Patrick Gibbs
@patrickgibbs.bsky.social
PhD Student at Cambridge University. Interested in Quantitative Genetics. Supervised by Xilin Jiang
Reposted by Patrick Gibbs
What happens when we have “sufficiently” large sample sizes?
www.medrxiv.org/content/10.6...
www.medrxiv.org/content/10.6...
Predicting COVID-19 hospitalisation and common disease risk from comorbid diagnoses in 13 million individuals
Predicting disease risk from prior diagnoses is fundamental to clinical decision-making, particularly during health emergencies such as the COVID-19 pandemic, when individuals with long-term condition...
www.medrxiv.org
September 3, 2026 at 3:15 PM
What happens when we have “sufficiently” large sample sizes?
www.medrxiv.org/content/10.6...
www.medrxiv.org/content/10.6...
Reposted by Patrick Gibbs
Roughly half of common disease heritability is pleiotropic across diseases, with shared variance 1.51x enriched in the genetic component.
Work led by Yujie Zhao (co-supervised by Alkes and me) is now out in @natgenet.nature.com
www.nature.com/articles/s41...
Work led by Yujie Zhao (co-supervised by Alkes and me) is now out in @natgenet.nature.com
www.nature.com/articles/s41...
June 15, 2026 at 11:06 AM
Roughly half of common disease heritability is pleiotropic across diseases, with shared variance 1.51x enriched in the genetic component.
Work led by Yujie Zhao (co-supervised by Alkes and me) is now out in @natgenet.nature.com
www.nature.com/articles/s41...
Work led by Yujie Zhao (co-supervised by Alkes and me) is now out in @natgenet.nature.com
www.nature.com/articles/s41...
Happy to share new manuscript I completed with @ee-reh-neh.bsky.social & @davisjmcc.bsky.social back in Melbourne. The work originally conceived by @ijbeasley.bsky.social focuses on how we can reconcile and meta-analyse eQTL studies across studies cohorts and ancestries. doi.org/10.64898/202...
February 28, 2026 at 4:24 PM
Happy to share new manuscript I completed with @ee-reh-neh.bsky.social & @davisjmcc.bsky.social back in Melbourne. The work originally conceived by @ijbeasley.bsky.social focuses on how we can reconcile and meta-analyse eQTL studies across studies cohorts and ancestries. doi.org/10.64898/202...
Reposted by Patrick Gibbs
Finally, today's offering! www.biorxiv.org/content/10.6...
This began life as a very different project which failed because we couldn't agree on defining eqtl sharing across cohorts. So two young members of the lab dug deeply into this - first @ijbeasley.bsky.social, then @patrickgibbs.bsky.social
This began life as a very different project which failed because we couldn't agree on defining eqtl sharing across cohorts. So two young members of the lab dug deeply into this - first @ijbeasley.bsky.social, then @patrickgibbs.bsky.social
www.biorxiv.org
February 28, 2026 at 6:05 AM
Finally, today's offering! www.biorxiv.org/content/10.6...
This began life as a very different project which failed because we couldn't agree on defining eqtl sharing across cohorts. So two young members of the lab dug deeply into this - first @ijbeasley.bsky.social, then @patrickgibbs.bsky.social
This began life as a very different project which failed because we couldn't agree on defining eqtl sharing across cohorts. So two young members of the lab dug deeply into this - first @ijbeasley.bsky.social, then @patrickgibbs.bsky.social
Reposted by Patrick Gibbs
Power is a major confounder in the analysis of cross-ancestry 'portability' in human eQTLs https://www.biorxiv.org/content/10.64898/2026.02.26.708346v1
February 28, 2026 at 2:35 AM
Power is a major confounder in the analysis of cross-ancestry 'portability' in human eQTLs https://www.biorxiv.org/content/10.64898/2026.02.26.708346v1
Reposted by Patrick Gibbs
Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share.
Tldr: scRNA-seq in Indonesia hard but fun
Tldr: scRNA-seq in Indonesia hard but fun
Ancestral and environmental diversity shape the immune landscape in Indonesia https://www.biorxiv.org/content/10.64898/2026.02.15.704933v1
February 16, 2026 at 7:43 AM
Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share.
Tldr: scRNA-seq in Indonesia hard but fun
Tldr: scRNA-seq in Indonesia hard but fun
Reposted by Patrick Gibbs
Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind
June 25, 2025 at 2:29 PM
Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind
I cannot recommend Davis’s group more highly! In addition to excellent research, he has been a great mentor!
📢 PostDoc opportunity in our Bioinformatics & Cellular Genomics lab at SVI! 🧬
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
Research Officer - Bioinformatics Job in Fitzroy, Melbourne VIC - SEEK
Seeking a Postdoc to develop computational toolkits to enable large-scale studies of single-cell and spatial 'omics and statistical genetics
www.seek.com.au
June 16, 2025 at 9:46 AM
I cannot recommend Davis’s group more highly! In addition to excellent research, he has been a great mentor!
Reposted by Patrick Gibbs
📢 PostDoc opportunity in our Bioinformatics & Cellular Genomics lab at SVI! 🧬
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
Research Officer - Bioinformatics Job in Fitzroy, Melbourne VIC - SEEK
Seeking a Postdoc to develop computational toolkits to enable large-scale studies of single-cell and spatial 'omics and statistical genetics
www.seek.com.au
June 16, 2025 at 7:07 AM
📢 PostDoc opportunity in our Bioinformatics & Cellular Genomics lab at SVI! 🧬
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
Very happy to share that I will soon start a PhD at Cambridge University funded by the Harding Distinguished Scholar Fellowship, supervised by @mikeinouye.bsky.social and Angela Wood. I’ll work on prediction methodologies for health trajectories, using molecular data, and Electronic Health Records.
May 28, 2025 at 9:45 AM
Very happy to share that I will soon start a PhD at Cambridge University funded by the Harding Distinguished Scholar Fellowship, supervised by @mikeinouye.bsky.social and Angela Wood. I’ll work on prediction methodologies for health trajectories, using molecular data, and Electronic Health Records.
Reposted by Patrick Gibbs
The FT reports OpenAI suspects DeepSeek of "a potential breach of intellectual property." As a columnist for NYT, which is suing OpenAI for copyright infringement, and the author of nine books OpenAI apparently used to train its model, I couldn't possibly comment. www.ft.com/content/a0df...
OpenAI says it has evidence China’s DeepSeek used its model to train competitor
White House AI tsar David Sacks raises possibility of alleged intellectual property theft
www.ft.com
January 29, 2025 at 2:06 PM
The FT reports OpenAI suspects DeepSeek of "a potential breach of intellectual property." As a columnist for NYT, which is suing OpenAI for copyright infringement, and the author of nine books OpenAI apparently used to train its model, I couldn't possibly comment. www.ft.com/content/a0df...
Very happy to share my first paper!
Here we take a look at different models for producing genomic prediction across a wide range of traits. We find that very specific conditions of where ML approaches can out preform linear regression.
Here we take a look at different models for producing genomic prediction across a wide range of traits. We find that very specific conditions of where ML approaches can out preform linear regression.
📣 New Paper out!!! 📣
When is ML outperforming good old parametric regression for genomic predictions? Go check 👇
doi.org/10.1093/gene...
When is ML outperforming good old parametric regression for genomic predictions? Go check 👇
doi.org/10.1093/gene...
Trait genetic architecture and population structure determine model selection for genomic prediction in natural Arabidopsis thaliana populations
Abstract. Genomic prediction applies to any agro- or ecologically relevant traits, with distinct ontologies and genetic architectures. Selecting the most a
doi.org
January 25, 2025 at 8:31 AM
Very happy to share my first paper!
Here we take a look at different models for producing genomic prediction across a wide range of traits. We find that very specific conditions of where ML approaches can out preform linear regression.
Here we take a look at different models for producing genomic prediction across a wide range of traits. We find that very specific conditions of where ML approaches can out preform linear regression.
Earlier this year, I was nominated and funded by unimelb to attend the Heidelberg Laureate forum in Germany. The conference connects 200 developing researchers from maths and compsci to award winning scientists inc. winners of the Fields Medal and Turing award.
It was an absolute blast!
It was an absolute blast!
December 19, 2024 at 4:57 AM
Earlier this year, I was nominated and funded by unimelb to attend the Heidelberg Laureate forum in Germany. The conference connects 200 developing researchers from maths and compsci to award winning scientists inc. winners of the Fields Medal and Turing award.
It was an absolute blast!
It was an absolute blast!
Reposted by Patrick Gibbs
Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6
A ‘Second Tree of Life’ Could Wreak Havoc, Scientists Warn (Gift Article)
Research on so-called mirror cells, which defy fundamental properties of living organisms, should be prohibited as too dangerous, biologists said.
nyti.ms
December 12, 2024 at 8:04 PM
Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6