Somesh Sai
@saisomesh.bsky.social
Posdoctoral Researcher @ @mdc-berlin.bsky.social
Excited to finally share our latest work!
We show that increased β-cell workload drives adaptive state transitions, but chronic activation can promote maladaptive states linked to β-cell failure in T2D.
Huge thanks to @worthamlab.bsky.social and all co-authors for their guidance and collaboration.
We show that increased β-cell workload drives adaptive state transitions, but chronic activation can promote maladaptive states linked to β-cell failure in T2D.
Huge thanks to @worthamlab.bsky.social and all co-authors for their guidance and collaboration.
Excited to share our latest work on beta cell adaptation and failure during increased workload! We found that deletion of the chromatin modifier Lsd1 has differing effects on glycemia in insulin resistant and insulin sensitive models via regulation of beta cell states (1/3) tinyurl.com/yxackfce
May 19, 2026 at 8:26 AM
Excited to finally share our latest work!
We show that increased β-cell workload drives adaptive state transitions, but chronic activation can promote maladaptive states linked to β-cell failure in T2D.
Huge thanks to @worthamlab.bsky.social and all co-authors for their guidance and collaboration.
We show that increased β-cell workload drives adaptive state transitions, but chronic activation can promote maladaptive states linked to β-cell failure in T2D.
Huge thanks to @worthamlab.bsky.social and all co-authors for their guidance and collaboration.