@daanoverwijn.bsky.social
Reposted
🚀 New preprint 🥳 Fantastic work by our recent PhD graduate Daan !
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
PAIP1 couples mRNA export to cytoplasmic mRNP remodeling and poly(A) homeostasis https://www.biorxiv.org/content/10.64898/2026.07.31.742013v1
August 3, 2026 at 2:45 PM
🚀 New preprint 🥳 Fantastic work by our recent PhD graduate Daan !
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.
How are mRNPs remodeled as they exit the nucleus?
We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation.