Zayna Chaker
@zaycha.bsky.social
Neuroscience, Stem Cells, Physiology, OMICs, Evolution, Modeling-lover
Team leader @IGFL (ENSdeLyon, CNRS),
Spatio-Temporal Logic of Adult Neurogenesis Group (ST-LAN)
Team leader @IGFL (ENSdeLyon, CNRS),
Spatio-Temporal Logic of Adult Neurogenesis Group (ST-LAN)
Reposted by Zayna Chaker
I am highly humbled to be this year recipient of the Pearl Meister Greengard Prize for outstanding women in biomedical research: its first awardee was my PhD advisor Nicole Le Douarin, an extraordinary scientist and mentor! Importantly, this award also recognizes the amazing scientists from my lab.
We are thrilled to announce that molecular biologist and neuroscientist Catherine Dulac of @harvardmcb.bsky.social is the 2026 winner of Rockefeller's Pearl Meister Greengard Prize!
Register now for the award ceremony on Oct 20.
#WomenInScience
🔗: https://bit.ly/3V2pZMA
Register now for the award ceremony on Oct 20.
#WomenInScience
🔗: https://bit.ly/3V2pZMA
September 24, 2026 at 8:11 AM
I am highly humbled to be this year recipient of the Pearl Meister Greengard Prize for outstanding women in biomedical research: its first awardee was my PhD advisor Nicole Le Douarin, an extraordinary scientist and mentor! Importantly, this award also recognizes the amazing scientists from my lab.
Reposted by Zayna Chaker
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
Wake-activated neuronal populations that regulate sleep drive - Nature
Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red...
www.nature.com
August 19, 2026 at 3:41 PM
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
Reposted by Zayna Chaker
Autre conséquence du libéralisme et de la recherche d’économies dans l’hôpital et les maternites : la mortalité des enfants de moins d’un an augmente de manière très inquiétante en France.
Le soutien aux services publics est un enjeu de santé publique majeur.
www.lemonde.fr/societe/arti...
Le soutien aux services publics est un enjeu de santé publique majeur.
www.lemonde.fr/societe/arti...
Hausse de la mortalité infantile : un rapport de l’IGAS « relativise » le rôle de la fermeture des petites maternités
Elévation de l’âge des femmes enceintes, précarité sociale, augmentation des grossesses multiples… L’inspection générale des affaires sociales, dans un rapport rendu public mercredi 5 août, livre sa p...
www.lemonde.fr
August 7, 2026 at 9:28 AM
Autre conséquence du libéralisme et de la recherche d’économies dans l’hôpital et les maternites : la mortalité des enfants de moins d’un an augmente de manière très inquiétante en France.
Le soutien aux services publics est un enjeu de santé publique majeur.
www.lemonde.fr/societe/arti...
Le soutien aux services publics est un enjeu de santé publique majeur.
www.lemonde.fr/societe/arti...
Reposted by Zayna Chaker
Finally out in @natneuro.nature.com!
A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work!
www.nature.com/articles/s41...
A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work!
www.nature.com/articles/s41...
Creating true and false memories from forgotten information in Drosophila - Nature Neuroscience
Forgotten memories in Drosophila persist as silent memory traces and can be recovered by reminder cues. Manipulating reminders can create false memories, showing that memory reconstruction flexibly in...
www.nature.com
July 31, 2026 at 7:41 AM
Finally out in @natneuro.nature.com!
A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work!
www.nature.com/articles/s41...
A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work!
www.nature.com/articles/s41...
Reposted by Zayna Chaker
A huge congratulations to Zheng and the entire Guo lab for this beautiful story! Very cool mechanism!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Intestinal stem cells count self-renewal divisions to switch multipotency - Nature
In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing ...
www.nature.com
July 30, 2026 at 10:34 AM
A huge congratulations to Zheng and the entire Guo lab for this beautiful story! Very cool mechanism!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Zayna Chaker
Our new paper on lipids in neural stem cell aging!!
Congratulations to Xiaoai Zhao for her fantastic work! ✨🥂
www.science.org/doi/10.1126/...
Congratulations to Xiaoai Zhao for her fantastic work! ✨🥂
www.science.org/doi/10.1126/...
Lipidomic profiling reveals age-dependent changes in plasma membrane lipids that affect neural stem cell aging
Plasma membrane lipids are remodeled with age in neural stem cells, and rejuvenating membrane lipids boosts old cell function.
www.science.org
July 29, 2026 at 11:55 PM
Our new paper on lipids in neural stem cell aging!!
Congratulations to Xiaoai Zhao for her fantastic work! ✨🥂
www.science.org/doi/10.1126/...
Congratulations to Xiaoai Zhao for her fantastic work! ✨🥂
www.science.org/doi/10.1126/...
Amazing work form @emiliepacary.bsky.social and Nora Abrous lab revealing a spatial molecular organisation of dentate gyrus compartments and a functional relevance on adult neurogenesis dynamics, just like shown in the V-SVZ a couple years ago by many groups! Congrats, and now the fun begins!🧠
🎉 Thrilled to share our latest preprint! This work would not have been possible without the invaluable contribution of José López Atalaya and his group. A huge thank you to everyone involved in this collaborative effort!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Blade-dependent molecular identity and neurogenic potential in the adult dentate gyrus
The dentate gyrus (DG) is a key hippocampal gateway for cognition and emotion and a major site of adult neurogenesis, yet its organization along the transverse (suprapyramidal–infrapyramidal) axis rem...
www.biorxiv.org
July 29, 2026 at 10:54 AM
Amazing work form @emiliepacary.bsky.social and Nora Abrous lab revealing a spatial molecular organisation of dentate gyrus compartments and a functional relevance on adult neurogenesis dynamics, just like shown in the V-SVZ a couple years ago by many groups! Congrats, and now the fun begins!🧠
Reposted by Zayna Chaker
🧠tenure-track position on #neurodev in @neuromarseille.bsky.social
👉our team at @ibdm.bsky.social is eligible to host a candidate.
Do not hesitate to contact me before the end of August!
neuro-marseille.org/en/blog/juni...
👉our team at @ibdm.bsky.social is eligible to host a candidate.
Do not hesitate to contact me before the end of August!
neuro-marseille.org/en/blog/juni...
Junior Group leader Position – NeuroDevelopment | NeuroMarseille
Call for Expression of Interest Registration on the Odyssée website will be open from July 23 to September 7 The NeuroMarseille Institute brings together 7 neuroscience laboratories, encompassing more
neuro-marseille.org
July 27, 2026 at 12:59 PM
🧠tenure-track position on #neurodev in @neuromarseille.bsky.social
👉our team at @ibdm.bsky.social is eligible to host a candidate.
Do not hesitate to contact me before the end of August!
neuro-marseille.org/en/blog/juni...
👉our team at @ibdm.bsky.social is eligible to host a candidate.
Do not hesitate to contact me before the end of August!
neuro-marseille.org/en/blog/juni...
A reminder that it is NOT all about neurons in the brain: amazing work from @loulierk.bsky.social lab showing new embryonic domains for the generation of astrocytic heterogeneity!
Delighted to share our work, which reveals a fascinating new aspect of #astrocyte diversity during brain development 🧠 Huge thanks to all co-authors, including our outstanding collaborators 🙏🏼
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Neocortical astrocyte diversity stems from distinct developmental origins
Key regulators of neural network activity in multiple advanced cognitive processes and essential components of the blood-brain barrier, astrocytes constitute a highly heterogeneous population at the m...
www.biorxiv.org
July 22, 2026 at 2:10 PM
A reminder that it is NOT all about neurons in the brain: amazing work from @loulierk.bsky.social lab showing new embryonic domains for the generation of astrocytic heterogeneity!
Reposted by Zayna Chaker
Our new paper is out in @nature.com!
We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females!
A remarkable mammalian parallel to bees and ants! 🐝🐜
@garyrlewin.bsky.social
youtu.be/enfv3zJrWKM?...
We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females!
A remarkable mammalian parallel to bees and ants! 🐝🐜
@garyrlewin.bsky.social
youtu.be/enfv3zJrWKM?...
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
youtu.be
July 15, 2026 at 4:10 PM
Our new paper is out in @nature.com!
We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females!
A remarkable mammalian parallel to bees and ants! 🐝🐜
@garyrlewin.bsky.social
youtu.be/enfv3zJrWKM?...
We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females!
A remarkable mammalian parallel to bees and ants! 🐝🐜
@garyrlewin.bsky.social
youtu.be/enfv3zJrWKM?...
Reposted by Zayna Chaker
Lab's latest: sculpting sex-biased metabolic territories in the intestine by tuning ploidy and lipid metabolism. Myc is to blame; Laura, Pedro and Chris found out www.cell.com/developmenta...
Myc sustains sex-biased organ zonation in the Drosophila intestine
Amourda, Blackie, Gaspar, et al. show that sex-biased activity of Dsx and Myc shapes
intestinal zonation and lipid metabolism in Drosophila. Elevated Myc activity in female
enterocytes increases ploid...
www.cell.com
June 30, 2026 at 5:09 PM
Lab's latest: sculpting sex-biased metabolic territories in the intestine by tuning ploidy and lipid metabolism. Myc is to blame; Laura, Pedro and Chris found out www.cell.com/developmenta...
Reposted by Zayna Chaker
Very insipring work from Magdalena Gotz lab - Nuclear proteome reveals microtubule-associated protein regulating fate and disease: Cell www.cell.com/cell/fulltex...
Nuclear proteome reveals microtubule-associated protein regulating fate and disease
Nuclear and cytoplasmic proteomics uncover a nuclear pool of cytoskeletal proteins,
including MAP1B, whose shuttling to the nucleus increases BRG1/BAF chromatin association
and regulates brain develop...
www.cell.com
June 26, 2026 at 11:39 AM
Very insipring work from Magdalena Gotz lab - Nuclear proteome reveals microtubule-associated protein regulating fate and disease: Cell www.cell.com/cell/fulltex...
Reposted by Zayna Chaker
The first course of Claude Desplan, invited Professor @college-de-france.fr is now available online. Next one today thursday June 4th at 4pm
www.college-de-france.fr/fr/agenda/co...
www.college-de-france.fr/fr/agenda/co...
Contributions spatiales et temporelles à la diversification neuronale | Collège de France
www.college-de-france.fr
June 4, 2026 at 10:16 AM
The first course of Claude Desplan, invited Professor @college-de-france.fr is now available online. Next one today thursday June 4th at 4pm
www.college-de-france.fr/fr/agenda/co...
www.college-de-france.fr/fr/agenda/co...
Amazing comparative study from @djabaudon.bsky.social lab between mus musculus and Acomys (spiny mouse) brain development!
Thrilled to shared our new preprint with @djabaudon.bsky.social ! Led by Ilaria Morassut, we explored "the extent to which early brain maturation requires interactions with the outside world". This wouldn't have been possible without our incredible collaborators, specially the @lanevol.bsky.social 🧵
June 3, 2026 at 2:10 PM
Amazing comparative study from @djabaudon.bsky.social lab between mus musculus and Acomys (spiny mouse) brain development!
🧠 IGFL External seminar | @dulaclab.bsky.social (Harvard/HHMI) deciphers the neural circuits underlying instinctive social behaviors (parenting, mating, aggression) and how the brain drives adaptive behavioral changes during sickness. What a treat! 🧠
June 1, 2026 at 9:28 AM
Reposted by Zayna Chaker
Very proud to host the great one and only Catherine Dulac @dulaclab.bsky.social at IGFL, @igflyon.bsky.social @ensdelyon.bsky.social, on June 1st 2026! I am all excited like a fan can be when meeting one of her idols 😱. Don't hesitate to join if you're in Lyon that day 🧠
May 12, 2026 at 1:06 PM
Very proud to host the great one and only Catherine Dulac @dulaclab.bsky.social at IGFL, @igflyon.bsky.social @ensdelyon.bsky.social, on June 1st 2026! I am all excited like a fan can be when meeting one of her idols 😱. Don't hesitate to join if you're in Lyon that day 🧠
Reposted by Zayna Chaker
From this thursday May 28th onwards, Claude Desplan @NYU will give four seminars as a guest Professor @college-de-france.fr Dont' miss this great colleague and teacher, on a super interesting and timely topic! Free access, no registration and an air-conditioned auditorium🤘
May 26, 2026 at 1:17 PM
From this thursday May 28th onwards, Claude Desplan @NYU will give four seminars as a guest Professor @college-de-france.fr Dont' miss this great colleague and teacher, on a super interesting and timely topic! Free access, no registration and an air-conditioned auditorium🤘
Reposted by Zayna Chaker
I deleted the previous post because it had a typo. If you could share, that would be great!
I'm very happy to announce that the "From Postdoc to PI Session" will be sponsored by the @biologists.bsky.social and we will be offering a $$ Prize to the best talk, so now a twofer reason to apply! www.germanfishmeeting.org/from-postoc-... Let me know if you have any question/s! 🐟
From Postoc to PI Session | German Fish Meeting
www.germanfishmeeting.org
May 14, 2026 at 6:01 AM
I deleted the previous post because it had a typo. If you could share, that would be great!
Reposted by Zayna Chaker
RegVelo introduces an end-to-end generative framework that jointly infers gene regulatory networks and developmental dynamic @cellcellpress.bsky.social @saukaspengler.bsky.social @fabiantheis.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
May 12, 2026 at 7:31 PM
RegVelo introduces an end-to-end generative framework that jointly infers gene regulatory networks and developmental dynamic @cellcellpress.bsky.social @saukaspengler.bsky.social @fabiantheis.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Very proud to host the great one and only Catherine Dulac @dulaclab.bsky.social at IGFL, @igflyon.bsky.social @ensdelyon.bsky.social, on June 1st 2026! I am all excited like a fan can be when meeting one of her idols 😱. Don't hesitate to join if you're in Lyon that day 🧠
May 12, 2026 at 1:06 PM
Very proud to host the great one and only Catherine Dulac @dulaclab.bsky.social at IGFL, @igflyon.bsky.social @ensdelyon.bsky.social, on June 1st 2026! I am all excited like a fan can be when meeting one of her idols 😱. Don't hesitate to join if you're in Lyon that day 🧠
So Proud of Marco Uderzo, a brilliant PhD student in my lab, talented coder and drawer in my lab, for winning the first prize of the artistic category of the EJN Neuroscience image! If you’re at @fens.org forum 2026, have a look at his piece!
🌟 The Winners of the European Journal of Neuroscience Image Competition 2026 are announced!🌟
👉️ Swipe to see more images from the competition!
🔗 Read more about the winning images and check out the other images selected to be featured on our website: buff.ly/hC5MLjR
@ejneuroscience.bsky.social
👉️ Swipe to see more images from the competition!
🔗 Read more about the winning images and check out the other images selected to be featured on our website: buff.ly/hC5MLjR
@ejneuroscience.bsky.social
May 8, 2026 at 7:54 PM
So Proud of Marco Uderzo, a brilliant PhD student in my lab, talented coder and drawer in my lab, for winning the first prize of the artistic category of the EJN Neuroscience image! If you’re at @fens.org forum 2026, have a look at his piece!
Very happy to host @OrianeMauger from the @maxplanck.bsky.social Munich @igflyon.bsky.social: very inspiring talk from a kind and generous young scientist and friend!
May 4, 2026 at 9:19 AM
Very happy to host @OrianeMauger from the @maxplanck.bsky.social Munich @igflyon.bsky.social: very inspiring talk from a kind and generous young scientist and friend!
Reposted by Zayna Chaker
Scientific misconduct is not merely manipulating figures in a publication, getting caught and retracting papers. It has many other facets, some of which still being subjects to different perceptions by the scientists themselves, while they should not. Two classical examples:
May 2, 2026 at 12:52 PM
Scientific misconduct is not merely manipulating figures in a publication, getting caught and retracting papers. It has many other facets, some of which still being subjects to different perceptions by the scientists themselves, while they should not. Two classical examples:
Reposted by Zayna Chaker
NEWS: The ERC Scientific Council has listened to the concerns from members of the research community about changes to the re-submission rules, intended to manage the surge in demand for grants.
The Scientific Council will readjust some of the changes: link.europa.eu/TBqRQJ
The Scientific Council will readjust some of the changes: link.europa.eu/TBqRQJ
ERC Scientific Council readjusts rules for reapplication
The ERC Scientific Council has listened to the concerns from members of the research community about the recent announcement on changes to the re-submission rules. The changes, intended to manage the ...
link.europa.eu
April 29, 2026 at 2:25 PM
NEWS: The ERC Scientific Council has listened to the concerns from members of the research community about changes to the re-submission rules, intended to manage the surge in demand for grants.
The Scientific Council will readjust some of the changes: link.europa.eu/TBqRQJ
The Scientific Council will readjust some of the changes: link.europa.eu/TBqRQJ
Reposted by Zayna Chaker
Signed. The message should be clear; supporting science progress is not delivered by restrictions of the chances of excellent people to apply. More funding should be allocated to support science, globally and in this case in Europe.
What should Europe do when demand for #ERC funding keeps rising?
Restrict access or invest in excellence?
Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness
Consider to share & sign - see below 🧪
Restrict access or invest in excellence?
Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness
Consider to share & sign - see below 🧪
#erc | Johanna Joyce
What should Europe do when demand for its most successful frontier research programme keeps rising?
Restrict access, or invest in the excellence it has created?
A new open letter, spearheaded by Sara...
www.linkedin.com
April 22, 2026 at 6:08 PM
Signed. The message should be clear; supporting science progress is not delivered by restrictions of the chances of excellent people to apply. More funding should be allocated to support science, globally and in this case in Europe.