accompanying news piece, www.science.org/content/arti...
Reposted by Marisa Isabell Keller
We're very happy to release our new database Metalog metalog.embl.de ! It offers manually curated and harmonised contextual data for 110k metagenomics samples across the globe, incl. precomputed taxonomic profiles, for interactive browsing and for download 🧵 1/7
#microsky
#microsky
Metalog
Metalog is a repository of manually annotated metadata (or contextual data) for metagenomic sequencing data from across the globe.
metalog.embl.de
August 15, 2025 at 8:07 AM
We're very happy to release our new database Metalog metalog.embl.de ! It offers manually curated and harmonised contextual data for 110k metagenomics samples across the globe, incl. precomputed taxonomic profiles, for interactive browsing and for download 🧵 1/7
#microsky
#microsky
Reposted by Marisa Isabell Keller
Symbnet PhD Summer School on Host-Microbe Symbioses - Oeiras Portugal. Students from all over the world are eligible, we sponsor selected students. Please Repost!
gimm.idloom.events/phd-summer-s...
gimm.idloom.events/phd-summer-s...
PhD Summer School on Host-Microbe Symbioses 2025
Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...
gimm.idloom.events
March 16, 2025 at 12:26 PM
Symbnet PhD Summer School on Host-Microbe Symbioses - Oeiras Portugal. Students from all over the world are eligible, we sponsor selected students. Please Repost!
gimm.idloom.events/phd-summer-s...
gimm.idloom.events/phd-summer-s...
Reposted by Marisa Isabell Keller
🚀 7th GA #Meeting in Cologne, Germany from 27-29 January 2025! A huge thank you to everyone for sharing their latest results and project updates! 👏
And of course, we wrapped it up with some after-work fun, exploring Cologne with a @sciencerallye.bsky.social! 🏙️ ⛲
And of course, we wrapped it up with some after-work fun, exploring Cologne with a @sciencerallye.bsky.social! 🏙️ ⛲
February 17, 2025 at 10:00 AM
🚀 7th GA #Meeting in Cologne, Germany from 27-29 January 2025! A huge thank you to everyone for sharing their latest results and project updates! 👏
And of course, we wrapped it up with some after-work fun, exploring Cologne with a @sciencerallye.bsky.social! 🏙️ ⛲
And of course, we wrapped it up with some after-work fun, exploring Cologne with a @sciencerallye.bsky.social! 🏙️ ⛲