Paul Carini
@uncultured.carinilab.com
Systems Microbial Ecologist | Microbial Cultivation | F1 & IndyCar fan. Metalhead. Studying microbes in Desert Soil and nearshore Marine Sediments.
Blog: uncultured.carinilab.com
Web: CariniLab.com
Linkedin: https://www.linkedin.com/in/paul-carini/
Blog: uncultured.carinilab.com
Web: CariniLab.com
Linkedin: https://www.linkedin.com/in/paul-carini/
Pinned
These bizarre, much-coveted microbes are revealing the origins of complex life
Researchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way.
www.nature.com
The real story behind the work is @oceancait.bsky.social and the rest of our team who've spent years coaxing our Asgard culture along. They are bizarre, frustrating, and unlike anything I've been a part of. More to share soon. www.nature.com/articles/d41...
Reposted by Paul Carini
Woohoo! We got our @ukri.org BBSRC grant to work on TonB-dependent transport of phospholipids headgroups. We will be hiring a postdoc for a 3-year to start in the new year. See our preprint www.biorxiv.org/content/10.6...
Outer membrane ‘PusCD’ complexes coordinate phospho(inositol)lipid utilisation in plant Bacteroidota
Gram-negative bacteria belonging to the phylum Bacteroidota are prominent and ecologically important members of host-associated microbiomes. A feature of Bacteroidota species is the presence of divers...
www.biorxiv.org
September 17, 2026 at 7:10 PM
Woohoo! We got our @ukri.org BBSRC grant to work on TonB-dependent transport of phospholipids headgroups. We will be hiring a postdoc for a 3-year to start in the new year. See our preprint www.biorxiv.org/content/10.6...
Reposted by Paul Carini
Authors!🚨 While you scramble for scarce $ 🤔
“Springer Nature reports revenue growth of 6.2%..and adjusted operating profit growth of 7.7%. They reported even more stunning submission growth of 30% and published article growth of 13%.”
Publishing in society journals helps YOU not them👇🏻. Pass it on.
“Springer Nature reports revenue growth of 6.2%..and adjusted operating profit growth of 7.7%. They reported even more stunning submission growth of 30% and published article growth of 13%.”
Publishing in society journals helps YOU not them👇🏻. Pass it on.
Man Lying on a Pile of Money
ALT: Man Lying on a Pile of Money
static.klipy.com
September 16, 2026 at 3:05 PM
Authors!🚨 While you scramble for scarce $ 🤔
“Springer Nature reports revenue growth of 6.2%..and adjusted operating profit growth of 7.7%. They reported even more stunning submission growth of 30% and published article growth of 13%.”
Publishing in society journals helps YOU not them👇🏻. Pass it on.
“Springer Nature reports revenue growth of 6.2%..and adjusted operating profit growth of 7.7%. They reported even more stunning submission growth of 30% and published article growth of 13%.”
Publishing in society journals helps YOU not them👇🏻. Pass it on.
The real story behind the work is @oceancait.bsky.social and the rest of our team who've spent years coaxing our Asgard culture along. They are bizarre, frustrating, and unlike anything I've been a part of. More to share soon. www.nature.com/articles/d41...
These bizarre, much-coveted microbes are revealing the origins of complex life
Researchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way.
www.nature.com
September 16, 2026 at 2:04 PM
The real story behind the work is @oceancait.bsky.social and the rest of our team who've spent years coaxing our Asgard culture along. They are bizarre, frustrating, and unlike anything I've been a part of. More to share soon. www.nature.com/articles/d41...
Reposted by Paul Carini
Reposted by Paul Carini
The latest from Think Like a Microbe
thinkmicrobe.substack.com/p/jumping-to...
What should be the standard of evidence for a claim?
Here, 'metabolic cooperation' between auxotrophs and prototrophs
🧪🧫 #philsci
thinkmicrobe.substack.com/p/jumping-to...
What should be the standard of evidence for a claim?
Here, 'metabolic cooperation' between auxotrophs and prototrophs
🧪🧫 #philsci
Jumping to conclusions
I follow Cameron Thrash on social media as he regularly posts links to interesting microbial ecology papers.
thinkmicrobe.substack.com
September 15, 2026 at 2:22 AM
The latest from Think Like a Microbe
thinkmicrobe.substack.com/p/jumping-to...
What should be the standard of evidence for a claim?
Here, 'metabolic cooperation' between auxotrophs and prototrophs
🧪🧫 #philsci
thinkmicrobe.substack.com/p/jumping-to...
What should be the standard of evidence for a claim?
Here, 'metabolic cooperation' between auxotrophs and prototrophs
🧪🧫 #philsci
We don't believe long-time-loving as an extremophilic category is an appropriate way to view energy-starved life. Most data indicates that once energy flux is restored (lab or in situ) these cells resume growth at a more rapid pace, suggesting they are not obligately bound to slow growth
We propose anergiobiosis as an alternative framework. anergiobiosis describes the state of maintaining cellular viability when energy supply falls below thresholds supporting cell division but allows maintenance metabolism. Our concept is mechanistically grounded and testable.
September 14, 2026 at 2:03 PM
We don't believe long-time-loving as an extremophilic category is an appropriate way to view energy-starved life. Most data indicates that once energy flux is restored (lab or in situ) these cells resume growth at a more rapid pace, suggesting they are not obligately bound to slow growth
Good opportunity for a postdoc
My lab is hiring two(!) postdocs interested in (1) building trait prediction models capable of resolving complex microbial traits from genomes and metagenomes, and/or (2) building mathematical models of microbial
community dynamics
www.microbialgamut.com/mGAMUT_postd...
community dynamics
www.microbialgamut.com/mGAMUT_postd...
www.microbialgamut.com
September 10, 2026 at 7:02 PM
Good opportunity for a postdoc
Reposted by Paul Carini
Over the past decade, a toxic fungus that destroys cheese rinds has been popping up in cheese caves throughout New England.
In a new paper from my lab, we tried to better understand this emerging threat to New England's artisan cheese industry. doi.org/10.1128/aem....
In a new paper from my lab, we tried to better understand this emerging threat to New England's artisan cheese industry. doi.org/10.1128/aem....
September 9, 2026 at 12:26 PM
Over the past decade, a toxic fungus that destroys cheese rinds has been popping up in cheese caves throughout New England.
In a new paper from my lab, we tried to better understand this emerging threat to New England's artisan cheese industry. doi.org/10.1128/aem....
In a new paper from my lab, we tried to better understand this emerging threat to New England's artisan cheese industry. doi.org/10.1128/aem....
Zhiwwei gave an excellent talk in our ISME session. They demonstrated inhibitory substances (distinct from ROS) in solid solid media are generated during autoclaving but can be washed out.
Solid media is not inert!
Solid media is not inert!
Overcoming gelling agent-derived inhibitory factors enables the cultivation of fastidious nitrifiers on solid media academic.oup.com/ismecommun/a... #jcampubs
September 8, 2026 at 8:22 PM
Zhiwwei gave an excellent talk in our ISME session. They demonstrated inhibitory substances (distinct from ROS) in solid solid media are generated during autoclaving but can be washed out.
Solid media is not inert!
Solid media is not inert!
We are happy to support an NSF PRFB application that makes use of AI to advance microbial cultivation for biotechnological purposes. Deadline=Sept 29th.
More here: uncultured.carinilab.com/p/were-looki...
More here: uncultured.carinilab.com/p/were-looki...
We're Looking to Sponsor Postdoc Fellows in AI-Driven Microbial Cultivation
NSF Postdoctoral Research Fellowships in Biology
uncultured.carinilab.com
September 8, 2026 at 3:47 PM
We are happy to support an NSF PRFB application that makes use of AI to advance microbial cultivation for biotechnological purposes. Deadline=Sept 29th.
More here: uncultured.carinilab.com/p/were-looki...
More here: uncultured.carinilab.com/p/were-looki...
Reposted by Paul Carini
DEEP SEA MICROBIO is here.
Creatures in inky trenches.
Exploring the sea floor.
Mud medicine.
Tube worms.
The legend, Dr. @pgirguis.bsky.social, explains it all.
www.alieward.com/ologies/deep...
Creatures in inky trenches.
Exploring the sea floor.
Mud medicine.
Tube worms.
The legend, Dr. @pgirguis.bsky.social, explains it all.
www.alieward.com/ologies/deep...
Deep Sea Microbiology (UNSEEN OCEAN CRITTERS) with Dr. Peter Girguis — alie ward
Creatures in inky trenches. Exploring the sea floor. Mud medicine. Tube worms. Harvard professor and Deep Sea Microbiology legend Dr. Peter Girguis tells tales of ocean expeditions and answers questio...
www.alieward.com
September 3, 2026 at 5:28 PM
DEEP SEA MICROBIO is here.
Creatures in inky trenches.
Exploring the sea floor.
Mud medicine.
Tube worms.
The legend, Dr. @pgirguis.bsky.social, explains it all.
www.alieward.com/ologies/deep...
Creatures in inky trenches.
Exploring the sea floor.
Mud medicine.
Tube worms.
The legend, Dr. @pgirguis.bsky.social, explains it all.
www.alieward.com/ologies/deep...
I still feel a wave of relief when someone says they read our papers and enjoy them.
August 26, 2026 at 5:21 PM
I still feel a wave of relief when someone says they read our papers and enjoy them.
Reposted by Paul Carini
Join the lab of my wife and do some awesome organic chemistry with important medical implications under her new (second) NIH MIRA grant! Living in Bozeman as a bonus. (www.neufeldt-chemistry.com)
The Neufeldt lab is looking to hire a postdoc for an experimental position (organic/organometallic chemistry): jobs.montana.edu/postings/52714
Postdoctoral Research Associate
The Neufeldt Lab is looking for a motivated postdoc to complete a federally funded chemistry research project.
jobs.montana.edu
August 26, 2026 at 1:40 PM
Join the lab of my wife and do some awesome organic chemistry with important medical implications under her new (second) NIH MIRA grant! Living in Bozeman as a bonus. (www.neufeldt-chemistry.com)
Reposted by Paul Carini
The new NSF BIO funding opportunity (solicitation) is out, which replaces the DEB, IOS, and MCB solicitations. The BIO Core accepts proposals that cover the scientific topics associated with the legacy programs historically supported by BIO. BIO Core - NSF 26-517.
www.nsf.gov/funding/oppo...
www.nsf.gov/funding/oppo...
Core Research in Biological Sciences (BIO Core)
www.nsf.gov
August 17, 2026 at 5:17 PM
The new NSF BIO funding opportunity (solicitation) is out, which replaces the DEB, IOS, and MCB solicitations. The BIO Core accepts proposals that cover the scientific topics associated with the legacy programs historically supported by BIO. BIO Core - NSF 26-517.
www.nsf.gov/funding/oppo...
www.nsf.gov/funding/oppo...
Reposted by Paul Carini
Reposted by Paul Carini
Excited to share that I've been awarded a 5-year NIH MIRA (R35) from the National Institute of General Medical Sciences!
The lab is growing! We're recruiting postdocs and research techs interested in microbial ecology, quantitative microscopy, microfluidics, and molecular biology.
Please share!
The lab is growing! We're recruiting postdocs and research techs interested in microbial ecology, quantitative microscopy, microfluidics, and molecular biology.
Please share!
July 12, 2026 at 6:09 PM
Excited to share that I've been awarded a 5-year NIH MIRA (R35) from the National Institute of General Medical Sciences!
The lab is growing! We're recruiting postdocs and research techs interested in microbial ecology, quantitative microscopy, microfluidics, and molecular biology.
Please share!
The lab is growing! We're recruiting postdocs and research techs interested in microbial ecology, quantitative microscopy, microfluidics, and molecular biology.
Please share!
Reposted by Paul Carini
Postdocs and early career folks - this is a truly wonderful opportunity to spend time in Berlin, gain time to think, and expand your network! call.wiko-berlin.de/procedure/65...
Wiko Application Platform
call.wiko-berlin.de
July 9, 2026 at 7:41 AM
Postdocs and early career folks - this is a truly wonderful opportunity to spend time in Berlin, gain time to think, and expand your network! call.wiko-berlin.de/procedure/65...
Had an awesome time at Hayward field watching some jaw-dropping *amazing* athletes do their thing at the Pre Classic this weekend!
July 6, 2026 at 11:34 PM
Had an awesome time at Hayward field watching some jaw-dropping *amazing* athletes do their thing at the Pre Classic this weekend!
Another great read on Think Like a Microbe on Dormancy in microbes.
Just up on Think Like a Microbe -- slacker culture in microbes: an under-appreciated life style
🧪🧫 #philsci
open.substack.com/pub/thinkmic...
🧪🧫 #philsci
open.substack.com/pub/thinkmic...
On microbial dormancy and resuscitation
~25% of world's human population contain latent Mycobacterium tuberculosis cells in lung granulomas
open.substack.com
June 12, 2026 at 6:04 PM
Another great read on Think Like a Microbe on Dormancy in microbes.
Reposted by Paul Carini
Just up on Think Like a Microbe -- slacker culture in microbes: an under-appreciated life style
🧪🧫 #philsci
open.substack.com/pub/thinkmic...
🧪🧫 #philsci
open.substack.com/pub/thinkmic...
On microbial dormancy and resuscitation
~25% of world's human population contain latent Mycobacterium tuberculosis cells in lung granulomas
open.substack.com
June 12, 2026 at 4:02 PM
Just up on Think Like a Microbe -- slacker culture in microbes: an under-appreciated life style
🧪🧫 #philsci
open.substack.com/pub/thinkmic...
🧪🧫 #philsci
open.substack.com/pub/thinkmic...
I am so mad at AI for comandeering the em dash. I loved that thing! Now I am finding myself trying to find other ways to say the same thing when I used to use an em dash. RIP, em.
June 9, 2026 at 9:43 PM
I am so mad at AI for comandeering the em dash. I loved that thing! Now I am finding myself trying to find other ways to say the same thing when I used to use an em dash. RIP, em.
Not a teacher, an academic advisor. After flunking (with a 0.0 GPA) my second straight semester as a freshman in college, I was told "you won't be admitted again unless you can prove you can do college level work."
Get bent, Joe.
Get bent, Joe.
My high school guidance councilor told me that I wasn't college material and not to bother
I believe she's dead now.
I believe she's dead now.
June 1, 2026 at 7:26 PM
Not a teacher, an academic advisor. After flunking (with a 0.0 GPA) my second straight semester as a freshman in college, I was told "you won't be admitted again unless you can prove you can do college level work."
Get bent, Joe.
Get bent, Joe.