Emily Warman
@ewarman.bsky.social
Microbiology postdoc at the University of Birmingham
Reposted by Emily Warman
In our most recent work David Forrest has discovered a widespread mechanisms linking transcription initiation to DNA supercoiling...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The bacterial RNA polymerase-associated CarD protein couples promoter activity to DNA supercoiling - Nature Communications
The transcription factor CarD facilitates the activation of transcription in many bacteria and in Rhodobacter sphaeroides, CarD compensates for suboptimal promoter DNA sequences. Here, the authors sho...
www.nature.com
February 6, 2026 at 3:36 PM
In our most recent work David Forrest has discovered a widespread mechanisms linking transcription initiation to DNA supercoiling...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Emily Warman
@ewarman.bsky.social has followed up on her discovery of bidirectional promoters in bacteria by defining their basic rules for regulation and links to gene expression noise...
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Bidirectional promoters in Escherichia coli: regulatory rules and implications for gene expression noise
Abstract. In prokaryotes, bidirectional promoters are pseudo-symmetrical DNA sequences that stimulate divergent transcription. Ubiquitous, and far more lik
academic.oup.com
February 6, 2026 at 3:35 PM
@ewarman.bsky.social has followed up on her discovery of bidirectional promoters in bacteria by defining their basic rules for regulation and links to gene expression noise...
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...