Claudia Mauri
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maurilab.bsky.social
Claudia Mauri
@maurilab.bsky.social
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Reposted by Claudia Mauri
prelights.bsky.social
An immunosuppressive B cell subset has been identified in renal cell carcinoma.

Congrats to our new preLighter, Charis Qi, on her first #preLight, which talks about the #preprint by the @maurilab.bsky.social !
Tumor-infiltrating CD27-IgD- regulatory B cells suppress cytotoxic CD8+T cell responses in renal cell carcinoma - preLights
An Immunosuppressive B Cell Subset Is Identified in Renal Cell Carcinoma.
prelights.biologists.com
August 12, 2025 at 1:09 PM
Reposted by Claudia Mauri
cp-immunity.bsky.social
More TOR: The expanding role of mTOR in regulating immune responses
The mammalian/mechanistic target of rapamycin (mTOR) signaling pathway integrates critical environmental and metabolic cues to regulate immune cell activation, differentiation, and function. Patel and Powell provide an updated comprehensive review of our current understanding of mTOR’s evolutionarily conserved role in immune cell biology.
dlvr.it
July 9, 2025 at 7:56 PM
Reposted by Claudia Mauri
cp-immunity.bsky.social
Online now: B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8+ T cell function
B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8+ T cell function
Liver regeneration (LR) is essential for recovery from acute trauma, cancer surgery, or transplantation. Fazel Modares et al. find that mouse LR after injury requires ChAT+ B cells synthesizing acetylcholine (ACh) and Kupffer cells and hepatic CD8+ T cells expressing α7 nicotinic ACh receptor (Chrna7). ChAT+ B cells drive Kupffer cell IL-6 secretion and reduce CD8+ T cell IFNγ.
dlvr.it
April 25, 2025 at 7:55 PM