Ezra Winter-Nelson
ewinternelson.bsky.social
Ezra Winter-Nelson
@ewinternelson.bsky.social
Postdoc with Menon Lab/CTCN @ Columbia. Previously: Wig Neuroimaging Lab @ UTD. Interests include: network neuroscience, evolution, complexity, individual differences, and the Lakers.
Reposted by Ezra Winter-Nelson
Combining data to study lifespan brain aging is tempting: more data and wider age range! But mixing data across scanners/protocols without proper harmonization can bias age effects, including studies using high-quality HCP data.

Imaging Neuroscience🔔doi.org/10.1162/IMAG.a.1338
September 1, 2026 at 2:21 PM
Reposted by Ezra Winter-Nelson
Humans live many more years than mice, but our brain networks are aging much faster.

Brain network decline follows a common trajectory across mouse and human adulthood, with features of network organization linked to more rapid decline.

www.pnas.org/doi/10.1073/...
April 2, 2026 at 3:32 PM
Reposted by Ezra Winter-Nelson
🎉Huge congratulations to McEwen fellow @ewinternelson.bsky.social and Dr. Gagan Wig of UT Dallas on their recent publication in PNAS on large-scale brain network decline across aging mice and humans and its translational relevance. Read the paper here:

shorturl.at/gjau5
Correspondence of large-scale functional brain network decline across aging mice and humans | PNAS
Human aging is marked by progressive reorganization of large-scale functional brain networks; these brain network changes have been linked to cogni...
shorturl.at
March 30, 2026 at 1:58 PM
The first part of my PhD research is out now in PNAS! See the thread below and stay tuned for my dissertation work, which builds on this cross-species model of brain network aging
Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely

New @pnas.org paper🧵

www.pnas.org/doi/10.1073/...
March 31, 2026 at 3:47 PM