BumJin Ko
@bumjinko.bsky.social
Neuroscience Postdoc in @denisejcai lab at Mount Sinai | Memory & Cognition | Persistence 🙏🏾 | he/him
Reposted by BumJin Ko
Our work on goal-directed theta sweeps is out! We found two different types of theta sweeps in the rat hippocampus. During random foraging, left-right alternating sweeps dominated (Vollan, 25). However, during memory-guided navigation sweeps pointing to hidden goal locations emerged with learning.
July 6, 2026 at 10:51 AM
Our work on goal-directed theta sweeps is out! We found two different types of theta sweeps in the rat hippocampus. During random foraging, left-right alternating sweeps dominated (Vollan, 25). However, during memory-guided navigation sweeps pointing to hidden goal locations emerged with learning.
Reposted by BumJin Ko
Very excited for our new paper, now out in
@cellcellpress.bsky.social! /🧵
The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...
@cellcellpress.bsky.social! /🧵
The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...
Arc mediates intercellular tau transmission via extracellular vesicles
Tau pathology spreads cell to cell, but the mechanisms of intercellular tau transmission remain unclear. We find that the neuronal gene Arc is critica…
authors.elsevier.com
June 29, 2026 at 4:49 PM
Very excited for our new paper, now out in
@cellcellpress.bsky.social! /🧵
The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...
@cellcellpress.bsky.social! /🧵
The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...
Reposted by BumJin Ko
Please join us in welcoming incoming chairs @tinakim-neuro.bsky.social & @gisellavetere.bsky.social, and newly elected vice-chairs @tristanshuman.bsky.social & @lindsayschwarz.bsky.social.
We can’t wait to see what this team has in store for #OptoGRC2028!
We can’t wait to see what this team has in store for #OptoGRC2028!
May 26, 2026 at 7:48 PM
Please join us in welcoming incoming chairs @tinakim-neuro.bsky.social & @gisellavetere.bsky.social, and newly elected vice-chairs @tristanshuman.bsky.social & @lindsayschwarz.bsky.social.
We can’t wait to see what this team has in store for #OptoGRC2028!
We can’t wait to see what this team has in store for #OptoGRC2028!
Reposted by BumJin Ko
Woo!!!!!! PenningtonLab.com is live!
Pennington Lab
PenningtonLab.com
May 13, 2026 at 8:35 PM
Woo!!!!!! PenningtonLab.com is live!
Reposted by BumJin Ko
Full band in the studio this summer! LP coming soon.
May 8, 2026 at 5:16 PM
Full band in the studio this summer! LP coming soon.
Reposted by BumJin Ko
Our latest publication grapples with how the brain could implement gradient descent by sending learning targets top-down, gating plasticity with dendritic inhibition, and updating synaptic weights with biologically observed learning rules like BTSP.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
March 27, 2026 at 10:29 AM
Our latest publication grapples with how the brain could implement gradient descent by sending learning targets top-down, gating plasticity with dendritic inhibition, and updating synaptic weights with biologically observed learning rules like BTSP.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by BumJin Ko
How does neuronal gene expression evolve over time in response to experience? CytoTape will help us find out - a major milestone for neuroscience, providing new ways to study memory & aging 🧠
Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉
Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...
February 6, 2026 at 4:24 PM
How does neuronal gene expression evolve over time in response to experience? CytoTape will help us find out - a major milestone for neuroscience, providing new ways to study memory & aging 🧠
Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉
Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉
Reposted by BumJin Ko
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...
January 26, 2026 at 8:50 PM
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...
Reposted by BumJin Ko
Wow, such an insightful and substantive open floor discussion at last night's Memory Hub meeting! 🤓
Do we need ANY of the same synapses that were active during learning to be reactivated to recall a memory? Lines have been drawn and sides taken!
Do we need ANY of the same synapses that were active during learning to be reactivated to recall a memory? Lines have been drawn and sides taken!
December 3, 2025 at 4:43 PM
Wow, such an insightful and substantive open floor discussion at last night's Memory Hub meeting! 🤓
Do we need ANY of the same synapses that were active during learning to be reactivated to recall a memory? Lines have been drawn and sides taken!
Do we need ANY of the same synapses that were active during learning to be reactivated to recall a memory? Lines have been drawn and sides taken!
Reposted by BumJin Ko
The Cai & Shuman Labs threw an EPIC White Elephant party! So much holiday cheer packed into one room.
We did not have a partridge in a pear tree, but we did have:
👥 25 members laughing
🥔 6 chip-bags-a-gifting
🪴 5 plants-afloating
🦫...and a capybara in a knit hat!
We did not have a partridge in a pear tree, but we did have:
👥 25 members laughing
🥔 6 chip-bags-a-gifting
🪴 5 plants-afloating
🦫...and a capybara in a knit hat!
December 12, 2025 at 8:53 PM
The Cai & Shuman Labs threw an EPIC White Elephant party! So much holiday cheer packed into one room.
We did not have a partridge in a pear tree, but we did have:
👥 25 members laughing
🥔 6 chip-bags-a-gifting
🪴 5 plants-afloating
🦫...and a capybara in a knit hat!
We did not have a partridge in a pear tree, but we did have:
👥 25 members laughing
🥔 6 chip-bags-a-gifting
🪴 5 plants-afloating
🦫...and a capybara in a knit hat!
Reposted by BumJin Ko
Excited to share new work from our lab at #SfN2025! @sfn.org
Posters on how the brain learns about time and space—from foraging and MEC dynamics, to RNN + hippocampus in curriculum learning, to MTL vs striatal activity across learning, and cognitive aging in social isolation stress. Check them out!
Posters on how the brain learns about time and space—from foraging and MEC dynamics, to RNN + hippocampus in curriculum learning, to MTL vs striatal activity across learning, and cognitive aging in social isolation stress. Check them out!
November 13, 2025 at 3:47 PM
Reposted by BumJin Ko
We're presenting Miniscope Zero, the first fully-wireless Miniscope, at #SfN25! Wireless power + data enable long-term neural recordings from multiple freely behaving animals. @MiniscopeTeam
Poster: Nov. 17, 1–5 pm, ZZ7
Info: tinyurl.com/mhdfb67u
Full video: youtu.be/mIt15LA-rZI?...
Poster: Nov. 17, 1–5 pm, ZZ7
Info: tinyurl.com/mhdfb67u
Full video: youtu.be/mIt15LA-rZI?...
November 16, 2025 at 5:57 PM
We're presenting Miniscope Zero, the first fully-wireless Miniscope, at #SfN25! Wireless power + data enable long-term neural recordings from multiple freely behaving animals. @MiniscopeTeam
Poster: Nov. 17, 1–5 pm, ZZ7
Info: tinyurl.com/mhdfb67u
Full video: youtu.be/mIt15LA-rZI?...
Poster: Nov. 17, 1–5 pm, ZZ7
Info: tinyurl.com/mhdfb67u
Full video: youtu.be/mIt15LA-rZI?...
Reposted by BumJin Ko
Excited for my group's #SfN posters tomorrow (Nov. 17, 1–5 PM)!
We will be presenting new #Miniscopes, neural recording tools, calcium image processing, and data infrastructure advances.
If you’re at the meeting, stop by posters ZZ7–ZZ14!
We will be presenting new #Miniscopes, neural recording tools, calcium image processing, and data infrastructure advances.
If you’re at the meeting, stop by posters ZZ7–ZZ14!
November 17, 2025 at 2:05 AM
Excited for my group's #SfN posters tomorrow (Nov. 17, 1–5 PM)!
We will be presenting new #Miniscopes, neural recording tools, calcium image processing, and data infrastructure advances.
If you’re at the meeting, stop by posters ZZ7–ZZ14!
We will be presenting new #Miniscopes, neural recording tools, calcium image processing, and data infrastructure advances.
If you’re at the meeting, stop by posters ZZ7–ZZ14!
Reposted by BumJin Ko
Reunion with past and present Cai lab & Shuman lab members (and collaborators). Spending time with you guys is easily the best part of my job.
@tristanshuman.bsky.social
@sinaibrain.bsky.social
@sfn.org
@tristanshuman.bsky.social
@sinaibrain.bsky.social
@sfn.org
November 17, 2025 at 7:31 AM
Reunion with past and present Cai lab & Shuman lab members (and collaborators). Spending time with you guys is easily the best part of my job.
@tristanshuman.bsky.social
@sinaibrain.bsky.social
@sfn.org
@tristanshuman.bsky.social
@sinaibrain.bsky.social
@sfn.org
Reposted by BumJin Ko
🧠 The Cai Lab will be at #SfN25!
Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
November 13, 2025 at 7:17 PM
🧠 The Cai Lab will be at #SfN25!
Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
Reposted by BumJin Ko
We're brewing up some Halloween fun in the Cai & Shuman Labs! ⚗️🎃
Just look at all the creativity everyone poured into their costumes! We have the coolest crew 👩🔬🧪
Just look at all the creativity everyone poured into their costumes! We have the coolest crew 👩🔬🧪
October 31, 2025 at 5:34 PM
We're brewing up some Halloween fun in the Cai & Shuman Labs! ⚗️🎃
Just look at all the creativity everyone poured into their costumes! We have the coolest crew 👩🔬🧪
Just look at all the creativity everyone poured into their costumes! We have the coolest crew 👩🔬🧪
Reposted by BumJin Ko
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Falling asleep follows a predictable bifurcation dynamic - Nature Neuroscience
Li et al. propose a conceptual framework to study the phenomenon of falling asleep based on electroencephalogram data. They show that a tipping point marks the brain’s nonlinear wake-to-sleep transiti...
www.nature.com
October 28, 2025 at 5:35 PM
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by BumJin Ko
Always fun talking with @denisejcai.bsky.social & @joezaki.bsky.social. Listen in for our conversation about mentor-mentee relationships, where we discuss choosing a mentor, following your joy, what it's really like to work with Denise, and more!!
It has been an immense honor to learn & grow with two of the greatest scientists I know: @zachtpennington.bsky.social & @joezaki.bsky.social 🧑🔬
Listen in on our conversation about mentorship, building trust and creating a safe space to disagree: neuronline.sfn.org/professional...
Listen in on our conversation about mentorship, building trust and creating a safe space to disagree: neuronline.sfn.org/professional...
October 3, 2025 at 10:34 PM
Always fun talking with @denisejcai.bsky.social & @joezaki.bsky.social. Listen in for our conversation about mentor-mentee relationships, where we discuss choosing a mentor, following your joy, what it's really like to work with Denise, and more!!
Reposted by BumJin Ko
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
October 2, 2025 at 3:46 PM
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
Reposted by BumJin Ko
OUT NOW! "Think Alike?": A Neuronline SfN
Podcast | "Diverging Ideas, Shared Goal". In this episode, Drs. @joezaki.bsky.social & Zach Pennington join mentor Dr.
@denisejcai.bsky.social to reflect on the journey of building a neuroscience lab from the ground up🎤 neuronline.sfn.org/professional...
Podcast | "Diverging Ideas, Shared Goal". In this episode, Drs. @joezaki.bsky.social & Zach Pennington join mentor Dr.
@denisejcai.bsky.social to reflect on the journey of building a neuroscience lab from the ground up🎤 neuronline.sfn.org/professional...
October 2, 2025 at 5:09 PM
OUT NOW! "Think Alike?": A Neuronline SfN
Podcast | "Diverging Ideas, Shared Goal". In this episode, Drs. @joezaki.bsky.social & Zach Pennington join mentor Dr.
@denisejcai.bsky.social to reflect on the journey of building a neuroscience lab from the ground up🎤 neuronline.sfn.org/professional...
Podcast | "Diverging Ideas, Shared Goal". In this episode, Drs. @joezaki.bsky.social & Zach Pennington join mentor Dr.
@denisejcai.bsky.social to reflect on the journey of building a neuroscience lab from the ground up🎤 neuronline.sfn.org/professional...
Reposted by BumJin Ko
Excited to share that I landed my dream job!🎉🎉🎉 The Pennington Lab will be opening at the University of British Columbia in January 2026!
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
September 29, 2025 at 4:31 PM
Excited to share that I landed my dream job!🎉🎉🎉 The Pennington Lab will be opening at the University of British Columbia in January 2026!
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social
Reposted by BumJin Ko
So excited for this! Can't wait to see everyone there!
We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠
September 24, 2025 at 8:06 PM
So excited for this! Can't wait to see everyone there!
Reposted by BumJin Ko
Looking forward to tomorrow's "Perspectives Across Biology" panel at the @chanzuckerberg.bsky.social Imaging the Future meeting! If you're at CZI this week, come check it out and join the conversation 🧑🔬
September 17, 2025 at 7:59 PM
Looking forward to tomorrow's "Perspectives Across Biology" panel at the @chanzuckerberg.bsky.social Imaging the Future meeting! If you're at CZI this week, come check it out and join the conversation 🧑🔬
Reposted by BumJin Ko
What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
July 14, 2025 at 4:55 PM
What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Reposted by BumJin Ko
Excited to share our latest paper - now out in @science.org - we showed how oxytocin modulates maternally-directed behavior in young mice (P15).
September 12, 2025 at 3:21 PM
Excited to share our latest paper - now out in @science.org - we showed how oxytocin modulates maternally-directed behavior in young mice (P15).