hsm142.bsky.social
@hsm142.bsky.social
Biology, genetics
Reposted
Thanks to new funding from @wellcometrust.bsky.social we will soon be advertising two postdoc positions! Interested? Please get in touch in the first instance and I'll provide more info on the projects. You can also learn more on our lab website www.theradlab.co.uk
#immunosky 🧪
The RAD fungal infection lab
www.theradlab.co.uk
June 23, 2025 at 1:24 PM
Reposted
🔥 Super happy with this new paper led by @sbradshaw26.bsky.social and collab with @andrewpom.bsky.social 🔥 published in Proc B today

We find that meiotic drive impacts metabolic phenotypes: mito function, metabolic rate and food consumption

royalsocietypublishing.org/doi/epdf/10....
July 2, 2025 at 8:03 AM
Reposted
Genome Biology conference in Birmingham UK in September. Check out our great invited speakers! Lots of slots for talks selected from abstracts too! Please repost 😀
The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
June 25, 2025 at 3:41 PM
Reposted
New preprint! We have discovered that the splicing factor Sex lethal (Sxl - well known for its role in sex determination) binds to chromatin and regulates tRNA synthesis in neurons by interacting with RNA Pol III! Highlighting Sxl as a novel modulator of neuronal homeostasis. tinyurl.com/s44s2z95
Sex-lethal is recruited to chromatin to promote neuronal tRNA synthesis in males through RNA Polymerase III regulation
The RNA-binding protein Sex-lethal (Sxl) is classically known as a master regulator of sex determination and mRNA splicing in Drosophila melanogaster. However, this role is not conserved across specie...
tinyurl.com
April 26, 2025 at 9:36 AM
Reposted
Want to get paid while gaining valuable experience this summer? 🌟

Our research studentships are open for applications — but time is running out!
📅 Deadline: Friday 2 May

www.gen.cam.ac.uk/undergraduat...
April 28, 2025 at 8:55 AM
Reposted
1 week left to apply for this fully-funded PhD project combining microbiology, bioinformatics and C. elegans development. Please share with your students! @mmbdtp.bsky.social @biouea.bsky.social @earlhaminst.bsky.social @ueahealthsciences.bsky.social
April 7, 2025 at 10:30 AM
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Update on the future of FlyBase:

On 2/1/2029 FlyBase funding will come from the Alliance grant. By then, www.alliancegenome.org will access all FlyBase data. NIH has had a long term plan for a common MOD web site. We are formulating a comprehensive plan to transition FlyBase data to the Alliance.
Alliance of Genome Resources
www.alliancegenome.org
April 1, 2025 at 5:59 PM
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Hearing about some US universities advising their international scientists (green card holders & visa holders) not to leave the US for the time being for fear that re-entry will be non-trivial even with all the necessary documents in hand.

Is this happening at your institution?
March 19, 2025 at 10:36 PM
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Epic effort led by Tomo Ameku in the lab, with contributions from the labs of Nick Bellono, Vassilis Pachnis, @francoisleulier.bsky.social, @schwarzergnoto.bsky.social, @priscaliberali.bsky.social, ‪@coxlabkcl.bsky.social,‬ @priscaliberali.bsky.social and Maria Rodriguez-Colman
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:32 PM
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📣 We are advertising for a postdoc to join our team at the University of Edinburgh! Our lab studies gene regulatory mechanisms in development, and how genetic changes may impact these processes to alter development and shape human craniofacial form and function 🧬🧪
Postdoctoral Researcher
Our research is focused on understanding how genetic changes in the non-coding genome can impact gene regulatory mechanisms, alter developmental processes and ultimately affect human craniofacial shap...
elxw.fa.em3.oraclecloud.com
March 20, 2025 at 9:22 AM
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Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required.
Please Repost 🙏 thanks !
March 5, 2025 at 5:20 PM
Reposted
Multiple group leader positions in developmental biology in @ibdm.bsky.social Marseille, at an institute that produces some great work.
We Are Recruiting Group Leaders - IBDM | Institut de Biologie du Développement de Marseille
The Institut de Biologie du Développement de Marseille (IBDM) is inviting applications for group leader positions. We are seeking innovative researchers who aim to address fundamental questions in bio...
staging.ibdm.univ-amu.fr
March 4, 2025 at 10:15 AM
Reposted
Very happy to announce that our new paper on how asymmetric #microtubule nucleation from Golgi is required for #microtubule #polarity in #neurons has been published online in @currentbiology.bsky.social. An amazing effort from postdoc Akila Yagoubat. authors.elsevier.com/a/1kiDc3QW8S...
March 3, 2025 at 4:55 PM
Reposted
In drosophila, by manipulating sets of surface proteins, you can re-engineer connectivity of olfactory neurons and generate a new neuron type that alters courtship behavior. Impressive work from the Luo lab.
doi.org/10.1101/2025...
Rewiring an olfactory circuit by altering the combinatorial code of cell-surface proteins
Proper brain function requires the precise assembly of neural circuits during development. Despite the identification of many cell-surface proteins (CSPs) that help guide axons to their targets, it re...
doi.org
March 3, 2025 at 5:36 AM
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Less than a week left to apply to the open post doc position in our lab. Join us in beautiful Gothenburg to work on an exciting project!
www.nature.com/naturecareer...
Postdoc on Mitochondrial Biogenesis and Quality Control - Gothenburg (Stad), Västra Götaland (SE) job with University of Gothenburg | 12835658
Investigating the molecular connectivity of mitochondrial gene expression, protein biogenesis and quality control Background: Mitochondria convert ...
www.nature.com
March 3, 2025 at 11:44 AM
Reposted
Our next featured #EDRC2025 invited speaker is Romain Levayer @levayerr.bsky.social @pasteur.fr a cell and developmental biologist who has been working for many years on the emergence of complexity and the plasticity of developing tissues using #Drosophila as a model system
March 3, 2025 at 8:45 AM
Reposted
Is there more to defining the eve stripes in the Drosophila embryo than just transcriptional regulation? We provide evidence that spatially regulated mRNA decay is also important.
Nice new paper from Jennifer Love and @hilaryashe.bsky.social lab members shows how mRNA decay is spatially and temporally regulated, ramping up at the edges of stripes in early drosophila embryos, with mRNAs increasingly localising to P-bodies for degradation www.biorxiv.org/content/10.1...
www.biorxiv.org
February 24, 2025 at 9:29 PM
Reposted
Hansong Ma and coworkers identify POLDIP2 as a novel mitochondrial exonuclease interacting with CLPX protease and promoting elimination of paternal mtDNA during Drosophila spermatogenesis
www.embopress.org/doi/full/10....
February 14, 2025 at 3:54 PM
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Development folks: the next Northern England Developmental Biology @bsdb.bsky.social @biologists.bsky.social meeting will take place on the 10th of July in Sheffield. Great speaker line-up, cheap registration fee and plenty of slots for ECR talks. Registration deadline=31/5, see poster for details
February 20, 2025 at 1:53 PM
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Open for another week, if you're interested in our Department for setting up your group. Happy to answer queries.
Come join us as a group leader:
www.jobs.cam.ac.uk/job/49356/
Happy to answer queries.
February 21, 2025 at 3:07 PM
Reposted
Hello everyone on Bluesky! 🧪

We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond.

Read more: www.embo.org/about-embo/m...
February 12, 2025 at 12:56 PM
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Jeff Lee et al paper from my lab is out now
www.science.org/doi/10.1126/...

I am very grateful to Jeff, Nile's and Tamsin for all the hard work on this tour de force paper.
Jeff deserves more credit than me for masterminding it and the outstanding data analysis: 2 RBPs over 3 developmental times.
Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators of Drosophila brain development
RNA binding protein combinations control neuronal identity through a network of temporal regulators.
www.science.org
February 12, 2025 at 11:19 PM
Reposted
Evolution of Wolbachia male-killing mechanism within a host species

"In vitro and in vivo data demonstrated that wBol1Y (Wolbachia) feminized splicing and expression of lepidopteran sex determination pathway genes."

www.biorxiv.org/content/10.1...
Evolution of Wolbachia male-killing mechanism within a host species
Male-killing bacterial symbionts, prevalent in arthropods, skew population sex ratios by selectively killing male progeny, profoundly impacting ecology and evolution of their hosts. Male-killing is a ...
www.biorxiv.org
February 13, 2025 at 4:19 PM
Reposted
Come and joint us at @mrclmb.bsky.social ! We have an opening for a new group leader in the Structural Studies Division. We are very interactive and collaborative with amazing facilities and generous core funding. Get in touch with myself or @sjorsscheres.bsky.social if you have any questions.
Join our Structural Studies Division, leading a research group developing computational methods to address questions in molecular & cellular biology!
You will be supported by core funding, excellent facilities & enthusiastic colleagues.
Apply by 18 MAR
www.nature.com/naturecareer...
February 7, 2025 at 3:03 PM
Reposted
Looking for an enthusiastic post-doc to investigate how experience shapes the brain. Drosophila neurogenetics, molecular and cellular mechanisms, imaging, optogenetics, neural circuits and behaviour will be used. At University of Birmingham campus, UK. Application deadline 19 March.
Pls RT.
February 10, 2025 at 8:58 AM