Faraidoon Haghdoost (Big Head Pain)
@faradoost.bsky.social
MD, PhD, Research Fellow in Headache disorders, @georgeinstitute
, conjoint lecturer @unsw, Sydney, Australia. Social Media Editor
@cephalalgia.bsky.social, #BigHeadPain
, conjoint lecturer @unsw, Sydney, Australia. Social Media Editor
@cephalalgia.bsky.social, #BigHeadPain
Reposted by Faraidoon Haghdoost (Big Head Pain)
Adding some ALT text for the attached graphic, it poses the same question as is in the post re: CGRPs⬆️BP, with a screenshot of the journal article title page and Dr. Haghdoost's website (FaraidoonHaghdoost.com).
Do anti-CGRP migraine medications increase blood pressure?
We analysed FDA data from 20 RCTs and 18,886 participants.
Reassuringly, neither anti-CGRP monoclonal antibodies nor gepants were associated with significant increases in BP vs placebo.
journals.sagepub.com/doi/full/10....
#headache
We analysed FDA data from 20 RCTs and 18,886 participants.
Reassuringly, neither anti-CGRP monoclonal antibodies nor gepants were associated with significant increases in BP vs placebo.
journals.sagepub.com/doi/full/10....
#headache
August 15, 2026 at 12:52 AM
Adding some ALT text for the attached graphic, it poses the same question as is in the post re: CGRPs⬆️BP, with a screenshot of the journal article title page and Dr. Haghdoost's website (FaraidoonHaghdoost.com).
🧠 What symptoms of cluster headache tend to occur together?
Our new study showed:
🔗 Tearing ↔️ runny nose
🔗 Smaller pupil ↔️ runny nose, drooping eyelid & eye swelling
🔗 Neck pain ↔️ back-of-the-head pain
link.springer.com/article/10.1...
#clusterheadache #headache
Our new study showed:
🔗 Tearing ↔️ runny nose
🔗 Smaller pupil ↔️ runny nose, drooping eyelid & eye swelling
🔗 Neck pain ↔️ back-of-the-head pain
link.springer.com/article/10.1...
#clusterheadache #headache
August 15, 2026 at 12:59 AM
🧠 What symptoms of cluster headache tend to occur together?
Our new study showed:
🔗 Tearing ↔️ runny nose
🔗 Smaller pupil ↔️ runny nose, drooping eyelid & eye swelling
🔗 Neck pain ↔️ back-of-the-head pain
link.springer.com/article/10.1...
#clusterheadache #headache
Our new study showed:
🔗 Tearing ↔️ runny nose
🔗 Smaller pupil ↔️ runny nose, drooping eyelid & eye swelling
🔗 Neck pain ↔️ back-of-the-head pain
link.springer.com/article/10.1...
#clusterheadache #headache
Do anti-CGRP migraine medications increase blood pressure?
We analysed FDA data from 20 RCTs and 18,886 participants.
Reassuringly, neither anti-CGRP monoclonal antibodies nor gepants were associated with significant increases in BP vs placebo.
journals.sagepub.com/doi/full/10....
#headache
We analysed FDA data from 20 RCTs and 18,886 participants.
Reassuringly, neither anti-CGRP monoclonal antibodies nor gepants were associated with significant increases in BP vs placebo.
journals.sagepub.com/doi/full/10....
#headache
August 15, 2026 at 12:42 AM
Do anti-CGRP migraine medications increase blood pressure?
We analysed FDA data from 20 RCTs and 18,886 participants.
Reassuringly, neither anti-CGRP monoclonal antibodies nor gepants were associated with significant increases in BP vs placebo.
journals.sagepub.com/doi/full/10....
#headache
We analysed FDA data from 20 RCTs and 18,886 participants.
Reassuringly, neither anti-CGRP monoclonal antibodies nor gepants were associated with significant increases in BP vs placebo.
journals.sagepub.com/doi/full/10....
#headache
199 randomised trials. 47,420 participants. One of the largest network meta-analyses of preventive treatments for migraine.
We showed beta-blockers and CGRP-targeted therapies have the most favourable balance of effectiveness and tolerability
ebm.bmj.com/content/earl...
@georgeinstitute.bsky.social
We showed beta-blockers and CGRP-targeted therapies have the most favourable balance of effectiveness and tolerability
ebm.bmj.com/content/earl...
@georgeinstitute.bsky.social
June 5, 2026 at 12:33 AM
199 randomised trials. 47,420 participants. One of the largest network meta-analyses of preventive treatments for migraine.
We showed beta-blockers and CGRP-targeted therapies have the most favourable balance of effectiveness and tolerability
ebm.bmj.com/content/earl...
@georgeinstitute.bsky.social
We showed beta-blockers and CGRP-targeted therapies have the most favourable balance of effectiveness and tolerability
ebm.bmj.com/content/earl...
@georgeinstitute.bsky.social
Migraine in pregnancy? Begin with lifestyle: hydration, sleep & stress relief. Use paracetamol; NSAIDs only mid-pregnancy. Prevent with beta-blockers or amitriptyline; avoid other meds. Details: journals.sagepub.com/doi/10.1177/... Prepared with AI assistance
April 28, 2026 at 2:43 AM
Migraine in pregnancy? Begin with lifestyle: hydration, sleep & stress relief. Use paracetamol; NSAIDs only mid-pregnancy. Prevent with beta-blockers or amitriptyline; avoid other meds. Details: journals.sagepub.com/doi/10.1177/... Prepared with AI assistance
Reposted by Faraidoon Haghdoost (Big Head Pain)
Congrats @faradoost.bsky.social on receiving the go-ahead for the first NHMRC/MRFF-funded study on headache disorders in over 20 years.
The study will investigate the use of psilocybin for the treatment of cluster headache, a severe condition with still no effective treatments: bit.ly/42LQO8C
The study will investigate the use of psilocybin for the treatment of cluster headache, a severe condition with still no effective treatments: bit.ly/42LQO8C
Hope for cluster headache community as psilocybin trial funded
One of the world’s first clinical trials into the potential for psychedelic compound psilocybin to prevent disabling cluster headache will be funded...
bit.ly
September 30, 2025 at 7:11 AM
Congrats @faradoost.bsky.social on receiving the go-ahead for the first NHMRC/MRFF-funded study on headache disorders in over 20 years.
The study will investigate the use of psilocybin for the treatment of cluster headache, a severe condition with still no effective treatments: bit.ly/42LQO8C
The study will investigate the use of psilocybin for the treatment of cluster headache, a severe condition with still no effective treatments: bit.ly/42LQO8C
I’m very excited to share some big news 🎉
Our team has received funding from the Australian MRFF to launch The Psilocybin Efficacy and Acceptability on Cluster headache Episodes (PEACE) Trial.
Read: www.georgeinstitute.org/news-and-med...
@georgeinstitute.bsky.social @clusterbusters.bsky.social
Our team has received funding from the Australian MRFF to launch The Psilocybin Efficacy and Acceptability on Cluster headache Episodes (PEACE) Trial.
Read: www.georgeinstitute.org/news-and-med...
@georgeinstitute.bsky.social @clusterbusters.bsky.social
September 30, 2025 at 6:25 AM
I’m very excited to share some big news 🎉
Our team has received funding from the Australian MRFF to launch The Psilocybin Efficacy and Acceptability on Cluster headache Episodes (PEACE) Trial.
Read: www.georgeinstitute.org/news-and-med...
@georgeinstitute.bsky.social @clusterbusters.bsky.social
Our team has received funding from the Australian MRFF to launch The Psilocybin Efficacy and Acceptability on Cluster headache Episodes (PEACE) Trial.
Read: www.georgeinstitute.org/news-and-med...
@georgeinstitute.bsky.social @clusterbusters.bsky.social
Grateful to connect with great mentors and clinicians at IHC2025 🌟 Richard Lipton (USA), Peter Goadsby (UK), Ishaq Abu-Arafeh (UK), and Mona Nada (Egypt). I am learning so much from them and truly enjoy every conversation 🤝🌍 #ihc2025 #cephalalgia2025
September 18, 2025 at 8:17 AM
Grateful to connect with great mentors and clinicians at IHC2025 🌟 Richard Lipton (USA), Peter Goadsby (UK), Ishaq Abu-Arafeh (UK), and Mona Nada (Egypt). I am learning so much from them and truly enjoy every conversation 🤝🌍 #ihc2025 #cephalalgia2025
Posters I presented at IHC2025 🧠✨ For two of them, my students couldn’t attend due to visa issues, so I presented on their behalf — they were truly missed! 🌍 #ihc2025 #cephalalgia2025
September 16, 2025 at 3:40 AM
Posters I presented at IHC2025 🧠✨ For two of them, my students couldn’t attend due to visa issues, so I presented on their behalf — they were truly missed! 🌍 #ihc2025 #cephalalgia2025
With the Australian and New Zealand Headache Society team at the conference 🧠 Always learning a lot from them and enjoying every opportunity to connect! #ihc2025 #cephalalgia2025
September 16, 2025 at 2:22 AM
With the Australian and New Zealand Headache Society team at the conference 🧠 Always learning a lot from them and enjoying every opportunity to connect! #ihc2025 #cephalalgia2025
Very proud of my students — Pratheeshan (UK), Omid (Iran), and Sobin (Nepal). Here we are by their poster, with Omid presenting during IHC2025 👏🌍 #ihc2025 #cephalalgia2025
September 15, 2025 at 8:03 PM
Very proud of my students — Pratheeshan (UK), Omid (Iran), and Sobin (Nepal). Here we are by their poster, with Omid presenting during IHC2025 👏🌍 #ihc2025 #cephalalgia2025
IHS Soccer Match ⚽🌍 Americas vs World — and I won… because I played for both teams! 😄🏆 #ihc2025 #cephalalgia2025
September 14, 2025 at 12:10 PM
IHS Soccer Match ⚽🌍 Americas vs World — and I won… because I played for both teams! 😄🏆 #ihc2025 #cephalalgia2025
With the Iranian team at IHC2025 — always one of the best parts of the conference for me. Especially special to meet Prof. Togha, one of the most wonderful people I’ve ever met 🌟 #ihc2025 #cephalalgia2025
September 14, 2025 at 12:05 PM
With the Iranian team at IHC2025 — always one of the best parts of the conference for me. Especially special to meet Prof. Togha, one of the most wonderful people I’ve ever met 🌟 #ihc2025 #cephalalgia2025
With Prof. Jes Olesen — the father of the International Headache Classification, who has identified key signalling mechanisms in migraine that paved the way for new drug targets and approved treatments 🙌🧠 #ihc2025 #cephalalgia2025
brainprize.org/winners/migra...
brainprize.org/winners/migra...
September 12, 2025 at 1:00 PM
With Prof. Jes Olesen — the father of the International Headache Classification, who has identified key signalling mechanisms in migraine that paved the way for new drug targets and approved treatments 🙌🧠 #ihc2025 #cephalalgia2025
brainprize.org/winners/migra...
brainprize.org/winners/migra...
Great to meet friends and colleagues from Iran at this international conference 🌍🤝 #ihc2025 #cephalalgia2025
September 11, 2025 at 7:00 PM
Great to meet friends and colleagues from Iran at this international conference 🌍🤝 #ihc2025 #cephalalgia2025
Three legends sharing powerful insights on designing clinical trials in headache research 👏🧠 #ihc2025 #cephalalgia2025
September 11, 2025 at 1:25 PM
Three legends sharing powerful insights on designing clinical trials in headache research 👏🧠 #ihc2025 #cephalalgia2025
With two amazing people and impactful scientists in the field of headache disorders — Aynur Özge and Debbie Hay 🌟🧠 #ihc2025 #cephalalgia2025
September 11, 2025 at 1:05 PM
With two amazing people and impactful scientists in the field of headache disorders — Aynur Özge and Debbie Hay 🌟🧠 #ihc2025 #cephalalgia2025
Finally meeting Nina in person after working together for so long 🤗 Also wonderful to catch up with Jr-Wei again! #ihc2025 #cephalalgia2025
September 11, 2025 at 1:00 PM
Finally meeting Nina in person after working together for so long 🤗 Also wonderful to catch up with Jr-Wei again! #ihc2025 #cephalalgia2025
A powerful call to action for migraine trials: moving beyond placebo to strategies that truly change the course of disease. Faster, smarter, and more effective approaches to improve migraine management. 💡 #ihc2025 #cephalalgia2025
September 10, 2025 at 10:45 PM
A powerful call to action for migraine trials: moving beyond placebo to strategies that truly change the course of disease. Faster, smarter, and more effective approaches to improve migraine management. 💡 #ihc2025 #cephalalgia2025
Wonderful to meet colleagues and mentors from Iran and Egypt 🌍✨ #ihc2025 #cephalalgia2025
September 10, 2025 at 7:37 PM
Wonderful to meet colleagues and mentors from Iran and Egypt 🌍✨ #ihc2025 #cephalalgia2025
From Norway to Nepal — what a global family! 🌍✨ So great catching up with colleagues and friends at #ihc2025 #cephalalgia2025
September 10, 2025 at 7:00 PM
From Norway to Nepal — what a global family! 🌍✨ So great catching up with colleagues and friends at #ihc2025 #cephalalgia2025
Excited about the event ahead! 🌟 #ihc2025 #cephalalgia2025
September 10, 2025 at 12:51 PM
Excited about the event ahead! 🌟 #ihc2025 #cephalalgia2025
Let’s get the conference started! 🚀✨ #ihc2025 #cephalalgia2025
September 10, 2025 at 12:26 PM
Let’s get the conference started! 🚀✨ #ihc2025 #cephalalgia2025
Enjoying fresh coconut in Ibirapuera Park with colleagues the day before the conference 🌴🥥☀️ #ihc2025 #cephalalgia2025
September 9, 2025 at 3:34 PM
Enjoying fresh coconut in Ibirapuera Park with colleagues the day before the conference 🌴🥥☀️ #ihc2025 #cephalalgia2025
Just landed in São Paulo and already bumped into colleagues at the airport — what a small world! ✈️🤝 #ihc2025 #cephalalgia2025”
September 9, 2025 at 2:07 AM
Just landed in São Paulo and already bumped into colleagues at the airport — what a small world! ✈️🤝 #ihc2025 #cephalalgia2025”