Sebastian Shaw
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millseba.bsky.social
Sebastian Shaw
@millseba.bsky.social
Dad. Scientist. Interested in how Cryptosoridium tricks its host cells!
Pinned
Exciting news!!
I’ve been awarded an #SNSFStartingGrant and will join the Institute of Parasitology, University of Zurich as an Assistant Professor in summer 2026.
A dream come true! 🥺
Reposted by Sebastian Shaw
Registration & abstract submission are open for the 37th Molecular Parasitology Meeting (MPM XXXVII) 🧫
@MJGubbels @Deepali_Ravel @omartheharb
Sept 13–17, 2026 | Woods Hole, MA + virtual
Abstract deadline: June 19
@rmc9z.bsky.social @mjgubbels.bsky.social @omarharb.org
parasitesrule.com/mpm-xxxvii
May 28, 2026 at 1:24 PM
Reposted by Sebastian Shaw
Out Now! Genomic heterogeneity of NAD(P)H dehydrogenase predisposes Cryptosporidium to clofazimine resistance #MicroSky
Genomic heterogeneity of NAD(P)H dehydrogenase predisposes Cryptosporidium to clofazimine resistance
Nature Microbiology, Published online: 13 May 2026; doi:10.1038/s41564-026-02331-5Forward and reverse genetics identifies the mode of action of clofazimine in the parasite Cryptosporidium. The genomic locus encoding the target is heterogeneous, and a resistance-conferring allele is already widely distributed.
go.nature.com
May 14, 2026 at 9:38 AM
Excited to share our new paper, co-led by Gracyn Buenconsejo and me.

Why did a promising anti-#Cryptosporidium drug fail?

We asked whether the parasite itself might already be genetically prepared to escape treatment.
doi.org/10.1038/s415...
#Clofazimine #forwardgenetics
Genomic heterogeneity of NAD(P)H dehydrogenase predisposes Cryptosporidium to clofazimine resistance - Nature Microbiology
Forward and reverse genetics identifies the mode of action of clofazimine in the parasite Cryptosporidium. The genomic locus encoding the target is heterogeneous, and a resistance-conferring allele is...
doi.org
May 13, 2026 at 11:33 AM
3rd edition of the cheese bracket, and we have an winner: Cabriolait from Belgium! 🧀

On its way to 1st place, it defeated one Italian, two US, and one Swiss cheese. An impressive run!
May 9, 2026 at 10:29 AM
Reposted by Sebastian Shaw
Science is good. We should fund it.
April 11, 2026 at 12:14 AM
Super excited about this!
🧑‍🔬 The program for the scientific session of the ParaFrap Next Generation in Parasitology Workshop is now available!

🎟️ A few places are still available to attend the session in Montpellier. Registration is free but mandatory.

👉 forms.gle/q1ZZJbqu87CD...
April 9, 2026 at 10:31 PM
Did a little experiment with Hannah and her friend from school: they collected some cheek cells from saliva and looked at them under the microscope.

Their excitement when the cells came into view was priceless. A nice reminder that even simple experiments can sparkcuriosity. 🔬
March 29, 2026 at 5:06 AM
This week’s family theme 👇🏻👇🏻👇🏻
March 11, 2026 at 9:50 PM
Reposted by Sebastian Shaw
PhD opportunity at LMU Munich 🇩🇪
Join our lab to study the molecular and cellular biology of Apicomplexan parasites, with a focus on the apical complex, motility regulation, and post-translational modifications.
Apply: [email protected]
job-portal.lmu.de/jobposting/6...
PhD student (m/w/d)
job-portal.lmu.de
March 10, 2026 at 4:03 PM
Reposted by Sebastian Shaw
📆 Join us for the scientific session of the ParaFrap Next Generation in Parasitology Workshop (May 18-21, 2026, Montpellier) !

🧑‍🔬 Junior PIs will present their work. Registration is free but mandatory (includes lunch & coffee breaks).

Spots are limited, register now!
👉 forms.gle/bYsb47iZG7pR...
March 9, 2026 at 9:23 AM
Reposted by Sebastian Shaw
When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.
March 3, 2026 at 12:10 PM
🚨 Postdoc position 🚨
I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026).
Details & application:
jobs.uzh.ch/job-vacancie....

Please share! 😊
UZH: Postdoc
The newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl...
jobs.uzh.ch
February 19, 2026 at 2:00 PM
There are few emails better than one that says:
“Happy to in principle accept your study for publication.” 🎉
February 16, 2026 at 7:52 PM
Happy International Day of Women and Girls in Science! Let’s continue to support and celebrate them, and fight for equal opportunities for women in STEM! Shout-out to @shubhabevkal.bsky.social and @fra-florini.bsky.social! You’re the best!
#WomenInScience #WomenInSTEM
February 11, 2026 at 8:13 PM
Joyful snow day!
January 25, 2026 at 5:15 PM
Reposted by Sebastian Shaw
🦠 Grad students & postdocs in parasitology:
Apply now for the Biology of Parasitism (BoP): Modern Approaches course at @MBLScience.
Hands-on labs, expert lectures, and cutting-edge tools.
📅 Summer 2026 | ⏰ Deadline Feb 5
🔗 mbl.edu/courses
December 16, 2025 at 6:53 PM
Reposted by Sebastian Shaw
New paper out !
Want to learn more about fascinating proteasome biology and Artemisinin resistance in Malaria parasites ? Check out our preprint:

www.biorxiv.org/content/10.1...
Stage-specific regulation of the Plasmodium falciparum proteasome activity reveals adaptive rewiring in artemisinin resistance
The ubiquitin-proteasome system (UPS) is essential for Plasmodium falciparum to maintain protein homeostasis, adapt to proteotoxic stress, and regulate parasite growth and stage transitions. The prote...
www.biorxiv.org
November 26, 2025 at 11:21 PM
Reposted by Sebastian Shaw
Publication alert! 🔔 Our recent work exploring how Plasmodium uses a Rad51 independent homologous recombination to diversify its var gene repertoire is now published in 🧬 Nucleic Acids Research! @oupprimary.bsky.social @narjournal.bsky.social Read more here.
tinyurl.com/794brb6h
Validate User
tinyurl.com
November 26, 2025 at 4:16 PM
Repost for World #AMR Awareness Week.
#AntimicrobialResistance

➡️ www.biorxiv.org/content/10.1...
www.biorxiv.org
November 21, 2025 at 10:45 AM
Exciting news!!
I’ve been awarded an #SNSFStartingGrant and will join the Institute of Parasitology, University of Zurich as an Assistant Professor in summer 2026.
A dream come true! 🥺
October 31, 2025 at 2:39 PM
Reposted by Sebastian Shaw
✨ Searching for extraterrestrial life or combating speech disorders: The SNSF is awarding #SNSFStartingGrants to 41 outstanding researchers. They will receive a maximum of CHF 1 million to lead a project with their own #research team at a Swiss university. 🚀

ℹ️ sohub.io/aq26
October 31, 2025 at 9:30 AM
Reposted by Sebastian Shaw
Save the date, next Cryptosporidium meeting in Edinburgh May 24-26, 2026. Register for email updates via the QR code below.
October 13, 2025 at 11:42 AM
As an immigrant scientist in the U.S., travel bans and visa uncertainty are taking a toll | Science | AAAS www.science.org/content/arti...
As an immigrant scientist in the U.S., travel bans and visa uncertainty are taking a toll
“I began to question whether I truly belonged,” this postdoc writes
www.science.org
October 21, 2025 at 4:36 AM
Reposted by Sebastian Shaw
The parasitesrule site has an archive of abstract books from the Molecular Parasitology Meeting (MPM) & the Kinetoplastid Molecular Cell Biology Meeting (KMCB). The book from the first MPM (1990) is also there!
🔗 parasitesrule.com/archive
October 15, 2025 at 1:41 PM
Our latest story on Clofazimine resistance in Cryptosporidium! What started as a side project turned into one of the most interesting stories.

Genetics 101 😊

#Cryptosporidium #Apicomplexa #Clofazimine #AntimicrobialResistance #AMR #ParasiteResearch

www.biorxiv.org/content/10.1...
Widespread genomic heterogeneity at the type II NAD(P)H dehydrogenase locus predisposes Cryptosporidium to clofazimine resistance
The parasite Cryptosporidium is a leading cause of life-threatening diarrheal disease, and effective treatment is not available. The discovery of potent anti-Cryptosporidium activity of clofazimine, o...
www.biorxiv.org
October 8, 2025 at 11:25 AM