Centre for Mechanochemical Cell Biology
@mechanochemistry.org
Interdisciplinary research centre at the University of Warwick (UK) with the mission to understand active self-organisation of living systems with a focus on molecular machines, cellular interfaces and tissue mechanobiology
Reposted by Centre for Mechanochemical Cell Biology
NEWS: @anne.mechanochemistry.org and I are the new Joint Directors of the Centre for Mechanochemical Cell Biology (CMCB) at Warwick @mechanochemistry.org
We thank @rob.mechanochemistry.org who has been at the helm of CMCB since its inception. Looking forward to more exciting science in the future.
We thank @rob.mechanochemistry.org who has been at the helm of CMCB since its inception. Looking forward to more exciting science in the future.
September 4, 2026 at 1:47 PM
NEWS: @anne.mechanochemistry.org and I are the new Joint Directors of the Centre for Mechanochemical Cell Biology (CMCB) at Warwick @mechanochemistry.org
We thank @rob.mechanochemistry.org who has been at the helm of CMCB since its inception. Looking forward to more exciting science in the future.
We thank @rob.mechanochemistry.org who has been at the helm of CMCB since its inception. Looking forward to more exciting science in the future.
10 years Bowman lab @bowchro.bsky.social anniversary today, so we are treated to a complete history with all side bets talk. Congratulations 🎉
June 9, 2026 at 1:04 PM
10 years Bowman lab @bowchro.bsky.social anniversary today, so we are treated to a complete history with all side bets talk. Congratulations 🎉
Reposted by Centre for Mechanochemical Cell Biology
A mystery at @mechanochemistry.org !
There’s a carrot that is neatly placed in the corridor. None is admitting to owning it. How did it get here? Where will it go next? 🥕
There’s a carrot that is neatly placed in the corridor. None is admitting to owning it. How did it get here? Where will it go next? 🥕
May 18, 2026 at 11:16 AM
A mystery at @mechanochemistry.org !
There’s a carrot that is neatly placed in the corridor. None is admitting to owning it. How did it get here? Where will it go next? 🥕
There’s a carrot that is neatly placed in the corridor. None is admitting to owning it. How did it get here? Where will it go next? 🥕
Reposted by Centre for Mechanochemical Cell Biology
We had a blast. Thanks to everyone who came and made this such a memorable event.
May 9, 2026 at 8:53 PM
We had a blast. Thanks to everyone who came and made this such a memorable event.
Last but not least, Kristen Verhey's @kjverhey1.bsky.social closing keynote. She starts off with her top 5 of Rob's papers over the years
May 9, 2026 at 10:55 AM
Last but not least, Kristen Verhey's @kjverhey1.bsky.social closing keynote. She starts off with her top 5 of Rob's papers over the years
Erik Schäffer @schaefferlab.bsky.social uses silicon nanospheres to measure the forces of ultra-weak plant kinesins with sub femtoNewton resolution.
May 9, 2026 at 10:41 AM
Erik Schäffer @schaefferlab.bsky.social uses silicon nanospheres to measure the forces of ultra-weak plant kinesins with sub femtoNewton resolution.
Mark Dodding @markdodding.bsky.social talks about cargo-dependent activation of kinesin-1 through the light chain. Phosphorylation by NEK10 kinase suppresses membrane association of KLC2 specifically and controls lysosome transport by cooperation with cargo adapters.
May 9, 2026 at 10:16 AM
Mark Dodding @markdodding.bsky.social talks about cargo-dependent activation of kinesin-1 through the light chain. Phosphorylation by NEK10 kinase suppresses membrane association of KLC2 specifically and controls lysosome transport by cooperation with cargo adapters.
Our own Masanori Mishima is up next discussing weak electrostatic interactions of motors and tracks that can be regulated by post translational modifications with examples from phosphorylation of KIF23/MKLP1 and arginylation and myosin II.
May 9, 2026 at 9:25 AM
Our own Masanori Mishima is up next discussing weak electrostatic interactions of motors and tracks that can be regulated by post translational modifications with examples from phosphorylation of KIF23/MKLP1 and arginylation and myosin II.
Varun Ramaswamy is describing how he tackled the difficult problem of determining the structure of full length of HSET
May 9, 2026 at 9:04 AM
Varun Ramaswamy is describing how he tackled the difficult problem of determining the structure of full length of HSET
Reposted by Centre for Mechanochemical Cell Biology
What happens when science is free to ask any question?
It leads to discoveries we didn’t plan for – but now depend on.
This #EuropeDay, we support #ProtectWhatMatters, celebrating the freedom that makes frontier research possible.
Read the stories 👉 buff.ly/SRCDWoW
and have a happy Europe Day! 🇪🇺
It leads to discoveries we didn’t plan for – but now depend on.
This #EuropeDay, we support #ProtectWhatMatters, celebrating the freedom that makes frontier research possible.
Read the stories 👉 buff.ly/SRCDWoW
and have a happy Europe Day! 🇪🇺
May 9, 2026 at 8:00 AM
What happens when science is free to ask any question?
It leads to discoveries we didn’t plan for – but now depend on.
This #EuropeDay, we support #ProtectWhatMatters, celebrating the freedom that makes frontier research possible.
Read the stories 👉 buff.ly/SRCDWoW
and have a happy Europe Day! 🇪🇺
It leads to discoveries we didn’t plan for – but now depend on.
This #EuropeDay, we support #ProtectWhatMatters, celebrating the freedom that makes frontier research possible.
Read the stories 👉 buff.ly/SRCDWoW
and have a happy Europe Day! 🇪🇺
Starting off today is Marija Zanic @zaniclab.bsky.social who introduces us to SSNA1, a sensor for microtubule damage and microtubule stabiliser, that increases their rigidity and protects against breakage
May 9, 2026 at 8:47 AM
Starting off today is Marija Zanic @zaniclab.bsky.social who introduces us to SSNA1, a sensor for microtubule damage and microtubule stabiliser, that increases their rigidity and protects against breakage
Good morning! Day 2 of our Motors and Filaments meeting is under way.
May 9, 2026 at 8:37 AM
Good morning! Day 2 of our Motors and Filaments meeting is under way.
Dinner impressions. Now everyone really knackered after a quiz that felt more like an exam on physical biology of the cytoskeleton. Getting very competitive during the marking process...
May 8, 2026 at 8:14 PM
Dinner impressions. Now everyone really knackered after a quiz that felt more like an exam on physical biology of the cytoskeleton. Getting very competitive during the marking process...
The "Vanderbilt girls" on the way to the dinner in the Tocil Wood bluebells.
May 8, 2026 at 7:40 PM
The "Vanderbilt girls" on the way to the dinner in the Tocil Wood bluebells.
Evening keynote from Rob Cross summarising 35 years of research to understand how kinesin walks along microtubules featuring the neck linker as position sensor, the load-dependence of dwell time and directionality of steps and the type of microtubule track.
May 8, 2026 at 4:47 PM
Evening keynote from Rob Cross summarising 35 years of research to understand how kinesin walks along microtubules featuring the neck linker as position sensor, the load-dependence of dwell time and directionality of steps and the type of microtubule track.
Yean-Ming (Cross lab) talks about the dynamics of different tubulin isotypes and interrogates the lateral interaction regions, generating a chimera that assembled so readily that they also assemble in GDP.
May 8, 2026 at 4:20 PM
Yean-Ming (Cross lab) talks about the dynamics of different tubulin isotypes and interrogates the lateral interaction regions, generating a chimera that assembled so readily that they also assemble in GDP.
Reposted by Centre for Mechanochemical Cell Biology
Some poster session impressions from motors and filaments meeting
May 8, 2026 at 3:43 PM
Some poster session impressions from motors and filaments meeting
Glenn Carrington (Peckham lab) shows the structure of myosin-5 in a two head bound state on actin and highlights strain-associated changes in the motor domain that explains different ADP release rates from leading and trailing heads.
May 8, 2026 at 3:03 PM
Glenn Carrington (Peckham lab) shows the structure of myosin-5 in a two head bound state on actin and highlights strain-associated changes in the motor domain that explains different ADP release rates from leading and trailing heads.
Some happy faces behind the scenes - this is a reunion of @joehowardd.bsky.social with his former diploma student Frauke Hussmann
May 8, 2026 at 2:45 PM
Some happy faces behind the scenes - this is a reunion of @joehowardd.bsky.social with his former diploma student Frauke Hussmann
Beth Lawrence (Manchester) talks about her postdoc project in the @zaniclab.bsky.social where she showed that human CLASP2 promotes rescues and suppresses catastrophies without affecting microtubule assembly and disassembly speeds. CLASP can convert the pre-catastrophe intermediate state to growth
May 8, 2026 at 2:37 PM
Beth Lawrence (Manchester) talks about her postdoc project in the @zaniclab.bsky.social where she showed that human CLASP2 promotes rescues and suppresses catastrophies without affecting microtubule assembly and disassembly speeds. CLASP can convert the pre-catastrophe intermediate state to growth
Jingyi Luo (Ti lab) identifies a single amino acid change in beta3-tubulin that can sensitise cancer cells to paclitaxel by allosteric changes to the taxane binding pocket and by directly stabilising the microtubule lattice by increasing structured water molecules and delayed GTP hydrolysis.
May 8, 2026 at 2:23 PM
Jingyi Luo (Ti lab) identifies a single amino acid change in beta3-tubulin that can sensitise cancer cells to paclitaxel by allosteric changes to the taxane binding pocket and by directly stabilising the microtubule lattice by increasing structured water molecules and delayed GTP hydrolysis.
Change of machine: Andrew McMahon describes the elangosome that builds the bacterial cell wall. He is using Minflux to track individual rodA synthase molecules.
May 8, 2026 at 2:05 PM
Change of machine: Andrew McMahon describes the elangosome that builds the bacterial cell wall. He is using Minflux to track individual rodA synthase molecules.
Flash talk session 2 with @eva-kreysing-lab.bsky.social talking about how neuronal maturation on stiff and soft substrates is regulated via piezo1 and TTR. Amy Godfrey introduces accessible microfluidics that is simple, cheap, fast and reliable and uses it to bend microtubules...
May 8, 2026 at 1:45 PM
Flash talk session 2 with @eva-kreysing-lab.bsky.social talking about how neuronal maturation on stiff and soft substrates is regulated via piezo1 and TTR. Amy Godfrey introduces accessible microfluidics that is simple, cheap, fast and reliable and uses it to bend microtubules...
Now some theory of beating cilia from Benjamin Friedrich @friedrich-group.bsky.social describing a stochastic dynamic sliding control model.
May 8, 2026 at 1:05 PM
Now some theory of beating cilia from Benjamin Friedrich @friedrich-group.bsky.social describing a stochastic dynamic sliding control model.
Alice Brinkworth continues the flagellum theme with cryo electron tomography of microgamete cells from Plasmodium revealing non-canonical microtubule arrangements
May 8, 2026 at 12:45 PM
Alice Brinkworth continues the flagellum theme with cryo electron tomography of microgamete cells from Plasmodium revealing non-canonical microtubule arrangements