Ahmet O. Ceceli
aoceceli.bsky.social
Ahmet O. Ceceli
@aoceceli.bsky.social
Director, Ceceli Cognitive Control Lab. Asst professor of Psychiatry and Neuroscience @ Mt. Sinai. Studying the neuroscience of self-control, goals, and habits.
Reposted by Ahmet O. Ceceli
A Hot Topics article suggests that combining pharmacological and behavioral approaches to target dysfunctional prefrontal circuits is a promising approach to reduce relapse in addiction @aoceceli.bsky.social @narcatms.bsky.social

www.nature.com/articles/s41...
Restoring prefrontal function with dopaminergic enhancement of memory updating in addiction - Neuropsychopharmacology
Neuropsychopharmacology - Restoring prefrontal function with dopaminergic enhancement of memory updating in addiction
www.nature.com
July 28, 2026 at 7:19 PM
Thanks, Alberto!
July 28, 2026 at 6:50 PM
Reposted by Ahmet O. Ceceli
Semaglutide reduces depression risk by 44%, anxiety by 38%, and substance use disorder by 47% (other GLP1s had lower or no effect).
That said, it the failed Alzheimer/GLP1 trial taught us something, it's that confirmatory RCTs are essential.
linkinghub.elsevier.com/retrieve/pi...
Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study
People with diabetes have an elevated risk of developing depression, anxiety, and suicide. GLP-1 receptor agonists are licensed to treat diabetes and …
linkinghub.elsevier.com
March 25, 2026 at 12:38 AM