Laboratory Investigation
@labinvest.bsky.social
Official Journal of the United States and Canadian Academy of Pathology. LI offers prompt publication of high-quality original research that advances the understanding and classification of human disease.
www.laboratoryinvestigation.com
www.laboratoryinvestigation.com
New from Laboratory Investigation 🔬 | Integrating molecular, histopathologic, and spatial transcriptomic profiling reveals shared pathogenic features of lymphatic malformations and highlights NFATC1 activation in lymphatic endothelial cells.
🔗 Hirose et al. Read the article buff.ly/NgRf8ra
🔗 Hirose et al. Read the article buff.ly/NgRf8ra
September 24, 2026 at 1:30 PM
New from Laboratory Investigation 🔬 | Integrating molecular, histopathologic, and spatial transcriptomic profiling reveals shared pathogenic features of lymphatic malformations and highlights NFATC1 activation in lymphatic endothelial cells.
🔗 Hirose et al. Read the article buff.ly/NgRf8ra
🔗 Hirose et al. Read the article buff.ly/NgRf8ra
New from Laboratory Investigation 🔬 | Optimizing DNA extraction from archival prostate biopsies to maximize DNA yield from limited tumor samples for molecular testing.
🔗 Amaral et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Amaral et al. Read the article: www.laboratoryinvestigation.org/article/S002...
Optimizing DNA Extraction from Archival Prostate Biopsy Samples
In this paper, we compare the performance of three distinct nucleic acid extraction protocols in a large population-based prostate cancer cohort, aiming to optimize DNA yield from limited tumor…
www.laboratoryinvestigation.org
September 22, 2026 at 3:18 PM
New from Laboratory Investigation 🔬 | Optimizing DNA extraction from archival prostate biopsies to maximize DNA yield from limited tumor samples for molecular testing.
🔗 Amaral et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Amaral et al. Read the article: www.laboratoryinvestigation.org/article/S002...
New from Laboratory Investigation 🔬 | Identifying two novel compound heterozygous ADAMTS17 variants associated with Weill–Marchesani syndrome 4, including a deep intronic variant shown to disrupt normal splicing.
🔗 Ku et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Ku et al. Read the article: www.laboratoryinvestigation.org/article/S002...
September 18, 2026 at 11:16 AM
New from Laboratory Investigation 🔬 | Identifying two novel compound heterozygous ADAMTS17 variants associated with Weill–Marchesani syndrome 4, including a deep intronic variant shown to disrupt normal splicing.
🔗 Ku et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Ku et al. Read the article: www.laboratoryinvestigation.org/article/S002...
New from Laboratory Investigation 🔬 | Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases @Renalpathsoc
🔗 Gaut et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Gaut et al. Read the article: www.laboratoryinvestigation.org/article/S002...
Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases
This study aims to examine current global renal biopsy pre-analytic and analytic variability according to country income status. Technology access, pathologist workforce, and case volume variations…
www.laboratoryinvestigation.org
August 26, 2026 at 5:56 PM
New from Laboratory Investigation 🔬 | Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases @Renalpathsoc
🔗 Gaut et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Gaut et al. Read the article: www.laboratoryinvestigation.org/article/S002...
New from Laboratory Investigation 🔬 | Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes @TingZhaoPathdoc
🔗 Zhao et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Zhao et al. Read the article: www.laboratoryinvestigation.org/article/S002...
Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes
Consensus molecular classes of urothelial carcinoma (UC) include basal/squamous (Ba/Sq), luminal papillary (LumP), luminal nonspecified (LumNS), luminal unstable (LumU), stroma-rich, and…
www.laboratoryinvestigation.org
August 26, 2026 at 5:56 PM
New from Laboratory Investigation 🔬 | Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes @TingZhaoPathdoc
🔗 Zhao et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Zhao et al. Read the article: www.laboratoryinvestigation.org/article/S002...
New from Laboratory Investigation 🔬 | Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
🔗 Chung et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Chung et al. Read the article: www.laboratoryinvestigation.org/article/S002...
Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
Accurate prediction of lymph node metastasis (LNM) remains challenging in early gastric cancer (EGC), particularly when determining the need for additional surgery after endoscopic resection. We…
www.laboratoryinvestigation.org
August 26, 2026 at 5:55 PM
New from Laboratory Investigation 🔬 | Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
🔗 Chung et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Chung et al. Read the article: www.laboratoryinvestigation.org/article/S002...
New from Laboratory Investigation 🔬 | Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases @Renalpathsoc
🔗 Gaut et al. Read the article: www.sciencedirect.com/science/arti...
🔗 Gaut et al. Read the article: www.sciencedirect.com/science/arti...
https://www.sciencedirect.com/science/article/pii/S0023683726000899
www.sciencedirect.com
August 26, 2026 at 5:17 PM
New from Laboratory Investigation 🔬 | Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases @Renalpathsoc
🔗 Gaut et al. Read the article: www.sciencedirect.com/science/arti...
🔗 Gaut et al. Read the article: www.sciencedirect.com/science/arti...
New from Laboratory Investigation 🔬 | Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes @TingZhaoPathdoc
🔗 Zhao et al. Read the article: www.sciencedirect.com/science/arti...
🔗 Zhao et al. Read the article: www.sciencedirect.com/science/arti...
https://www.sciencedirect.com/science/article/pii/S0023683726000905
www.sciencedirect.com
August 26, 2026 at 5:13 PM
New from Laboratory Investigation 🔬 | Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes @TingZhaoPathdoc
🔗 Zhao et al. Read the article: www.sciencedirect.com/science/arti...
🔗 Zhao et al. Read the article: www.sciencedirect.com/science/arti...
New from Laboratory Investigation 🔬 | Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
🔗 Chung et al. Read the article: www.sciencedirect.com/science/arti...
🔗 Chung et al. Read the article: www.sciencedirect.com/science/arti...
August 26, 2026 at 5:09 PM
New from Laboratory Investigation 🔬 | Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
🔗 Chung et al. Read the article: www.sciencedirect.com/science/arti...
🔗 Chung et al. Read the article: www.sciencedirect.com/science/arti...
New from Laboratory Investigation 🔬 | Intratumoral macrophage subsets and CD8 are associated with favorable outcomes during PD-1–based immunotherapy #openaccess
🔗 Ohkuma et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Ohkuma et al. Read the article: www.laboratoryinvestigation.org/article/S002...
Association of Intratumoral Macrophage Subsets with Treatment Outcomes in Patients with Stage IV Solid Tumors
To assess whether pretreatment intratumoral macrophage-associated and T-cell marker-positive areas are associated with treatment outcomes in patients with stage IV solid tumors receiving programmed…
www.laboratoryinvestigation.org
August 13, 2026 at 3:07 AM
New from Laboratory Investigation 🔬 | Intratumoral macrophage subsets and CD8 are associated with favorable outcomes during PD-1–based immunotherapy #openaccess
🔗 Ohkuma et al. Read the article: www.laboratoryinvestigation.org/article/S002...
🔗 Ohkuma et al. Read the article: www.laboratoryinvestigation.org/article/S002...
THE #USCAP2025 EXHIBIT HALL IS OPEN!
Make sure to stop by the USCAP booth in the center of the Exhibit Hall to say hi to your FAVORITE #ModernPathology and #LaboratoryInvestigation JOURNAL MANAGERS!
#Pathology
Make sure to stop by the USCAP booth in the center of the Exhibit Hall to say hi to your FAVORITE #ModernPathology and #LaboratoryInvestigation JOURNAL MANAGERS!
#Pathology
March 24, 2025 at 4:26 PM
THE #USCAP2025 EXHIBIT HALL IS OPEN!
Make sure to stop by the USCAP booth in the center of the Exhibit Hall to say hi to your FAVORITE #ModernPathology and #LaboratoryInvestigation JOURNAL MANAGERS!
#Pathology
Make sure to stop by the USCAP booth in the center of the Exhibit Hall to say hi to your FAVORITE #ModernPathology and #LaboratoryInvestigation JOURNAL MANAGERS!
#Pathology
Laboratory Investigation is an international journal owned by the United States and Canadian Academy of #Pathology. Laboratory Investigation offers prompt publication of high-quality original research that advances the understanding and classification of #humandisease.
WE ARE AT #USCAP2025!
WE ARE AT #USCAP2025!
March 23, 2025 at 3:16 PM
Laboratory Investigation is an international journal owned by the United States and Canadian Academy of #Pathology. Laboratory Investigation offers prompt publication of high-quality original research that advances the understanding and classification of #humandisease.
WE ARE AT #USCAP2025!
WE ARE AT #USCAP2025!