Fabrice Caudron
@mnemon.bsky.social
Cell biologist, yeast geneticist @IGMM Montpellier, CNRS. Prion-like proteins, asymmetric cell division, RNA-binding proteins, condensates, aging.
Reposted by Fabrice Caudron
Postdoctoral position available! Help us to understand how fungi cause disease, by bringing data-driven engineering biology and cool fluorescent protein tools into fungal pathogens.
Details: ewallace.github.io/news/postdoc...
Please share!
Details: ewallace.github.io/news/postdoc...
Please share!
Postdoctoral position in fungal engineering biology
ewallace.github.io
August 19, 2026 at 1:15 PM
Postdoctoral position available! Help us to understand how fungi cause disease, by bringing data-driven engineering biology and cool fluorescent protein tools into fungal pathogens.
Details: ewallace.github.io/news/postdoc...
Please share!
Details: ewallace.github.io/news/postdoc...
Please share!
Reposted by Fabrice Caudron
🚀 New preprint 🥳 Fantastic work by our recent PhD graduate Daan !
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
PAIP1 couples mRNA export to cytoplasmic mRNP remodeling and poly(A) homeostasis https://www.biorxiv.org/content/10.64898/2026.07.31.742013v1
August 3, 2026 at 2:45 PM
🚀 New preprint 🥳 Fantastic work by our recent PhD graduate Daan !
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
Reposted by Fabrice Caudron
New preprint! How does a cell "know" how big to make its nucleus? This has puzzled biologists since the 1800’s. We show the answer is physics: colloid osmotic pressure. 🧵1/5
Nuclear size and physical properties of the nucleoplasm are determined by colloid osmotic pressure at the nuclear envelope https://www.biorxiv.org/content/10.64898/2026.07.21.739918v1
July 27, 2026 at 5:52 PM
New preprint! How does a cell "know" how big to make its nucleus? This has puzzled biologists since the 1800’s. We show the answer is physics: colloid osmotic pressure. 🧵1/5
And it's a wrap up for LMO15, meeting of the french speaking yeast community. Really cool blend of topics in beautiful INRAE Montpellier. A big thank to the organisers! And congratulations to the best posters awards, including Coline Gibout (ExposUM PhD student) from the lab.
#ProudPI #Yeast
#ProudPI #Yeast
July 3, 2026 at 1:12 PM
Reposted by Fabrice Caudron
"Un dirigeant politique incapable d’assimiler un rapport du GIEC avec ces aides est tout simplement incapable d’assurer la fonction à laquelle il prétend..." www.
lemonde.fr/sciences-au-carre/article/2026/06/30/mesinformation-climatique-qui-est-responsable_6717254_6565027.html
lemonde.fr/sciences-au-carre/article/2026/06/30/mesinformation-climatique-qui-est-responsable_6717254_6565027.html
Mésinformation climatique, qui est responsable ?
Lorsque sur un plateau TV un climatologue entend un journaliste dire que les scientifiques « n’ont pas été assez clairs » sur le changement climatique, il a le droit de s’énerver. Mais alors, qui accu...
lemonde.fr
June 30, 2026 at 4:22 PM
"Un dirigeant politique incapable d’assimiler un rapport du GIEC avec ces aides est tout simplement incapable d’assurer la fonction à laquelle il prétend..." www.
lemonde.fr/sciences-au-carre/article/2026/06/30/mesinformation-climatique-qui-est-responsable_6717254_6565027.html
lemonde.fr/sciences-au-carre/article/2026/06/30/mesinformation-climatique-qui-est-responsable_6717254_6565027.html
Reposted by Fabrice Caudron
I have been thinking since yesterday about why I find the 1% thing so, so disturbing. It's a visceral reaction of 'just no', which goes beyond the general yuck towards the enshittification of/via AI. I have finally put my finger on it: it is the feeling you get when
June 26, 2026 at 4:21 PM
I have been thinking since yesterday about why I find the 1% thing so, so disturbing. It's a visceral reaction of 'just no', which goes beyond the general yuck towards the enshittification of/via AI. I have finally put my finger on it: it is the feeling you get when
Reposted by Fabrice Caudron
Whether condensates have real biological functions has long been debated. Our new Molecular Cell Perspective argues translation is a core one, not just repression. Next: live high-res imaging + probing condensate dynamics should let us get at where translation starts and how condensates shape it.
June 24, 2026 at 8:32 AM
Whether condensates have real biological functions has long been debated. Our new Molecular Cell Perspective argues translation is a core one, not just repression. Next: live high-res imaging + probing condensate dynamics should let us get at where translation starts and how condensates shape it.
Reposted by Fabrice Caudron
Dynamics of phosphofructokinase condensation are regulated by metabolic and redox cues https://www.biorxiv.org/content/10.64898/2026.06.09.731068v1
June 10, 2026 at 10:34 AM
Dynamics of phosphofructokinase condensation are regulated by metabolic and redox cues https://www.biorxiv.org/content/10.64898/2026.06.09.731068v1
Reposted by Fabrice Caudron
Paying peer reviewers works.
Expanded Fast & Fair experiment @biologyopen.bsky.social:
• 5.5 vs 37.7 working days to decision with reviews
• ~3 vs ~9 reviewer invitations per manuscript
• no reduction in editor-assessed review quality
• similar acceptance rates
www.biorxiv.org/content/10.6...
Expanded Fast & Fair experiment @biologyopen.bsky.social:
• 5.5 vs 37.7 working days to decision with reviews
• ~3 vs ~9 reviewer invitations per manuscript
• no reduction in editor-assessed review quality
• similar acceptance rates
www.biorxiv.org/content/10.6...
June 3, 2026 at 12:05 PM
Paying peer reviewers works.
Expanded Fast & Fair experiment @biologyopen.bsky.social:
• 5.5 vs 37.7 working days to decision with reviews
• ~3 vs ~9 reviewer invitations per manuscript
• no reduction in editor-assessed review quality
• similar acceptance rates
www.biorxiv.org/content/10.6...
Expanded Fast & Fair experiment @biologyopen.bsky.social:
• 5.5 vs 37.7 working days to decision with reviews
• ~3 vs ~9 reviewer invitations per manuscript
• no reduction in editor-assessed review quality
• similar acceptance rates
www.biorxiv.org/content/10.6...
Reposted by Fabrice Caudron
Save the date : Seminar by Edward Wallace from the University of Edinburgh on Tuesday 12th May at 11h @ewjwallace.bsky.social @edinburgh-uni.bsky.social
May 5, 2026 at 12:17 PM
Save the date : Seminar by Edward Wallace from the University of Edinburgh on Tuesday 12th May at 11h @ewjwallace.bsky.social @edinburgh-uni.bsky.social
Reposted by Fabrice Caudron
Reposted by Fabrice Caudron
Doing the periodic cleaning of used plasmid miniprep columns and realized in honor of Earth Day it may be worth reminding you molecular biologists:
Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic
Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic
April 22, 2026 at 9:34 PM
Doing the periodic cleaning of used plasmid miniprep columns and realized in honor of Earth Day it may be worth reminding you molecular biologists:
Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic
Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic
Reposted by Fabrice Caudron
🔬IGMM (CNRS/ Univ Montpellier) is hiring Group Leaders in Innovative Biology. @cnrsbiologie.bsky.social @cnrs.fr @umontpellier.bsky.social
📅 1 May–15 June 2026
📩 [email protected]
📎Full information 👇
#LifeScience #MolecularBiology #Research #PI #CNRS
📅 1 May–15 June 2026
📩 [email protected]
📎Full information 👇
#LifeScience #MolecularBiology #Research #PI #CNRS
April 17, 2026 at 7:22 AM
🔬IGMM (CNRS/ Univ Montpellier) is hiring Group Leaders in Innovative Biology. @cnrsbiologie.bsky.social @cnrs.fr @umontpellier.bsky.social
📅 1 May–15 June 2026
📩 [email protected]
📎Full information 👇
#LifeScience #MolecularBiology #Research #PI #CNRS
📅 1 May–15 June 2026
📩 [email protected]
📎Full information 👇
#LifeScience #MolecularBiology #Research #PI #CNRS
Reposted by Fabrice Caudron
🌟 Postdoc position open at Karolinska Institutet to advance research on healthy aging 🔬 🧫
See here: : lengefeldlab.com
Please RT! We are excited for your application 😄
@ki.se
@novo-nordisk.bsky.social
See here: : lengefeldlab.com
Please RT! We are excited for your application 😄
@ki.se
@novo-nordisk.bsky.social
April 15, 2026 at 5:49 AM
🌟 Postdoc position open at Karolinska Institutet to advance research on healthy aging 🔬 🧫
See here: : lengefeldlab.com
Please RT! We are excited for your application 😄
@ki.se
@novo-nordisk.bsky.social
See here: : lengefeldlab.com
Please RT! We are excited for your application 😄
@ki.se
@novo-nordisk.bsky.social
Reposted by Fabrice Caudron
Sequence and structure of protein binding sites in RNA impact biomolecular condensates https://www.biorxiv.org/content/10.64898/2026.02.24.707737v1
February 26, 2026 at 2:30 AM
Sequence and structure of protein binding sites in RNA impact biomolecular condensates https://www.biorxiv.org/content/10.64898/2026.02.24.707737v1
Reposted by Fabrice Caudron
You are finishing your PhD and looking to continue in science?
The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....
Thanks for reposting!
The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....
Thanks for reposting!
Contact/Job - Department of Molecular and Cellular Biology - UNIGE
mocel.unige.ch
March 3, 2026 at 9:42 AM
You are finishing your PhD and looking to continue in science?
The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....
Thanks for reposting!
The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....
Thanks for reposting!
Reposted by Fabrice Caudron
We are hiring!
January 30, 2026 at 4:33 PM
We are hiring!
Reposted by Fabrice Caudron
I just published: ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re…
medium.com
December 3, 2025 at 11:42 AM
I just published: ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.
medium.com/p/erc-plus-j...
Reposted by Fabrice Caudron
🚀 Nouvelle publication !
L’éditorial de Jamal Tazi sur le mécanisme d’action de l’obefazimod est en ligne dans Drug Discovery Today.
🔗 doi.org/10.1016/j.dr...
Une synthèse issue de plus de 10 ans de recherche liant ARN, inflammation et innovation thérapeutique.
www.sciencedirect.com/science/arti...
L’éditorial de Jamal Tazi sur le mécanisme d’action de l’obefazimod est en ligne dans Drug Discovery Today.
🔗 doi.org/10.1016/j.dr...
Une synthèse issue de plus de 10 ans de recherche liant ARN, inflammation et innovation thérapeutique.
www.sciencedirect.com/science/arti...
Redirecting
doi.org
November 21, 2025 at 8:01 AM
🚀 Nouvelle publication !
L’éditorial de Jamal Tazi sur le mécanisme d’action de l’obefazimod est en ligne dans Drug Discovery Today.
🔗 doi.org/10.1016/j.dr...
Une synthèse issue de plus de 10 ans de recherche liant ARN, inflammation et innovation thérapeutique.
www.sciencedirect.com/science/arti...
L’éditorial de Jamal Tazi sur le mécanisme d’action de l’obefazimod est en ligne dans Drug Discovery Today.
🔗 doi.org/10.1016/j.dr...
Une synthèse issue de plus de 10 ans de recherche liant ARN, inflammation et innovation thérapeutique.
www.sciencedirect.com/science/arti...
Reposted by Fabrice Caudron
L’Université de Montpellier publie un article sur le développement du médicament obefazimod, fruit de 20 ans de recherche et d’un partenariat public-privé avec l’IGMM et le CNRS.
@cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
www.umontpellier.fr/articles/des...
@cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
www.umontpellier.fr/articles/des...
Des labos de l’UM à Abivax : le fabuleux destin du médicament qui voulait mater les maladies chroniques de l’intestin - Université de Montpellier
Fruit d’une vingtaine d’années de recherches, l’obefazimod pourrait faire son entrée sur le marché pharmaceutique d’ici deux ans. Imaginé par un chercheur à l'Université de Montpellier et développé pa...
www.umontpellier.fr
October 30, 2025 at 12:35 PM
L’Université de Montpellier publie un article sur le développement du médicament obefazimod, fruit de 20 ans de recherche et d’un partenariat public-privé avec l’IGMM et le CNRS.
@cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
www.umontpellier.fr/articles/des...
@cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social
www.umontpellier.fr/articles/des...
Reposted by Fabrice Caudron
Investigating protein aggregation in mitotic spindle function during aging
Stage Master 2 #BIOLuMStage
@crbm-montpellier.bsky.social
@igmm-montpel.bsky.social
Stage Master 2 #BIOLuMStage
@crbm-montpellier.bsky.social
@igmm-montpel.bsky.social
October 14, 2025 at 1:33 PM
Investigating protein aggregation in mitotic spindle function during aging
Stage Master 2 #BIOLuMStage
@crbm-montpellier.bsky.social
@igmm-montpel.bsky.social
Stage Master 2 #BIOLuMStage
@crbm-montpellier.bsky.social
@igmm-montpel.bsky.social
Reposted by Fabrice Caudron
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍.
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
Boa Constrictor Brain Cells Slither into Focus
From reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton.
www.the-scientist.com
October 13, 2025 at 11:13 AM
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍.
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
Reposted by Fabrice Caudron
#ResultatScientifique 🔎| Faire taire les gènes est aussi crucial que les activer : le répresseur Snail révèle son rôle essentiel dans le développement embryonnaire 🧬
✍️ @laghalab.bsky.social et Ovidiu Radulescu
📕 @natcomms.nature.com | buff.ly/pmtzA1t
✍️ @laghalab.bsky.social et Ovidiu Radulescu
📕 @natcomms.nature.com | buff.ly/pmtzA1t
L’art délicat de faire taire les gènes
Le développement embryonnaire ne requiert pas uniquement l’activation des gènes, mais également une régulation fine de leur répression.
buff.ly
September 29, 2025 at 2:01 PM
#ResultatScientifique 🔎| Faire taire les gènes est aussi crucial que les activer : le répresseur Snail révèle son rôle essentiel dans le développement embryonnaire 🧬
✍️ @laghalab.bsky.social et Ovidiu Radulescu
📕 @natcomms.nature.com | buff.ly/pmtzA1t
✍️ @laghalab.bsky.social et Ovidiu Radulescu
📕 @natcomms.nature.com | buff.ly/pmtzA1t
Reposted by Fabrice Caudron
And if you're interested in the associated paper, now out in @genetics-gsa.bsky.social G3: academic.oup.com/g3journal/ad...
August 20, 2025 at 12:53 PM
And if you're interested in the associated paper, now out in @genetics-gsa.bsky.social G3: academic.oup.com/g3journal/ad...