M. Esther Gallardo
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mesthergallardo.bsky.social
M. Esther Gallardo
@mesthergallardo.bsky.social
46 followers 74 following 5 posts
Head of the Translational Research with iPS Cells Group. Hospital 12 de Octubre Research Institute, i+12. Madrid, Spain. Focus on: rare diseases
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mesthergallardo.bsky.social
Gran labor la que realiza ONCE, @ONCE_oficial y la Fundación ONCE baja vision #Bajavision con las personas ciegas o con baja visión 👇
December 5, 2025 at 6:39 PM
mesthergallardo.bsky.social
Celebrando la semana de la Ciencia e Innovación ✨️😊
November 4, 2025 at 9:28 PM
mesthergallardo.bsky.social
Happy to share our latest open access paper "3D Printing of Chitosan Scaffolds and Films with Varying Roughness for Cultivation of Human Retinal Progenitor Cells" | ACS Omega pubs.acs.org/doi/10.1021/...
A great collaboration between RISE PFI, imas12 and UCM ✨️👌
3D Printing of Chitosan Scaffolds and Films with Varying Roughness for Cultivation of Human Retinal Progenitor Cells
Chitosan was used for three-dimensional (3D) printing of films and well-resolved scaffolds. Three different molecular weights with a comparable degree of de-N-acetylation were studied for 3D printing;...
pubs.acs.org
September 30, 2025 at 9:51 PM
mesthergallardo.bsky.social
On monday 29th, was the closing meeting of the bioMAT4EYE project a multidisciplinary European initiative to develop new biomaterials for human induced pluripotent stem cells differentiation into retinal ganglion cells. Thanks to all consortium members, funders, and the M-ERA.NET initiative.
September 30, 2025 at 8:32 PM
Reposted by M. Esther Gallardo
responsiblesci.bsky.social
Science4Peace Seminar: The Responsibility of Scientists 🧪🕊️

Join Dr Philip Webber for a discussion on ethics in science, and the responsibilities of scientists from the Manhattan Project to modern WMDs.

📅 Wednesday 16th July, 2025 | 🕔 5pm CEST

us02web.zoom.us/meeting/regi...
Welcome! You are invited to join a meeting: S4P seminar: The responsibility of scientists by Dr Philip Webber. After registering, you will receive a confirmation email about joining the meeting.
Welcome! You are invited to join a meeting: S4P seminar: The responsibility of scientists by Dr Philip Webber. After registering, you will receive a confirmation email about joining the meeting.
us02web.zoom.us
July 15, 2025 at 7:21 AM
Reposted by M. Esther Gallardo
elife.bsky.social
👁️ Rod photoreceptors (your eye's light sensors) need more than sugar to survive.

A new study shows they rely on glutamine to stay healthy. This Insight Article explains the research and how this opens new doors for therapies to slow retinal degeneration.
buff.ly/vAHuvsF
Representative retinal sections from WT and cKO animals
May 30, 2025 at 8:02 PM
Reposted by M. Esther Gallardo
isscr.org
Be inspired at the ISSCR 2025 Annual Meeting! Join us in Hong Kong from 11-14 June and expand your horizons by bringing new tools, ideas, and technology back to your lab to use in your own research. 👉 www.isscr2025.org
May 29, 2025 at 8:56 PM
Reposted by M. Esther Gallardo
matthewcollins.bsky.social
🧵 Thread: 1️⃣ Fascinating paper by Stewart et al. shows robust method for sex determination using peptides in tooth enamel.

Great potential for #archaeology with fragmentary remains where DNA is degraded. #palaeoproteomics #ZooMS #teammasspec
figshare.com/s/a861c0d74d...
Diagram illustrating sex determination using amelogenin proteins in tooth enamel. The top shows X and Y chromosomally encoded protein isoforms (AMELX in blue, AMELY in red) with their amino acid sequences highlighted. The middle section displays amelogenin's structural progression from protein to nanospheres to matrix to enamel rods, alongside images of developing tooth structure with labeled components (ameloblasts, enamel, dentin, odontoblasts, pulp). The bottom shows Raman spectroscopy setup with IR laser and detector analyzing a tooth, demonstrating how incident light produces both Rayleigh scattering and Raman scattering from molecular vibrations, resulting in sex-specific spectra shown in a graph (blue and red lines) with male and female symbols. Biological sex determination is essential for analyzing human skeletal remains in archaeology, anthropology, and forensic science. This study investigates whether Raman spectroscopy of intact human dental enamel can be used as a non-destructive method for sex estimation. Orthogonal partial least squares discriminant analysis (OPLS-DA) and logistic regression identified sex-specific spectral characteristics in 88 human teeth from 47 modern individuals (26 females, 21 males). The OPLS-DA model showed excellent performance, with R2Y(cum) = 0.943 and Q2Y(cum) = 0.895. Raman shift wavenumbers at 373, 1182, and 1600 cm−1 were identified as the most reliable discriminators and included in a final logistic regression model. This model achieved an area under the receiver operating characteristic curve (ROC-AUC) of 0.98, a sensitivity of 0.87, and a specificity of 0.94. Our results indicate that Raman spectroscopy can effectively differentiate male and female human dental enamel based on subtle differences in molecular composition—possibly linked to residual differences between AMELX and AMELY-derived proteins.
May 6, 2025 at 3:12 AM
Reposted by M. Esther Gallardo
lilyfoundation.bsky.social
Ahead of #RareDiseaseDay, please join us to educate and increase awareness about rare mitochondrial diseases

Getting mito in the public eye helps drive research, boost donations and improve clinical care for those affected

Please share to advance rare
www.thelilyfoundation.org.uk/affected-by-...
February 26, 2025 at 2:21 PM
mesthergallardo.bsky.social
www.comunidad.madrid/hospital/12o...
El Hospital público 12 de Octubre busca tratamiento para la pérdida de visión de pacientes con neuropatías ópticas a través de nanopartículas que transportan fármacos
El Hospital Universitario 12 de Octubre, centro público de la Comunidad de Madrid, busca, junto con la colaboración de la ONCE, un tratamiento innovador para la pérdida de visión en pacientes con atro...
www.comunidad.madrid
February 17, 2025 at 4:00 PM
Reposted by M. Esther Gallardo
diarionutricion.com
El modelo tridimensional escalable 'intestino en un chip' permite la visualización en tiempo real de interacciones de microbios intestinales y el intestino humano, lo que es de gran interés para la atención médica preventiva y la industria farmacéutica
Desarrollan un modelo de "microintestino" para estudiar la relación entre microbios intestinales y enfermedades humanas
El modelo tridimensional escalable 'intestino en un chip' permite la visualización en tiempo real de interacciones de microbios intestinales y el intestino humano, lo que es de gran interés ...
bit.ly
February 16, 2025 at 10:01 AM
Reposted by M. Esther Gallardo
imbavienna.bsky.social
SY-Stem 2025 Symposium: Registration deadline on February 15th!
SY-Stem - a symposium focusing on the next generation of stem cell researchers - is organized by IMBA and @impvienna.bsky.social.
Register online: bit.ly/4jekaDg
Check out the program: bit.ly/4jDioM6
February 5, 2025 at 10:20 AM
Reposted by M. Esther Gallardo
elspells13.bsky.social
Today is the first ever ADOA Awareness Day

Autosomal Dominant Optic Atrophy is a rare condition that causes progressive vision loss.

One of my very best friends in the world has this condition, and she is now registered blind.

There is currently no cure - research is ongoing.
ADOA Awareness Day Poster 23 November 2023 Blue graphics with the following stats: 1 out of 30.000 people are affected by ADOA Up to 45% of patients are considered legally blind Progressive vision loss: symptoms include blurry vision, reduced contrast, color blindness and central vision loss No cure: research into a cure is challenging due to the complexity of the condition, but is ongoing.
November 23, 2024 at 7:05 PM