Petar Pajic
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petarpajic.bsky.social
Petar Pajic
@petarpajic.bsky.social
NSF Postdoctoral Fellow
Yale University | Malaker Lab
Evolutionary Genetics | Glycoproteomics
Structural Variants | Mucins
Reposted by Petar Pajic
Aguado et al. investigate the salivary proline-rich protein gene family across 27 primate species to test whether dietary ecology has shaped the evolution of this locus.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Multiscale structural evolution of proline-rich protein genes shapes primate salivary defenses
Abstract. Saliva forms the first biochemical interface with the environment, mediating dietary exposure and oral defense. Proline-rich proteins in saliva p
academic.oup.com
October 7, 2026 at 3:00 PM
Our new paper is out in MBE @molbioevol.bsky.social !

Another example of how diet can shape genomes. Led by @willaguado.bsky.social!

Salivary protein genes were repeatedly reshaped, including independently evolved histidine-rich repeats linked to folivory.

doi.org/10.1093/molb...
Multiscale structural evolution of proline-rich protein genes shapes primate salivary defenses
Abstract. Saliva forms the first biochemical interface with the environment, mediating dietary exposure and oral defense. Proline-rich proteins (PRPs) in s
doi.org
September 2, 2026 at 2:59 PM
Reposted by Petar Pajic
Pajic & @gokcumenlab.bsky.social synthesize the evolution of VNTRs in mammals, including mutational mechanisms and selective forces driving their evolution, and propose a theoretical framework for their persistence through evolutionary tradeoffs.

🔗 doi.org/10.1093/gbe/evaf250

#genome #evolution
Evolutionary Balancing of Genetic Consequence and Innovation in Mammals Through Variable Number Tandem Repeats
Abstract. Understanding genomic function has historically relied on sequence conservation across evolutionary time. However, advances in genomics have reve
doi.org
January 20, 2026 at 10:38 AM