Marielle Saclier
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mariellesaclier.bsky.social
Marielle Saclier
@mariellesaclier.bsky.social
PhD // Postdoc in HanLi lab Institut @pasteur.fr // Macrophage - Tissue Regeneration - Cellular Interaction & Communication // She/Her
I could not say better.
Thanks to SPAIS and the Postdoc Office at @pasteur.fr, to our supervisors Tim Wai and @hanli-pasteur.bsky.social @devstempasteur.bsky.social. And of course to @juandihc.bsky.social for this fantastic adventure!
Take home message: exercise, your futur old body will thank you!
Great news before the summer break! Our review on the Impact of Ageing on Skeletal Muscle is out in the Journal of Cellular Physiology. @mariellesaclier.bsky.social and I are thrilled to share our perspective on mitochondrial dysregulation, systemic communication, and exercise in muscle ageing
July 29, 2026 at 1:40 PM
Glad to have contributed to that work !
Senescence links regeneration to oncogenic vulnerability.
Our latest work demonstrates that #senescence drives #postpartum mammary involution while simultaneously creating a transient microenvironment permissive for tumor initiation #breastcancer. @institutpasteur.bsky.social
More details 👇
Online now! ✨Chiche, Djoual, Charifou et al identify a dual role for senescence in postpartum tissue remodelling: senescent cells drive mammary gland involution, yet predispose to postpartum tumor initiation @hanli-pasteur.bsky.social @pasteur.fr
February 21, 2026 at 3:17 PM
Postdoc position in the lab.
Great team and place to work with!
Postdoc opportunity!

Curious to know how senescence contributes to “cancers are wounds that never heal”?

Join us to study how senescence as a double-edged regulator of the microenvironment, linking regeneration and tumorigenesis.

More infor: research.pasteur.fr/en/job/job-p...
Job: postdoc position in cellular senescence, tissue repair and tumorigenesis - Research
Host Lab our lab (https://research.pasteur.fr/en/team/cellular-plasticity-in-age-related-pathologies/ ) explores how cellular senescence orchestrates tissue repair and regeneration. We focus on how se...
research.pasteur.fr
October 1, 2025 at 6:15 AM
Reposted by Marielle Saclier
Excited to share that the preprint of my Ph.D. work is now available! 🎉 Huge thanks to my amazing co-authors for their support and collaboration: @gaellel.bsky.social, H. Varet, V. Laville, J. Fernandes, @tajbakhshlab.bsky.social, @brendan-evano.bsky.social.
@devstempasteur.bsky.social @pasteur.fr
Impaired stem cell migration and divisions in Duchenne Muscular Dystrophy revealed by live imaging
Dysregulation of stem cell properties is a hallmark of many pathologies, but the dynamic behaviour of stem cells in their microenvironment during disease progression remains poorly understood. Using t...
www.biorxiv.org
March 14, 2025 at 9:03 PM