Nature Genetics
@natgenet.nature.com
Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. Part of @natureportfolio.bsky.social
Repost/like=interesting/relevant, not necessarily endorsement.
Repost/like=interesting/relevant, not necessarily endorsement.
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📢 @natgenet.nature.com September issue's out!
Featuring:
✅myeloid cells in AD
✅multiple sclerosis multiancestry GWAS & multiomics
✅functional AI-designed enhancers in mice
✅hPTMs cross species profiling with iChIP2
✅data integration with SCIGMA
and much more!
⬇️
www.nature.com/ng/volumes/5...
Featuring:
✅myeloid cells in AD
✅multiple sclerosis multiancestry GWAS & multiomics
✅functional AI-designed enhancers in mice
✅hPTMs cross species profiling with iChIP2
✅data integration with SCIGMA
and much more!
⬇️
www.nature.com/ng/volumes/5...
📢📢📢
@natgenet.nature.com editor Chiara Anania will be joining the 5th #Epigenetics Conference @fusionconf.bsky.social
📍Lisbon, Portugal 📅1-4 Oct 26
Please feel free to reach out to her if you want to discuss your research!
fusion-conferences.com/conference/206
@natgenet.nature.com editor Chiara Anania will be joining the 5th #Epigenetics Conference @fusionconf.bsky.social
📍Lisbon, Portugal 📅1-4 Oct 26
Please feel free to reach out to her if you want to discuss your research!
fusion-conferences.com/conference/206
5th Epigenetics Conference | Fusion Conferences
Highlighting how chromatin organisation, nuclear architecture, gene regulatory networks, metabolism and RNA-based mechanisms converge to shape cell identity and plasticity across development, homeosta...
fusion-conferences.com
September 30, 2026 at 8:14 AM
📢📢📢
@natgenet.nature.com editor Chiara Anania will be joining the 5th #Epigenetics Conference @fusionconf.bsky.social
📍Lisbon, Portugal 📅1-4 Oct 26
Please feel free to reach out to her if you want to discuss your research!
fusion-conferences.com/conference/206
@natgenet.nature.com editor Chiara Anania will be joining the 5th #Epigenetics Conference @fusionconf.bsky.social
📍Lisbon, Portugal 📅1-4 Oct 26
Please feel free to reach out to her if you want to discuss your research!
fusion-conferences.com/conference/206
📢PUBLISHED @natgenet.nature.com
📰CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates.
By Ting Hu, Lei Shi and colleagues.
⬇️
www.nature.com/articles/s41...
📰CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates.
By Ting Hu, Lei Shi and colleagues.
⬇️
www.nature.com/articles/s41...
CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates - Nature Genetics
The authors use tree shrews in multispecies comparisons to identify evolutionary changes in CCNB1IP1 expression associated with primate cortical expansion and folding, and investigate the cis-regulato...
www.nature.com
September 30, 2026 at 7:54 AM
📢PUBLISHED @natgenet.nature.com
📰CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates.
By Ting Hu, Lei Shi and colleagues.
⬇️
www.nature.com/articles/s41...
📰CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates.
By Ting Hu, Lei Shi and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver disease.
By Eleni Papachristoforou, Prakash Ramachandran and colleagues.
⬇️
www.nature.com/articles/s41...
📰A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver disease.
By Eleni Papachristoforou, Prakash Ramachandran and colleagues.
⬇️
www.nature.com/articles/s41...
A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver disease - Nature Genetics
This study provides a single-cell RNA-sequencing atlas of 77 healthy and chronic liver disease livers and identifies a subpopulation of pro-inflammatory scar-associated macrophages enriched for OLR1 e...
www.nature.com
September 30, 2026 at 7:51 AM
📢PUBLISHED @natgenet.nature.com
📰A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver disease.
By Eleni Papachristoforou, Prakash Ramachandran and colleagues.
⬇️
www.nature.com/articles/s41...
📰A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver disease.
By Eleni Papachristoforou, Prakash Ramachandran and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment.
By Jeremy T. Baeten, Kelly L. Bolton and colleagues.
⬇️
www.nature.com/articles/s41...
📰Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment.
By Jeremy T. Baeten, Kelly L. Bolton and colleagues.
⬇️
www.nature.com/articles/s41...
Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment - Nature Genetics
The authors show that platinum is a greater driver of DNA damage response gene-mutant clonal hematopoiesis than poly(ADP-ribose) polymerase inhibitors and that the presence of germline mutations confe...
www.nature.com
September 30, 2026 at 7:48 AM
📢PUBLISHED @natgenet.nature.com
📰Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment.
By Jeremy T. Baeten, Kelly L. Bolton and colleagues.
⬇️
www.nature.com/articles/s41...
📰Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment.
By Jeremy T. Baeten, Kelly L. Bolton and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn’s disease.
By Yu Zhao, Sebastian Pott and colleagues.
⬇️
www.nature.com/articles/s41...
📰Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn’s disease.
By Yu Zhao, Sebastian Pott and colleagues.
⬇️
www.nature.com/articles/s41...
Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn’s disease - Nature Genetics
This study uses single-cell ATAC–seq to map chromatin accessibility in the intestinal mucosa from patients with Crohn’s disease and healthy controls to characterize regulatory programs associated with...
www.nature.com
September 30, 2026 at 7:47 AM
📢PUBLISHED @natgenet.nature.com
📰Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn’s disease.
By Yu Zhao, Sebastian Pott and colleagues.
⬇️
www.nature.com/articles/s41...
📰Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn’s disease.
By Yu Zhao, Sebastian Pott and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Genome-wide mapping of common and rare variant effects on adiposity across childhood.
By Katherine A. Kentistou, Stefan Johansson and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genome-wide mapping of common and rare variant effects on adiposity across childhood.
By Katherine A. Kentistou, Stefan Johansson and colleagues.
⬇️
www.nature.com/articles/s41...
Genome-wide mapping of common and rare variant effects on adiposity across childhood - Nature Genetics
Genome-wide analyses identify common and rare variants associated with childhood adiposity, including rare protein-coding variants in ADCY3, CALCR, MC4R, MRAP2, POMC and MYH13 that exhibit stronger ef...
www.nature.com
September 30, 2026 at 7:45 AM
📢PUBLISHED @natgenet.nature.com
📰Genome-wide mapping of common and rare variant effects on adiposity across childhood.
By Katherine A. Kentistou, Stefan Johansson and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genome-wide mapping of common and rare variant effects on adiposity across childhood.
By Katherine A. Kentistou, Stefan Johansson and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Euchromatin forms condensed domains with short active regions on the surface.
By Joseph M. Paggi, Lawrence Y. Long & Bin Zhang
⬇️
www.nature.com/articles/s41...
📰Euchromatin forms condensed domains with short active regions on the surface.
By Joseph M. Paggi, Lawrence Y. Long & Bin Zhang
⬇️
www.nature.com/articles/s41...
Euchromatin forms condensed domains with short active regions on the surface - Nature Genetics
Simulations integrating micro-C and imaging data provide a coherent view of chromatin organization from nucleosomes to clutches to domains, revealing that most regions form compact domains but short r...
www.nature.com
September 30, 2026 at 7:43 AM
📢PUBLISHED @natgenet.nature.com
📰Euchromatin forms condensed domains with short active regions on the surface.
By Joseph M. Paggi, Lawrence Y. Long & Bin Zhang
⬇️
www.nature.com/articles/s41...
📰Euchromatin forms condensed domains with short active regions on the surface.
By Joseph M. Paggi, Lawrence Y. Long & Bin Zhang
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Atlas of cell types and regulatory elements underlying human facial diversity.
By Alek G. Erickson, @adameykolab.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
📰Atlas of cell types and regulatory elements underlying human facial diversity.
By Alek G. Erickson, @adameykolab.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
Atlas of cell types and regulatory elements underlying human facial diversity - Nature Genetics
Single-cell transcriptomics, spatial transcriptomics and chromatin accessibility maps of the human craniofacial region in developing embryos provide insights into the mechanisms underlying facial vari...
www.nature.com
September 30, 2026 at 7:40 AM
📢PUBLISHED @natgenet.nature.com
📰Atlas of cell types and regulatory elements underlying human facial diversity.
By Alek G. Erickson, @adameykolab.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
📰Atlas of cell types and regulatory elements underlying human facial diversity.
By Alek G. Erickson, @adameykolab.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency.
By Ran Tao, Paul A. Northcott and colleagues.
⬇️
www.nature.com/articles/s41...
📰Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency.
By Ran Tao, Paul A. Northcott and colleagues.
⬇️
www.nature.com/articles/s41...
Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency - Nature Genetics
Epigenomic analyses of medulloblastoma identify a bivalent/poised enhancer (EnhBiv) chromatin signature enriched for KDM2B binding in Group 3 and Group 4 tumors. Functional work suggests a selective d...
www.nature.com
September 30, 2026 at 7:39 AM
📢PUBLISHED @natgenet.nature.com
📰Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency.
By Ran Tao, Paul A. Northcott and colleagues.
⬇️
www.nature.com/articles/s41...
📰Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency.
By Ran Tao, Paul A. Northcott and colleagues.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Balancing phenotyping depth and representativeness in psychiatric genomics.
A Comment by Woojae Myung, Jisun Ryu & Hong-Hee Won.
⬇️
www.nature.com/articles/s41...
📰Balancing phenotyping depth and representativeness in psychiatric genomics.
A Comment by Woojae Myung, Jisun Ryu & Hong-Hee Won.
⬇️
www.nature.com/articles/s41...
Balancing phenotyping depth and representativeness in psychiatric genomics - Nature Genetics
Deep phenotyping can improve diagnostic precision in psychiatric genomics, but it remains susceptible to non-random, partly heritable selection bias that compromises representativeness. Accordingly, a...
www.nature.com
September 23, 2026 at 8:37 PM
📢OUT TODAY @natgenet.nature.com
📰Balancing phenotyping depth and representativeness in psychiatric genomics.
A Comment by Woojae Myung, Jisun Ryu & Hong-Hee Won.
⬇️
www.nature.com/articles/s41...
📰Balancing phenotyping depth and representativeness in psychiatric genomics.
A Comment by Woojae Myung, Jisun Ryu & Hong-Hee Won.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Genetic factor analysis for characterizing phenome-wide patterns of genetic pleiotropy.
By Jean Morrison, Matthew Stephens and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genetic factor analysis for characterizing phenome-wide patterns of genetic pleiotropy.
By Jean Morrison, Matthew Stephens and colleagues.
⬇️
www.nature.com/articles/s41...
Genetic factor analysis for characterizing phenome-wide patterns of genetic pleiotropy - Nature Genetics
Genetic factor analysis uses genome-wide association summary statistics to identify shared polygenic factors underlying patterns of cross-trait genetic associations, while automatically determining th...
www.nature.com
September 23, 2026 at 8:36 PM
📢OUT TODAY @natgenet.nature.com
📰Genetic factor analysis for characterizing phenome-wide patterns of genetic pleiotropy.
By Jean Morrison, Matthew Stephens and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genetic factor analysis for characterizing phenome-wide patterns of genetic pleiotropy.
By Jean Morrison, Matthew Stephens and colleagues.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat.
By Dhondup Lhamo, Steven S. Xu and colleagues.
⬇️
www.nature.com/articles/s41...
📰Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat.
By Dhondup Lhamo, Steven S. Xu and colleagues.
⬇️
www.nature.com/articles/s41...
Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat - Nature Genetics
Gb3 encodes an intracellular kinase–pseudokinase protein with a unique MAP3K-like domain that confers resistance to multiple greenbug biotypes in wheat.
www.nature.com
September 23, 2026 at 8:34 PM
📢OUT TODAY @natgenet.nature.com
📰Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat.
By Dhondup Lhamo, Steven S. Xu and colleagues.
⬇️
www.nature.com/articles/s41...
📰Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat.
By Dhondup Lhamo, Steven S. Xu and colleagues.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Single-nucleus atlas of cell-type specific genetic regulation in the human brain.
By Biao Zeng, Panos Roussos and colleagues.
⬇️
www.nature.com/articles/s41...
📰Single-nucleus atlas of cell-type specific genetic regulation in the human brain.
By Biao Zeng, Panos Roussos and colleagues.
⬇️
www.nature.com/articles/s41...
Single-nucleus atlas of cell-type specific genetic regulation in the human brain - Nature Genetics
Multi-resolution genetic regulatory atlas of the human brain from single-nucleus transcriptomics of 1,384 donors of diverse ancestries reveals cell type-specific regulation underlying genetic risk of ...
www.nature.com
September 23, 2026 at 8:32 PM
📢OUT TODAY @natgenet.nature.com
📰Single-nucleus atlas of cell-type specific genetic regulation in the human brain.
By Biao Zeng, Panos Roussos and colleagues.
⬇️
www.nature.com/articles/s41...
📰Single-nucleus atlas of cell-type specific genetic regulation in the human brain.
By Biao Zeng, Panos Roussos and colleagues.
⬇️
www.nature.com/articles/s41...
Reposted by Nature Genetics
🧬 Our “Behind the Paper” is now online at Nature Communities:
“Active chromatin is not simply open—it forms compact domains that cohesin keeps from mixing.”
📖 A short story behind our recent @natgenet.nature.com paper.
communities.springernature.com/posts/active...
www.nature.com/articles/s41...
“Active chromatin is not simply open—it forms compact domains that cohesin keeps from mixing.”
📖 A short story behind our recent @natgenet.nature.com paper.
communities.springernature.com/posts/active...
www.nature.com/articles/s41...
September 18, 2026 at 3:36 AM
🧬 Our “Behind the Paper” is now online at Nature Communities:
“Active chromatin is not simply open—it forms compact domains that cohesin keeps from mixing.”
📖 A short story behind our recent @natgenet.nature.com paper.
communities.springernature.com/posts/active...
www.nature.com/articles/s41...
“Active chromatin is not simply open—it forms compact domains that cohesin keeps from mixing.”
📖 A short story behind our recent @natgenet.nature.com paper.
communities.springernature.com/posts/active...
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Interpreting human genetic variation at atomic resolution.
A Perspective by Michael T. Zimmermann & Raul Urrutia.
⬇️
www.nature.com/articles/s41...
📰Interpreting human genetic variation at atomic resolution.
A Perspective by Michael T. Zimmermann & Raul Urrutia.
⬇️
www.nature.com/articles/s41...
Interpreting human genetic variation at atomic resolution - Nature Genetics
This Perspective discusses computational structural genomics, a conceptual framework that links genetic variants to three-dimensional molecular structures and their dynamics and function in a cellular...
www.nature.com
September 21, 2026 at 2:09 PM
📢OUT TODAY @natgenet.nature.com
📰Interpreting human genetic variation at atomic resolution.
A Perspective by Michael T. Zimmermann & Raul Urrutia.
⬇️
www.nature.com/articles/s41...
📰Interpreting human genetic variation at atomic resolution.
A Perspective by Michael T. Zimmermann & Raul Urrutia.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Genetic landscape of an in vivo protein interactome.
By Savandara Besse, Adrian W. R. Serohijos and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genetic landscape of an in vivo protein interactome.
By Savandara Besse, Adrian W. R. Serohijos and colleagues.
⬇️
www.nature.com/articles/s41...
Genetic landscape of an in vivo protein interactome - Nature Genetics
This study uses budding yeast as a model system to link genetic variants with quantitative changes in protein–protein interaction strength under different environmental perturbations by leveraging a p...
www.nature.com
September 21, 2026 at 2:04 PM
📢OUT TODAY @natgenet.nature.com
📰Genetic landscape of an in vivo protein interactome.
By Savandara Besse, Adrian W. R. Serohijos and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genetic landscape of an in vivo protein interactome.
By Savandara Besse, Adrian W. R. Serohijos and colleagues.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Pan-genome-based resequencing of 2,320 accessions reveals structural variations and accelerates breeding advances in cultivated peanut.
By Yiyang Liu, Shubo Wan and colleagues.
⬇️
www.nature.com/articles/s41...
📰Pan-genome-based resequencing of 2,320 accessions reveals structural variations and accelerates breeding advances in cultivated peanut.
By Yiyang Liu, Shubo Wan and colleagues.
⬇️
www.nature.com/articles/s41...
Pan-genome-based resequencing of 2,320 accessions reveals structural variations and accelerates breeding advances in cultivated peanut - Nature Genetics
Pan-genome analyses of cultivated peanut using 10 newly assembled genomes, along with whole-genome resequencing of 2,320 germplasm accessions, highlight structural variations and loci associated with ...
www.nature.com
September 15, 2026 at 12:10 PM
📢OUT TODAY @natgenet.nature.com
📰Pan-genome-based resequencing of 2,320 accessions reveals structural variations and accelerates breeding advances in cultivated peanut.
By Yiyang Liu, Shubo Wan and colleagues.
⬇️
www.nature.com/articles/s41...
📰Pan-genome-based resequencing of 2,320 accessions reveals structural variations and accelerates breeding advances in cultivated peanut.
By Yiyang Liu, Shubo Wan and colleagues.
⬇️
www.nature.com/articles/s41...
📢OUT TODAY @natgenet.nature.com
📰Type 1 interferon perturbates clonal competition by reshaping human blood development.
By Chhiring Lama, Anna Nam and colleagues.
⬇️
www.nature.com/articles/s41...
📰Type 1 interferon perturbates clonal competition by reshaping human blood development.
By Chhiring Lama, Anna Nam and colleagues.
⬇️
www.nature.com/articles/s41...
Type 1 interferon perturbates clonal competition by reshaping human blood development - Nature Genetics
Single-cell multiomics of blood stem cells from patients with myeloproliferative neoplasms revealed that interferon-α normalizes blood counts by augmenting lymphoid differentiation and modulates clona...
www.nature.com
September 15, 2026 at 12:08 PM
📢OUT TODAY @natgenet.nature.com
📰Type 1 interferon perturbates clonal competition by reshaping human blood development.
By Chhiring Lama, Anna Nam and colleagues.
⬇️
www.nature.com/articles/s41...
📰Type 1 interferon perturbates clonal competition by reshaping human blood development.
By Chhiring Lama, Anna Nam and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Contribution of copy number variants to schizophrenia in East Asian populations.
By Yu Chen, Hailiang Huang and colleagues.
⬇️
www.nature.com/articles/s41...
📰Contribution of copy number variants to schizophrenia in East Asian populations.
By Yu Chen, Hailiang Huang and colleagues.
⬇️
www.nature.com/articles/s41...
Contribution of copy number variants to schizophrenia in East Asian populations - Nature Genetics
Genomic analyses in populations of East Asian ancestry identify rare copy number variants associated with schizophrenia. Meta-analyses with populations of European ancestry identify additional risk lo...
www.nature.com
September 14, 2026 at 3:07 PM
📢PUBLISHED @natgenet.nature.com
📰Contribution of copy number variants to schizophrenia in East Asian populations.
By Yu Chen, Hailiang Huang and colleagues.
⬇️
www.nature.com/articles/s41...
📰Contribution of copy number variants to schizophrenia in East Asian populations.
By Yu Chen, Hailiang Huang and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Cohesin prevents local mixing of condensed euchromatic domains in living human cells.
By Masa A. Shimazoe, Kazuhiro Maeshima and colleagues.
⬇️
www.nature.com/articles/s41...
📰Cohesin prevents local mixing of condensed euchromatic domains in living human cells.
By Masa A. Shimazoe, Kazuhiro Maeshima and colleagues.
⬇️
www.nature.com/articles/s41...
Cohesin prevents local mixing of condensed euchromatic domains in living human cells - Nature Genetics
Single-nucleosome imaging/tracking and super-resolution three-dimensional structured illumination microscopy within euchromatic regions show that cohesin-mediated loops constrain condensed euchromatic...
www.nature.com
September 14, 2026 at 3:05 PM
📢PUBLISHED @natgenet.nature.com
📰Cohesin prevents local mixing of condensed euchromatic domains in living human cells.
By Masa A. Shimazoe, Kazuhiro Maeshima and colleagues.
⬇️
www.nature.com/articles/s41...
📰Cohesin prevents local mixing of condensed euchromatic domains in living human cells.
By Masa A. Shimazoe, Kazuhiro Maeshima and colleagues.
⬇️
www.nature.com/articles/s41...
📢 @natgenet.nature.com September issue's out!
Featuring:
✅myeloid cells in AD
✅multiple sclerosis multiancestry GWAS & multiomics
✅functional AI-designed enhancers in mice
✅hPTMs cross species profiling with iChIP2
✅data integration with SCIGMA
and much more!
⬇️
www.nature.com/ng/volumes/5...
Featuring:
✅myeloid cells in AD
✅multiple sclerosis multiancestry GWAS & multiomics
✅functional AI-designed enhancers in mice
✅hPTMs cross species profiling with iChIP2
✅data integration with SCIGMA
and much more!
⬇️
www.nature.com/ng/volumes/5...
September 14, 2026 at 3:02 PM
📢 @natgenet.nature.com September issue's out!
Featuring:
✅myeloid cells in AD
✅multiple sclerosis multiancestry GWAS & multiomics
✅functional AI-designed enhancers in mice
✅hPTMs cross species profiling with iChIP2
✅data integration with SCIGMA
and much more!
⬇️
www.nature.com/ng/volumes/5...
Featuring:
✅myeloid cells in AD
✅multiple sclerosis multiancestry GWAS & multiomics
✅functional AI-designed enhancers in mice
✅hPTMs cross species profiling with iChIP2
✅data integration with SCIGMA
and much more!
⬇️
www.nature.com/ng/volumes/5...
📢PUBLISHED @natgenet.nature.com
📰Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects.
By Siyang Liu, Fengxiang Wei and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects.
By Siyang Liu, Fengxiang Wei and colleagues.
⬇️
www.nature.com/articles/s41...
Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects - Nature Genetics
Genome-wide analyses in up to 121,579 pregnant women from China identify genetic associations across 111 phenotypes, including gestation-specific effects and interactions with gestational timing.
www.nature.com
July 28, 2026 at 2:56 PM
📢PUBLISHED @natgenet.nature.com
📰Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects.
By Siyang Liu, Fengxiang Wei and colleagues.
⬇️
www.nature.com/articles/s41...
📰Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects.
By Siyang Liu, Fengxiang Wei and colleagues.
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www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants.
By Liudan Jiang, Chuan He and colleagues.
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www.nature.com/articles/s41...
📰Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants.
By Liudan Jiang, Chuan He and colleagues.
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www.nature.com/articles/s41...
Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants - Nature Genetics
Intrinsically disordered regions impose regulatory restraints on gene-activating demethylases, limiting chromatin engagement and preserving genomic stability. This function is a key determinant of the...
www.nature.com
July 28, 2026 at 2:54 PM
📢PUBLISHED @natgenet.nature.com
📰Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants.
By Liudan Jiang, Chuan He and colleagues.
⬇️
www.nature.com/articles/s41...
📰Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants.
By Liudan Jiang, Chuan He and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber.
By Jiantao Guan, Shengping Zhang and colleagues.
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www.nature.com/articles/s41...
📰Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber.
By Jiantao Guan, Shengping Zhang and colleagues.
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www.nature.com/articles/s41...
Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber - Nature Genetics
Pangenome analyses of chromosome-scale genome assemblies for 125 diverse cucumber accessions highlight structural variation shaped by selection for geographical adaptation, fruit-length diversificatio...
www.nature.com
July 28, 2026 at 2:52 PM
📢PUBLISHED @natgenet.nature.com
📰Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber.
By Jiantao Guan, Shengping Zhang and colleagues.
⬇️
www.nature.com/articles/s41...
📰Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber.
By Jiantao Guan, Shengping Zhang and colleagues.
⬇️
www.nature.com/articles/s41...
📢PUBLISHED @natgenet.nature.com
📰SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry.
By Brian J. Liddicoat, Jesse J. Balic, @mafdawson.bsky.social and colleagues.
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www.nature.com/articles/s41...
📰SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry.
By Brian J. Liddicoat, Jesse J. Balic, @mafdawson.bsky.social and colleagues.
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www.nature.com/articles/s41...
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry - Nature Genetics
This study uses a highly selective inhibitor to elucidate DNMT1’s specific functions and their regulation. Notably, RFN4-mediated SUMOylation enhances DNMT1 mobility and DNA methylation, thereby promo...
www.nature.com
July 28, 2026 at 2:49 PM
📢PUBLISHED @natgenet.nature.com
📰SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry.
By Brian J. Liddicoat, Jesse J. Balic, @mafdawson.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
📰SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry.
By Brian J. Liddicoat, Jesse J. Balic, @mafdawson.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...