Samuel Weisenthal
@samweisenthal.bsky.social
stats, data science, family medicine, commentary on language models
https://samuelweisenthal.github.io
https://samuelweisenthal.github.io
Pinned
arxiv.org
Constant sens/spec assumption (see Dawid 1976, Moons and Harrell 2003, Guggenmoos 2000) + pre-test probability scores (eg Wells’) = Information Mismatch
Preprint: arxiv.org/pdf/2503.15382
Preprint: arxiv.org/pdf/2503.15382
Reposted by Samuel Weisenthal
AI billionaire-funded Super PACs will spend millions in the home stretch of the midterms to crush the anti-data center revolt in battleground states.
And that's just a drop in the bucket compared to how much these oligarchs would rake in from the AI takeover.
And that's just a drop in the bucket compared to how much these oligarchs would rake in from the AI takeover.
September 4, 2026 at 7:30 PM
AI billionaire-funded Super PACs will spend millions in the home stretch of the midterms to crush the anti-data center revolt in battleground states.
And that's just a drop in the bucket compared to how much these oligarchs would rake in from the AI takeover.
And that's just a drop in the bucket compared to how much these oligarchs would rake in from the AI takeover.
Reposted by Samuel Weisenthal
So far the war in Iran has cost an estimated $5.5 billion.
That's roughly $1 billion per day.
$41,666,667 per hour.
$11,574 per second.
People do not want this.
They want a living wage. They want healthcare. They want to be able to afford a home. They want their basic needs met.
That's roughly $1 billion per day.
$41,666,667 per hour.
$11,574 per second.
People do not want this.
They want a living wage. They want healthcare. They want to be able to afford a home. They want their basic needs met.
March 5, 2026 at 5:31 PM
So far the war in Iran has cost an estimated $5.5 billion.
That's roughly $1 billion per day.
$41,666,667 per hour.
$11,574 per second.
People do not want this.
They want a living wage. They want healthcare. They want to be able to afford a home. They want their basic needs met.
That's roughly $1 billion per day.
$41,666,667 per hour.
$11,574 per second.
People do not want this.
They want a living wage. They want healthcare. They want to be able to afford a home. They want their basic needs met.
I previously completed the “call representative” item on @robertreich 5 list.
Now, from item 5, “speak out” item
open.substack.com/pub/anengage...
Now, from item 5, “speak out” item
open.substack.com/pub/anengage...
February 8, 2026 at 9:46 PM
I previously completed the “call representative” item on @robertreich 5 list.
Now, from item 5, “speak out” item
open.substack.com/pub/anengage...
Now, from item 5, “speak out” item
open.substack.com/pub/anengage...
chatbots can help search the literautre, but humans still need to produce the literature!
February 2, 2026 at 12:56 AM
chatbots can help search the literautre, but humans still need to produce the literature!
Reposted by Samuel Weisenthal
🚨BREAKING: Minnesota state attorneys alleged in a court hearing that Donald Trump and the Department of Justice are attempting to force the state to surrender its sovereignty — in particular, its control over elections — through the massive federal immigration operation in the Twin Cities region.
Minnesota lawyers argue Trump’s ICE invasion is ‘extorting’ state for voter rolls demands
“It’s a shakedown letter,” one attorney said of Attorney General Bondi's list of demands to the state.
www.democracydocket.com
January 26, 2026 at 8:32 PM
🚨BREAKING: Minnesota state attorneys alleged in a court hearing that Donald Trump and the Department of Justice are attempting to force the state to surrender its sovereignty — in particular, its control over elections — through the massive federal immigration operation in the Twin Cities region.
Reposted by Samuel Weisenthal
Across America and the world, people are realizing it’s not possible to appease America’s dictator.
The only way to deal with him is to stand up to him — and the only way to stand up to him is by joining together against him.
It's time for a massive general strike across the country.
The only way to deal with him is to stand up to him — and the only way to stand up to him is by joining together against him.
It's time for a massive general strike across the country.
January 25, 2026 at 8:01 PM
Across America and the world, people are realizing it’s not possible to appease America’s dictator.
The only way to deal with him is to stand up to him — and the only way to stand up to him is by joining together against him.
It's time for a massive general strike across the country.
The only way to deal with him is to stand up to him — and the only way to stand up to him is by joining together against him.
It's time for a massive general strike across the country.
Reposted by Samuel Weisenthal
The first time Charlie Chaplin spoke onscreen, he implored the people of the world to resist the rising tide of fascism.
Nearly 90 years later, it remains a timely message.
Nearly 90 years later, it remains a timely message.
January 8, 2026 at 9:05 PM
The first time Charlie Chaplin spoke onscreen, he implored the people of the world to resist the rising tide of fascism.
Nearly 90 years later, it remains a timely message.
Nearly 90 years later, it remains a timely message.
New medical statistics TikTok account! In the video below, I give a “no-numbers” perspective on specificity
#statistics #medsky #medicine #tests
www.tiktok.com/t/ZThRmotjV/
#statistics #medsky #medicine #tests
www.tiktok.com/t/ZThRmotjV/
Specificity, no numbers In this video, I will help viewers understand the common statistical concept specificity without any numbers or equations. I will use a graphical representation, which is be ea...
TikTok video by Samuel Weisenthal, PhD, MD
www.tiktok.com
January 5, 2026 at 8:59 PM
New medical statistics TikTok account! In the video below, I give a “no-numbers” perspective on specificity
#statistics #medsky #medicine #tests
www.tiktok.com/t/ZThRmotjV/
#statistics #medsky #medicine #tests
www.tiktok.com/t/ZThRmotjV/
information retrieval (and summary) is not the same as decision making
December 9, 2025 at 2:14 AM
information retrieval (and summary) is not the same as decision making
decision analysis encourages one to consider all outcomes (and their probabilities), including those that involve side effects
statmedhumanity.org/2025/08/25/d...
statmedhumanity.org/2025/08/25/d...
Decision analysis and the pharmaceutical industry
Summary: decision analysis encourages one to consider all outcomes (and their probabilities), including those that involve side effects. I previously described decision analysis, a well-known frame…
statmedhumanity.org
October 12, 2025 at 11:34 PM
decision analysis encourages one to consider all outcomes (and their probabilities), including those that involve side effects
statmedhumanity.org/2025/08/25/d...
statmedhumanity.org/2025/08/25/d...
“Pride cometh before the fall”
- regression to the mean
- regression to the mean
September 28, 2025 at 11:21 PM
“Pride cometh before the fall”
- regression to the mean
- regression to the mean
One of the more difficult/ tedious parts of being a resident in family medicine is keeping track of vaccines for each patients.
September 21, 2025 at 4:58 PM
One of the more difficult/ tedious parts of being a resident in family medicine is keeping track of vaccines for each patients.
Reposted by Samuel Weisenthal
People are constantly asking me — what can I do? Between now and the 2026 midterm elections, here are five practical steps you can take to make a difference.
August 21, 2025 at 10:33 PM
People are constantly asking me — what can I do? Between now and the 2026 midterm elections, here are five practical steps you can take to make a difference.
Reposted by Samuel Weisenthal
The GOP governors of South Carolina, Louisiana, Mississippi, and Tennessee have all sent their states' National Guard troops to assist Trump's occupation of DC.
All four of those states have cities with crime rates higher than DC.
This was never about "fighting crime."
All four of those states have cities with crime rates higher than DC.
This was never about "fighting crime."
August 20, 2025 at 11:01 PM
The GOP governors of South Carolina, Louisiana, Mississippi, and Tennessee have all sent their states' National Guard troops to assist Trump's occupation of DC.
All four of those states have cities with crime rates higher than DC.
This was never about "fighting crime."
All four of those states have cities with crime rates higher than DC.
This was never about "fighting crime."
If you’re going to use an example to help explain a concept, it may not be to your advantage to make the example more complicated than the concept itself
August 3, 2025 at 4:13 PM
If you’re going to use an example to help explain a concept, it may not be to your advantage to make the example more complicated than the concept itself
4 hours debugging code saves you 10 minutes planning it
July 26, 2025 at 8:38 PM
4 hours debugging code saves you 10 minutes planning it
If a trial is powered for blood pressure as a primary outcome, take care when drawing conclusions about noisier secondary outcomes, such as time-to-dialysis.
July 14, 2025 at 2:10 AM
If a trial is powered for blood pressure as a primary outcome, take care when drawing conclusions about noisier secondary outcomes, such as time-to-dialysis.
Reposted by Samuel Weisenthal
Jewish leaders denounced President Trump on Friday for using an antisemitic term at a rally in Iowa the previous evening.
Jewish Leaders Denounce Trump’s Use of Centuries-Old Trope
President Trump said he did not realize that the term “Shylock” was viewed as antisemitic.
trib.al
July 5, 2025 at 11:55 PM
Jewish leaders denounced President Trump on Friday for using an antisemitic term at a rally in Iowa the previous evening.
Hello everyone! I just finished writing a piece on large language models and medical decision making.
I argue that one who sets out to build a chatbot that solves medical problems will ultimately find themselves staring into the cold, hard eyes of evidence-based medicine.
I argue that one who sets out to build a chatbot that solves medical problems will ultimately find themselves staring into the cold, hard eyes of evidence-based medicine.
July 4, 2025 at 12:27 AM
Hello everyone! I just finished writing a piece on large language models and medical decision making.
I argue that one who sets out to build a chatbot that solves medical problems will ultimately find themselves staring into the cold, hard eyes of evidence-based medicine.
I argue that one who sets out to build a chatbot that solves medical problems will ultimately find themselves staring into the cold, hard eyes of evidence-based medicine.
Reposted by Samuel Weisenthal
When bullshiters tell you they will soon be able to make "digital twins" of patients, remember articles like this about how hard it is to model a single cell.
Ewen Callaway reports on biology's rush for AI-enabled 'virtual cells'.
So far it "has a lot of hype, but not a lot of concrete results or a clear path to success".
"I don’t think there is a clear definition of a virtual cell", says CZI's Jonah Cool.
@nature.com
www.nature.com/articles/d41...
So far it "has a lot of hype, but not a lot of concrete results or a clear path to success".
"I don’t think there is a clear definition of a virtual cell", says CZI's Jonah Cool.
@nature.com
www.nature.com/articles/d41...
Can AI build a virtual cell? Scientists race to model life’s smallest unit
Several groups hope to develop artificial-intelligence models that can predict how cells behave.
www.nature.com
June 28, 2025 at 5:49 PM
When bullshiters tell you they will soon be able to make "digital twins" of patients, remember articles like this about how hard it is to model a single cell.
If you’re going to start a statistics phd, write out a Taylor expansion 50 times
June 26, 2025 at 11:43 PM
If you’re going to start a statistics phd, write out a Taylor expansion 50 times
Like this idea that research question should precede regression. Especially in the medical field, patient should always come before model
Great to see this work by John Carlin & @margaritamb.bsky.social on the uses and abuses of regression models finally published. @vicbiostat.bsky.social
doi.org/10.1002/sim....
doi.org/10.1002/sim....
Rejoinder to Commentaries on: On the Uses and Abuses of Regression Models: A Call for Reform of Statistical Practice and Teaching
Click on the article title to read more.
doi.org
June 26, 2025 at 11:41 PM
Like this idea that research question should precede regression. Especially in the medical field, patient should always come before model
Recommend!
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Statistics not as math, but as a pathway to seeing the world more clearly.
Launching in 5 weeks. Sign up now: kareemcarr.substack.com
June 24, 2025 at 1:35 AM
Recommend!