hraoh.bsky.social
hraoh.bsky.social
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Linker free PROTACs efficiently induce target degradation / TPD rdcu.be/enwPl
Linker-free PROTACs efficiently induce the degradation of oncoproteins
Nature Communications - Linkers are traditionally seen as important for PROTAC activity. Here, the authors demonstrate that linker-free PROTACs can outperform traditional designs, marking a...
rdcu.be
May 25, 2025 at 2:28 AM
Reposted by hraoh.bsky.social
Linker-free PROTACs efficiently induce the degradation of oncoproteins | #TPD #protac
Linker-free PROTACs efficiently induce the degradation of oncoproteins - Nature Communications
Linkers are traditionally seen as important for PROTAC activity. Here, the authors demonstrate that linker-free PROTACs can outperform traditional designs, marking a paradigm shift in PROTAC developme...
www.nature.com
May 23, 2025 at 10:12 PM
Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC) pubs.acs.org/doi/10.1021/...
pubs.acs.org
November 15, 2024 at 12:49 PM