Nature Reviews Disease Primers
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Nature Reviews Disease Primers publishes Primers - introductory reviews on diseases and disorders - across all medical specialties. Check back each week!
Toxidromes are clinical syndromes caused by specific toxic mechanisms following exposure to drugs, chemicals or other toxins. The epidemiology of the underlying poisonings varies globally.
http://dlvr.it/TVWDWY
http://dlvr.it/TVWDWY
September 16, 2026 at 6:30 PM
Toxidromes are clinical syndromes caused by specific toxic mechanisms following exposure to drugs, chemicals or other toxins. The epidemiology of the underlying poisonings varies globally.
http://dlvr.it/TVWDWY
http://dlvr.it/TVWDWY
Muscarinic and antimuscarinic toxidromes reflect opposite effects on cholinergic signalling: receptor activation drives parasympathetic overactivity, whereas receptor blockade suppresses it and sympathetic effects predominate.
http://dlvr.it/TVVcc9
http://dlvr.it/TVVcc9
September 16, 2026 at 5:20 AM
Muscarinic and antimuscarinic toxidromes reflect opposite effects on cholinergic signalling: receptor activation drives parasympathetic overactivity, whereas receptor blockade suppresses it and sympathetic effects predominate.
http://dlvr.it/TVVcc9
http://dlvr.it/TVVcc9
The serotonergic toxidrome results from excessive activation of serotonin receptors, particularly 5-HT₁A and 5-HT₂A receptors, driven by increased serotonin release, reduced clearance or direct receptor activation.
http://dlvr.it/TVTsnm
http://dlvr.it/TVTsnm
September 15, 2026 at 9:14 AM
The serotonergic toxidrome results from excessive activation of serotonin receptors, particularly 5-HT₁A and 5-HT₂A receptors, driven by increased serotonin release, reduced clearance or direct receptor activation.
http://dlvr.it/TVTsnm
http://dlvr.it/TVTsnm
The sympathomimetic toxidrome arises from excessive catecholamine receptor activation, typically owing to increased release or reduced clearance of neurotransmitters such as noradrenaline, adrenaline and dopamine.
http://dlvr.it/TVT7J7
http://dlvr.it/TVT7J7
September 14, 2026 at 12:34 PM
The sympathomimetic toxidrome arises from excessive catecholamine receptor activation, typically owing to increased release or reduced clearance of neurotransmitters such as noradrenaline, adrenaline and dopamine.
http://dlvr.it/TVT7J7
http://dlvr.it/TVT7J7
The opioid toxidrome results from excessive activation of opioid receptors and the characteristic features of opioid poisoning arise primarily from their effects in the central nervous system.
http://dlvr.it/TVSMzx
http://dlvr.it/TVSMzx
September 13, 2026 at 10:53 AM
The opioid toxidrome results from excessive activation of opioid receptors and the characteristic features of opioid poisoning arise primarily from their effects in the central nervous system.
http://dlvr.it/TVSMzx
http://dlvr.it/TVSMzx
Deaths from unintentional poisoning vary widely around the world, owing to differences in exposure to toxic substances and access to prevention and care.
http://dlvr.it/TVRh27
http://dlvr.it/TVRh27
September 12, 2026 at 7:17 AM
Deaths from unintentional poisoning vary widely around the world, owing to differences in exposure to toxic substances and access to prevention and care.
http://dlvr.it/TVRh27
http://dlvr.it/TVRh27
Poisoning assessment follows a structured approach including resuscitation, risk assessment and management. Identifying toxidromes is central to this process, helping clinicians tailor treatment to the cause and severity of poisoning.
http://dlvr.it/TVR73F
http://dlvr.it/TVR73F
September 11, 2026 at 1:24 PM
Poisoning assessment follows a structured approach including resuscitation, risk assessment and management. Identifying toxidromes is central to this process, helping clinicians tailor treatment to the cause and severity of poisoning.
http://dlvr.it/TVR73F
http://dlvr.it/TVR73F
Get Primed on Toxidromes with our NEW PrimeView! FREE to download this week!
Toxidromes - Nature Reviews Disease Primers
This PrimeView summarizes mechanisms, diagnosis and management of classical toxidromes - characteristic patterns of clinical features caused by poisonings with specific xenobiotics. It accompanies the Primer on this topic by Roberts et al.
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September 10, 2026 at 3:38 PM
Get Primed on Toxidromes with our NEW PrimeView! FREE to download this week!
Our NEW Primer on Toxidromes is live today! By Roberts et al.
Check it out here: www.nature.com/articles/s41...
Check it out here: www.nature.com/articles/s41...
Toxidromes - Nature Reviews Disease Primers
Toxidromes are characteristic patterns of clinical features caused by specific toxic mechanisms that support clinical management of the poisoned patient. In this Primer, Roberts et al. summarize the e...
www.nature.com
September 10, 2026 at 9:15 AM
Our NEW Primer on Toxidromes is live today! By Roberts et al.
Check it out here: www.nature.com/articles/s41...
Check it out here: www.nature.com/articles/s41...
Gliomas account for ~30% of all primary BrainTumours and 80% of malignant brain tumours, and are responsible for most deaths from primary brain tumours http://dlvr.it/TVPhRk
September 9, 2026 at 9:50 PM
Gliomas account for ~30% of all primary BrainTumours and 80% of malignant brain tumours, and are responsible for most deaths from primary brain tumours http://dlvr.it/TVPhRk
Podocytopathies can be classified according to their aetiologies into six different types, which have varying prevalence across the lifespan.
http://dlvr.it/TVN5RN
http://dlvr.it/TVN5RN
September 8, 2026 at 6:33 AM
Podocytopathies can be classified according to their aetiologies into six different types, which have varying prevalence across the lifespan.
http://dlvr.it/TVN5RN
http://dlvr.it/TVN5RN
Following primary infection, varicella zoster virus establishes latency in sensory ganglia and may reactivate later to cause herpes zoster. http://dlvr.it/TVMDVL
September 7, 2026 at 4:54 AM
Following primary infection, varicella zoster virus establishes latency in sensory ganglia and may reactivate later to cause herpes zoster. http://dlvr.it/TVMDVL
Upon reactivation from latency, varicella zoster virus travels along sensory nerves to the skin, resulting in herpes zoster (HZ). HZ presents as a spectrum of disease, most often accompanied by a localised rash. http://dlvr.it/TVM3h3
September 6, 2026 at 7:45 PM
Upon reactivation from latency, varicella zoster virus travels along sensory nerves to the skin, resulting in herpes zoster (HZ). HZ presents as a spectrum of disease, most often accompanied by a localised rash. http://dlvr.it/TVM3h3
Get Primed on Varicella zoster virus infection with our NEW PrimeView! FREE to download this week! http://dlvr.it/TVKxsF
September 5, 2026 at 1:09 AM
Get Primed on Varicella zoster virus infection with our NEW PrimeView! FREE to download this week! http://dlvr.it/TVKxsF
Our NEW Primer on Varicella zoster virus infection is live! By Nagel et al. Check it out here:
Varicella zoster virus infection - Nature Reviews Disease Primers
Primary infection of varicella zoster virus causes varicella (chickenpox). Virus reactivation later in life can cause herpes zoster (shingles) and other neurological and systemic complications. In this Primer, Bubak et al. describe the epidemiology, mechanisms, diagnosis and management of varicella zoster virus infection, and highlight patients’ quality of life and questions for future research.
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September 4, 2026 at 2:51 PM
Our NEW Primer on Varicella zoster virus infection is live! By Nagel et al. Check it out here:
This new Comment argues that patient and caregiver insights can transform basic research by revealing overlooked disease features and helping ensure that new hypotheses address clinically relevant questions. #MedSky
http://dlvr.it/TVBqtF
http://dlvr.it/TVBqtF
August 27, 2026 at 9:37 AM
This new Comment argues that patient and caregiver insights can transform basic research by revealing overlooked disease features and helping ensure that new hypotheses address clinically relevant questions. #MedSky
http://dlvr.it/TVBqtF
http://dlvr.it/TVBqtF
In 2022, the seven countries with the highest incidence of multidrug-resistant tuberculosis cases, accounted for two thirds of the entire global cases. http://dlvr.it/TVBDnZ
August 26, 2026 at 3:10 PM
In 2022, the seven countries with the highest incidence of multidrug-resistant tuberculosis cases, accounted for two thirds of the entire global cases. http://dlvr.it/TVBDnZ
LongCOVID can have serious implications for patients’ quality of life. #COVID19 http://dlvr.it/TV9Zwj
August 25, 2026 at 8:14 PM
LongCOVID can have serious implications for patients’ quality of life. #COVID19 http://dlvr.it/TV9Zwj
For neurologists who want to stay up to date but are short on time, Nature Briefing: Clinical Neurology brings together key clinical developments and research from the leading journals in a concise weekly newsletter. Sign up is free
go.springernature.com/int1/briefin...
go.springernature.com/int1/briefin...
August 25, 2026 at 2:03 PM
For neurologists who want to stay up to date but are short on time, Nature Briefing: Clinical Neurology brings together key clinical developments and research from the leading journals in a concise weekly newsletter. Sign up is free
go.springernature.com/int1/briefin...
go.springernature.com/int1/briefin...
The most prevalent type of epithelial ovarian cancer is high-grade serous ovarian cancer originating from the fimbriated ends of the ovaries http://dlvr.it/TV849z
August 24, 2026 at 2:05 AM
The most prevalent type of epithelial ovarian cancer is high-grade serous ovarian cancer originating from the fimbriated ends of the ovaries http://dlvr.it/TV849z
Schizophrenia demonstrates many aspects of a #neurodevelopmental condition, and individuals have a high genetic predisposition
http://dlvr.it/TV7ntn
http://dlvr.it/TV7ntn
August 23, 2026 at 1:52 PM
Schizophrenia demonstrates many aspects of a #neurodevelopmental condition, and individuals have a high genetic predisposition
http://dlvr.it/TV7ntn
http://dlvr.it/TV7ntn
The microanalytic cycle of insomnia explains how arousal, unhelpful thoughts, maladaptive habits and daytime consequences reinforce each other, allowing insomnia to become self sustaining and increasing the risk of ongoing sleep difficulties. http://dlvr.it/TV7QH5
August 22, 2026 at 7:02 PM
The microanalytic cycle of insomnia explains how arousal, unhelpful thoughts, maladaptive habits and daytime consequences reinforce each other, allowing insomnia to become self sustaining and increasing the risk of ongoing sleep difficulties. http://dlvr.it/TV7QH5
Get Primed on Lyme borreliosis with our NEW PrimeView! http://dlvr.it/TV6lfT
August 21, 2026 at 5:26 PM
Get Primed on Lyme borreliosis with our NEW PrimeView! http://dlvr.it/TV6lfT
#Schizophrenia demonstrates many aspects of a #neurodevelopmental condition, and individuals have a high genetic predisposition
http://dlvr.it/TV5jpp
http://dlvr.it/TV5jpp
August 20, 2026 at 1:12 PM
#Schizophrenia demonstrates many aspects of a #neurodevelopmental condition, and individuals have a high genetic predisposition
http://dlvr.it/TV5jpp
http://dlvr.it/TV5jpp
Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant bacterial pathogen that causes a wide range of infections, including skin, soft tissue, bone and bloodstream infections, and pneumonia.
http://dlvr.it/TV4qxM
http://dlvr.it/TV4qxM
August 19, 2026 at 12:38 PM
Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant bacterial pathogen that causes a wide range of infections, including skin, soft tissue, bone and bloodstream infections, and pneumonia.
http://dlvr.it/TV4qxM
http://dlvr.it/TV4qxM