Zach Ladwig
@zachladwig.bsky.social
Neuroscience PhD at Northwestern
Pinned
Zach Ladwig
@zachladwig.bsky.social
· May 18
(1/5) Our paper is out now in Neuron!
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
Reposted by Zach Ladwig
1/ [PREPRINT] How is the lateral PFC organized to support cognition? Using precision fMRI, we show adjacent PFC regions support opposing functions, predicted by embedding in distinct networks across 3 cohorts (N=37). This could inform TMS treatment targets. www.biorxiv.org/content/10.6...
www.biorxiv.org
September 7, 2026 at 10:05 PM
1/ [PREPRINT] How is the lateral PFC organized to support cognition? Using precision fMRI, we show adjacent PFC regions support opposing functions, predicted by embedding in distinct networks across 3 cohorts (N=37). This could inform TMS treatment targets. www.biorxiv.org/content/10.6...
Reposted by Zach Ladwig
📣 New preprint: Multiple Nested Distributed Language Networks in the Human Brain. 📣
Brain regions specialized for language have been extensively described. But are they organized into one network, or multiple? Our new preprint provides evidence for the latter:
www.biorxiv.org/content/10.6...
Brain regions specialized for language have been extensively described. But are they organized into one network, or multiple? Our new preprint provides evidence for the latter:
www.biorxiv.org/content/10.6...
Multiple Nested Distributed Language Networks in the Human Brain
Brain regions specialized for language have been extensively described, yet their arrangement into one or multiple networks remains debated. Using precision functional mapping across three independent...
www.biorxiv.org
August 8, 2026 at 7:57 PM
📣 New preprint: Multiple Nested Distributed Language Networks in the Human Brain. 📣
Brain regions specialized for language have been extensively described. But are they organized into one network, or multiple? Our new preprint provides evidence for the latter:
www.biorxiv.org/content/10.6...
Brain regions specialized for language have been extensively described. But are they organized into one network, or multiple? Our new preprint provides evidence for the latter:
www.biorxiv.org/content/10.6...
Reposted by Zach Ladwig
A special highlight of our work on precision fMRI of the prefrontal cortex
Out of the 30 million MRIs performed in the United States every year, data shows about 22% of those are on the brain. Now, researchers at the University of Illinois are mapping out ways to see the results at a more detailed level.
U of I researchers use precision fMRI to map prefrontal cortex
CHAMPAIGN-URBANA, Ill. (WCIA) — Out of the 30 million MRIs performed in the United States every year, data shows about 22% of those are on the brain. Now, researchers at the University of Ill…
www.wcia.com
July 23, 2026 at 12:09 PM
A special highlight of our work on precision fMRI of the prefrontal cortex
Reposted by Zach Ladwig
Happy to share that our paper on objective quality assessment for "precision" fMRI is now out in @cp-neuron.bsky.social
A recap of what it does, what's new since the preprint, and code you can run on your own data.
cell.com/neuron/fullt...
A recap of what it does, what's new since the preprint, and code you can run on your own data.
cell.com/neuron/fullt...
June 22, 2026 at 5:22 PM
Happy to share that our paper on objective quality assessment for "precision" fMRI is now out in @cp-neuron.bsky.social
A recap of what it does, what's new since the preprint, and code you can run on your own data.
cell.com/neuron/fullt...
A recap of what it does, what's new since the preprint, and code you can run on your own data.
cell.com/neuron/fullt...
Reposted by Zach Ladwig
How can we acquire new knowledge and skills on a daily basis while remaining the same person?
I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026:
doi.org/10.64898/202...
🧵👇
#neuroskyence #PsychSciSky
I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026:
doi.org/10.64898/202...
🧵👇
#neuroskyence #PsychSciSky
Functional brain organization is stable within individuals across years
Brain regions exhibit dynamic yet highly coordinated activity patterns that form large-scale functional networks measurable through resting-state correlations. While their association with fluctuating...
doi.org
June 11, 2026 at 10:17 PM
How can we acquire new knowledge and skills on a daily basis while remaining the same person?
I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026:
doi.org/10.64898/202...
🧵👇
#neuroskyence #PsychSciSky
I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026:
doi.org/10.64898/202...
🧵👇
#neuroskyence #PsychSciSky
Reposted by Zach Ladwig
New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n
May 20, 2026 at 10:45 PM
New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n
Reposted by Zach Ladwig
If chains are a fundamental organizational principle of cortex, how have we never noticed them before? The answer is that we are used to looking at data averaged across large groups, and group averaging hides them!
April 22, 2026 at 9:37 PM
If chains are a fundamental organizational principle of cortex, how have we never noticed them before? The answer is that we are used to looking at data averaged across large groups, and group averaging hides them!
Reposted by Zach Ladwig
Thanks to @beckmanillinois.bsky.social for a nice write up on our work:
beckman.illinois.edu/news/article...
beckman.illinois.edu/news/article...
May 19, 2026 at 2:40 PM
Thanks to @beckmanillinois.bsky.social for a nice write up on our work:
beckman.illinois.edu/news/article...
beckman.illinois.edu/news/article...
(1/5) Our paper is out now in Neuron!
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
May 18, 2026 at 11:17 PM
(1/5) Our paper is out now in Neuron!
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
Reposted by Zach Ladwig
Reposted by Zach Ladwig
Very excited about this project, led by @zachladwig.bsky.social
We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches.
Full🧵 coming soon!
We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches.
Full🧵 coming soon!
May 18, 2026 at 6:43 PM
Very excited about this project, led by @zachladwig.bsky.social
We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches.
Full🧵 coming soon!
We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches.
Full🧵 coming soon!
Reposted by Zach Ladwig
Individuals’ catenation maps were very similar. They all had dense catenation in prefrontal cortex, and moderate catenation in temporal, parietal, and insular cortex. Catenation was lowest in primary cortex and in parietal regions.
April 22, 2026 at 9:37 PM
Individuals’ catenation maps were very similar. They all had dense catenation in prefrontal cortex, and moderate catenation in temporal, parietal, and insular cortex. Catenation was lowest in primary cortex and in parietal regions.
Reposted by Zach Ladwig
I always assumed that brain function had to line up with cytoarchitectonics.
It turns out I was wrong.
Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams.
www.biorxiv.org/content/10.6...
It turns out I was wrong.
Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams.
www.biorxiv.org/content/10.6...
April 22, 2026 at 9:37 PM
I always assumed that brain function had to line up with cytoarchitectonics.
It turns out I was wrong.
Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams.
www.biorxiv.org/content/10.6...
It turns out I was wrong.
Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams.
www.biorxiv.org/content/10.6...