Tobias Kube
@tobikube.bsky.social
Professor of Clinical Psychology and Experimental Psychopathology at Uni Frankfurt. Head of the Emmy Noether Group for Experimental Research on Depression. Interested in how people construe and sustain their subjective reality.
📢Studienteilnehmende gesucht📢
Meine neue Doktorandin Fiona Friedrich testet eine neue experimentelle Aufgabe zu sozialem Lernen in der psychotherapeutischen Beziehung. Online bearbeitbar, kein Vorwissen nötig. Hier geht's zur Studie 👇
www.soscisurvey.de/TATRUSTFF/
Meine neue Doktorandin Fiona Friedrich testet eine neue experimentelle Aufgabe zu sozialem Lernen in der psychotherapeutischen Beziehung. Online bearbeitbar, kein Vorwissen nötig. Hier geht's zur Studie 👇
www.soscisurvey.de/TATRUSTFF/
Fragebogen | Seite 1
www.soscisurvey.de
September 18, 2026 at 6:49 AM
📢Studienteilnehmende gesucht📢
Meine neue Doktorandin Fiona Friedrich testet eine neue experimentelle Aufgabe zu sozialem Lernen in der psychotherapeutischen Beziehung. Online bearbeitbar, kein Vorwissen nötig. Hier geht's zur Studie 👇
www.soscisurvey.de/TATRUSTFF/
Meine neue Doktorandin Fiona Friedrich testet eine neue experimentelle Aufgabe zu sozialem Lernen in der psychotherapeutischen Beziehung. Online bearbeitbar, kein Vorwissen nötig. Hier geht's zur Studie 👇
www.soscisurvey.de/TATRUSTFF/
New article with @a-seewald.bsky.social: We show that patients' responses to normal diagnostic test results critically depend on the doctor's behaviour. If they are warm and competent, patients can take in such information much better and have less desire to consult other doctors or have more tests.
How a physician communicates normal tests results may determine how the information lands with a patient.
🔗 - doi.org/10.1370/afm....
Communicating test results that are normal & reveal no abnormalities isn’t always enough to ease a patient’s worries or deter them from seeking a second opinion.
🔗 - doi.org/10.1370/afm....
Communicating test results that are normal & reveal no abnormalities isn’t always enough to ease a patient’s worries or deter them from seeking a second opinion.
September 10, 2026 at 6:28 AM
New article with @a-seewald.bsky.social: We show that patients' responses to normal diagnostic test results critically depend on the doctor's behaviour. If they are warm and competent, patients can take in such information much better and have less desire to consult other doctors or have more tests.
Was ich nicht mehr hören kann: Wenn davon gesprochen wird, was "die Leute" angeblich wollen. Abgesehen davon, dass ich es ziemlich anmaßend finde, ohne Mandat für die vermeintlichen Wünsche anderer zu sprechen, ist diese Floskel in einer hoch individualisierten Gesellschaft analytisch wertlos.
September 9, 2026 at 3:44 PM
Was ich nicht mehr hören kann: Wenn davon gesprochen wird, was "die Leute" angeblich wollen. Abgesehen davon, dass ich es ziemlich anmaßend finde, ohne Mandat für die vermeintlichen Wünsche anderer zu sprechen, ist diese Floskel in einer hoch individualisierten Gesellschaft analytisch wertlos.
Reposted by Tobias Kube
Great work from our affiliated project AF05 led by @tobikube.bsky.social! 🌟
Positive framing (the likelihood of NOT HAVING a disease) reduces perceived risk & emotional concern to normal diagnostic test results. It also reduces intentions for follow-up consultations & further tests.
Positive framing (the likelihood of NOT HAVING a disease) reduces perceived risk & emotional concern to normal diagnostic test results. It also reduces intentions for follow-up consultations & further tests.
September 2, 2026 at 11:47 AM
Great work from our affiliated project AF05 led by @tobikube.bsky.social! 🌟
Positive framing (the likelihood of NOT HAVING a disease) reduces perceived risk & emotional concern to normal diagnostic test results. It also reduces intentions for follow-up consultations & further tests.
Positive framing (the likelihood of NOT HAVING a disease) reduces perceived risk & emotional concern to normal diagnostic test results. It also reduces intentions for follow-up consultations & further tests.
Reposted by Tobias Kube
🔥🔥New paper alert!
Super excited to share our paper, out today in @nathumbehav.nature.com, led by the wonderful Dr. Nofar Mizrachi!
nature.com/articles/s41...
To me, this finding fundamentally changes how we should think about the relationship between cognition and immune regulation:
Super excited to share our paper, out today in @nathumbehav.nature.com, led by the wonderful Dr. Nofar Mizrachi!
nature.com/articles/s41...
To me, this finding fundamentally changes how we should think about the relationship between cognition and immune regulation:
Voluntary attention regulates acute immune responses in humans - Nature Human Behaviour
Mizrachi et al. show that directing attention to bodily sensations, rather than away, promotes more regulated acute inflammatory responses in healthy volunteers, revealing sensory and vagal pathways l...
nature.com
August 17, 2026 at 9:51 AM
🔥🔥New paper alert!
Super excited to share our paper, out today in @nathumbehav.nature.com, led by the wonderful Dr. Nofar Mizrachi!
nature.com/articles/s41...
To me, this finding fundamentally changes how we should think about the relationship between cognition and immune regulation:
Super excited to share our paper, out today in @nathumbehav.nature.com, led by the wonderful Dr. Nofar Mizrachi!
nature.com/articles/s41...
To me, this finding fundamentally changes how we should think about the relationship between cognition and immune regulation:
In this new study published open access in Translational Medicine @springernature.com we show that in a sample of clinically depressed people, higher symptom burden is related to reduced learning from positive prediction errors and aberrant neural response to neg PEs.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Aberrant insula activity to negative and reduced learning from positive feedback underlie maladaptive self-beliefs in depression - Translational Psychiatry
Translational Psychiatry - Aberrant insula activity to negative and reduced learning from positive feedback underlie maladaptive self-beliefs in depression
www.nature.com
August 17, 2026 at 8:39 AM
In this new study published open access in Translational Medicine @springernature.com we show that in a sample of clinically depressed people, higher symptom burden is related to reduced learning from positive prediction errors and aberrant neural response to neg PEs.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Is 10% the same as 1 in 10? It is not, our results suggest, at least not in terms of how people respond to such likelihoods when it comes to medical diagnostic information. Results speak to the importance of thoughtful likelihood framing in clinical practice. www.sciencedirect.com/science/arti....
When ‘unlikely’ is not the same as ‘likely not’: Effects of likelihood framing and numerical format on patients’ responses to normal diagnostic test results
Communicating the results of diagnostic testing is a central task in clinical practice. Even when results are normal, patients may remain concerned, p…
www.sciencedirect.com
August 17, 2026 at 6:40 AM
Is 10% the same as 1 in 10? It is not, our results suggest, at least not in terms of how people respond to such likelihoods when it comes to medical diagnostic information. Results speak to the importance of thoughtful likelihood framing in clinical practice. www.sciencedirect.com/science/arti....
Reposted by Tobias Kube
“People interpret numbers in very different ways,” says psychologist @tobikube.bsky.social in the latest episode of our CRC podcast 🎙️👨⚕️
In medicine, it is particularly important to communicate quantities and figures sensitively.
Listen now: open.spotify.com/episode/6mC0...
In medicine, it is particularly important to communicate quantities and figures sensitively.
Listen now: open.spotify.com/episode/6mC0...
July 17, 2026 at 2:36 PM
“People interpret numbers in very different ways,” says psychologist @tobikube.bsky.social in the latest episode of our CRC podcast 🎙️👨⚕️
In medicine, it is particularly important to communicate quantities and figures sensitively.
Listen now: open.spotify.com/episode/6mC0...
In medicine, it is particularly important to communicate quantities and figures sensitively.
Listen now: open.spotify.com/episode/6mC0...
So ist es. www.zeit.de/2026/31/gesu...
Gesundheitsreform: Klares Signal: Stellt euch nicht so an!
Die Gesundheitsreform könnte ausgerechnet die Psychotherapeuten am härtesten treffen. Hält die Bundesregierung ihre Bürger für verweichlicht? Das wäre ein Fehler.
www.zeit.de
July 15, 2026 at 5:34 PM
So ist es. www.zeit.de/2026/31/gesu...
Reposted by Tobias Kube
New research Article in the journal by Annalina V. Mayer and colleagues: www.nature.com/articles/s44...
Causal attributions shape the formation of novel ability self-beliefs - Communications Psychology
Using computational modeling, this study shows that causal attributions are associated with how people form ability beliefs. Lower self-esteem and higher depressive symptoms were linked to stronger ne...
www.nature.com
June 11, 2026 at 8:12 AM
New research Article in the journal by Annalina V. Mayer and colleagues: www.nature.com/articles/s44...
🎉🥳📢: New article published in @commspsychol.nature.com! We show that causal attributions regarding success vs. failure modulate the formation and update of self-beliefs and these effects are moderated by self-esteem, pointing to the clinical relevance of the findings.
www.nature.com/articles/s44...
www.nature.com/articles/s44...
www.nature.com
June 15, 2026 at 5:49 AM
🎉🥳📢: New article published in @commspsychol.nature.com! We show that causal attributions regarding success vs. failure modulate the formation and update of self-beliefs and these effects are moderated by self-esteem, pointing to the clinical relevance of the findings.
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Guter Artikel über die Anreizstrukturen, die zu ineffizienter, teurer und nicht besonders guter stationärer psychiatrischer Versorgung führen. Was es bräuchte: mehr ambulante Versorgung, mehr stationsäquivalente Behandlung und flexiblere Abrechnungsmöglichkeiten stationär www.zeit.de/gesundheit/2...
Psychiatrische Kliniken: Drei Wochen auf Station, dann alleine nach Hause
Die deutsche Psychiatrie ist teuer, aber nur mittelgut. Die Regierung will nichts ändern. Das zeigt ein Papier, das der ZEIT vorliegt. Experten wüssten, was zu tun wäre.
www.zeit.de
June 5, 2026 at 12:48 PM
Guter Artikel über die Anreizstrukturen, die zu ineffizienter, teurer und nicht besonders guter stationärer psychiatrischer Versorgung führen. Was es bräuchte: mehr ambulante Versorgung, mehr stationsäquivalente Behandlung und flexiblere Abrechnungsmöglichkeiten stationär www.zeit.de/gesundheit/2...
Für unser Team in Frankfurt suchen wir eine:n Postdoc und Psychotherapeut:in (Fachkunde VT). Stellenbeginn zum 1.10.26 bzw. nach Absprache auch früher oder später. Konzipiert als 80% Stelle, aber 100% wären nach Absprache auch möglich. Jetzt bewerben bis 5.5.26, mehr Details siehe 👇
Wissenschaft & Psychotherapie verbinden? In unserer Psychotherapie-Ambulanz an der Goethe-Universität Frankfurt ist das im Rahmen einer Clinician Scientist Postdoc-Stelle (VT Erw., E14, 80%, befristet zunächst für 3 Jahre) möglich. Bewerbungsfrist: 05.05.2026. Mehr 👉: www.psychjob.eu/de/job/wisse...
April 27, 2026 at 5:59 AM
Für unser Team in Frankfurt suchen wir eine:n Postdoc und Psychotherapeut:in (Fachkunde VT). Stellenbeginn zum 1.10.26 bzw. nach Absprache auch früher oder später. Konzipiert als 80% Stelle, aber 100% wären nach Absprache auch möglich. Jetzt bewerben bis 5.5.26, mehr Details siehe 👇
Toller Artikel @zeit.de über Placebo-Effekte @sfb-trr-289.bsky.social. Toll auf den Punkt gebracht, dass der Placebo-Effekt ein klinisch extremlich nützlicher Mechanismus ist, der von Medizin und Pharma als Freund, nicht als Feind, betrachtet werden sollte. www.zeit.de/gesundheit/2...
Placebo-Forschung: Placebos sind der Schlüssel zu einer menschlichen Medizin
Wir haben eine Apotheke in uns, die wir kostenlos nutzen können. Der Placebo-Effekt ist so stark, dass wir eigentlich das gesamte Gesundheitswesen umkrempeln müssten.
www.zeit.de
April 12, 2026 at 5:48 PM
Toller Artikel @zeit.de über Placebo-Effekte @sfb-trr-289.bsky.social. Toll auf den Punkt gebracht, dass der Placebo-Effekt ein klinisch extremlich nützlicher Mechanismus ist, der von Medizin und Pharma als Freund, nicht als Feind, betrachtet werden sollte. www.zeit.de/gesundheit/2...
Wissenschaft & Psychotherapie verbinden? In unserer Psychotherapie-Ambulanz an der Goethe-Universität Frankfurt ist das im Rahmen einer Clinician Scientist Postdoc-Stelle (VT Erw., E14, 80%, befristet zunächst für 3 Jahre) möglich. Bewerbungsfrist: 05.05.2026. Mehr 👉: www.psychjob.eu/de/job/wisse...
April 8, 2026 at 7:20 AM
Wissenschaft & Psychotherapie verbinden? In unserer Psychotherapie-Ambulanz an der Goethe-Universität Frankfurt ist das im Rahmen einer Clinician Scientist Postdoc-Stelle (VT Erw., E14, 80%, befristet zunächst für 3 Jahre) möglich. Bewerbungsfrist: 05.05.2026. Mehr 👉: www.psychjob.eu/de/job/wisse...
🎉🥳 New article by my PhD student Alexandra Spaeth: We investigated pupillary responses to novel positive vs. negative information on interpersonal scenarios in people with major depression vs. healthy control participants. Published open access in BRAT 👇 www.sciencedirect.com/science/arti...
No distorted prediction error processing in depression? Pupillary responses to expected vs. unexpected emotional information in clinically depressed and healthy individuals
Depression has been associated with a reduced ability to update negative beliefs, possibly driven by difficulties integrating new positive information…
www.sciencedirect.com
February 13, 2026 at 7:06 AM
🎉🥳 New article by my PhD student Alexandra Spaeth: We investigated pupillary responses to novel positive vs. negative information on interpersonal scenarios in people with major depression vs. healthy control participants. Published open access in BRAT 👇 www.sciencedirect.com/science/arti...
Reposted by Tobias Kube
🤕 Many patients find it difficult to interpret figures relating to frequencies and probabilities in medicine.
There is therefore a risk that careless wording could cause confusion or even anxiety! 😰
There is therefore a risk that careless wording could cause confusion or even anxiety! 😰
February 2, 2026 at 9:26 AM
🤕 Many patients find it difficult to interpret figures relating to frequencies and probabilities in medicine.
There is therefore a risk that careless wording could cause confusion or even anxiety! 😰
There is therefore a risk that careless wording could cause confusion or even anxiety! 😰
Reposted by Tobias Kube
🚨🚨Abstract submission deadline extended!🚨🚨
⏰ New submission deadline is 16th of February 2026
📢 <1 month left to submit abstracts for the 𝟮𝟬𝟮𝟲 𝗔𝘂𝘁𝗼𝗯𝗶𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰𝗮𝗹 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 & 𝗣𝘀𝘆𝗰𝗵𝗼𝗽𝗮𝘁𝗵𝗼𝗹𝗼𝗴𝘆 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 hashtag#APP2026, 23rd-24th June in Plymouth, UK 🌊!
📌Visit: www.plymouth.ac.uk/whats-on/aut...
⏰ New submission deadline is 16th of February 2026
📢 <1 month left to submit abstracts for the 𝟮𝟬𝟮𝟲 𝗔𝘂𝘁𝗼𝗯𝗶𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰𝗮𝗹 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 & 𝗣𝘀𝘆𝗰𝗵𝗼𝗽𝗮𝘁𝗵𝗼𝗹𝗼𝗴𝘆 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 hashtag#APP2026, 23rd-24th June in Plymouth, UK 🌊!
📌Visit: www.plymouth.ac.uk/whats-on/aut...
January 18, 2026 at 6:36 PM
🚨🚨Abstract submission deadline extended!🚨🚨
⏰ New submission deadline is 16th of February 2026
📢 <1 month left to submit abstracts for the 𝟮𝟬𝟮𝟲 𝗔𝘂𝘁𝗼𝗯𝗶𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰𝗮𝗹 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 & 𝗣𝘀𝘆𝗰𝗵𝗼𝗽𝗮𝘁𝗵𝗼𝗹𝗼𝗴𝘆 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 hashtag#APP2026, 23rd-24th June in Plymouth, UK 🌊!
📌Visit: www.plymouth.ac.uk/whats-on/aut...
⏰ New submission deadline is 16th of February 2026
📢 <1 month left to submit abstracts for the 𝟮𝟬𝟮𝟲 𝗔𝘂𝘁𝗼𝗯𝗶𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰𝗮𝗹 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 & 𝗣𝘀𝘆𝗰𝗵𝗼𝗽𝗮𝘁𝗵𝗼𝗹𝗼𝗴𝘆 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 hashtag#APP2026, 23rd-24th June in Plymouth, UK 🌊!
📌Visit: www.plymouth.ac.uk/whats-on/aut...
Schöner Beitrag über den JAMA Letter von @rief01.bsky.social und mir. flugundzeit.blog/drei-von-hun...
Die Macht der Zahlen: 3% vs. drei von Hundert verstehen
Entdecken Sie, wie Sprache und Zahlen unsere Wahrnehmung von Heilung und Risiken beeinflussen – eine spannende Analyse von Kube und Rief.
flugundzeit.blog
January 30, 2026 at 4:51 PM
Schöner Beitrag über den JAMA Letter von @rief01.bsky.social und mir. flugundzeit.blog/drei-von-hun...
🎉 New article on the effects of likelihood framing on nocebo side effects. Finding: Framing influenced side effect expectations, but not side effect experiences - presumably due to insufficient nocebo effects induced by the experimental model. OA👇 bpspsychub.onlinelibrary.wiley.com/doi/10.1111/....
<em>British Journal of Health Psychology</em> | Wiley Online Library
Objectives This research examined whether different framings of the likelihood of side effects influence their occurrence in response to a placebo analgesic. Design Three independent experimental ...
bpspsychub.onlinelibrary.wiley.com
January 28, 2026 at 7:52 AM
🎉 New article on the effects of likelihood framing on nocebo side effects. Finding: Framing influenced side effect expectations, but not side effect experiences - presumably due to insufficient nocebo effects induced by the experimental model. OA👇 bpspsychub.onlinelibrary.wiley.com/doi/10.1111/....
🎉 Happy to share a Letter with @rief01.bsky.social in @jama.com: We argue that clinicians should be aware of framing effects when communicating likelihoods. Eg, patients perceive "1 in 10 have side effects" as more concerning than "9 in 10 do not have side effects". jamanetwork.com/journals/jam...
Communicating Medical Numbers
To the Editor Dr Zikmund-Fisher and colleagues1 highlight several important caveats regarding the presentation of numbers in medical communication and provide thoughtful suggestions for clinicians on ...
jamanetwork.com
January 27, 2026 at 9:07 AM
🎉 Happy to share a Letter with @rief01.bsky.social in @jama.com: We argue that clinicians should be aware of framing effects when communicating likelihoods. Eg, patients perceive "1 in 10 have side effects" as more concerning than "9 in 10 do not have side effects". jamanetwork.com/journals/jam...
🧠💡Reden ist Silber, Ausprobieren ist Gold!
Am 20.06. organisieren wir in Frankfurt ein Praxissymposium zum Thema Verhaltensexperimente. Programm: Vorträge & Workshops mit führenden Expert:innen, u.a. @michaelwitthoeft.bsky.social. Jetzt informieren & anmelden! www.uni-frankfurt.de/110078906/Pr...
Am 20.06. organisieren wir in Frankfurt ein Praxissymposium zum Thema Verhaltensexperimente. Programm: Vorträge & Workshops mit führenden Expert:innen, u.a. @michaelwitthoeft.bsky.social. Jetzt informieren & anmelden! www.uni-frankfurt.de/110078906/Pr...
Goethe-Universität — Praxissymposium
Die Goethe-Universität ist eine forschungsstarke Hochschule in der europäischen Finanzmetropole Frankfurt. Lebendig, urban und weltoffen besitzt sie als Stiftungsuniversität ein einzigartiges Maß an E...
www.uni-frankfurt.de
January 23, 2026 at 7:55 AM
🧠💡Reden ist Silber, Ausprobieren ist Gold!
Am 20.06. organisieren wir in Frankfurt ein Praxissymposium zum Thema Verhaltensexperimente. Programm: Vorträge & Workshops mit führenden Expert:innen, u.a. @michaelwitthoeft.bsky.social. Jetzt informieren & anmelden! www.uni-frankfurt.de/110078906/Pr...
Am 20.06. organisieren wir in Frankfurt ein Praxissymposium zum Thema Verhaltensexperimente. Programm: Vorträge & Workshops mit führenden Expert:innen, u.a. @michaelwitthoeft.bsky.social. Jetzt informieren & anmelden! www.uni-frankfurt.de/110078906/Pr...
Happy to share the last contribution of our special issue on belief updating in Behaviour Research and Therapy: Jonas'es and my editorial, providing a brief narrative review of the topic and an introduction to the articles of the special issue. authors.elsevier.com/a/1m7Eo1KMdl...
authors.elsevier.com
November 21, 2025 at 6:19 AM
Happy to share the last contribution of our special issue on belief updating in Behaviour Research and Therapy: Jonas'es and my editorial, providing a brief narrative review of the topic and an introduction to the articles of the special issue. authors.elsevier.com/a/1m7Eo1KMdl...
Reposted by Tobias Kube
✨Wunderbare Neuigkeiten: Die Deutsche Forschungsgemeinschaft fördert unser neues Netzwerk SNEPP – das Scientific Network for Experimental Psychopathology and Psychotherapy!
www.uni-goettingen.de/de/3240.html...
www.uni-goettingen.de/de/3240.html...
Presseinformationen - Georg-August-Universität Göttingen
Webseiten der Georg-August-Universität Göttingen
www.uni-goettingen.de
November 17, 2025 at 3:14 PM
✨Wunderbare Neuigkeiten: Die Deutsche Forschungsgemeinschaft fördert unser neues Netzwerk SNEPP – das Scientific Network for Experimental Psychopathology and Psychotherapy!
www.uni-goettingen.de/de/3240.html...
www.uni-goettingen.de/de/3240.html...
New paper in CPS 🎉: We developed and validated a novel trial-by-trial belief update task, which allowed us to examine the association with depression quite precisely: dep symptoms were related to a slower update of established negative beliefs following pos info. journals.sagepub.com/doi/10.1177/...
Intraindividual Trajectories of Belief Updating in Relation to Depressive Symptoms: Reduced Integration of Positive Performance Feedback - Sebastian Meyerhöfer, Charlotte Ottenstein, Lukas Kirchner, L...
Previous research suggests that depression is related to difficulties with revising established negative expectations. However, it is not yet clear how precisel...
journals.sagepub.com
November 14, 2025 at 7:10 AM
New paper in CPS 🎉: We developed and validated a novel trial-by-trial belief update task, which allowed us to examine the association with depression quite precisely: dep symptoms were related to a slower update of established negative beliefs following pos info. journals.sagepub.com/doi/10.1177/...