Carolina Cabalín
@carolinacabalin.bsky.social
📍🇨🇱&🇺🇸🗽|👩🔬 PhD | Skin immunology, Infections, T cells, & Cancer immunology | Instructor & PostDoc | PUC WCM Tri-I MSKCC | Pew Latin American Fellow 2024 | Biochemist | Founder of InverSkin 🌍🚀🏐🐶🐱👩🍳🍀🌵
Pinned
This week has been full of wonderful scientific news ✨👩🏼🔬
Can dietary interventions change how fast genomes accumulate mutations with age?
Caloric restriction modulates genome-wide somatic mutation in mice: Cell www.cell.com/cell/fulltex...
Caloric restriction modulates genome-wide somatic mutation in mice: Cell www.cell.com/cell/fulltex...
Caloric restriction modulates genome-wide somatic mutation in mice
Mutations accumulate in cells with age, while caloric restriction extends lifespan
across diverse animals. Grońska-Pęski et al. study the effect of caloric restriction
on mutations genome-wide in mice...
www.cell.com
September 13, 2026 at 6:40 PM
Can dietary interventions change how fast genomes accumulate mutations with age?
Caloric restriction modulates genome-wide somatic mutation in mice: Cell www.cell.com/cell/fulltex...
Caloric restriction modulates genome-wide somatic mutation in mice: Cell www.cell.com/cell/fulltex...
Reposted by Carolina Cabalín
The Separable Organization of Immune Transcriptional Responses https://www.biorxiv.org/content/10.64898/2026.09.09.750474v1
September 13, 2026 at 2:15 PM
The Separable Organization of Immune Transcriptional Responses https://www.biorxiv.org/content/10.64898/2026.09.09.750474v1
Reposted by Carolina Cabalín
Impaired regulation by purinergic signaling axis contributes to CD8+ T cell dysregulation in STAT3 gain of function @insight.jci.org @sarahhenrickson.bsky.social @childrensphila.bsky.social
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
September 11, 2026 at 4:36 PM
Impaired regulation by purinergic signaling axis contributes to CD8+ T cell dysregulation in STAT3 gain of function @insight.jci.org @sarahhenrickson.bsky.social @childrensphila.bsky.social
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
Reposted by Carolina Cabalín
PRMT7 restricts CD8+ T cells expansion via the NF-ΚB pathway @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 7, 2026 at 9:43 PM
PRMT7 restricts CD8+ T cells expansion via the NF-ΚB pathway @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Carolina Cabalín
August 31, 2026 at 7:03 PM
Reposted by Carolina Cabalín
PD-1 regulates CD4+ T cell-mediated CD8+ T cell responses in the brain to balance viral control and neuroinflammation
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
PD-1 regulates CD4+ T cell-mediated CD8+ T cell responses in the brain to balance viral control and neuroinflammation - Nature Communications
JC polyomavirus infection can result in progressive multifocal leukoencephalopathy, and T cells have been shown to express PD-1. Here the authors show that PD-1 regulates the CD4+ T cell mediated CD8+...
www.nature.com
August 18, 2026 at 8:39 PM
PD-1 regulates CD4+ T cell-mediated CD8+ T cell responses in the brain to balance viral control and neuroinflammation
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
Reposted by Carolina Cabalín
Candida auris represses host antifungal defense to establish a favorable cutaneous niche @science.org @arimolofskylab.bsky.social #Noble
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
August 6, 2026 at 8:21 PM
Candida auris represses host antifungal defense to establish a favorable cutaneous niche @science.org @arimolofskylab.bsky.social #Noble
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Carolina Cabalín
Fibroblasts resist Staphylococcus aureus on the skin surface by responding to IL-1 and recruiting neutrophils
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
August 13, 2026 at 7:12 PM
Fibroblasts resist Staphylococcus aureus on the skin surface by responding to IL-1 and recruiting neutrophils
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Carolina Cabalín
Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @mdanderson.bsky.social
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @mdanderson.bsky.social
August 6, 2026 at 8:05 PM
Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @mdanderson.bsky.social
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @mdanderson.bsky.social
Reposted by Carolina Cabalín
CCR7+ activated dendritic cells are essential for spontaneous and immunotherapy-driven anti-tumor immunity @cp-immunity.bsky.social @mariakoufaki.bsky.social @santiagozelenay.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
August 4, 2026 at 6:30 PM
CCR7+ activated dendritic cells are essential for spontaneous and immunotherapy-driven anti-tumor immunity @cp-immunity.bsky.social @mariakoufaki.bsky.social @santiagozelenay.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
🎉 Our preprint is now live on medRxiv! Happy to share our latest work with D. González-Diez and @drarturo. We found that atopic derm web searches track anomalous atmospheric humidity rather than chronic dryness. We welcome your feedback!
#AtopicDermatitis
#AtopicDermatitis
August 4, 2026 at 12:22 AM
🎉 Our preprint is now live on medRxiv! Happy to share our latest work with D. González-Diez and @drarturo. We found that atopic derm web searches track anomalous atmospheric humidity rather than chronic dryness. We welcome your feedback!
#AtopicDermatitis
#AtopicDermatitis
Reposted by Carolina Cabalín
Circadian timing of antigen exposure programs CD8+ T cell memory and tunes antiviral immunity
www.science.org/doi/10.1126/...
@laurakervezee.bsky.social @unileiden.bsky.social
www.science.org/doi/10.1126/...
@laurakervezee.bsky.social @unileiden.bsky.social
July 31, 2026 at 8:32 PM
Circadian timing of antigen exposure programs CD8+ T cell memory and tunes antiviral immunity
www.science.org/doi/10.1126/...
@laurakervezee.bsky.social @unileiden.bsky.social
www.science.org/doi/10.1126/...
@laurakervezee.bsky.social @unileiden.bsky.social
Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens | Nature Immunology share.google/sBXf2gYJvJjl...
Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens - Nature Immunology
Unlike in other tissues, lung-resident memory T cell populations are not well maintained in mice. Here the authors show that this is not the case in human lungs, where tissue-resident memory T cells specific to a variety of pathogens can persist for many years.
share.google
July 29, 2026 at 4:04 PM
Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens | Nature Immunology share.google/sBXf2gYJvJjl...
Reposted by Carolina Cabalín
SIGLEC1 FACILITATES MACROPHAGE-CD8+ T CELL INTERACTIONS AND CORRELATES WITH CANCER IMMUNOTHERAPY RESPONSE https://www.biorxiv.org/content/10.64898/2026.07.09.737484v1
July 15, 2026 at 8:17 PM
SIGLEC1 FACILITATES MACROPHAGE-CD8+ T CELL INTERACTIONS AND CORRELATES WITH CANCER IMMUNOTHERAPY RESPONSE https://www.biorxiv.org/content/10.64898/2026.07.09.737484v1
Reposted by Carolina Cabalín
A high-fat, low-carbohydrate diet can feed intestinal tumours
A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.
www.nature.com/artic...
1/2
A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.
www.nature.com/artic...
1/2
A high-fat, low-carbohydrate diet can feed intestinal tumours
Nature - A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.
www.nature.com
July 16, 2026 at 9:01 AM
A high-fat, low-carbohydrate diet can feed intestinal tumours
A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.
www.nature.com/artic...
1/2
A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.
www.nature.com/artic...
1/2
Reposted by Carolina Cabalín
There’s poop on the lettuce. There’s worms in the beef. There’s glass in the bread.
What kind of Upton Sinclair timeline is this
What kind of Upton Sinclair timeline is this
July 16, 2026 at 3:19 PM
There’s poop on the lettuce. There’s worms in the beef. There’s glass in the bread.
What kind of Upton Sinclair timeline is this
What kind of Upton Sinclair timeline is this
Reposted by Carolina Cabalín
Looking for ways to keep your excitement for science?!
Come to our NYC Postdocs Night Science event July 29th! We're meeting in Mount Sinai for a night science session to improve and practice our creative process! Free RSVP:
docs.google.com/forms/d/e/1F...
@kelseymonson.bsky.social
Come to our NYC Postdocs Night Science event July 29th! We're meeting in Mount Sinai for a night science session to improve and practice our creative process! Free RSVP:
docs.google.com/forms/d/e/1F...
@kelseymonson.bsky.social
July 13, 2026 at 4:45 PM
Looking for ways to keep your excitement for science?!
Come to our NYC Postdocs Night Science event July 29th! We're meeting in Mount Sinai for a night science session to improve and practice our creative process! Free RSVP:
docs.google.com/forms/d/e/1F...
@kelseymonson.bsky.social
Come to our NYC Postdocs Night Science event July 29th! We're meeting in Mount Sinai for a night science session to improve and practice our creative process! Free RSVP:
docs.google.com/forms/d/e/1F...
@kelseymonson.bsky.social
Reposted by Carolina Cabalín
Nadine Cerf-Bensussan, longtime Mucosal Immunology editor, has been awarded the Brian Kelsall Medal for her work with the journal. Thanks Nadine for all your efforts! #ICMI2026
July 13, 2026 at 10:05 PM
Nadine Cerf-Bensussan, longtime Mucosal Immunology editor, has been awarded the Brian Kelsall Medal for her work with the journal. Thanks Nadine for all your efforts! #ICMI2026
Reposted by Carolina Cabalín
Review @natrevimmunol.nature.com
The challenge and promise of studying human antigen-specific T cells
www.nature.com/articles/s41...
The challenge and promise of studying human antigen-specific T cells
www.nature.com/articles/s41...
The challenge and promise of studying human antigen-specific T cells - Nature Reviews Immunology
Antigen-specific T cells underpin immunity, cancer surveillance and autoimmunity, yet remain difficult to study. This Review describes the technologies and computational approaches that are helping to...
www.nature.com
July 13, 2026 at 8:37 PM
Review @natrevimmunol.nature.com
The challenge and promise of studying human antigen-specific T cells
www.nature.com/articles/s41...
The challenge and promise of studying human antigen-specific T cells
www.nature.com/articles/s41...
Reposted by Carolina Cabalín
Diet–microbiome synergy underlies obesity-associated immunotherapy efficacy @nature.com @mcgilluniversity.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 8, 2026 at 4:41 PM
Diet–microbiome synergy underlies obesity-associated immunotherapy efficacy @nature.com @mcgilluniversity.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Carolina Cabalín
Sequential infection reprograms the immune landscape to shape future responses https://www.biorxiv.org/content/10.64898/2026.06.26.734836v1
July 1, 2026 at 8:16 PM
Sequential infection reprograms the immune landscape to shape future responses https://www.biorxiv.org/content/10.64898/2026.06.26.734836v1
Determinants and clinical associations of total, bioavailable, and free 25-hydroxyvitamin D in children with atopic dermatitis
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Determinants and clinical associations of total, bioavailable, and free 25-hydroxyvitamin D in children with atopic dermatitis - Archives of Dermatological Research
Low vitamin D (VD) status is prevalent in children with atopic dermatitis (AD) and, in some populations, is associated with disease severity. Circulating bioavailable and free 25-hydroxyvitamin D (25(...
link.springer.com
June 30, 2026 at 5:38 PM
Determinants and clinical associations of total, bioavailable, and free 25-hydroxyvitamin D in children with atopic dermatitis
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Carolina Cabalín
Maintenance DNA methylation is necessary for age-related alterations in regulatory T cell transcriptional and DNA methylation signatures https://www.biorxiv.org/content/10.64898/2026.06.24.733005v1
June 29, 2026 at 11:16 PM
Maintenance DNA methylation is necessary for age-related alterations in regulatory T cell transcriptional and DNA methylation signatures https://www.biorxiv.org/content/10.64898/2026.06.24.733005v1
Reposted by Carolina Cabalín
Just announced: Meet Pew's new class of biomedical scholars and fellows!
Together, these 36 scientists make up the 2026 class of:
🔬 Pew Biomedical Scholars
🩺 Pew-Stewart Scholars for Cancer Research
🧪 Pew Latin American Fellows
Check out how they're driving discovery across health and medicine 👇
Together, these 36 scientists make up the 2026 class of:
🔬 Pew Biomedical Scholars
🩺 Pew-Stewart Scholars for Cancer Research
🧪 Pew Latin American Fellows
Check out how they're driving discovery across health and medicine 👇
These 36 Scientists Are Leading the Way to Biomedical Discoveries
On June 16, Pew announced the 2026 class of Pew Scholars Program in the Biomedical Sciences, Pew Latin American Fellows Program in the Biomedical Sciences, and Pew-Stewart Scholars Program for Cancer ...
www.pew.org
June 16, 2026 at 4:17 PM
Just announced: Meet Pew's new class of biomedical scholars and fellows!
Together, these 36 scientists make up the 2026 class of:
🔬 Pew Biomedical Scholars
🩺 Pew-Stewart Scholars for Cancer Research
🧪 Pew Latin American Fellows
Check out how they're driving discovery across health and medicine 👇
Together, these 36 scientists make up the 2026 class of:
🔬 Pew Biomedical Scholars
🩺 Pew-Stewart Scholars for Cancer Research
🧪 Pew Latin American Fellows
Check out how they're driving discovery across health and medicine 👇
Reposted by Carolina Cabalín
Preprint: Single-cell gain-of-function mapping reveals latent regulatory programs governing CD8+ T cell fate
www.researchsquare.com/article/rs-9...
www.researchsquare.com/article/rs-9...
June 15, 2026 at 2:06 PM
Preprint: Single-cell gain-of-function mapping reveals latent regulatory programs governing CD8+ T cell fate
www.researchsquare.com/article/rs-9...
www.researchsquare.com/article/rs-9...