Sam Fernandez
@sgfern.bsky.social
Postdoc in the Kranzusch Lab (DFCI, HMS)
PhD in the Ingolia Lab (Berkeley)
PhD in the Ingolia Lab (Berkeley)
Reposted by Sam Fernandez
🚨🦠 Reviews are in for a study reporting that human interferon-stimulated genes can restrict bacteriophage replication,
highlighting conserved antiviral mechanisms across bacteria and humans. rrid.mitpress.mit.edu/pub/s2c5kn9i...
highlighting conserved antiviral mechanisms across bacteria and humans. rrid.mitpress.mit.edu/pub/s2c5kn9i...
Reviews of: "Human Interferon Stimulated Genes Target Ancient Features of Animal and Bacterial Viral Replication"
Reviewers: J MacMicking (HHMI, Yale University) & S Silverman (Yale University) & K V Narvaez (Yale University) | 📗📗📗📗◻️ • T Nagy (University of Colorado Boulder) | 📗📗📗📗◻️ • J Pogliano (UC San Diego...
rrid.mitpress.mit.edu
August 19, 2026 at 11:42 PM
🚨🦠 Reviews are in for a study reporting that human interferon-stimulated genes can restrict bacteriophage replication,
highlighting conserved antiviral mechanisms across bacteria and humans. rrid.mitpress.mit.edu/pub/s2c5kn9i...
highlighting conserved antiviral mechanisms across bacteria and humans. rrid.mitpress.mit.edu/pub/s2c5kn9i...
Congrats to @courtneyrsantos.bsky.social and @kvnforsberg.bsky.social on a lovely story!
Humans and bacteria share strategies to defend against viruses.
We wondered: could they use each other's genes? Yes, both can!
Bacteria can use human immune genes to defend against phages AND
Human cells can use bacterial genes for viral defense.
www.biorxiv.org/content/10.6...
We wondered: could they use each other's genes? Yes, both can!
Bacteria can use human immune genes to defend against phages AND
Human cells can use bacterial genes for viral defense.
www.biorxiv.org/content/10.6...
Bacterial and human exonucleases mediate interkingdom antiviral immunity
All kingdoms of life have developed strategies to limit viral infection. In humans, interferons induce a suite of antiviral factors that collectively provide immunity. Some human immune genes are homo...
www.biorxiv.org
July 3, 2026 at 2:32 AM
Congrats to @courtneyrsantos.bsky.social and @kvnforsberg.bsky.social on a lovely story!
Reposted by Sam Fernandez
How do human cells defend against viruses?
@sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics
www.biorxiv.org/content/10.6...
@sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics
www.biorxiv.org/content/10.6...
June 12, 2026 at 8:24 PM
How do human cells defend against viruses?
@sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics
www.biorxiv.org/content/10.6...
@sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics
www.biorxiv.org/content/10.6...