ching-hochang.bsky.social
@ching-hochang.bsky.social
Now, the next chapter!

Our lab at the Institute of Molecular Biology, Academia Sinica in Taiwan, is fully up and running. We are actively recruiting passionate researchers at all levels to tackle bold ideas in cell biology, chromosome architecture, and evolution:

sites.google.com/view/ecg-lab...
ECG LAB
"The only constant in life is change." — Heraclitus Genetic conflicts — the good, the bad, and the ugly — shape our lives over time We aim to understand why even the most essential genes and chrom...
sites.google.com
October 8, 2026 at 1:23 AM
I also want to remember the late Meng-Chao Yao. His wisdom, kindness, and unwavering encouragement during my postdoc years and faculty job searches meant a lot to me. I am deeply grateful for his mentorship.
October 8, 2026 at 1:23 AM
This work would not have been possible without incredible mentors and colleagues.

Huge thanks to Harmit Malik, Amanda Larracuente, Yukiko Yamashita, Benjamin Loppin, Barbara Wakimoto, Steve Henikoff, Kami Ahmad and many people for invaluable feedback, insights, and discussions over the years.
October 8, 2026 at 1:23 AM
Thrilled to share that our paper is finally out in Science Advances!
🔗 www.science.org/doi/10.1126/...

TL;DR: A Drosophila protamine acts as shields resolving conflict between X and Y chromosomes. Disruption unleashes meiotic drive that kills X-bearing sperm and skews progeny sex ratios. 🪰🧬ᯡ
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Although essential for sperm function, protamines evolve rapidly for reasons that remain unknown. Using in vivo gene replac...
www.science.org
October 8, 2026 at 1:23 AM
Finally, a huge thank you to my mentors Chau-Ti Ting, Amanda Larracuente and @harmitmalik.bsky.social, collaborators, and friends for their support. Special credit to Harmit for the lab name and logo inspiration.
July 11, 2025 at 8:23 PM
We’re actively recruiting at all levels: RAs, MS students, PhD students, and postdocs. If you’re passionate about evolutionary biology and excited to explore how lives are shaped by genetic conflicts, we’d love to hear from you! sites.google.com/view/ecg-lab...
July 11, 2025 at 8:23 PM
At ECG, we aim to understand why even the most essential genes and chromosome structures evolve—using a combination of genetic, genomic, and cellular approaches. We’re driven by curiosity and open to creative thinking across disciplines.
July 11, 2025 at 8:23 PM