Matt Decker
@mndecker.bsky.social
UCSF Peds Heme/Onc PGY6. Columbia MD/PhD '20. Leukemia biology and targeted therapy development. Minnesota sports fan, unfortunately. Opinions my own, etc.
Reposted by Matt Decker
Sean Trende’s piece on his son’s last day of school is full of joy and sadness and love and is well worth your time.
www.realclearpolitics.com/articles/202...
www.realclearpolitics.com/articles/202...
May 23, 2026 at 1:42 PM
Sean Trende’s piece on his son’s last day of school is full of joy and sadness and love and is well worth your time.
www.realclearpolitics.com/articles/202...
www.realclearpolitics.com/articles/202...
There's been a lot of (justifiable) excitement about the mRNA vaccine trial in pancreatic cancer, but this is arguably more impactful. The data will formally be presented at ASCO later this spring but the headline finding - doubling overall survival in metastatic pancreatic cancer - is gobsmacking.
The long-awaited results from the RASolute 302 trial have been read out. Spoiler alert: It’s good news.
https://cancerletter.com/clinical/20260417_2/
https://cancerletter.com/clinical/20260417_2/
Long-awaited results from first phase III trial of a RAS inhibitor in pancreatic cancer shows that daraxonrasib doubles median OS PanCAN’s Berkenblit: “It’s here. This is a tipping point, and...
The long-awaited results from the RASolute 302 trial—a phase III clinical trial evaluating daraxonrasib, a RAS inhibitor, for the treatment of patients with previously treated, metastatic pancreatic ductal adenocarcinoma—have been read out. To access this subscriber-only content please log in or subscribe.If your institution has a site license, log in with IP-login or register for […]
cancerletter.com
April 23, 2026 at 6:09 PM
There's been a lot of (justifiable) excitement about the mRNA vaccine trial in pancreatic cancer, but this is arguably more impactful. The data will formally be presented at ASCO later this spring but the headline finding - doubling overall survival in metastatic pancreatic cancer - is gobsmacking.
Reposted by Matt Decker
Two things can be true:
1. FDA’s handling of Moderna’s mRNA flu vaccine review raises process questions
2. The data themselves were underwhelming
Here's my take, finishing up with perhaps the biggest disappointment -- it's a hit on pandemic preparedness.
blogs.nejm.org/hiv-id-obser...
1. FDA’s handling of Moderna’s mRNA flu vaccine review raises process questions
2. The data themselves were underwhelming
Here's my take, finishing up with perhaps the biggest disappointment -- it's a hit on pandemic preparedness.
blogs.nejm.org/hiv-id-obser...
Two Things Can Be True: The FDA Process Was Inconsistent, and the mRNA Vaccine Data Were Disappointing
Share Tweet Pin Mail SMS Any time I write about vaccines, especially mRNA vaccines, things get dicey. Any negative comments might fuel attacks from ...
blogs.nejm.org
February 17, 2026 at 6:12 PM
Two things can be true:
1. FDA’s handling of Moderna’s mRNA flu vaccine review raises process questions
2. The data themselves were underwhelming
Here's my take, finishing up with perhaps the biggest disappointment -- it's a hit on pandemic preparedness.
blogs.nejm.org/hiv-id-obser...
1. FDA’s handling of Moderna’s mRNA flu vaccine review raises process questions
2. The data themselves were underwhelming
Here's my take, finishing up with perhaps the biggest disappointment -- it's a hit on pandemic preparedness.
blogs.nejm.org/hiv-id-obser...
Reposted by Matt Decker
A look across the vaccine regulatory landscape in the US. There's a lot going on, and very little of it should be cause for optimism:
The Disastrous US Vaccine Landscape
www.science.org
January 27, 2026 at 5:29 PM
A look across the vaccine regulatory landscape in the US. There's a lot going on, and very little of it should be cause for optimism:
Reposted by Matt Decker
A video of Alex Pretti reading out the final salute of an unnamed veteran he cared for until the end of his life in the ICU, posted to Facebook by his son.
January 25, 2026 at 1:18 AM
A video of Alex Pretti reading out the final salute of an unnamed veteran he cared for until the end of his life in the ICU, posted to Facebook by his son.
Vaccination efficacy and safety studies have some of the most robust and reproducible findings in all of medicine. It makes us oncologists look bad, honestly.
CDC has overhauled its website to assert that “the claim ‘vaccines do not cause autism’ is not an evidence-based claim”
November 20, 2025 at 2:46 AM
Vaccination efficacy and safety studies have some of the most robust and reproducible findings in all of medicine. It makes us oncologists look bad, honestly.
Reposted by Matt Decker
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration.
blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org/hiv-id-obser...
Tragic Childhood Death from Measles Reminds Us That Some Don't Understand Either the Medical Significance or the Human Heart
My ID colleague Dr. Adam Ratner, Chief of Pediatric ID at NYU Medical Center, just published an insightful and remarkably timely book called Booster Shots: The Urgent Lessons of Measles and the Uncer...
blogs.jwatch.org
February 27, 2025 at 9:14 PM
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration.
blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org/hiv-id-obser...
Reposted by Matt Decker
Here are the 25 institutions that receive the most NIH funding (98% of HHS is NIH). Basically, they're large schools with large hospitals. They receive 50% of all NIH funding.
Source: ncses.nsf.gov/surveys/fede... (table 26)
(Not going to do a whole thread but thought folks might be interested.)
Source: ncses.nsf.gov/surveys/fede... (table 26)
(Not going to do a whole thread but thought folks might be interested.)
February 8, 2025 at 3:20 PM
Here are the 25 institutions that receive the most NIH funding (98% of HHS is NIH). Basically, they're large schools with large hospitals. They receive 50% of all NIH funding.
Source: ncses.nsf.gov/surveys/fede... (table 26)
(Not going to do a whole thread but thought folks might be interested.)
Source: ncses.nsf.gov/surveys/fede... (table 26)
(Not going to do a whole thread but thought folks might be interested.)
Reposted by Matt Decker
Uh, this is a nuclear bomb on university budgets if I am reading it correctly. Mandating an indirect cost rate of 15% *overnight*?
February 7, 2025 at 10:56 PM
Uh, this is a nuclear bomb on university budgets if I am reading it correctly. Mandating an indirect cost rate of 15% *overnight*?