Nature Protocols
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New Article! Kit-based remote collection and isolation of human reprogrammable somatic cells for generation of induced pluripotent stem cells and cerebral organoids
Kit-based remote collection and isolation of human reprogrammable somatic cells for generation of induced pluripotent stem cells and cerebral organoids
Nature Protocols, Published online: 16 September 2026; doi:10.1038/s41596-026-01440-zThis protocol reliably generates induced pluripotent stem cells derived from hair follicle keratinocytes.
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September 17, 2026 at 8:16 AM
New Article! Kit-based remote collection and isolation of human reprogrammable somatic cells for generation of induced pluripotent stem cells and cerebral organoids
Last chance to register for Reframing Precision Medicine: Innovation to Implementation, a flagship Nature Conference in London from 13–15 Oct 2026. Learn more at go.nature.com/471AdQb
Reframing Precision Medicine: Innovation to Implementation | 13–15 October 2026
A Nature conference reimagining what it means to deliver truly personalised care in the next decade.
go.nature.com
September 16, 2026 at 8:32 AM
Last chance to register for Reframing Precision Medicine: Innovation to Implementation, a flagship Nature Conference in London from 13–15 Oct 2026. Learn more at go.nature.com/471AdQb
New Article! Quantitative imaging of dynamic processes in intestinal organoids
Quantitative imaging of dynamic processes in intestinal organoids
Nature Protocols, Published online: 15 September 2026; doi:10.1038/s41596-026-01432-zWe present a Protocol for long-term imaging of intestinal organoids, in combination with OrganoidTracker software, that enables both single-cell tracking analysis for use in dynamic cell type inference and fluorescence intensity measurements.
dlvr.it
September 15, 2026 at 1:33 PM
New Article! Quantitative imaging of dynamic processes in intestinal organoids
New Article! Generation of eight-cell embryo-like cells from human pluripotent stem cells
Generation of eight-cell embryo-like cells from human pluripotent stem cells
Nature Protocols, Published online: 11 September 2026; doi:10.1038/s41596-026-01414-1This protocol describes the generation of eight-cell embryo-like cells (8CLCs) from human pluripotent stem cells. The resulting 8CLCs exhibit transcriptional and epigenetic features resembling those of human 8C embryo cells.
dlvr.it
September 11, 2026 at 4:08 PM
New Article! Generation of eight-cell embryo-like cells from human pluripotent stem cells
New Article! Probing and controlling Cu catalyst reconstruction during CO2 electroreduction
Probing and controlling Cu catalyst reconstruction during CO2 electroreduction
Nature Protocols, Published online: 11 September 2026; doi:10.1038/s41596-026-01430-1Copper-based catalysts undergo structural changes during the course of the chemical reaction. This protocol describes how to use in situ/operando analysis using Raman, IR, XPS and XRD to understand Cu reconstruction during CO2 electroreduction.
dlvr.it
September 11, 2026 at 4:08 PM
New Article! Probing and controlling Cu catalyst reconstruction during CO2 electroreduction
New Article! netneurotools: a trainee-oriented approach to network neuroscience
netneurotools: a trainee-oriented approach to network neuroscience
Nature Protocols, Published online: 09 September 2026; doi:10.1038/s41596-026-01446-7This is a Perspective covering a Python toolbox for neuroscience research that enables users to fetch datasets, construct networks and null models, estimate graph metrics, fit statistical models and visualize brain images.
dlvr.it
September 9, 2026 at 4:07 PM
New Article! netneurotools: a trainee-oriented approach to network neuroscience
Hannah's looking forward to attending "Reframing Precision Medicine: Innovation to Implementation" in London next month, to learn more about how multi omics, AI & big data can move personalised care from promise to practice. Find out more at: go.nature.com/471AdQb
Reframing Precision Medicine: Innovation to Implementation | 13–15 October 2026
A Nature conference reimagining what it means to deliver truly personalised care in the next decade.
go.nature.com
September 9, 2026 at 8:43 AM
Hannah's looking forward to attending "Reframing Precision Medicine: Innovation to Implementation" in London next month, to learn more about how multi omics, AI & big data can move personalised care from promise to practice. Find out more at: go.nature.com/471AdQb
New Article! Dopamine polymerization-mediated surface functionalization of living cells for advanced therapeutic applications
Dopamine polymerization-mediated surface functionalization of living cells for advanced therapeutic applications
Nature Protocols, Published online: 04 September 2026; doi:10.1038/s41596-026-01422-1Here the authors provide a flexible and versatile protocol for surface functionalization of living cells through in situ dopamine polymerization that allows personalized living cells to be designed with customizable functions by tuning the surface components.
dlvr.it
September 4, 2026 at 4:37 PM
New Article! Dopamine polymerization-mediated surface functionalization of living cells for advanced therapeutic applications
New Article! VINE-seq and MultiVINE-seq for single-nucleus and multiome profiling of the brain vasculature
VINE-seq and MultiVINE-seq for single-nucleus and multiome profiling of the brain vasculature
Nature Protocols, Published online: 03 September 2026; doi:10.1038/s41596-026-01434-xThe cell types forming the blood–brain barrier are underrepresented in existing single-cell studies. This protocol describes the isolation of cerebral vessels and subsequent enzymatic extraction of high-purity nuclei for downstream multiomics.
dlvr.it
September 3, 2026 at 4:07 PM
New Article! VINE-seq and MultiVINE-seq for single-nucleus and multiome profiling of the brain vasculature
New Article! Salt-assisted synthesis of high phase-purity metastable 1T′-phase group VIB transition metal dichalcogenides
Salt-assisted synthesis of high phase-purity metastable 1T′-phase group VIB transition metal dichalcogenides
Nature Protocols, Published online: 01 September 2026; doi:10.1038/s41596-026-01429-8The physicochemical properties of transition metal dichalcogenides strongly depend on their crystal phases. This Protocol describes a salt-assisted synthesis of metastable 1T′-transition metal dichalcogenide crystals with high crystalline quality and high phase purity.
dlvr.it
September 1, 2026 at 5:37 PM
New Article! Salt-assisted synthesis of high phase-purity metastable 1T′-phase group VIB transition metal dichalcogenides
New Article! Shear-flow-induced assembly of 2D nanosheets for the fabrication of composite films with high tensile strength
Shear-flow-induced assembly of 2D nanosheets for the fabrication of composite films with high tensile strength
Nature Protocols, Published online: 28 August 2026; doi:10.1038/s41596-026-01442-xWe present a protocol for the fabrication of highly ordered composite films in which 2D nanosheets can be aligned and fixed, yielding high tensile strength and suitability for high-performance wearable electronics.
dlvr.it
August 28, 2026 at 10:06 AM
New Article! Shear-flow-induced assembly of 2D nanosheets for the fabrication of composite films with high tensile strength
New Article! Preparation of polycaprolactone-based 2D platelets via living crystallization-driven self-assembly
Preparation of polycaprolactone-based 2D platelets via living crystallization-driven self-assembly
Nature Protocols, Published online: 25 August 2026; doi:10.1038/s41596-026-01428-9Uniform two-dimensional platelets made from synthetic polymers can range in size from 100 nm to several micrometers and have diverse applications. This Protocol describes the synthesis and crystallization-driven self-assembly of poly(ε-caprolactone)-based polymers.
dlvr.it
August 25, 2026 at 1:22 PM
New Article! Preparation of polycaprolactone-based 2D platelets via living crystallization-driven self-assembly
New Article! Synthesis of radioafterglow nanoprobes for deep-tissue imaging of hydrogen peroxide
Synthesis of radioafterglow nanoprobes for deep-tissue imaging of hydrogen peroxide
Nature Protocols, Published online: 24 August 2026; doi:10.1038/s41596-026-01421-2This protocol is for the synthesis of radioafterglow nanoprobes that convert X-ray energy to near-infrared emissions with long half-life and high brightness, detectable from up to 15-cm depth.
dlvr.it
August 24, 2026 at 4:06 PM
New Article! Synthesis of radioafterglow nanoprobes for deep-tissue imaging of hydrogen peroxide
New Article! Selective heavy-metal sequestration and rare-earth element recovery using metal–organic frameworks
Selective heavy-metal sequestration and rare-earth element recovery using metal–organic frameworks
Nature Protocols, Published online: 24 August 2026; doi:10.1038/s41596-026-01425-yMetal adsorption using metal–organic frameworks is a good way to remove and recover heavy or rare-earth metals from water in the environment. This protocol describes their design as well as assays to characterize their stability and performance.
dlvr.it
August 24, 2026 at 1:07 PM
New Article! Selective heavy-metal sequestration and rare-earth element recovery using metal–organic frameworks
Reposted by Nature Protocols
An orange-tailed marsh dart damselfly peering through a leaf has won the 2026 BMC Ecology and Evolution and BMC Zoology image competition. The annual contest showcases the beauty of biodiversity and the science behind its conservation: spklr.io/63325ERtjJ
#envecon #biodiversity
#envecon #biodiversity
August 20, 2026 at 3:35 PM
An orange-tailed marsh dart damselfly peering through a leaf has won the 2026 BMC Ecology and Evolution and BMC Zoology image competition. The annual contest showcases the beauty of biodiversity and the science behind its conservation: spklr.io/63325ERtjJ
#envecon #biodiversity
#envecon #biodiversity
New Article! Centralized processing of frozen tumor tissues for global cancer genomics
Centralized processing of frozen tumor tissues for global cancer genomics
Nature Protocols, Published online: 17 August 2026; doi:10.1038/s41596-026-01426-xThis Protocol outlines a pathologist-led, centralized workflow for processing frozen tumor tissues to generate high-quality DNA for whole-genome sequencing. It integrates cryosectioning, digital pathology, macrodissection and laser microdissection to enrich tumor content and automated DNA extraction.
dlvr.it
August 17, 2026 at 1:06 PM
New Article! Centralized processing of frozen tumor tissues for global cancer genomics
New Article! Using MetaboAnalyst 6.0 for exposomics data analysis—from LC–MS2 spectra processing to dose–response modeling and causal inference
Using MetaboAnalyst 6.0 for exposomics data analysis—from LC–MS2 spectra processing to dose–response modeling and causal inference
Nature Protocols, Published online: 17 August 2026; doi:10.1038/s41596-026-01415-0High-resolution liquid chromatography–tandem mass spectrometry is widely used in exposomics, for example, to study metabolomic responses to environmental exposures. This Protocol describes spectra processing, statistical analysis, dose–response modeling and causal analysis using MetaboAnalyst 6.0.
dlvr.it
August 17, 2026 at 11:18 AM
New Article! Using MetaboAnalyst 6.0 for exposomics data analysis—from LC–MS2 spectra processing to dose–response modeling and causal inference
New Article! Synthesis of diiron subcluster [Fe2[(μ-SCH2)2NH](CN)2(CO)4]2− for artificial maturation of [FeFe]-hydrogenases
Synthesis of diiron subcluster [Fe2[(μ-SCH2)2NH](CN)2(CO)4]2− for artificial maturation of [FeFe]-hydrogenases
Nature Protocols, Published online: 13 August 2026; doi:10.1038/s41596-026-01418-x[FeFe]-Hydrogenases catalyze H2 production and consumption. Their impact is limited by the complexity of the natural synthetic process. This protocol describes the synthesis of diiron subclusters to simplify the production of functional enzymes.
dlvr.it
August 13, 2026 at 3:27 PM
New Article! Synthesis of diiron subcluster [Fe2[(μ-SCH2)2NH](CN)2(CO)4]2− for artificial maturation of [FeFe]-hydrogenases
New Article! Direct printing of metasurfaces using formulated optical materials
Direct printing of metasurfaces using formulated optical materials
Nature Protocols, Published online: 11 August 2026; doi:10.1038/s41596-026-01407-0A printable composite material provides a practical and cost-effective route for fabricating metasurfaces on flexible or curved substrates, scalable from the UV to IR wavelengths and deployable for photonic devices.
dlvr.it
August 11, 2026 at 2:57 PM
New Article! Direct printing of metasurfaces using formulated optical materials
New Article! ONE microscopy
ONE microscopy
Nature Protocols, Published online: 11 August 2026; doi:10.1038/s41596-026-01399-xAn approach for combining expansion microscopy with fluctuation-based super-resolution analysis enables the visualization of individual proteins via conventional fluorescence microscopy.
dlvr.it
August 11, 2026 at 7:27 AM
New Article! ONE microscopy
New Article! Standardized assays for evaluating superoxide dismutase-like and catalase-like activities of nanozymes
Standardized assays for evaluating superoxide dismutase-like and catalase-like activities of nanozymes
Nature Protocols, Published online: 10 August 2026; doi:10.1038/s41596-026-01417-yAntioxidant nanozymes are therapeutic candidates for oxidative diseases. Here a standardized protocol is described to characterize superoxide dismutase-like or catalase-like nanozymes and quantify their activity.
dlvr.it
August 10, 2026 at 1:57 PM
New Article! Standardized assays for evaluating superoxide dismutase-like and catalase-like activities of nanozymes
New Article! Drug self-administration in head-fixed mice
Drug self-administration in head-fixed mice
Nature Protocols, Published online: 10 August 2026; doi:10.1038/s41596-026-01406-1Here, the authors provide a protocol for a head-restrained approach in mice for intravenous and oral self-administration of drug and nondrug rewards.
dlvr.it
August 10, 2026 at 1:57 PM
New Article! Drug self-administration in head-fixed mice
New Article! A general approach for the synthesis of nanoisland catalysts
A general approach for the synthesis of nanoisland catalysts
Nature Protocols, Published online: 05 August 2026; doi:10.1038/s41596-026-01431-0Stabilization of metal single-atom or cluster catalysts is achieved by forming CeOx nanoislands on SiO2 through strong electrostatic adsorption method. Transition-metal precursors are added to form single atoms or clusters on these islands.
dlvr.it
August 5, 2026 at 3:57 PM
New Article! A general approach for the synthesis of nanoisland catalysts
New Article! Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
Nature Protocols, Published online: 30 July 2026; doi:10.1038/s41596-026-01423-0Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
dlvr.it
July 30, 2026 at 12:56 PM
New Article! Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
New Article! Reply to: Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
Reply to: Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
Nature Protocols, Published online: 30 July 2026; doi:10.1038/s41596-026-01424-zReply to: Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
dlvr.it
July 30, 2026 at 12:56 PM
New Article! Reply to: Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments