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thejournalofpain.bsky.social
The Journal of Pain
@thejournalofpain.bsky.social
89 followers 6 following 340 posts
The Journal of Pain is the official journal of ‪@usasp.bsky.social
The journal publishes original articles related to all aspects of pain.
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thejournalofpain.bsky.social
Focus: Drs. Weisman & Masharawi argue that chronic pain diagnostics should be realigned with nociceptive biology, using existing and emerging tools to detect physiologic nociceptive pathology even when structural imaging is normal.

FREE: www.jpain.org/article/S152...
When imaging is normal, but biology is not: Aligning diagnostics of pain states with nociceptive biology
Pain is the leading reason people seek medical care. Yet, the diagnosis of acute and chronic pain states remains tied to a structural paradigm that equates real disease with visible anatomical…
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October 9, 2026 at 12:30 PM
thejournalofpain.bsky.social
Review: Drs. Lu, Meng, et al. conducted a systematic review and meta-analysis to explore the influence of different prescription parameters on pain and functional improvement in pregnancy-related pregnancy-related pelvic girdle pain.

FULL: www.jpain.org/article/S152...
Exploring exercise prescription parameters for pregnancy-related pelvic girdle pain: A systematic review and meta-analysis of effects on pain and function
Exercise is recommended for pregnancy-related pelvic girdle pain (PGP), while consensus on specific prescription parameters remains uncertain. We conducted a systematic review and meta-analysis of…
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October 8, 2026 at 4:30 PM
thejournalofpain.bsky.social
Review: Drs. Brink, Dirckx et al. ( @rdo-erasmusmc.bsky.social) reviewed intravenous ketamine as an option for complex regional pain syndrome

—standardized outcome reporting and validated predictors are needed before treatment can be reliably individualized

FREE: www.jpain.org/article/S152...
Intravenous ketamine for complex regional pain syndrome: Pain outcomes and predictors of response. A systematic review and meta‑analysis
Intravenous ketamine is used for complex regional pain syndrome (CRPS), but variable response and uncertain durability limit patient selection. This systematic review evaluated reported predictors of…
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October 8, 2026 at 12:30 PM
thejournalofpain.bsky.social
Review: A study by Drs. Msigwa, Wang et al. reveal structural & functional changes across striatal, limbic, brainstem and sensorimotor–cerebellar networks in PD-related pain, supporting a network-based view of pain in Parkinson’s disease

Full: www.jpain.org/article/S152...
Neuroimaging correlates of pain in Parkinson’s disease: A systematic review of structural and resting-state fMRI studies
Chronic pain is a common non-motor symptom in Parkinson’s disease (PD), but its central neural mechanisms are not fully understood. Structural and resting-state functional MRI offer non-invasive…
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October 6, 2026 at 12:30 PM
thejournalofpain.bsky.social
Are you ready? 👀 The United States Association for the Study of Pain (USASP) 2027 Symposia submission deadline is next Monday, Oct 12th at 11:59pm Eastern! 🕰️

See the full call HERE: www.usasp.org/callforsympo...
2027 Call for Symposia | USASP
Representing scientists nationwide who collaboratively research, diagnose, and treat pain in the United States.
www.usasp.org
October 5, 2026 at 4:30 PM
thejournalofpain.bsky.social
Featured: Drs. Slater, Briggs, et al. considered how, as a community, we can strengthen person-centred equitable care with and for young people experiencing comorbid chronic pain and mental health conditions.

FREE: www.jpain.org/article/S152...
When one plus one doesn’t equal two: A commentary on strengthening the care of young people experiencing comorbid chronic pain and mental health conditions
Chronic pain and mental health conditions are often conceptualised and communicated to young people, and others, as totally separate entities. Taken together however, ‘one plus one does not equal…
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October 5, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Romain, Smolderen, et al. @yaleschoolofmed.bsky.social described pain patterns and examined its association with peripheral artery disease (PAD) severity and psychological factors in 1263 patients initiating PAD care using the PORTRAIT registry

FULL: www.jpain.org/article/S152...
Patients’ pain experience in claudication: Biopsychosocial correlates of frequency, intensity, sleep interference, and chronic pain
Pain is the hallmark symptom of claudication, the early stage of peripheral artery disease (PAD), yet its relationship with psychological distress remains unclear. We described pain patterns and…
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September 30, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: How closely do patients and physiotherapists agree on perceived improvement? Using the Global Perceived Effect scale, Ebrahimi, Dr. Gazzi Macedo et al. ( @mcmasteruniversity.bsky.social) found moderate agreement

FREE: www.jpain.org/article/S152...
What factors influence ratings of Global Perceived Effect by individuals with low back pain and physiotherapists?
The Global Perceived Effect (GPE) scale is widely used to evaluate perceived improvement in individuals with low back pain (LBP). However, factors that influence GPE ratings by patients and…
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September 29, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Duijzings, Todd, et al. @sydney.edu.au examined the psychometric properties of multiple interpretation bias measures in individuals with chronic pain and healthy controls (N=451; N=235 chronic pain, N=188 healthy)

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Psychometric evaluation of interpretation bias measures for pain
Negative interpretation bias, the tendency to interpret ambiguous information in a threatening way, is thought to play an important role in the experience and maintenance of chronic pain. However,…
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September 28, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. @emmafisherphd.bsky.social, Eccleston, et al. aimed to disentangle caregiver protectiveness of children and adolescents with pain between pain state (acute, chronic, and no pain) and context (sports, schoolwork, chores, social events)

FREE: www.jpain.org/article/S152...
How does caregiver protectiveness change between pain states and across different contexts? A vignette study of expected responses to pain
Greater caregiver protectiveness is often associated with poorer outcomes in children and adolescents with pain. However, there is a lack of understanding about the specific contexts of where…
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September 25, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Chandra, Dear et al. found that no demographic or clinical predictors were found in pain management for endometriosis, but higher baseline psychological symptoms predicted response

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The endometriosis pain course: Exploring predictors of clinical response to an internet-delivered psychological pain management program for endometriosis
Emerging research indicates the potential of psychological pain management programs to address disability and distress associated with endometriosis-related pain. Understanding the characteristics of…
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September 24, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Aguilar, Wells et al. ( @drkristenwells.bsky.social) found that a culturally and linguistically adapted Mexican Spanish version of the Pain Self-Efficacy Questionnaire is reliable and valid for Spanish-speaking Mexican Americans with chronic pain

FREE: www.jpain.org/article/S152...
A psychometric assessment of a new Spanish version of the pain self efficacy questionnaire (PSEQ) adapted for Spanish-speaking Mexican Americans
Chronic pain affects millions of people in the United States (U.S.), with Latinx individuals facing higher risks due to chronic illness, manual labor jobs, and limited access to healthcare and…
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September 23, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Alejandro, Bulls, et al. @pittdeptofmed.bsky.social examined how patients with advanced cancer and their support people perceive barriers to opioid access, how those barriers affect their cancer pain management, and more.

FREE: www.jpain.org/article/S152...
“A lot of bureaucracy”: Structural barriers to prescription opioids in cancer pain management
Well-intentioned policies to reduce opioid prescribing can conflict with efforts to manage advanced cancer pain, resulting in structural barriers to opioid pain management that complicate the…
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September 22, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. VonKorff, DeBar, et al. @kaiser-permanente.bsky.social assessed the impact of cognitive behaviorally-based self-management interventions on sustained HICP and on favorable chronic pain outcomes (mild or discontinued chronic pain).

FULL: www.jpain.org/article/S152...
Effect of self-management interventions on high impact chronic pain prevalence
Among persons with High Impact Chronic Pain (HICP), we assessed the impact of cognitive behaviorally-based self-management interventions on sustained HICP and on favorable chronic pain outcomes (mild…
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September 21, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Ye, Wu, & col. investigated brain network alterations in patients with CPSP after thalamic stroke and explored whether these changes underlie clinical symptoms.

FULL: www.jpain.org/article/S152...
Structural network dysfunction and aberrant SC-FC coupling correlate with central post-stroke pain of thalamic origin
Central post-stroke pain (CPSP) of thalamic origin is one of the most frequent subtypes in all kinds of CPSP, and often be refractory to treatments and affect the long-term prognosis of thalamic…
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September 18, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Swift, Damaj & coll. found that α7-nicotinic receptors in myeloid cells are critical for attenuating neuropathic and chronic inflammatory pain.

—new potential target for the pain treatment

Full: www.jpain.org/article/S152...
A critical role for α7 nicotinic acetylcholine receptor signaling in myeloid lineage cells in chronic neuropathic and inflammatory pain responses
Neuroinflammation influences the development of chronic pain, an increasingly prevalent condition impacting the lives of many worldwide. Given the challenges of managing chronic pain, it is essential…
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September 17, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Yuan, Tang et al. presented a novel noninvasive imaging to visualize pain in mice, based on calcium-dependent bioluminescence to potentially be used in high-throughput screening of analgesics

Full: www.jpain.org/article/S152...
Illuminating ongoing pain in mice with novel bioluminescent imaging
Objectively measuring pain in laboratory animals is essential for pain research and analgesic development. Despite the development of various behavioral tests to measure evoked pain in animal models,…
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September 16, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. McKibben, Linnstaedt et al. found that chronic pain responses after traumatic stress are sex-dependent:

—Higher early CRP predicted lower pain severity in men, suggesting sex-specific effects of inflammation on pain recovery

Full: www.jpain.org/article/S152...
Peritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner
Chronic pain following traumatic stress exposure (TSE) is common. Increasing evidence suggests inflammatory and immune mechanisms are activated following TSE, play a role in the transition from acute…
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September 15, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Artacho-Cordón, Cendán, et al. @universidadgranada.bsky.social investigated whether σ1R blockade potentiates the antinociceptive effects of µ-opioid agonists in a well-established model of capsaicin-induced visceral pain in mice.

FULL: www.jpain.org/article/S152...
New strategy for treating visceral pain: Enhancing opioid antinociception by Sigma-1 receptor inhibition
Visceral pain remains a major clinical challenge, often resistant to conventional analgesics. Sigma-1 receptor (σ1R) antagonists enhance opioid antinociception in somatic and neuropathic pain, yet…
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September 14, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Can diet quality influence pain? A UK Biobank study conducted by Drs. Elma, Macfarlane et al. ( @uniofaberdeen.bsky.social) found healthier dietary patterns were associated with lower odds of chronic pain, with associations varying by pain type

FREE: www.jpain.org/article/S152...
The association between diverse dietary quality measures and the presence of acute or chronic pain in the UK Biobank
Chronic pain affects approximately 20% of adults worldwide and is a leading cause of disability. Emerging evidence suggest that nutrition may influence pain perception. However, the association…
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September 11, 2026 at 12:30 PM
thejournalofpain.bsky.social
Review: Drs. Bosma, Rosenbloom, et al. @wchospital.bsky.social performed a systematic review of non-randomized studies aims to describe available psychotherapeutic interventions that concurrently target chronic pain and trauma-related symptoms for adults.

FULL: www.jpain.org/article/S152...
Treating pain and trauma: A systematic review of non-randomized studies of psychotherapeutic approaches
The co-occurrence of chronic pain and trauma symptoms is prevalent; thus treatment approaches that address both are required. This systematic review of non-randomized studies aims to describe…
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September 10, 2026 at 12:30 PM
thejournalofpain.bsky.social
Review: A scoping review of 175 studies led by Drs. Bond, @neiloconnell.bsky.social et al. found emerging evidence of altered sensory, motor and body perception processing in chronic pelvic pain, but major gaps remain

FREE:https://www.jpain.org/article/S1526-5900(26)00161-6/fulltext
https://www.jpain.org/article/S1526-5900(26)00161-6/fulltext
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September 9, 2026 at 12:30 PM
thejournalofpain.bsky.social
Featured: Drs. Mugglestone, Hughes ( @plymuni.bsky.social) investigated the reliability of the early temporal dynamics and late-phase expression of high-frequency stimulation-induced changes in mechanical pinprick sensitivity.

FULL: www.jpain.org/article/S152...
Temporal changes in mechanical pin prick sensitivity following high frequency induced sensitisation of central nociceptive pathways: A test re-test reliability study
High-frequency stimulation (HFS) is a human surrogate model of secondary hyperalgesia and a key experimental tool for understanding the mechanisms and modulation of central nociceptive pathways. An…
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September 8, 2026 at 6:00 PM
thejournalofpain.bsky.social
Original: Drs. Aroke, Goodin, et al. @washumedicine.bsky.social examined whether individualized racism and structural racism mediate racial disparities in nonspecific chronic low back pain outcomes among non-Hispanic Blacks and non-Hispanic Whites.

FULL: www.jpain.org/article/S152...
Structural and individualized racism drives racial disparities in chronic low back pain: A cross-sectional serial mediation analysis
This cross-sectional study examined whether individualized racism, as measured by experiences of discrimination, internalized stigma of chronic pain, and perceived injustice, as well as structural…
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August 26, 2026 at 12:30 PM
thejournalofpain.bsky.social
Original: Drs. Mu, Prather et al. observed bidirectionality between sleep health and less night pain in daily life in adults with rheumatoid arthritis

—sleep quality and duration are associated with pain in adults with rheumatoid arthritis

Full: www.jpain.org/article/S152...
Bidirectional associations between daily sleep and pain severity in adults with rheumatoid arthritis: A daily diary and actigraphy study
Poor sleep and pain are common in rheumatoid arthritis (RA). This study sought to understand the temporal relationships between multidimensional sleep and pain in daily life among individuals with…
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August 25, 2026 at 12:30 PM