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Research at UHN
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Research news from Canada's largest research hospital.
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Driving Discovery. Delivering Impact.🎯

A story of science that’s bold, transformative, and collaborative.

This #WorldScienceDay, explore our annual research report and discover how @uhn.ca is building #AHealthierWorld.

➡️: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
1/ A study from @uhn.ca shows that hospital-affiliated warming centres could help reduce emergency department overcrowding by providing a safe discharge option for people experiencing homelessness in winter—reinforcing the need for supportive housing.

🔗: www.uhnresearch.ca/news/10-02-2...
October 2, 2026 at 6:12 PM
Reposted by Research at UHN
📢 New publication alert!

A recent study led by Dr. Jarryll Uy, a Postdoctoral Researcher, has uncovered an unexpected role for SCN2A, one of the risk genes associated with autism, revealing that it begins shaping brain development much earlier than previously understood >> bit.ly/4hz6Xor (1/2)
October 2, 2026 at 4:46 PM
#GairdnerScienceWeek is back October 19 to 23. Join world-leading scientists for free public events celebrating cutting-edge research, global health innovation, and the brilliant 2026 Gairdner Awards laureates.

🔗 Register today: www.gairdner.org/event-item/g...

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@gairdnerawards.bsky.social
October 1, 2026 at 3:12 PM
Read about the latest findings from Canada’s largest #research hospital in @uhn.ca ’s Research Spotlight newsletter:

▶️ New treatment for bipolar depression
▶️ #AI tool for cancer treatment
▶️ Retaining registered practical nurses
+ More

🔗: www.uhnresearch.ca/nrx_newslett...
September 30, 2026 at 6:37 PM
🚨Out today in @natimmunol.nature.com, a study from @pmresearch-uhn.bsky.social’s Dr. Anastasia Tikhonova identifies distinctive early changes in the bone marrow environment in people with age-related blood #StemCell mutations, before blood cancer develops.

⬇️
In people with age-related blood stem cell mutations, our study found early pre-fibrosis and inflammatory regions in the bone marrow, that may set the stage for blood cancer development.

The @natimmunol.nature.com study was led by Dr. Anastasia Tikhonova:
www.nature.com/articles/s41...
September 30, 2026 at 1:48 PM
Out today in @natbiotech.nature.com, a study from Dr. Bowen Li (@pmresearch-uhn.bsky.social) shows a new strategy for improving the non-viral delivery of large mRNA cargo for gene editing—an approach with the potential to expand the reach of gene editing therapies.

🔗: www.nature.com/articles/s41...
September 28, 2026 at 4:35 PM
Congratulations to Dr. Tak Mak, Senior Scientist at @pmresearch-uhn.bsky.social, on receiving the German Society of Immunology's German Immunology Prize. 🎉

As the Society's highest scientific honour, the award recognizes outstanding contributions to immunology.

🔗: idw-online.de/en/news877636
Die Deutsche Gesellschaft für Immunologie e.V. (DGfI) vergibt ihre höchste wissenschaftliche Auszeichnung dieses Jahr an Prof. Mark Davis und Prof. Tak Mak. Die beiden Forscher haben die moderne Immunologie grundlegend geprägt. Siehe dgfi.org/mark-davis-u...
September 25, 2026 at 5:19 PM
Postdoctoral researchers play an important role in advancing discovery and innovation at @uhn.ca.

During #PostdocAppreciationWeek, we're highlighting members of UHN's postdoctoral community and the work they're leading across a range of research areas. 🧵⬇️
September 21, 2026 at 3:10 PM
New research from @pmresearch-uhn.bsky.social shows how chemotherapy can cause long-term damage to bone & and blood-forming cells in the bone marrow by triggering inflammation—offering insight into why many cancer survivors face lasting health challenges.

🔗: www.uhnresearch.ca/news/9-18-20...
September 18, 2026 at 3:32 PM
Reposted by Research at UHN
Congratulations to Dr. Long Nguyen on being named Canada's Top 40 Under 40 by @financialpost.com for leading a research program uncovering how cancer cells evolve, adapt, and develop resistance to treatment, to improve patient outcomes.

@uhnresearch.ca @uhn.ca
September 17, 2026 at 1:52 PM
Can a low-cost depth camera make balance rehabilitation more accessible?

Researchers at @kiteuhn.bsky.social found a depth camera performed similarly to traditional force plates used in balance training, suggesting a more accessible rehabilitation approach.

🔗: www.uhnresearch.ca/news/9-16-20...
September 17, 2026 at 2:51 PM
#NewPublication🚨

Researchers at @pmresearch-uhn.bsky.social have developed a new #AI tool that can identify rare immune cells with the ability to recognize and respond to #cancer.

🔗 Read more: www.uhnresearch.ca/news/9-16-20...
Finding immune cells that naturally recognize cancer has been a barrier to developing T cell-based therapies. Our study used AI to decode what makes γδ T cells respond to tumour cells, unlocking new therapeutic potentials.
@nature.com : www.nature.com/articles/s41...
@uhnresearch.ca @uhn.ca
September 16, 2026 at 4:31 PM
Reposted by Research at UHN
The Princess Margaret Living Biobank is celebrating 10 years of advancing cancer research through patient-derived models. Join researchers, collaborators, and the UHN community on October 8 for food, refreshments, remarks, and a celebration of impact, discovery, and innovation.

@uhnresearch.ca
September 11, 2026 at 5:53 PM
1/ Why does deep brain stimulation (DBS) affect people with #Parkinsons differently?

Researchers at @kbi-uhn.bsky.social found that DBS affects brain-wide networks and that outcomes differ across two common targets. The findings could help personalize care.

🔗: www.uhnresearch.ca/news/9-07-20...
September 10, 2026 at 3:14 PM
Congratulations to @uhn.ca’s Drs. Laura Dawson and Jan Seuntjens, who have been elected to the Royal Society of Canada—Canada’s leading body of scholars, researchers & artists! 🎉

Their transformative work in radiation oncology is shaping the future of health.

🔗 : www.uhnresearch.ca/news/9-09-20...
September 9, 2026 at 4:31 PM
1/ Improving care goes beyond clinical expertise. A @tier-uhn.bsky.social study identified ways continuing professional development programs can improve teaching on topics such as health equity and power dynamics to advance collaboration and patient care.

🔗: www.uhnresearch.ca/news/9-08-20...
September 8, 2026 at 3:07 PM
A new study from @uhn.ca’s Peter Munk Cardiac Centre shows that the protein ERG helps protect blood vessels from changes that drive atherosclerosis—the buildup of plaque in the arteries. Findings could point to future therapeutic strategies to protect arteries.

🔗: www.uhnresearch.ca/news/9-04-20...
September 4, 2026 at 3:13 PM
1/ Four infusions. Two weeks. One important step toward expanding treatment options.

A @uhn.ca-led clinical trial found that ketamine reduced symptoms in adults with treatment-resistant #BipolarDepression and was well tolerated throughout the study.

🔗: www.uhnresearch.ca/news/9-02-20...
September 3, 2026 at 3:50 PM
1/ Researchers at @pmresearch-uhn.bsky.social have developed an RNA-based therapy that can repair disease-causing genetic "stop" signals.

Out today in @science.org, the approach has the potential to treat certain genetic disorders such as cystic fibrosis.

🔗: www.uhnresearch.ca/news/8-27-20...
August 27, 2026 at 6:47 PM
Congratulations to @uhn.ca’s Drs. Niall Ferguson, Jennie Johnstone, Michael Milosevic, & Gang Zheng on being elected as Fellows of the Canadian Academy of Health Sciences.

Their research is improving health outcomes in Canada and beyond.

🔗: www.uhnresearch.ca/news/8-25-20...
August 25, 2026 at 4:06 PM
People with #ALS often face uncertainty about disease progression and care management.

@kiteuhn.bsky.social researchers found that access to personalized information and more patient-centred support may help people make more informed choices about their care.

🔗: www.uhnresearch.ca/news/8-25-20...
August 25, 2026 at 3:13 PM
1/ A new study from @pmresearch-uhn.bsky.social introduces a new #AI model that could make gene editing more effective.

DeepCC9 predicts which CRISPR-Cas9 guide RNAs will perform best while revealing the sequence patterns behind successful gene editing.

🔗: www.uhnresearch.ca/news/8-24-20...
August 24, 2026 at 3:23 PM
Reposted by Research at UHN
Get a behind-the-scenes look as some of this year's summer students @kbi-uhn.bsky.social @dkjei-uhn.bsky.social @schroeder-uhn.bsky.social as they share what it was like working in the lab and reflect on their research experiences this summer >> bit.ly/4gflcOG

@uhn.ca @uhnresearch.ca
August 18, 2026 at 1:26 PM
Reposted by Research at UHN
Ajmera Transplant Centre Research Day 2026 brought our transplant community together to share discoveries, celebrate excellence, and advance the future of transplantation.

Read more: https://ow.ly/Pyc250ZzQ6N

#Transplantation #Research #UHN
August 14, 2026 at 2:02 PM
1/ A new blood test-based method developed by researchers at @pmresearch-uhn.bsky.social could detect and classify metastatic breast cancer without the need for invasive tissue biopsies.

🔗 Read more: www.uhnresearch.ca/news/8-04-20...
August 13, 2026 at 3:54 PM