Martial Marbouty
@mmarbout.bsky.social
Organizations, structures and dynamics of microbial communities. Phages lover. CNRS researcher. Developer of HiC technics and bioinformatic pipelines applied to metagenomes. Opinions are my own.
🚨 ‼️ NEW PUBLICATION ‼️
While we start to know a lot about how bacterial genomes are organized in 3D, almost nothing is known about phage genome once it enters a bacterial cell.
read the paper here:
www.science.org/doi/10.1126/...
While we start to know a lot about how bacterial genomes are organized in 3D, almost nothing is known about phage genome once it enters a bacterial cell.
read the paper here:
www.science.org/doi/10.1126/...
Bacteriophage PAK_P3 genome structuration and dynamics during infection of Pseudomonas aeruginosa reveal specific interaction patterns
While the dynamic changes in genome organization in cellular organisms have been well described, the three-dimensional (3D) folding of phage genomes during the infection of their host is extremely lim...
www.science.org
August 30, 2026 at 9:08 AM
🚨 ‼️ NEW PUBLICATION ‼️
While we start to know a lot about how bacterial genomes are organized in 3D, almost nothing is known about phage genome once it enters a bacterial cell.
read the paper here:
www.science.org/doi/10.1126/...
While we start to know a lot about how bacterial genomes are organized in 3D, almost nothing is known about phage genome once it enters a bacterial cell.
read the paper here:
www.science.org/doi/10.1126/...
Reposted by Martial Marbouty
This one means a lot. Our paper, “Large extrachromosomal replicons are widespread across bacterial lineages and show coordinated replication termination and spatial coupling with the chromosome,” is out!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Large extrachromosomal replicons are widespread across bacterial lineages and show coordinated replication termination and spatial coupling with the chromosome - Nature Communications
Bacterial genomes often include extrachromosomal replicons, ranging from small plasmids to chromosome-scale replicons. Here, Czarnecki et al. analyse more than 40,000 complete bacterial genomes and sh...
doi.org
May 4, 2026 at 12:34 PM
This one means a lot. Our paper, “Large extrachromosomal replicons are widespread across bacterial lineages and show coordinated replication termination and spatial coupling with the chromosome,” is out!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
💥 alert article 💥
New preprint from the lab !!! 🥳
In this work, we explore the 3D genome architecture of the virulent phage PAK_P3 during its infection cycle in P. Aeruginosa. We unveil a highly dynamic structuration as well as specific interactions patterns.
www.biorxiv.org/content/bior...
New preprint from the lab !!! 🥳
In this work, we explore the 3D genome architecture of the virulent phage PAK_P3 during its infection cycle in P. Aeruginosa. We unveil a highly dynamic structuration as well as specific interactions patterns.
www.biorxiv.org/content/bior...
www.biorxiv.org
December 17, 2025 at 7:14 AM
💥 alert article 💥
New preprint from the lab !!! 🥳
In this work, we explore the 3D genome architecture of the virulent phage PAK_P3 during its infection cycle in P. Aeruginosa. We unveil a highly dynamic structuration as well as specific interactions patterns.
www.biorxiv.org/content/bior...
New preprint from the lab !!! 🥳
In this work, we explore the 3D genome architecture of the virulent phage PAK_P3 during its infection cycle in P. Aeruginosa. We unveil a highly dynamic structuration as well as specific interactions patterns.
www.biorxiv.org/content/bior...
Reposted by Martial Marbouty
#ResultatScientifique 🔎| Et si les phages, ces virus des bactéries, pouvaient infecter plusieurs espèces à la fois et remodeler l’écologie microbienne ? 🦠
✍️ Martial Marbouty
📕 @natmicrobiol.nature.com | buff.ly/1R9kqjv
✍️ Martial Marbouty
📕 @natmicrobiol.nature.com | buff.ly/1R9kqjv
Les phages à large spectre, omniprésents dans les écosystèmes
Les phages, les virus des bactéries, représentent les entités génétiques les plus abondantes de notre environnement.
www.insb.cnrs.fr
October 7, 2025 at 9:53 AM
#ResultatScientifique 🔎| Et si les phages, ces virus des bactéries, pouvaient infecter plusieurs espèces à la fois et remodeler l’écologie microbienne ? 🦠
✍️ Martial Marbouty
📕 @natmicrobiol.nature.com | buff.ly/1R9kqjv
✍️ Martial Marbouty
📕 @natmicrobiol.nature.com | buff.ly/1R9kqjv
Reposted by Martial Marbouty
New paper!
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC
You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
Phages with a broad host range are common across ecosystems - Nature Microbiology
Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.
www.nature.com
September 19, 2025 at 12:49 PM
New paper!
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC
You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
Phages with a broad host range are common across ecosystems - Nature Microbiology
Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.
www.nature.com
September 19, 2025 at 9:32 AM
You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
Reposted by Martial Marbouty
Reportage de @celineloozen.bsky.social > Itw de Martial Marbouty, chercheur CNRS au laboratoire Régulation Spatiale des Génomes de l'Institut Pasteur sur l’étude des interactions phages-bactéries tinyurl.com/m9uxwjct #ScienceCQFD
Comment détourner les bactériophages à des fins thérapeutiques.
Dans nos organismes, les relations entre bactéries et phages tissent un réseau complexe dont l'analyse ouvre des thérapies innovantes, notamment pour réguler le microbiote intestinal.
tinyurl.com
May 21, 2025 at 2:34 PM
Reportage de @celineloozen.bsky.social > Itw de Martial Marbouty, chercheur CNRS au laboratoire Régulation Spatiale des Génomes de l'Institut Pasteur sur l’étude des interactions phages-bactéries tinyurl.com/m9uxwjct #ScienceCQFD
Reposted by Martial Marbouty
#Podcast du jour. Virus bactériophages : découverts début XXe s, ils ont été délaissés dans la lutte antibactérienne au profit des antibiotiques. Face à l’antibiorésistance, les bactériophages pourraient-ils faire leur grand retour ? tinyurl.com/yoat4jcu avec Anne Chevallereau et Jérôme Gabard
Bactériophages, une épopée thérapeutique
Découverts au début du 20e siècle, les virus bactériophages ont été rapidement délaissés dans la lutte antibactérienne au profit des antibiotiques. Mais face à la crise de l’antibiorésistance, ces "ma...
tinyurl.com
May 21, 2025 at 3:06 PM
#Podcast du jour. Virus bactériophages : découverts début XXe s, ils ont été délaissés dans la lutte antibactérienne au profit des antibiotiques. Face à l’antibiorésistance, les bactériophages pourraient-ils faire leur grand retour ? tinyurl.com/yoat4jcu avec Anne Chevallereau et Jérôme Gabard